jesse jackson jr. facing ethics questions of his own. details on that tonight. also, in crime and punishment a home invasion that ended in the murder of a mom and her two daughters. the trial is ongoing and today new evidence and insight on an alleged motive. testimony so disturbing the sole survivor of the slain family had to leave the courtroom. and later sanjay gupta continuing his series on disease detectives. a gripping race to solve two life and death medical mysteries. a little girl's life hanging in the balance, so does a mom's. we'll show you how a team of disease detectives is racing to save their lives. we begin, though, tonight keeping them honest with a republican senate candidate dodging questions and a document congressman kind of doing the same. first, christine o'donnell, the republican senate candidate from delaware, continuing today to avoid questions. she announced last night she wouldn't be talking to the national media. she did that on a national forum sarah palin recommended she use, fox news. for days now, our reporter gary tuchman has been examining these old checks ms. o'donnell used to pay for what paerd to have been personal expenses. the problem is she appears to

have been using old campaign funds even though her campaign was over. if true, it would be a violation of federal election laws. now, ms. o'donnell denies any wrongdoing but has so far refused to answer specific questions about those checks. today at a campaign event reporters and their cameras were allowed in but couldn't ask any questions. o'donnell made clear she isn't happy with the coverage she's getting. >> it's wonderful to be here among so many friends. i'm glad the media is here, but i'm also a little bit disappointed because i wanted to talk candidly, and for some reason everything i'm saying is getting recorded and twisted. so i'm still going to talk openly with you. >> well, i don't speak for the media in general, but on this program we're not trying to twist anyone's words. we're simply trying to get some basic questions answered. these are questions which were first raised, actually, by o'donnell's own former campaign workers. kristen murray was the campaign manager for the 2008 senate campaign against then senator joe biden. she put out this robocall making very serious allegations against o'donnell. >> this is her third senate race

in five years. as o'donnell's manager, i found out that she was living on campaign donations, using them for rent and personal expenses, while leaving her workers unpaid and piling up thousands in debt. she wasn't concerned about conservative causes. o'donnell just wanted to make a buck. >> now a watchdog group is calling for an investigation by the u.s. attorney in delaware. christine o'donnell says they're a liberal group out to get her. >> so many people are excited about what's going on here and want to see us win. but so many people also want to see us fail. i'm sure you've heard the cnn reports that a george soros, very liberal left-wing group headed by melanie sloan has filed some trumped-up complaint against our campaign. these are the kind of distractions that they want to dominate the news to distract from our winning message. >> the group she's talking about is the citizens for responsibility and ethics in washington. they're called c.r.e.w., and they're partly funded by george soros and his open society

institute. they insist they're nonpartisan and they've gone after plenty of republicans as well as democrats. their director, melanie sloan, was on the program last night. >> c.r.e.w. is not a left-leaning group. c.r.e.w. takes all comers. we go after republicans, democrats, liberals, conservatives. we go after public officials and candidates who do the wrong thing. we're about right and wrong. not democrat, republican. >> funded by george soros? >> indeed, the open society institute, which gets its money from george soros, has indeed given us money. but if soros gives money to us because he thinks we only go after republicans, then i guess he's sadly disappointed by all of the actions we've taken on so many democrats, including eddie bernice johnson, who i've been on your show discussing, charlie rangel, maxine waters, and a whole host of others. >> so we asked melanie sloan a question, and she answered the question. that's more than we can get from christine o'donnell, something our reporter, gary tuchman, found out yet again today when he tried yet again to get in a question.

>> ms. o'donnell, we don't want to talk about personal issues, just about the serious financial allegations. is there anything specific you can tell us? we've given you a couple chances. >> talk to mitchell. >> reporter: we talked to your attorney -- >> we truly would like to hear ms. o'donnell's response to the claims and questions they've raised. we've invited her to come on the program every day since last wednesday. the invitation still stands. now the other candidate not answering questions is a sitting member of congress, a democrat. seven-term congressman jesse jackson jr., a chicago businessman has told federal investigators that representative jackson asked him to pay for airplane tickets for an alleged mistress, a social acquaintance, to make several trips between washington and chicago. this picture from the "chicago sun-times" shows the woman, a hostess in a d.c. restaurant. as far as our report tonight, the allegations of a mistress are frankly irrelevant, but trips paid for by someone else, if true, may be a violation of the house gift ban which limits gifts to $50. jackson did release a statement apologizing, but listen to what he was actually apologizing about.

he said, and i quote, "the reference to a social acquaintance is a private and personal matter between me and my wife that was handled some time ago. i ask you that respect our privacy. i know i have disappointed some supporters, and for that i'm deeply sorry, but i remain committed to serving my constituents and fighting on their behalf." you'll notice the statement doesn't say anything about the real allegations, did he ask this businessman to pay for trips and if so what did the businessman expect to get in return. all of this came up because of this guy, former illinois governor rod blagojevich. the man who told investigators about the alleged mistress is the same guy that told investigators that jesse jackson jr. tried raising millions in campaign funds for blagojevich, or at least said he would, so that blagojevich would appoint him to president obama's senate seat. jackson also denies that. joining me now, lynn sweet. washington bureau chief for the "chicago sun-times" and columnist for aol's politicsdaily.com. also senior legal analyst jeffrey toobin. so lynn, people are obviously open to interpretate the social acquaintance thing, but beyond

that, the ethical issue here, what is the biggest question? whether or not he actually asked these businessmen to pay for plane trips? >> right. anderson, the issue here is that congressmen are very specifically not supposed to solicit gifts. whether it's an airplane ticket or anything else. that is one of the most clear-cut rules that members of congress have. >> even if it's a gift for somebody else? >> right. because it still benefits you. you -- i could ask somebody to do something that might not be for me, but it's done at the request of a member of congress. that's a solicitation. that's whatnot they're supposed to do. >> what would it say about the congressman if in fact this is true, i mean, that he had this relationship with this businessman? it would be hard to imagine this would be the first time that this person was asked to do something like this, or clearly they must have had a close relationship if this businessman is telling the truth. >> well, the businessman has

been a fund-raiser for jesse jackson, he raised money for blagojevich. he raised money for other people in illinois politics. that, by the way, is common. people who are big donors and fund-raisers do it for a lot of people. what is very serious here, and what's new, is that up until now we -- our story at the "sun-times" was the first one that showed that there is some evidence that jesse jackson, jr., was involved in the conversation having to do that fundraising. this refutes statements he had made earlier that he didn't know that mr. nayak was out there raising money allegedly for blagojevich, allegedly in return for a senate seat appointment. >> jeff, in terms of legality, where does that stand? it's a minor thing, it's a couple of plane trips. is it serious? >> it's potentially serious. it's not the kind of thing that could get you expelled from congress, but certainly could generate an ethics committee investigation. the whole thing is embarrassing. the whole thing is inappropriate

if in fact -- and we have to remember, we don't know for sure this fellow's testimony is true. >> right. >> though jackson has not denied that its true. >> he has denied the blagojevich claim that he said he would try to raise $6 million. >> right. i mean, i think -- >> and if i might add, this man is under investigation, mr. nayak has his own problems with federal authorities, he's under investigation and he was a cooperating witness in the blagojevich case. >> which is all the more reason to view with some skepticism what he says. and i do think that this allegation that jackson offered to raise $6 million for blagojevich in return for the senate seat is kind of absurd on its face. jesse jackson can't snap his fingers and raise $6 million. he doesn't have $6 million. i don't think that is going to go anywhere. but the issue about buying the tickets for this woman, potentially a girlfriend, that very much fits within the definition of gift under the congressional rules, and it does seem to be a flat violation of

the congressional gift ban, particularly since he didn't report it. that could certainly generate an ethics committee investigation, a censure. mostly, though, i think it's a political embarrassment that will limit jesse jackson's political career at a time when the mayoralty of chicago is vacant and he's one of the people who's interested. >> lynn, do you think it would have an impact -- i mean, he's running for re-election in november. will it have an impact? >> i think it won't have an impact on his november 2nd re-election bid. his republican opponent has just a shoestring campaign. it's a heavy, heavy, heavy democratic district. this would be -- it would be hard to think that he wouldn't win in november 2nd. this might have an impact on other ambitions he might have for statewide or city office. >> do you think, though -- >> but by the way, he already was under some -- you know, he had some practical political problems anyway because of the whole blagojevich mess anyway. this just now compounds it. >> do you think it likely,

though, that the ethics committee would look into this, given the fact they're looking into charlie rangel, maxine waters and are i think probably sensitive about being accused of investigating african-american members of congress? >> i agree with you that as a practical political matter there is some rumblings that i heard that as what would have an outcome. but even before you got there, right now there had been the ethics committee, the committee on standards has already deferred any work on the jackson matter stemming from the original blagojevich mess because the justice department had its case pending. blagojevich's retrial happens in january, so as a practical matter, i would not expect anything soon because the committee still, which likes not to do anything most of the time, will probably be very happy waiting for this retrial to be over. >> all right. lynn sweet, appreciate it. and thanks for your reporting. thanks to jeff toobin as well. thank you very much. our political panel joins us ahead to talk about the gop's new pledge to america. it's going to be released

tomorrow. we have a copy tonight. it's basically a blueprint of how they say they'd govern if they take back the house. the tone is interesting. have they borrowed language from the tea party? we'll show you that. also you can join the live chat right now at ac360.com. ahead, disturbing testimony about these moments captured on a bank surveillance tape. the mom you see there, the woman, her two daughters were being held captive at home. she was later killed, so were her daughters. disturbing testimony in court today. new evidence about what the possible motives of the killers were. we'll have details on that. and later, a team of highly skilled disease detectives racing to save a little girl's life. can they solve the medical mystery? sanjay gupta reports. and will a grueling week of tests pay off for little kylie and her parents? >> maybe someday we'll get that phone call, hey, we think we might know what it is.ti ♪ an accidental touch can turn ordinary into something more. moments can change anytime -- just like that. and when they do men with erectile dysfunction

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so they can focus on serving their customers. i'm ahmed mady and i'm a homebuilder. my father brought me up to give back to society... felicia jackson promised her late sister that she would take care of her children. but she needed help. i used my american express open card to get half a million points to buy building materials to help build the jackson family a new home. well, i know if my dad was still around, he would have told me, with no doubt... he would have told me it's a no brainer and i knew that from the start. it was an honor. booming is moving forward by giving back.

well, if republicans take back the majority in the house in november's election, as they're expected to, they have a blueprint of how they're going to govern. tomorrow gop leaders are going to unveil what they are calling their pledge to america, a 21-page document that outlines their positions calling for a smaller government, rolling back the economic stimulus plan, and repealing the health care reform law.

cnn obtained a copy of it tonight. some of the language in it bears a resemblance to tea party rhetoric. one of the lines. "in a self-governing society the only bulwark against the power of the state is the consent of the governed and regarding the policies the current government the governed do not consent." it goes on to say, "an unchecked executive, a compliant legislature, and an an overreaching judiciary have combined to thwart the will of the people. like free peoples of the past our citizens refuse to accommodate a government that believes it can replace the will of the people with its own. we invite fellow citizens and patriots to join us in forming a new governing agenda for america." house democrats as you would expect have already denounced the plan as a pledge to wall street, corporate america, insurance companies and wealthy americans. let's talk about it now. eliot spitzer joins me, co-host of cnn's upcoming program "parker spitzer." kate zurnicki, national correspondent for the "new york times." also the author of "boiling mad: inside tea party america." and ralph reed, chairman of the faith and freedom coalition. he's also the author of the new book "the confirmation." ralph, is this basically tea

party language? >> i think there are three audiences. i was fortunate enough to be involved in the contract with america 16 years ago when you were both trying to energize the grassroots of the republican party, but you were also critically trying to talk to perot voters. we won that vote, by the way, 2-1. so i think there's three audiences. number one, the base of the party, and certainly among social conservatives there's a reaffirmation of marriage, of family, of the protection of innocent human life, of not having rogue judges who legislate from the bench. they're going to be happy with that. i think the second constituency is the tea party. and you alluded to some of that language in your opening. and the third audience, the most critical audience, in my opinion, is the disaffected independents. these are the ones who voted for barack obama overwhelmingly two years ago. today their job disapproval for him is in the high 50s. they're going to hold the key to this election, and by saying they're going to repeal obama care, they're going to extend the bush tax cuts, they're going

to restrain spending, they're talking to those independents. >> eliot, anything new in this? >> no. there's not only nothing new, this is the worst of herbert hoover and george bush. if this were actually implemented, it would take us back 50 years in terms of destruction of education, health care, infrastructure, our ability to compete. deficits would go through the roof. and the very people who created the crisis that we are living through even today would benefit once again. this is a sop to the very wall street banks, big businesses and the wealthy who benefited from george bush for a decade and now are back saying, president obama didn't solve it in 18 months. therefore, we want to go back and run the system again. it is one of the craziest, most outlandish fringe documents i've ever seen. when you really parse it, it is amazing, anderson. >> so having federal spending where it was in '08 is armageddon? >> invoking the 10th amendment -- ralph, when you look at what this really says and what it carves out and then what it says you will cut, what you are doing is destroying the

infrastructure of america, going back to the very broken, disproven policies of hoover and bush. >> i want ralph to respond, but kate, you wrote the book on the tea party. is the language taken from the tea party? >> absolutely. absolutely. the tea party has something called the contract from america which is a play on the contract with america. they say it's a contract from america, it's bottom up, it's what the tea party people want, it's what americans want. and they have this provision. they say there should be nothing -- every piece of legislation should say exactly where in the constitution it's authorized. this is something that tea party candidates like rand paul talk about. so this is very much tea party language. >> he's ahead by 15 points by the way. >> still -- >> we're going to impact -- >> no, we're not talking about political impacts. >> we cannot spend our way to prosperity. this is what glenn beck talks about on his chalkboard and we know how influential glenn beck is with the tea party movement. liberal keynesian economics. this is not a neutral document. the language is very charged. >> you've got $1.4 trillion deficit in a single year. you've got unemployment hovering near 10%. this economic policy is a

disaster. people are heading for the lifeboats, rahm emanuel's going back to chicago to run for mayor. they can't get off this sinking ship fast enough and you think it's a danger to the republic to say we should have laws consistent with the constitution? >> we had an experiment. we had eight years -- we had eight years of bill clrngs at the end of which we had surpluses, 23 million jobs created, and the middle class was doing well. eight years of george bush, an economic cataclysm the likes of which we haven't seen since the depression. exhibit a, exhibit b. this is going back to george bush and the broken policies that have been disproven over and over, and you're saying, gee, you didn't fix it in half a year, therefore your time is up. ralph, this is false -- >> eliot, i not only read the document, i talked to folks in the house before it was put together. this says spending should go back to where it was in '08. i don't remember the world falling apart at that level -- >> all the carveouts so that everything important will be -- >> and raising taxes in the deepest and longest recession in

the post-world war ii period is just not a smart thing to do, whether you're a keynesian or a conservative. >> but it's also interesting, as i say, when budget caps were used in the 1990s when a republican congress was able to bring a budget into balance and eventual surplus. i think bill clinton might remember that slightly different. remember the republicans shut down the government twice. i mean, this was not a republican congress-led effort. >> well, but there wasn't a balanced budget until there was a republican congress. the democrats didn't balance it. it was a fight -- >> ralph, here's the proposal i would make to you. would you say swap out the extension of the tax cuts for the very wealthy and use the revenue to reduce payroll tax, something that would actually generate job growth? if you had to choose between a payroll tax cut and extending the tax cut for the wealthy, which would you choose? >> i don't think you have to choose. i think it's an obvious choice. 43% of the income that you want to tax is small business income. >> that's simply not right. >> sub chapter s. i run a small business. >> so do we. >> i'm hoarding cash right now

and trying to stay alive. >> you should be hiring somebody. if you hired somebody, maybe we'd have a solution. which would you rather cut? >> but my taxes are getting ready to go up, eliot. that's the problem. >> this is what president bush passed. and we as fiscal conservatives who say we know about balancing budgets, say we need revenue to afford what we need to do -- >> eliot, you can't pass that proposal in a democratic senate. you're certainly not going to be able to do it -- >> you're talking about politics, not substance. let's keep to economics about what works. what bill clinton did was not popular when he did it, either, but it worked. 23 million jobs, a surplus. he understood economics and markets. >> that was after he signed the republican tax cuts. >> no. >> and the contract with america -- >> simply not the case. >> it was after he signed our budget and our tax cuts after he veto ee eed them twice that the economy went up and the dow went up and all that happened. >> the policies he put in place in the first two years, very difficult votes, that led to many people losing their careers. actual profiles in courage in the legislature in washington.

>> look at job growth. i was there, eliot. >> i was too. >> look at job growth from '93 to '95 and look at it from '95 to '99. >> can i talk about another issue here you? talk about fully funding missile defense. can you show us the evidence that it works after -- >> they've had successful tests. >> no, they have not. come on. let's get those documents released where it's worked once in a meaningful way. >> this document calls for two things the obama administration is not currently doing. it calls for strict enforcement against economic sanctions against iran, including prohibiting the foreign subsidiaries of u.s. corporations from doing any business with iran, and then it calls on obama to work with our allies to take decisive action to prevent iran from getting a nuclear weapon. >> and i see president bush was very successful with iran. >> you keep wanting to talk about bush. i hate to break the news to you, eliot -- >> no, no, no. >> -- but barack obama is the president. >> but what you're doing after a year and a half is saying time's up. he has dug us out of a hole, the deepest economic hole.

even your chart here, which shows what the job predictions were. without the stimulus, the unemployment rate would have been up to here. every economist understands that. >> i would highly recommend dropping george w. bush from your talking points. >> well -- >> and i think what ought to happen from now on is he owns this economy. he said if we passed the stimulus unemployment wouldn't go over 8%. >> we're not talking about polls -- >> it's approaching 10%. >> we're talking about actual data and how we will build an economy which requires investment in infrastructure, it requires investment in education. i agree with you when -- >> translation, more spending, higher taxes. >> no. not at all. we're going to cut the right taxes, the payroll tax, not the tax on the wealthy who don't either spend or invest at this point. >> no doubt we'll be talking about this a lot tomorrow as well. appreciate it. quick reminder -- >> we're friends, by the way. >> i know. we're going to go out in the hall later, i'm sure. don't miss "parker/spitzer" right here on cnn weeknights at p.

8:00 p.m. eastern starting monday october 4th. tonight in crime and punishment, the home invasion that ended in a triple murder. you've seen this video, mom withdrawing $15,000, desperately trying to save the lives of her two daughters and husband being held hostage in the home. she ended up dead along with their daughters. new information on what happened after she left the bank. and new details about the two men on trial for a crime that has shocked the nation. what police say one of the men said about the motive. and this woman's own muscles are growing wildly out of control. she doesn't work out, take steroids and no one seems to know what's causing it. can a team of disease detectives find the answer? >> it became increasingly difficult just to walk. at some point i knew if it continued it would kill me. the most powerful half-ton crew in america has a powertrain backed for 100,000 miles. chevy silverado half-ton a consumers digest best buy and the most dependable, longest-lasting full-size pickups on the road. now get 0% apr for 72 months on 2010 silverado half-ton models

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tonight, chilling new testimony in the home invasion robbery, sexual assaults and fire that left a connecticut mom and her two daughters dead. at one point today, things turned so graphic in the courtroom that the only survivor of the attack, the victims' husband and father, had to leave the courtroom. a police detective described his lengthy interrogation of this man, steven hayes, one of the two men facing charges that could bring the death penalty. we also learned details about this key moment when jennifer hawke-petit was forced to withdraw $15,000 from her bank account, her family being held hostage at the time at home. a moment that led to this 911 call by a bank teller. >> we have a lady who is in our bank right now, who says that her husband and children are

being held at their house. the people are in a car outside the bank. she's getting $15,000 to bring out to them. that if the police are told, they will kill her children and the husband. her name is jennifer petit, p-e-t-i-t. she lives at [ bleep ]. she says they are being very nice. they have their faces covered. she is petrified. >> randi kaye has new details from court today. in tonight's crime and punishment report. randi, we finally learned the alleged motive behind this just horrific crime. >> we sure did, anderson. chilling details. what we now know after years of waiting is that this crime may have taken place because one of the suspects, steven hayes, was "desperate for money." that's according to a connecticut police detective who interviewed hayes after the murders in july of 2007. the detective testified in court today that when he interviewed hayes after the suspects had been caught leaving the petit

home, he noted a "strong odor of gasoline" coming from hayes's body. remember, the home was allegedly set on fire by hayes and co-defendant joshua komisarjevsky. so it would make sense there could have been a gasoline odor on him. the detective also said, anderson, that hayes showed "no emotion" and he remembers him being pretty quiet. >> so the guy was desperate for money, that was their plan all along, just get money? >> it seems so. according to the testimony today, the two men devised a plan to "break into a house, tie some people up, grab some money and get out as fast as they can." well, we know that wasn't what happened in the end. we don't know all the details of course of what happened in that house, but we do know from police that jennifer hawke-petit was sexually assaulted and strangled. that was after the mother of two was captured on that bank security camera as she withdrew $15,000 to try and pay off the attackers and save her family. you can see how calm she is in that security video. well, that's because nobody at the home had been sexually assaulted before she had left

for the bank. she hoped it would be okay at that time. but by the time she did return home, police testified today, that the younger suspect, komisarjevsky-h already sexually assaulted the youngest daughter, 11-year-old michaela. she and her sister, 17-year-old hayley, were left to die in the fire allegedly set by the two suspects. another disturbing detail from court today, the detectives said hayes told him both men had a beer and a shot of liquor in a bar before they parked their van and walked up to the back of the petit family's house, anderson. >> so they came across dr. petit first. he was, what, asleep in the house downstairs? >> right. he was actually downstairs asleep on the couch and they saw him there. dr. petit, the only family member who survived this attack, was sleeping. according to the detective on the stand today, hayes told him that it was the other suspect who entered the house first through an unlocked basement door and beat dr. petit with a baseball bat in the head. they had found that bat in the basement. then hayes said he left him inside. he let him inside.

the detectives said hayes told him they searched for money but, "didn't find as much as they thought there should be." that's when the detectives said the two men went upstairs and tied mrs. hawke-petit and the girls to their beds. they allegedly put pillowcases over the children's heads. the detective said hayes told him that at some point "things got out of control" and that after he smelled smoke komisarjevsky, the other suspect, yelled that dr. petit had escaped and they needed to get out of that house. at that point police say, anderson, the men jumped in the family's suv and ended up crashing into police cruisers as they left. >> they confessed to the crime at some point, didn't they? >> they sure did. they were looking for a deal. both men tried to confess in exchange for life in prison. but prosecutors said uh-uh, no deal, and they are now pursuing the death penalty in this case. so as a result of that komisarjevsky's lawyer told us that the men chose not to confess in the end since there was no deal on the table. so they pleaded not guilty. >> i mean, it's such a stunning crime.

randi, appreciate the update. we're following a number of stories tonight. joe johns joins us with a "360" news and business bulletin. joe? hey, anderson. parts of the health care reform law go into effect tomorrow. today president obama met with some of those who say they're already being helped by that law. one new provision ensures coverage for children with preexisting conditions, but some insurers are responding by no longer offering policies just for kids. the owner of an egg supplier linked to the salmonella outbreak this summer is apologizing, telling a house subcommittee he is horrified eggs from his company might have gotten anyone sick. the mayor of bell, california, and seven other current and former city leaders arrested in a corruption probe made their first court appearance today. prosecutors say they misappropriated more than $5.5 million, including payment for meetings that never happened. bell's been in the spotlight after word leaked of sky-high city salaries.

and a dramatic end to a high-speed chase near miami today. police tipped the bumper of a stolen toyota camry, forcing it to spin out of control and crash into a parked car. one of the suspects tries to run for it and gets zapped with a taser. look at this. it's crazy. then another suspect was dragged along the ground and tased. and then they and a third man, all under arrest tonight. and that stuff, it looks like "miami vice" but it is actually really dangerous out on the streets, anderson, that kind of thing. >> yeah. still ahead, joe, new allegations against a prominent pastor who leads a flock of more than 25,000. a third man is now suing pastor eddie long-a cuesing him of sexually abusing him while he was a teenager. we have details and what pastor long is saying about the allegations tonight. also ahead, the parents of a sick little girl desperate for answers. dr. sanjay gupta following the disease detectives at the national institutes of health as they try to figure out what the

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tonight we pick up with the life and death stories of two very sick patients -- a little girl and a grown woman, both desperate for answers. they've come to a special program at the national institutes of health in maryland where teams of highly skilled disease detectives tackle the toughest medical mysteries around. cases that no one else has been able to solve. tonight their search for a diagnosis continues. "360" m.d. sanjay gupta joins us now. sanjay? >> i'll tell you, the pressure is intense now. because you've got to remember. kylie and sally have been to dozens of doctors. no one has been able to help them. kylie, she started developing tremors on the right side of her body. at first no one even believed her parents. >> right. first it was like a little twitch of her cheek. >> a twitch of her eye and her voice started changing a little bit. no one believed her parents. they literally were videotaping her. sally, her muscles started growing out of control. even the muscles around her eyes. i mean, she literally was starting to change the way she looked, and her whole body was changing. no one could figure this out.

so now we catch up with them just as they're undergoing a week of testing at this place called the udp. and i can tell you again, it's a very intense week. >> reporter: at 53 years old, sally massagee was physically ripped. >> everybody assumed i spent a whole lot of time in the gym. >> reporter: but sally didn't lift weights. in fact, whatever was causing her body to bulk up uncontrollably was also taking away her ability to live her life. >> it was very frustrating. i was losing the ability to do the things i loved to do. it became increasingly difficult just to walk. at some point i knew if it continued it would kill me. >> reporter: she'd seen countless medical specialists. no one had an explanation. that's why dr. william gallon and his team of world class specialists at the undiagnosed diseases program was trying to solve the mystery. this is super impressive.

i mean, you literally see a cleavage right in the middle of her back because those muscles are so big. >> dr. william gahl is the program's lead investigator. >> when you see these pictures, they are incredible. did you think steroids? >> sure. we pretty much all thought it, except the letter said she's not taking steroids, she's not taking anything anabolic, and she did weight lift a little bit but many years before. so there's no possible effect of that. so the endocrinologist had eliminated all the things we naturally would think about. >> when she falls asleep she tightens up some. >> reporter: dr. gahl and the udp see only the rarest cases. >> there's still a fair amount of rigidity. >> not only do they want to save lives, but they also want to advance science by identifying new diseases. >> bottom line, bone's not involved. it's not acromegaly. just confined to the muscle. what in the world could this be? >> reporter: during a week of intense tests, there are scans, blood work, an examination of everything going on inside sally's body. >> so this is sally's mri of the

brain. that's pretty incredible. >> when the images were found, it was seen that the muscles, even the muscles that govern the movements of the eye, which are really small muscles, are huge. the radiologist saw this and sort of went wild over this. look at the size of those, they're three to four times bigger. >> reporter: they probably really and truly had never seen anything quite like this. >> right. because there's no way to make those muscles big by like moving your eyes a lot. it's not like lifting weights. so why would they be that big? >> reporter: it's a clue. it suggests something inside the muscle itself. so the udp team took a sample. >> reporter: you took some muscle from her arm. >> right. and really this was one of those sort of judgment decisions, because she had had a muscle biopsy one year before that was read as normal. so we weren't like 99% sure we should do this. we were like 70%, 80% sure. >> reporter: in five days the

tests are complete. sally is sent home to north carolina, but no diagnosis. not yet. in fact, gall and his team treat their patients like a crime scene. they collect all the evidence they can find and then try to make sense of it. >> we do like the sort of detective work, but remember, a lot of the detective work takes place after the patients have gone. >> reporter: but that decision, to take the sample of muscle tissue from sally's bicep, in time, that will prove to be a key part of this puzzle. at midweek for 5-year-old kylie, her body has only given up a few small clues. but the specialists are eliminating possible causes by finding what is working normally. >> so this is the right side of her brain and this is the left side of her brain. it's the right side of her body that's affected so you would expect to see changes on the left side of her brain. >> i think things are structurally pretty normal, so

it's some sort of wiring problem that's not visible. >> reporter: an electroencephalogram, or eeg, shows kylie's brain is symmetrical, which is positive news. but there are these spikes of activity. >> very, very asymmetrical. >> reporter: it could point to epilessonly apartialis continua. that's a rare brain disorder that affects the brain's motor strip. however, that would only explain kylie's symptoms, not what's causing them. >> we're understanding the phenomena but we don't really have a full understanding of the underlying mechanisms that brought it on. >> yeah, this will help it not hurt. >> reporter: by friday the tests are complete. dr. gall and his team are planning what they're going to tell kylie's parents. waiting in another room, kylie's mom and dad are anxious, hopeful. >> they might have some things back from that, so it's exciting and i'm nervous. >> so we want to document that for her. >> reporter: but the doctors have no diagnosis. >> we're working all sorts of

things that have yet to come back for us to consider. >> reporter: instead they explain how the results will guide their investigation. >> we continue to work together on this. >> reporter: for kylie's mom and dad, gina and steven, the emotional toll of the week is just so overwhelming. >> we don't consider this to be a final diagnosis. >> the parents are really having sort of a tough time. and this is quite typical of this program. >> it was just i think too much for me at that exact moment, so. >> it scared me because i didn't want it to be the end. >> reporter: for the next several months, the udp team will chase every clue, hoping it leads them to a prime suspect. what is killing kylie and how to stop it. >> maybe some day we'll get that phone call. hey, we think we might know what it is. >> to go through that whole week

of that brutal test and then to leave not knowing, that's got to be just devastating. >> that's -- the way it is for most patients here, and that's sort of what doctors expect. but you're absolutely right, in that meeting, i think gina and steven, kylie's parents, were really fully expecting that they were going to get a diagnosis. to see their hopes so high and then to be dashed like that i think was really hard. but that is how it is. they're going to go through all these different pieces of data now to try and figure it out. and some of it might involve bringing kylie back, bringing her siblings back, the parents back to do more testing. that's sort of how it works. >> this is the third part of a four-part series so tomorrow night in the conclusion what do we see? >> tomorrow we get answers. obviously, this is something that's been transpiring over time. but we're going to finally come to the conclusion of what's happening with sally and with kylie and what doctors know so far. i want to remind you as well, anderson, that part of the goal of udp is to take care of patients -- >> udp is undiagnosed diseases program. >> undiagnosed diseases program. to take care of patients but also try and advance science. that's really one of the goals. give you a little bit of a look

at what's happening. >> reporter: in time, an analysis of kylie's dna revealed a genetic clue. they found a mutation in a particular gene that makes a protein called laforin. >> is it possible that what we're talking about in regard to kylie is something that's truly never been described before? >> it's very possible. >> brand new. >> brand new mutation and maybe identifying a gene that is -- is not known previously to cause a human disease. >> wow. >> we think in medicine that we have defined a lot of things, but there are things we're truly learning every single day and sometimes it's through these medical mysteries. >> well, that's tomorrow night on the program. look forward to it. sanjay, thanks. up next, a new approach to fast food, one that aims to help save the planet. ocid most calcium supplemts...

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when booked through ultimate rewards. fast food restaurants are no longer merely expected to be quick, they're also expected to be green. the websites for mcdonald's and burger king, kfc all tout various ways they're trying to be more environmentally conscious. a group in london and new york aren't just making it part of their meals, it's a main course. and it's one simple thing she's doing to help her planet, as becky anderson shows. ♪ >> reporter: this is not your typical fast food restaurant. instead of counting carbs, the diners at a oochlt tarian in london are counting carbon.

every item on the vegetarian menu has been chosen based upon its environmental sustainability. its carbon footprint calculated to include everything from how its ingredients are grown to how it's thrown away. and then compared to its fast food alternative. the savings are noted. >> thank you, you just saved an average of 2.8 kilograms of carbon, which is equivalent of driving 6.8 miles in an ecocar. >> reporter: it's an idea born out of necessity for lifelong vegetarian radica oswalt, aotarian's founder and ceo. >> if you're a serious vegetarian you would know some of the processing agents and additives used nowadays in those things are -- they fit no criteria of being vegetarian and sometimes no criteria of being an ingredient. >> reporter: and so oswal started researching what it would take to start up a chain of vegetarian fast food restaurants and found inspiration in sustainability. >> it's in our product, it's in

everything we do, it's in all our endeavors. >> reporter: endeavors that include the restaurant design. >> there are tables made of recycled plastic. the chairs are sustainable bamboo. >> reporter: the food packaging. >> we have 100% recyclable and compostable packaging range. even down to our soup lids and stickers. >> reporter: even the electricity. >> and we're also using green energy from suppliers who are producing green energy rather than those who just have the certificates for it. >> reporter: though some items in the restaurant may not be so green, sparking some criticism. aotarian, for instance, serves soft drinks. >> i guess it's part of providing customers a reason to come in as well, because we want to provide them a delicious meal, so having soda once in a while is not the end of the world. >> reporter: aotarian's green mission statement, perhaps an unusual undertaking for oswal, who's married to the billionaire behind berup fertilizers, owner

of one of the world's biggest liquid ammonia plants. a connection, while anything but organic, that oswal says is consistent with the restaurant's message. >> there's lots of people out there who, you know, have billions of dollars and they talk a lot, but they don't take it out of their pocket and put it in sustainability. i think we've put our money where our mouth is and that's doing our bit. besides, as far as fertilizers are concerned or the sensible use of fertilizers is an inherent process in conventional farming, without which it's not possible to feed the world. so it is a sustainability of farming. >> reporter: for oswal doing her bit involves just one simple thing, to make the world greener. >> the way we have calories nowadays in restaurants i also want footprinting. >> reporter: that's carbon footprinting. one fast food meal at a time. becky anderson, cnn, london. and that's it for "360." thanks for watching. larry king is next. larry king is next. i'll see you tonight.

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