japan. tokyo in the 36 celsius. 87 people have been admitted to hospital across japan because of this heat wave. look at the women dressed in summer kimonos out there. they splash water onto the streets across portions of the ginza shopping district in tokyo. the warm weather not only kids find weigh to cool off. we know the typhoon will bring in some rain that will help with the temperatures. but unfortunately the flood's going to be very disruptive in that region. >> thanks very much. israel and hamas preparing for peace talks in cairo today. >> we're talking about why egypt's new government has stepped in. and what they have at stake as well as they try to play this role of peacemaker. plus it's a serum that could potentially change the future of ebola treatments. we're going to take a look at something called zmap ahead.

israeli and palestinian negotiators are in cairo today for what are being called indirect talks to bring a lasting peace inside israel and gaza. >> they're not actually speaking with each other, but egyptian officials are expected to act as the go betweens since israel and hamas are still refusion face-to-face talks. egypt also has a huge stake in the process as well. >> our global affairs correspondent elise lavit reports. >> reporter: palestinians digging through the rubble that is now gaza look to egypt to help open the territory they have come to see as a prison. >> we need the human passage that links us to the world. we need to give our people in gaza some hope.

>> reporter: egypt has traditionally been the center of gravity in moments of diplomatic crisis. president hosni mubarek served as a bridge between palestinians and israelis. he brokered the deal that released israeli soldier gilad shalit. hamas had a friend in former president mohammed morsi who opened the border with gaza and with secretary of stays hillary clinton brokered a peace between hamas and israel in 2012. things have changed since then. like israel, egypt's current president views hamas as a regional group and threat. isolating them politically, sealing off across gaza and destroying tunnels between the borders to stop hamas from smuggling weapons. >> the reason both egypt and israel have put restrictions on the border is because we don't want hamas to do that. as long as hamas doesn't want to

invest in the people of gaza but wants to invest in its terrorist war machine, of course those restrictions have to stay in place. >> reporter: with monday's cease-fire, egypt once again assumed its role at mid east power broker. when talks resume in cairo on a long-term truce, egypt holds the key to helping ease the blockade of gaza while helping to deny hamas the ability to rearm and attack israel. >> egypt is not just the negotiator. hamas has spelled out their leading demand is an end to the siege, what they call the siege of gaza. and they're looking to egypt to open up the rafa border crossing. so egypt is in fact a party to this cease-fire negotiation. if you want this to endure, then egypt is going to have to pony up something. >> reporter: egypt blamed the failure of last week's cease-fire on the decision by secretary of state john kerry to bring qatar and cur tee into the diplomacy. but the u.s. still considers the

indispensable broker of middle east peace talks when they get started. u.s. officials say we're a long way from that. we have to make sure the cease-fire holds first. elise labott, cnn, washington. now israeli spokesman mark regev insists the key to any negotiations is that hamas must disarm. we bring in our senior international correspondent matthew chance now joins us live in jerusalem with more on this. here we are, matthew, at least one day into a cease-fire. hamas wants a reopening of border crossings, fishing rights extended and the like. israel of course wants to disarm hamas. how hard is it really now for both sides to get what they want here? >> reporter: i think, erol, it's going to be very hardin deed. because there's a fundamental disconnect between how the two sides, the palestinians, hamas, the militant groups, and israel see a settlement to this crisis. you mentioned israel is

basically saying, look, if you stop firing rockets at us, if you stop your aggression towards israel, the situation can be calm. if you don't, we'll go back in and conduct the same kind of military operation that we've seen illustrated so brutally over the past four weeks. and from the palestinian point of view, what they want is a kind of end to the occupation. they want the borders opened up so they can travel freely out of the gaza strip. you mentioned they want their fishing rights extended. they want the blockade as they call it, the siege of gaza, to be lifted to allow the free flow of goods in and out of the gaza strip to alleviate the humanitarian situation there for the people of gaza. and so there's this disconnect in which both sides appear to be unable to give the other what they want. what that will lead to in cairo if these negotiations ever get under way in earnest is some kind of compromise which satisfies neither side and which

will essentially set the scene for another confrontation at another point in the future. >> what about the mood throughout israel? some analysts tell cnn that it's really a draw between the two. even if israeli citizens see this as a win, surely they don't want to have to battle hamas once again. of course the idf sustaining deaths of 60 plus. is there possibly a renewed support there now for a peace plan to keep the peace? >> reporter: well, up wouldn't say that this conflict in term of what i'm observing on the ground in israel has led to a renewed push amongst people in general in israel to sit down at the negotiating table and to do a deal to implement a two-state solution and to decide the terms of that. i mean, having said that, there have been some protests against the conflict in tel aviv among left wing israelis, anti-war campaigners. but they very much represent the minority, i think it's fair to

say, inside israeli public opinion. polls suggest the vast majority of the people here support the policy of the israeli government, a policy of essentially saying, look, if the violence stops against us, there'll be calm. if it doesn't stop we're going to go in overwhelmingly. that seems to be what the people of israel in the most part support. >> well, at the very least the cease-fire has held almost for 24 hours now. so i think people on both side will take what they can get. matthew chance, live for us in jerusal jerusalem, thanks, matthew. we also return now to one of our other top stories today. a second american infected with the ebola virus is now getting treatment at emory university hospital in atlanta, georgia. >> speaking of nancy writebol, she was given an experimental serum before she left liberia where she was helping care for ebola patients. now a spokesperson for the group sim usa says the missionary is still very weak. she's not out of the woods yet. however, she is showing signs of continued improvement.

writebol joins her colleague dr. kent brantly already being treated at the hospital's highly specialized isolation unit. >> brantly was also give than experimental serum we've heard so much about. it's called z-map. it is so new it hasn't even been through any clinical trials which is on the way of getting it approved for widespread use. >> right. but this is such an urgent need now they thought they would test it out. doctors say the impact appears to be positive. cnn's stephanie elam has more on this special serum. >> it's profound. >> reporter: erica allman sapphire is part of the team of 25 labs in seven countries that created the serum taken by both american ebola patients. so far, the cocktail seems to be working. until now, the drug wasn't known to the public. it wasn't even supposed to be tested on humans until 2015. >> did you have any reservations before this outbreak happened about trying it on people? >> i thought it would work. i would take it myself. but i know what it is, and i've spent my life studying ebola

virus. >> reporter: sapphire says the anti-bodies bind to the virus or infected cell. >> this is a model we made with our structural biology of the structure, this protein in the surface of the virus, it's green and white. yellow is the anti-body. so this is the molecule the virus uses to attach to a human cell and drive itself in. the anti-body will attach itself to it and do one of a couple things. one of the ones in the z-map cocktail alerts the immune system to the presence of an infection. the other two do exactly this. they bind to the base of this molecule and prevent it from working. >> reporter: one reason it takes so long to make doses is the need to recreate the ainnti-bods the scientists can do with tobacco plants. >> they're taking hundreds of plants at a time, dipping them into this genetic solution. the plants take up the virus. they start this process of viral infection. and in the process, get jammed full of anti-body.

as the plant starts turning yellow because it's going to die from the viral infection, once you see the plant has gotten to that point, the guys in kentucky harvest the leaf material. >> reporter: after separating the anti-bodies through a multi-step process, the three desired anti-bodies are then combined to create the drug that the americans, dr. kent brantly and dr. nancy writebol received. it's called z-map. >> it's certainly encouraging and a reason to go forward with these kind of studies. >> reporter: dr. dr. sapphire said it brought a tear to her eye when she saw dr. brantly get out of that ambulance and walk under his own power into the hospital. that gives her encouragement this cocktail is working. but because there was no control and these were the first two people ever to get a trial version of this drug, she says that more trials need to be done, more studies so they can get more information and hone this drug as necessary so that more people can benefit and more lives are saved. stephanie elam, cnn, la jolla,

california. >> thanks, stephanie. we get more now on this new ebola serum. arthur kaplan is the director of medical ethics at new york university's langone medical center. he was nice enough to join us from vacation via skype from denver, colorado. or steamboat springs, right? >> that's right. >> thanks for being with us. the interesting thing, we've heard a lot about its surprising results that there was just a one day after taking the serum an improvement in at least two of the patients. you had an interesting story about where this came from and why putting it into widespread use at least right now is an extremely large challenge. >> well, you still have a highly experimental drug. it's great, almost unexpected that it would do so well in the first two humans who got it. it's really only been given to a small number of monkeys, success there. but to bring a drug forward really so you know how to use

it, what the dose is, how to administer it, how often to give it you have to test it on a lot more human beings. we might try this drug on children, very old people. what are the doses for them, how they're going to respond again unknown. so very promising, very exciting. but we're still in the early stages of human experimentation here. we have to remember that. >> this is the other interesting thing. this is not necessarily the control of let's say the cdc, nih, the fda, any of the organizations in our country that work to help regulate drug use is, whether off label uses, whether experimental or not. this is a private company. they're not a very large private company. is there any ability to sort of merge with a public-private partnership there? technology and their model for making this with the rye sources of let's say a place like the cdc? >> yes, great question. and i think we have to keep in mind this is a little start up

company. it doesn't have a lot of this drug, even if these two people got better. it's not the case that we could rush a huge supply no matter who partnered with them overseas anytime soon. it's going to take awhile to gear up and make more of it. this is basically a private company that made it available to the people over in liberia. fda doesn't regulate what goes on in liberia. so to get things moving here you're going to have to have more money, either government or investors upping the ante, and you're probably going to start to have to involve fda and regulatory bodies even though it's working, even though this is a deadly disease. they're still going to want to keep an eye on it. >> all right. and we saw the pictures from sierra leone. it is heartbreaking to see. it's raised a couple of questions. just to quickly tick through a few of the things. can people catch this just from everyday contact with someone who has the virus? >> they can't. it's really tough to get it. you have to come in bodily

contact. you don't get pretty sneezing and coughing. it's not airborne so hard to get. >> the other thing thing we saw the tragic story or the woman who lost both her husband and son, yet she had ebola and she survived as well as her daughter. what determines who makes it through when you have such a high death rate, 90% of people do not survive it? >> i'm going to say three things. one, your general health. if you're younger and healthier, that's a plus. another is probably how much virus you get into your body in terms of how intimate contact you've had with someone who's had this disease. lastly, genetic luck. some people are going to have resistance more than others. we see that with the flu, we see it with tuberculosis. we even see it with aids, right? some people survive, very few, but they do. that's going to apply to these viruses, too. >> arthur kaplan, director of medical ethics at nyu medical school, thanks for giving us per respect i've today. now to continue this topic,

the world health organization says ebola has killed nearly 900 people just this year. but as you've both just alluded to, there are some stories of hope and survival. dr. tom karens is one of them. >> he was serving as a missionary in zaire, now the democratic republic of congo in the early 1970s and he contracted ebola. earlier, though, had he had a chance to speak with cnn about the pain and also the fear of dying. >> you know, the fever was certainly a big part of it. fever and flu normally doesn't drag on that long. and it carried on -- my wife made very good temperature charts. and this went on for well over a week into two weeks. and that would not be typical for flu. in addition, the rash that i developed, that would not be typical for flu. so we were realizing this was not a classical flu. there's something more to it than that. >> and how did he get it? cairns became infected when he

accidentally cut himself performing an autopsy at the hospital. >> you hear so much about it. it's terrifying to hear about the number of people who die, the percentages, very against you. but it's not airborne. you see the precautions worth taking anyway. no one even knew what ebola was at the time that he got it and survived. they actually treated him with aspirin, he said. >> wow. >> but he also said that he made it through, and that there is a lot of praying and he eventually recovered as we saw. >> fortunate for him he was able to pull through there. next here for you on cnn, caught in the crossfire. civilians in eastern ukraine are now hunkering down as intense fighting reaches their doorsteps. >> 20,000 russian troops massing on the border between russia an the ukraine. we're going to have much more on what is going on and the implications of that buildup in just a moment. hiring plumbers, carpenters and even piano tuners were just as simple? thanks to angie's list, now it is. start shopping online from a list of top-rated providers. visit angieslist.com today.

you owned your car for four you named it brad. you loved brad. and then you totaled him. you two had been through everything together. two boyfriends. three jobs. you're like "nothing can replace brad!" then liberty mutual calls. and you break into your happy dance. if you sign up for better car replacement, we'll pay for a car that's a model year newer with 15,000 fewer miles than your old one. see car insurance in a whole new light. liberty mutual insurance.

massed on the eastern ukraine border. that's a jump of about 8,000 rugz troops since last week. ukrainian forces are making steady gains around the city of donetsk. this is a stronghold for separatist russians in the ukraine. there is fears it could mean an impending ground war between the two groups. u.n. officials say close to 1400 people have died in the fighting in ukraine. that includes the troops, the fighters as well as civilians. hundreds of thousands of people have fled their homes. and emergency u.n. security council meeting on tuesday one official warneded that they were dealing with a growing humanitarian crisis there. >> an estimated 3.9 million people live in areas directly affected by violence. those remaining in the conflict zone face imminent security threats from fighting that is increasingly occurring in more densely populated urban areas.

fighting has caused significant damage to infrastructure, affecting the power and water supplies and access to basic services. >> a lot of civilians are also telling stories of being caught in the crossfire, close calls, brushes with death, and also as we've just heard him say, the lack of basic necessities. but nick patton walsh shows us that the biggest hardship of all for the civilians caught in the middle may be the fear of what might come next. >> reporter: almost doubled in a week, russian troops seen here in airborne exercises, flexing moscow's muscles last week near the ukrainian border now at 20,000 said one nato official up by 1,000. special forces, anti-aircraft artillery, armor, logistics. a lot that could seriously interfere in eastern ukraine. it is definitely quite here in central donetsk. but on the skyline visible there's been smoke. local residents and local officials saying there's been fighting out in one of the southwestern edges of the city

streets. level gun fire, fierce. but the ukraine military's advance to the city center has begun. no coincidence, perhaps, that now the ukrainian army is moving fast into donetsk. but inside the city on monday, great disquiet reigned. shelling has pushed some underground into cellars, half-built basements in this government building. where children and women eek out a life sleeping on mattresses they carry down here. twins who find the nightly explosions scary, loud. in this dim labyrinth they believe the separatists when they tell them the ukrainian army are american-backed fascists set on attacking the ethnic russians here. >> translator: they crush us. the damn americans, she says. what are they doing? where there is war in the world they have a part. look. these little ones here. they say they can't afford to leave, have nowhere to go.

>> translator: all the women of the world, raise your voice against these murderers. >> streets torn up. ukraine's army have used a lot of artillery in their first advance. and as she returns to her home for the first time, it's unclear who fired the shells here that shattered her windows. >> translator: if i'd been asleep here i would have died, she said. >> she was staying at her daughter's when the shells hit. here where shells landed, two people were killed. quiet, intimate lives flattened into blank faces of loss. they're burying their loved ones. the sense of the violence entering a final phase has no comfort when tragedy has already come and is member.

nick paton walsh, cnn, donetsk. >> we'll also speak with a retired colonel in the next few hours about what he thinks it means russia is amassing troops. later on cnn. first hawaii usually holiday destination and a tropical paradise. >> unfortunately that's not the case right now. they're bracing for two rude visitors. after the break we'll have the latest on a hurricane and a tropical storm headed right for hawaii.

firefighters are taking to the skies over sweden. they're trying to battle what's being called the country's biggest forest fire in modern times. hundreds of people have had to flee their homes. >> you can see some of the footage here. emergency workers say increased humidity and the lack of wind have helped them to encircle the fire. they say the danger isn't over yet. at least one person has been killed. hurricanes in hawaii pretty few and far between. in fact, the last time that a hurricane struck the islands was back in 1992.

>> however, as you might imagine this week you don't have one but potentially two storms threatening the island. our meteorologist joins us more with what to expect. >> can you imagine having your trip planned for this week and knowing historically it is usually the best place to be especially this time of year. typically don't see activity. 1992 as you heard there the last hurricane to make impact here. it was iniki. before that 1959 hurricane dot. only two hurricanes have impacted the island. iselle and julio. i want to show you the satellite perspective of iselle 24 hours ago when it was a peak intensity, category 4 sit in place. if you look at the symmetry, highly organized. all quadrants of the storm very impressive. only 4% of all hurricanes reaching this sort of status. typically they are slower to

weaken, they stay rather strong. this time around better news to report. the storm system has begun the weakening process because of two important factors. wind shear in place and the cooler waters as you approach the hawaiian islands. graveyard for the hurricanes here as they run into cool waters. begin to fall apart. important to note it is a category 2 storm system sitting in place with winds at 100 miles per hour or 60 kilometers per hour. the models take it right toward the islands there. emergency plans should now be really taking place here as far as having a seven-day kit in place. your businesses, your homes, if you can put up some boards for property damage. we know wave heights approaching the coast here could be upwards of 15 feet. of course, the surfers are going to be loving life but not the best time to be getting outside when you have 15-foot waves associated with the storm system. we are approaching a full moon as well. the high tide are going to be impacting that as well. that's iselle. if you look behind it, julio is sitting directly behind this storm system. the track of julio also going

right toward that direction. expect it to weaken to a strong tropical storm when it makes landfall. but still i've seen better weeks for traveling to hawaii than this one. >> hopefully people got their trip insurance, right? you never know. >> thanks, pedra. someone who didn't care about whether or not there was aim depending hurricane. two surfers joined this week by a special guest off the northern coast of england. >> a young seal crashed their surf session, climbed onto the boards. if i was a seal i'd do the same thing. caught the whole thing on a go pro camera. the seal reportedly hung out with them for nearly an hour. according to one of the men it was surfing like a pro. >> he video bombed their surfing. by the way for people that are wondering we had a lot of serious news but we were getting a small chuckle on the fact we did not do this on purpose. everybody is wearing some shade of sage green. it must be the full moon. >> thanks, kiran for being here. >> thanks for welcoming me here. had a blast. >> absolutely. come back anytime. more special coverage after this.

take 4 advil in a day or just 2 aleve for all day relief. honey, you did it! baby laughs! wouldn't it be great if hiring plumbers, carpenters shopping online is as easy as it gets. and even piano tuners were just as simple? thanks to angie's list, now it is. we've made hiring anyone from a handyman to a dog walker as simple as a few clicks. buy their services directly at angieslist.com no more calling around. no more hassles.

start shopping from a list of top-rated providers today. angie's list is revolutionizing local service again. visit angieslist.com today. add vanishing deductible from nationwide insurance and get $100 off for every year of safe driving. we put members first, join the nation. nationwide is on your side. welcome to special coverage on cnn. >> i'm feeling like the luckiest man on cnn tonight. big welcome to our viewers in the u.s. and