i think that the data starting to look better most levered if you think global growth picks up. >> new month maintaining doing its thing. >> thank you for tuning in. ver. "mad money" with jim cramer starts right now my mission is simple to make you money. i'm here to level the playing field for all investors. there's always a bull market somewhere. and i promise to help you find it "mad money" starts now hey, i'm cramer. welcome to "mad money. welcome to the west coast edition of caramerica tweet me at jim cramer can good news put you to sleep there were so many positive developments today there was almost like the market's eyes glazed over.

the dow gained 91 points the s&p only climbed 1.9%. nasdaq barely at all 0.8% where do i even start? this morning kicked off with an interview we did with the chief economic advisor and my former co-host here on cnbc, he explained that the agreement side with china is a lot more far-reaching than most people realize. it actually forces china to change the way it runs its economy to create a more level playing field. he said our relationship with china is quite cordial because the chinese government recognizes that the united states doesn't want to disengage with them. while this deal was being negotiated, the big fault line was repeating those who don't believe china can ever be redeemed so why not just keep hitting them with tariffs forever so wreck their economy and those that think that china can be a good trading partner if they're willing to play by the

rules. call it the engage camp versus the disengage camp and the engage camp just won from the stock market perspective, that is fabulous news financial and tech companies will get a lot more business many tech companies have shied away from china because of the ridiculously lax intellectual property laws. and the promotion of international property theft our financial companies have been shut out. now, the government says that will change. i think that means mastercard or visa might be able to issue credit cards over there or maybe both and j.p. morgan and goldman sachs will be able to have their own franchise partners free of meddlesome -- will allow apple to offer its credit card that we have here and only here there too. credit card's been preyiaying to get into china until now numbers could go up gigantically, which means the group likely has more room to

run. are the $200 billion worth purchases for real well, larry thinks so. >> for both teams, for both sides, this is a pro-growth deal in fact, we think it's going to add to the growth of our economy by at least a half a percentage point in 2020. >> now, reuters is saying with a story that came out mid afternoon that it's a lot more complicated than that. they point out china still has tariffs on the goods they talk about purchasing and haven't polled them back yet it caused the market to reverse hard even though i think the story doesn't even matter. if the chinese government wants to purchase this stuff, they're going to purchase it it's going to happen and given that president trump won't roll back our tariffs until they place these orders, well i would think they have a pretty strong incentive to keep their word, don't you? the stocks rally hard. stocks like the transports tell me the market agrees with me the transports to my barometer and they finally broke out to a new high

you know i like union pacific but have you ever considered buying fedex it just got to the point where it could be immensely profitable before the trade war pretty much shut them down now, fedex can make a comeback and its stock was actually down today. down a lot off almost three bucks. i'll have more about that particular segment of the economy later on the show. stay tuned many have doubted the prospects of companies that spent fortunes to export liquified natural gas, lng, but they will be rewarded with a huge customer base that could easily get hooked on our nation's plentiful natural gas hey, we're the lowest-cost producer in the world. make tellurian don't forget, we make more than just plains and heavy machinery. the chinese can buy medical instruments like the ones i heard about at the j.p. morgan health conference. honeywell, nice move today

united technologies, a ton of merchandise to sell. needless to say, apple's a winner, too. in case you need more companies, the president named dozen of them in his press conference today. which, at times, felt like he was reading a list of the fortune 500 and asked them why they hadn't thanked him. all the while he kept the chinese there waiting. i don't even know which one to -- it was all very good for stocks but the market's collective eyes glazed over. but there was plenty of new stuff here that got completely ignored or that the media chose to ignore because, well, it's hate 'em or like 'em, it's positive for him i'm speaking of trump there. consider the banks today, we got some incredible numbers from goldman sachs and bank of america. these quarters were treated as a real snooze fest because you already got great results the other day. i kept going over the results saying what am i missing the answer, nothing! nothing but -- we saw the same

delayed reaction to the stock of united health. unh. cramer fave. okay i'm watching and i -- i got my reckless 45 minutes of sleep and the stock sunk almost immediately when they reported i'm thinking, oh, man, maybe i'm just too tired not! the numbers components were extraordinary. it finished up eight bucks hey, moron -- i'm sorry, jimmy cho, hey people who mistakenly sold that sock when it was down, that was ill advised i think these moves may not be done this is day one of a much better than expected trade deal and larry says there will be more deals because the chinese need them. they need to get rid of those tariffs. since larry came into this job, you know, he's been raw. two stocks finally came down tesla! and beyond meat. this year, it's like 45 minutes

old. i'm a believer in both these stocks but enough already. parabolic moves are unsustainable. and the only disappointment did kind of shock me, target effectively blew up. showing a dramatic deceleration. some same store sales growth for the holidays with the misconcentrated in electronics, toys, and home. i think these below expectation categories cannot be explained by a weak consumer but by encroachment of amazon and the uber cramer fave costco. coupled with the dramatic sales of the apple iphone -- the 11. which i keep telling you is a game changer but you won't listen to me yes, it could be so big that it's pulling sales away from other big-ticket items that's the way it works. we don't have -- i can't even reveal how much it cost. to me, here's the issue. even with the all-time highs,

the president of the united states singled out at his press conference simply refused to run up dramatically in spite of market-moving information. and i think that's all about we. he put out a by-list today i'm not kidding when he was doing it, i'm thinking bye, bye, bye. look, this is not a political show on "mad money," i'm in favor of anything that results in higher stock prices and that is exactly what this trade deal does. don't let anyone else tell you differently. they don't understand stocks and they don't understand companies. the bottom line. if the stocks of any of these companies with new access to china get hit, i think you need to be a buyer in the weakness. i'm just hoping the market's general sense gives you that opportunity. i feel like taking some calls. i think we should go to julia in new york julia! >> hey, jim. i love your show. >> thank you, julia. >> i'm calling about target.

i bought it this past spring based on your watch stock recommendation. >> right. >> and it's been doing great until today. and i was wondering if you -- what -- should i take a profit is the market overreacting >> okay. julia, here's what typically happens. when you have a stock down this much, it means that sellers were still trying to sell even at the bell i think the sellers will come back i don't think they're done i do think that the company is a great company. i think they've missed the mark with the merchandise but i'm not giving up on brian cornell. that would be mistaken i think the market -- too much on positive moves today and we have moves i think are not done. you know the phrase don't take it personally? i'll tell you why maybe you should in the world of fast fashion that ends up in a landfill can stitch fix leave a lasting impression i got a chance to sit down with the ceo at the company's san

francisco headquarters after the close, remember i teased with the fedex thing? nasa explores have teenagstrat l alternatives that's called an exclusive stay with cramer. >> follow at jim cramer on twitter. have a question? tweet cramer #madtweets. send jim an e-mail to madmoney at cnbc.com or give us a call at 1-800-743-cnbc miss something head to "mmadmoney.cnbc.com. >> record market highs check on a tear. and the trade deal impact. can the rally continue squawk on the street 9:00 a.m. eastern on cnbc. you take a lot of trips to the islands, phil? pretty great, right?

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silicon valley, i try to find where people are spending lots of money and what's driving it sometimes it's hard to see the data center. the cloud. 5g stuff that's not in your face as a consumer at least not yet sometimes it's obvious social media artificial intelligence. the ingenuity for apps and mobile and mobile itself this time? this time, it's personalization and it is everywhere

i'm here for the j.p. morgan healthcare conference. and i'm constantly struck by how medicine, particularly cancer medicine, has become tailored to the individual there's so many different forms of cancer. it's a really big rubric we've always been tacking this with the equivalent of nuclear war heads. the treatment would have killed her in the process today, though, i'm hearing over and over about these car-t immuno therapy drugs that can search and destroy cancer cells while leaving healthy ones intact we have drugs that transform your own immune system into a cancer-killing machine while leaving rest of you basically untouched. it's science fiction it's revolutionary especially when you consider that we can now map our own genes to figure out which types of cancer we're most at risk of developing knowing what you have in your own body allows these companies to personalize the cure.

and i do mean cure maybe the most important personalization i heard, which is dep developing personal cancer vaccines. can you imagine blocking the cancer you're most susceptible with a shot in our lifetime? incredible later but i'm pulling away it's not just medicine we're seeing it in retail, too now, when you think about the strategy at, say, cvs, they're trying to get you to tell them what you need so they can steer you in the right direction there's so much confusion in the drug store right now because there are so many options. they can give you the answer well, that's best for you. the one that's right oh, come on, that's huge or how about stitch fix? here's a company that's basically using stylists with algorithms to tailor your wardrobe to your own taste there are too many choices in apparel out there and most people have trouble finding what they want. that's why shopping can be overwhelming for lots of people. stitch fix helps them by offering a curated --

hypercurated set of goods as a subscription service finally, i am seeing the power of personalization technology to help grow your franchise look at bank of america. they a fast-growing deposit base we learned that on their conference call. because bank of america has the leading personalized banking business and the best mobile app which results in tremendous customer satisfaction. way higher than it used to be for them by the way, i see the hand of salesforce in that, the software company that's turned it into a science. meanwhile, i wells fargo is struggling sometimes they get too skeptical and i worry this stuff is all for show personalization is really a silicon valley buzz word but then i realize if your business isn't personalizing and the other guy is, you're going to get eaten alive personalization is a lot more than a buzz word it's become a necessity.

all right. much more "mad money" ahead. remember i mentioned stitch fix? i'm going to bring them on and i want to know if you think they dress to impress i got a chance to sit down at the company headquarters not just our place -- to see for myself after the close tonight after it announced plans it is considering strategic alternatives, i got the ceo after the news. >> and it's a chase in the next frontier in treating disease i just mentioned moderna it's shaking up the whole biotech space so stay with cramer

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sends you clothes on a monthly basis. their technology allows them to know what you want better than you know it yourself stitch fix has been grown by leaps and bounds but over the summer the company now making some big investments in its platform that aiding their new-found profitability. but it happened just as the market was turning with rapid growers with no earnings in the last few months, the stock rebounded from 17 to 24. i think it's got more upside earlier today, we got a chance to speak with stitch fix's founder and ceo, katrina lake, at the headquarters. >> katrina, you are a company with 3 million customers doing about $2 billion in business i still find there are too many people who don't understand what stitch fix is doing and how it's changing the entire retail world. >> yes so we -- we have a huge business and we have 3 million clients out there. and really, what is differentiated about us versus other apparel retailers is we are solving the paradox of choice and really figuring out what is

right for you, uniquely you, individually and so, as an example, jeans like, you know, nobody wants to be trying on dozens of pairs of jeans and online nobody wants to search through literally a million pairs of jeans to try to figure out what are the right ones for you and a model like ours is able to use data science to understand what is about you, what is it about the pair of jeans and match you really smartly with jeans that are going to fit you. with us, we ship product to your home you let us know who you are, what you're looking for. we'll ship product to your home. you can try things on at your home it's a very effective and efficient way to beable to find clothes that you love. it's not just an algorithm that is putting the jeans in the fix. we have stylists across the country. the stylist is using the tools that we have so she or he is able to be able to smartly choose things for you. but it's a dynamic relationship and our clients share with us when they try things on, this is

working. this isn't working and it really empowers our ability to get to know you over time >> we see a lot of companies out here that seem -- in losing money. that's never been your style. >> sure. we've been profitable since 2014 even during this time, we've been using that profitability to put it back into our business and expand our business into men's, the uk, kid's we are now doing some product innovation so our philosophy has always been we want to be able to be profitable and reinvest that profitability into our future. >> i can't see because i'm a man and it doesn't let me even though i love to shop. direct buy we need to talk about that we need to talk about how you're able to shop your way, colors. let me in. tell me. >> so historically, all our product has been selected by a stylist on your behalf so there has never been, as a client, an opportunity to be able to click and buy something. so we're changing that with

direct buy so what direct buy is it is still entirely personalized for you. so you are only able to see. you, only to our female audience we are gradually rolling out and testing it and we will get to men's i believe this year. but on the women's side, what you can do is log in and see outfits that are curated just for you. so you're only shopping 30 or 40 things you don't have the paradox of choice you're not filtering through millions of things and these are things we have a high degree of confidence are going to work for you. you can be inspired, click and buy. so you can really capitalize kind of on that i want it moment but i think it is also this experience of a totally personalized world and what shopping in that world would look like. >> in a personalized world, you don't need to see a million clothes. so that would mean one les landfill. >> yep. >> carbon footprint. >> that's another interesting part of our business is we are actually using the data we have to be able to buy less product buy product that we know there

is demand for. so we are able to smartly buy the right product, get it to the right people and through that, it's better financial model. we're able to drive more profitability that way it's a better model for our clients. our clients are finding more things they love and it's a better model for the environment because we're not creating product that's not going to have a happy home so we're really happy about that part the carbon footprint part is very interesting too we did a study where we compared ourselves to other retailers, billions of dollars to billions of dollars to understand shipping product back and forth, is that worse than a store and what we found is fascinating, which is that these stores, these huge retail stores that are, you know, millions of square feet across the country that are heated and cooled 365 days a year. that is actually a far worse carbon footprint because especially these days those stores are doing a lot less in transactions there is a lot less kind of productive -- productivity happening there. and so it's a very interesting story. not just from a product

perspective but even from a business model perspective. >> how about competitive landscape? what is your mote versus the king, amazon >> so our mode is really -- i mean, it's focus on personalization and a focus on apparel. but on the -- on the fix side of the business, we've sold $5 billion of clothes sight unseen. you have to be really good at personalization if you are going to proactively ship clothes to somebody's home and expect them to buy them. that is a muscle we've built over the last eight years that's really differentiated. the data we get from our clients is really differentiated so yes, there are players out there that have far more in terms of volume of data. but the data we have is you saying i love this color, you know, i like this but i already have this in other colors. this is too short. whatever the feedback is and that really accurate feedback is what helps power our model and is very

differentiated. >> when i measure retailers, i look at same store sales for instance, today, target had a very tough number. deceleration can i do a same store sale per customer with you? where the customer's doing more business year over year? >> i think our revenue growth is probably the right comp. i mean, on a target world, like are you looking at it customer by customer? no, you're looking at how productive is their kind of facility, right? so for us, i think that's probably the best way to see it if you're going to think of it that way but i think -- i mean, i think one of the challenges of being a newer model is that i get questions of like. like, i have a model you know, i am an analyst and i have a model around same sales with stores and how do you fit into this? and the reality is i think this is a new model direct to consumer in general is a new way to look at how people engage with apparel and i think we're in the beginning stages of figuring out what are going to be the right ways to measure >> well, but can we grade you to some degree when you get a customer, you have their wallet so to speak. are they buying more over time

than the first year? >> right so revenue per client is probably going to be the best metric you can look at so we have had six consecutive quarters of revenue per client growth and that is also a signal of how good are we at what we do? like if we are able to get more product to you that you're keeping, you're spending more with us, it's a sign that kind of of our business is doing better. >> why can't -- why can't macy's do what you're doing i do think nordstrom's is trying to make a turn but when i look at what the so called dinosaurs are doing, they don't need to be dinosaurs they could have done stitch fix. >> so firstly, like i really have so much respect for the ceos of these companies. like, it is such a challenge to figure out i have all these stores and i have to close some of them and i have to rationalize my business model and i have to invest in innovation like, that is a really hard job to have. so i have a lot of empathy i think for how challenging that is and the reality of that is like

we are so lucky that we get to be in a seat where we get to reinvest all our profits against innovation and what's next and what's new and, you know, i think that's an easier place to be able to operate from i think the reality of trying to shift your business from one really significantly different business to another is -- it's challenging. >> you're still getting good bang for the buck? have you been able to -- have to spend more to get more customers than you would like at this point? >> so, you know, on the marketing side, we -- we've been very proud of our marketing efficiencies we've shared in a disclosure, i guess, now two quarters ago that we are getting very quick payback on the marketing that we are spending and that's been true for the entire course of our business. we wouldn't have been profitable since 2014 if we didn't see that significa significant marketing efficiency i think what we're doing now that's different that we're more smart in the way that we spend and so we actually can now see there might be a client that might cost a lot there might be a client who might be $150 to acquire this client but we actually know that that client is going to generate a lot of value for us.

and we can be predictive with that and years ago, we may not have been able to identify that that one client is worth spending on. and now, we're able to do that and so that's really more of the way that our marketing has evolved is to be more personalized and more data driven, frankly. >> those are the two i think of. personalization is incredibly important. and choice helping me with choice by using big data is a pretty good way to do it. >> yeah. it's a great way for 3 million of our clients to do it too. >> katrina lake. she's the founder and ceo of stitch fix once again, a profitable company. 3 million customers. almost $2 billion in sales not some company that's just got some dream that you might want to buy. >> thank you where does the trade deal deliver new opportunities for tech investors a look at the companies wall street will be watching. tomorrow 6:00 a.m. eastern on

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very big news from one of our long-time favorites. xpo logistics. that's that roll up created by brad jacobs to consolidate the trucking industry. it's reviewing strategic al t n alternatives now, regular viewers know xpo has been a fabulous long-term performer. on the rise ecommerce.

but in the past year and a half, the stock has struggled. still hasn't fully recovered at this point, though, management's gotten impatient. they believe their company's urc undervalued so they want to find a buyer for all or part of the business let's take a closer look with brad jacobs, the chairman and ceo of xpo logistics to get a better sense of what he is looking for from this process. mr. jacobs, welcome back to "mad money." >> great to see you, jim. >> all right brad, people made fortunes with your stock i mean, it's up more than ten fold since your investment in 2011 why now? and does it necessarily mean that you're done >> no, we're not done. so first of all, thanks for having me on so the -- the company has -- the stock has performed very well. it was the seventh best-performing stock of the fortune 500 of the last decade but we're still getting a low multiple so as a diversified company, the

market's only giving us an eight or nine times multiple when you look at what we would get if we sold off or spun the four of our business units, each one of those as a smaller pure play would get a higher multiple so when you do the math, objectively, it creates more value by spinning off or selling those four business units. now, we're not interested in selling ltl. we're not marketing ltl. and we're not marketing the whole company. we're marketing those four businesses north american and europe, transportation, logistics. >> well, my feeling, brad, is that somebody else has put pen to paper a large company, and said, hey, brad, i'll buy your company for -- i don't know -- 7 billion. i'll buy 10, 11 billion. have you been contacted by someone this large >> well, i don't want to comment on those kind of discussions but what we're doing proactively, i think, is the best way to create a significant amount of value in the stock holding auctions and going through a professional process

for each one of those four business units >> well, brad, i got to tell you i was looking at what fedex paid for tnt or overpaid for tnt if i know you five years ago. they paid six times ebitda for that one really very poorly performing business versus what you have in europe brad, that means your stock will be worth -- well, i mean just that one division will be worth $14 billion. how do we rationalize what's going on here? >> well, we'll see how the process plays out. and we'll see what kind of market there is. and then we'll see how the numbers shake out. >> how is business because you are the ultimate last ecommerce play. >> business is good. the industrial economy is still chugging along it's not been very robust. but i'm sensing a bottom there i don't see it being booming but i'm sensing a bottom it's not getting worse the consumer part and the retail part is obviously very, very strong and of course ecom is growing like gang busters all across the

globe in all of our businesses. >> well, look, brad, the division i like is the logistics division the one that credit suisse called in october the google of logistics. tech platform is difrptferentia and scalable brad, people don't understand you spent hundreds of millions of dollars making this the ideal platform what do you think that particular business could be worth? >> i -- i don't want to speculate what we'll get you never know on these auction processes. but the leadership positions that we have in each one of these businesses and particularly there and the strong position we have in ecommerce, in reverse logistics, in omni channel logistics. i think there will be strong demand for it. we just have to be passionate and not be attached and not have an entrenched management perspective but have a shareholder value creation focus which is what we have. >> you have been one of the most

aggressive buyers of your stock. when it was much lower -- i'm going to use the term, raided your stock, it gave you a chance to be able to puttu your money where your mouth was. >> so that is a good example of us being agile us being opportunistic us being rational and willing to do bold things that create a lot of shareholder value even if it's not conventional. we did that, if you recall, back in 2015. we saw a company conway, which is a big ltl company, and it was very much out of favor and we saw an opportunity to buy that and we then did. and we doubled the ebitda within a couple years so it created a ton of value and then with the share buyback when the shares got dislocated, we bought almost $2 billion of stock back in the '50s so that's worked out very well, too. so now, we see the next leg up the next opportunity to create some significant value is to construct processes for each one of these four business units and let's see what -- what kind of

prices buyers give us. >> okay the stock is trading up substantially after the bell instantly, people -- i mentioned you're going to be on and said, jim, come on amazon has contacted them or amazon's going to buy them just makes too much sense. i know you can't contact -- talk about any specific company and you said you can't talk about who contacted you. but you got to give me the opportunity to at least say that amazon would pay a lot of money to own xpo logistics. >> i don't know about that you're going to have to ask jeff bezos about that. >> i might do that you know, in the next 48 hours i think that can actually happen why not? why not? i'll be up there you bought europe at the bottom. what's europe like right now as we get ready for brexit? >> well, we got to see how brexit plays out i mean, i like the fact it's making progress and getting clearer. it's got to come to a resolution when we talk to our british customers, they're dying to invest in the business and put more cap x and expansion in but they're hesitant to do it until brexit is behind them. there's more clarity on it

when brexit finally gets resolved, i think the uk is going to really explode in a positive way but it's not there yet >> well, you've been -- you're in a group, frankly, where i've seen in the time since you started, there was the dean of the group, fedex and they have been whip sawed every which way and the situation's kind of devolved into basically a shouting match between analysts and fedex how have you been able to avoid what i think is a very contentious situation between the industry and the analysts where everyone recognizes your company's worth a lot less -- a lot more than your companies are and not a lot less >> well, we try to make peace and not war with our competitors, as well and fedex, by the way, i think is a fantastic company i mean, the brand is so strong and, yeah, they've got some little tough times right now but that happens it happens to every company. and -- and you work through it and you bounce back afterwards >> well, it hasn't happen to a lot of your companies, brad.

i mean, you put together this company. a lot of people thought it was too difficult to put together. everything you put together was additive and you are still only scratching the surface on a lot of divisions so it seems to me you must have avoided some of the pitfalls some of the markets that didn't work out. >> we kept our head down we tried to tune out the nay sayers and over the last four years, without any acquisitions, we grew the business $2 billion on the top line and $500 million on the ebitda line. so the team has executed very, very well globally >> well, look, i think you've done a remarkable job. and, frankly, is an incredibly difficult environment. again, i have to come back to that the company has been up ten-fold since your investment in 2011. that is a remarkable figure. brad jacobs, chairman/ceo of xpo logistics. thanks so much for coming on "mad money." >> goodto see you, jim thank you. >> "mad money's" after the break. a golf course is designed to be difficult.

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and then the lightning round is over are you ready? lightning round question anthony in michigan. anthony! >> anthony out of detroit, michigan look, i have a strong position in pfizer. and it seems stagnant. and i -- i -- i don't understand why it's not making me any money. >> well, it's not because it's not doing anything that should be making you money, man i suggest, kind sir, that i would easily swap into bristol meyers i'm going to craig in north carolina, please craig! >> boo-ya. i'm calling about next-era energy. >> oh, my favorite nextera. they aren't your father or

mother's utility masquerading as utilities! how about going to pat, please, in california. please, pat. >> hey, jim. to you from southern cal i got a question for you on aaxn taser. i've been with it quite a while. i've tripled by money and i'm thinking about putting some more in what do you think, buddy >> i don't know. it's really an ecosystem, not a platform and i feel pretty darn good about it remember, he's incentivized having the stock go up so i'm going to agree with you that it's a buy now, i'm going to jack from ohio. >> thanks for taking my call, jim. i need your help i'm looking to -- i'm looking to add a solid dividend income stock to my holding. >> don't don't. my chapel chest owns it. i don't know if you recall what the guy who runs black rock was

saying but they're an ex-nay. and this one, my travel trust owns it and so far, it's been a loser. sean in indiana. sean >> mr. cramer, good evening, sir. just want to say thank you from indiana for all that you do for investors each and every day. >> just saw mark cuban from indiana just last night. good to talk to you. >> good to talk to you want to get your take on viking therapeutics wanted to know if this was a good one to get in on. >> no, i tell you the street's not all that poz tib abositive . again, i'm going to default to suggesting bristol meyers and advi i know they're boring. how about daniel in new jersey daniel. >> boo-ya, jim, from new jersey. i'm calling in reference to

royal caribbean cruise line. >> i like what he's doing with royal caribbean. it's flat for the year that could be an opportunity let's go to somebody in washington gary in washington gary. >> hey, jim. thanks for taking my call. first-time caller. >> got ya. >> hey i just bought some march -- i'm sorry april 125 calls on microchip technology >> right well, you know, that's an options action there 5:30 on friday but i would say already preannounced the earnings. not much there that concludes the lightning round! >> the lightning round is sponsored by t.d. ameritrade ♪

♪ ♪ but in my mind i'm still 25. that's why i take osteo bi-flex, to keep me moving the way i was made to. it nourishes and strengthens my joints for the long term. osteo bi-flex - now in triple strength plus magnesium.

about the power of personalization here at the j.p. morgan healthcare conference and at the van guard of this movement are companies like moderna. this is a revolutionary biotech firm creating a whole new class of medicines based on rna. they're trying to reprogram ourselves to cure everything from cancer, cardiovascular diseases, and rare genetic disorders. it's been awild trader

i think it has a ton of potential. so earlier today, we checked in with stephen van cell. he is the ceo of moderna so take a look. >> stefan, i think it's fair to say that i found your presentation maybe the most exciting at the entire conference and one of the reasons is because you have a new class of medicine. >> thank you, jim, for having me and thank you for your nice comment. yes, we are very excited since we started moderna now eight years ago. the vision has always been very crisp. if we can make rna work safely in humans, it would be a very broad platform a new class of medicines where we can go after cancer, rare disease, and many more. >> many people have rna and it's all on the drawing board it's all whiteboard. it's, frankly, not ever going to get to us i think. you are incredible you got -- go into phase three on what could be a 2 to $5 billion opportunity now.

>> yes, so we are very excited we have a vaccine we just presented the clinical data last week against cmv it's a virus that if infects a woman during pregnancy, will be transmitted to the baby and have massive impact on the brain development of a baby. it's the number-one cause of birth defect in this country. >> number one. people have not heard of cmv, you need to know that you are attacking something big, not orphan. >> correct, very big and we believe that every woman in the age of bearing a child in this country should get vaccinated once this vaccine gets launched. >> it reminds me how much glaxo is doing with shingles. >> yes, a wonderful vaccine glaxo got approved a couple years ago. actually, sold a billion dollar first year of launch, which is quite remarkable and going to grow into a multibillion dollar product. >> merck happens to be a

partner. biomedical advanced research and development to you, gates foundation looked to you for what you are doing. >> yes, i think everybody that has tried for many years to find a new technology to do vaccination right. if you think about it, there's still a lot of viruses for which we do not have vaccines yet. and if you think about it from an economic standpoint, actually best returns on healthcare dollars. >> right and i think what we have to recognize is that what you're doing doesn't cost nearly as much money as typical tests and produces a far better return on equity >> yes i mean, the piece that we have is a platform. and if you think about the pharmaceutical industry, never been platform. meaning what you do in the science in the labs on the one drug, you can use on the next drug. >> stephene, we have to talk about personalization of medicine personalized cancer vaccine in

our lifetime >> yes, it's happening actually right now with a phase-two study going on where we are designing every product for every patient. so we start by taking biopsy of a cancer we next-gen sequence it. we next-gen sequence a healthy cell of their body we send everything to aws. we compare every letter -- >> to? >> aws. >> amazon web services and they do? >> we compare every letter of dna. of the cancer cell and the healthy cell and from that, we deduce what do we need to do in a product just for your cancer >> i find it's almost -- it's almost science fiction what you're up to. >> yes, and it's happening now and goes back to this platform we do not have to figure out how to make, in a factory, each product. they are the same. mrna is an information molecule. it's a software of life.

there are -- that makes every one of our drugs that goes from product one to product two. so once you figure out how to make it work once, then you can have a lot of new products coming very quickly. and the return investments is very spectacular because you don't have to reinvent everything you just fly. >> that's how you can have 20 drugs in development just in a few years time >> correct last four years. >> i think it's incredible i also think that when i look at what you guys are doing, one that hasn't been a problem right now but was a huge problem zeka. >> yes, it's part of the company's mission, which is of course we want to invest capital to do great product like cmv but we think we have responsibility to make sure that vaccines like a vaccine against zika are developed and for this, we partner with government this is paid by the u.s. government or foundations like the gates foundation to use their capital. but we make the platform

available for free and develop a product. so the zika vaccine is in the clinic because zika, unfortunately, is going to come back one day nobody knows when. nobody knows where but ebola and thank you now merck have approved ebola vaccine. that's very important. >> you're working on amazing things just to sum it up, you -- you are basically about to go into a -- into phase three in what i think is actually record time for a mass product. >> yes, and again, go back to the platform, which is in traditional medicines, you have to have teams of engineers figuring out how do you scale this product in the factory? >> right. >> with us, it's always the same so we can move very quickly from the lab to phase one to phase two to phase three to commercial very quickly. >> i wish people understand how hard it is to -- to do a typical drug now, your drugs could be -- vaccines are far more effective than pills. >> yes and if you think about all vaccines versus traditional vaccines, because you make your

own protein in your own cells, it's like a natural infection. >> right. >> when you get infected, the virus your your cells to replicate. so we do exactly that. >> well, i got to tell your story. i got to tell your story to everybody because this is the kind of story that people have to recognize is happening in our lifetime and i didn't think it could. i want to thank you so much for what you do. >> thank you very much. >> that's stefan he is moderna's ceo. you can read it. you can find out what this company is doing i think it will astound you. it astounded me when i read it stay with me make fitness routine with pure protein.

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♪ everything your trip needs for everyone you love. expedia. for everyone you love. it's almost like a challenge everyday myww's been an amazing journey. to see how well i can eat and still enjoy myself all day long. i wake up every morning to see how much weight i've lost and how much better i look. myww join for free and get two months free! the deal is real and don't let anyone else tell you otherwise. i expect it to be additive maybe not as much as larry kudlow but it's going to be very, very good for business i like to say there's always a bull market somewhere and i promised you i'd find it just for you right here on "mad money. i'm jim cramer and i will see you tomorrow

narrator: it's been 10 years since "shark tank" ignited america's entrepreneurial spirit, and we are still blazing a trail. for those who take their fate into their own hands by working hard... who wants to get naked with the shower toga? narrator: ...by thinking big... simon: zookies cookies are the most delicious treats you have ever had. ...and chasing their dreams. woman: introducing goat yoga. [ goat bleats ] oh, lord. what? narrator: and tonight, alli webb, the founder of the beauty powerhouse the drybar, joins the tank. from being in the hair industry for 20 years, i think there's a good business here. what are your sales? -$40,000 in sales. welcome to "shark tank." we cannot keep products on the shelf. i'm willing to make you an offer. no! captions by vitac --