from quality to flash from falsely to top this is where. welcome to the 77 percent. this week and all the t.w. . bacteria that are resistant to antibiotics have become a serious problem. in germany alone 35000 people are infected with these bacteria every year we're going to turn to it's a difficult situation it's getting worse. in the u.s. scientists are looking for solutions by studying medicinal plants used for centuries by indigenous people so. it's especially important to find new ways to treat infectious diseases today. in the caucasus republic of georgia doctors are

treating some of these infections without antibiotics. the fair a p in germany didn't work opiates. experts say that resistance to antibiotics represents a major threat to public health around the world. treatment programs in georgia have given some patients new hope echo heard a from maria traveled more than 3000 kilometers from their home in eastern germany to the georgian capital tbilisi. over the rule of law i was. desperate to find

a solution. and then i heard about these alternative therapy programs and peace from europe and georgia should serve them all strobel you both good ones where you go all good. hard is being treated at the alien office therapy center. he and his wife are accompanied by an interpreter. after eckart had heart surgery the surgical scars became infected with bacteria the infection spread to the membrane that surrounds the sternum or breastbone. he had numerous surgeries and antibiotic treatments to try to correct the problem but nothing worked. jailed or changed to the therapy in germany didn't work. i tried everything. during my last hospital stay in germany i came to the conclusion that the usual therapy for surgery and about x.

had no effect at all this those limits of the infections always came back quickly as they gave us a quote so that's why it was so too stoned to go before. the rule one doctor actually recommended removing the entire sternum list and most of the oh no i didn't like that idea at all so i started looking for alternatives. and i decided that this program in georgia might work and get all the room furnished with . cards and his medical records to the clinic in tbilisi the medical staff then told him that they could treat the infection with a process called phage therapy. and this involves the use of bacteria phages which are viruses that infect the bacteria and kill it. dr coca proceeds is preparing the 1st dose of phages. this sort of therapy is. not

approved in western europe just over your 5 years what i'm going to tell us in. a moment here at the beginning we use a very general type of faith and it. is it then we take a sample from the affected area and analyze it to see whether we need a more specialized type of phage that is that of itself then we can create those in our laboratory. side of tokyo for good. doctor who reads and now injects the pages into the area around the sternum. feed his or viruses that break into a bacterial cell and start reproducing this kills the cell then if age looks around for more bacteria to infect once all the bacteria in the problem area are destroyed the phages die. phages are also injected into the 2 surgical scars an echo hard suggest. this clinic is home to the world's largest phage bank.

your home in western germany is home to another couple who know firsthand about the problems of bacteria that are resistant to antibiotics sibylla i had foot surgery and the area around the incisions later became infected doctors could do nothing to treat the problem and eventually had to amputate her left leg below the knee. never lets the affection just wouldn't go away the doctors kept treating it with antibiotics but it didn't help i was running a fever the whole time and i finally asked them to remove the leg and. yet me on

a flight for almost 2 years she had extreme pain in her leg i was in and out of the hospital. i watched her go through. and then finally i realized that amputation was the only option left let's the. thought. that was 8 years ago. and in germany today alternative therapy for treating bacterial infections is still not allowed. sibylla says the situation makes no sense at all. is there any stairs up as it would be great if we had access to alternative treatment programs. and have our 6 i used way too often in just about every operation that's a huge problem isn't liza won't name. some bacteria have developed the mechanisms that protect them against the effects of antibiotics so the drugs kill only one resistant bacteria. and these super bacteria pose

a serious threat to public health not least because they multiply quickly. sibylla is all too familiar with this situation but she's grateful that she was able to recover successfully from her surgery and to get on with her life her pride is still intact and to stay physically fit she exercises a lot. that mean i don't want to walk with a limb thought it would make me feel like i'm handicapped and this is the quinta. but now she's dealing with a new medical problem she's been diagnosed with ask you arthritis in her right leg . sibylla who's 61 years old was deeply concerned about having another operation. lungful i've been putting it off for years but now that's no longer possible i'm getting in the uni and i'm really worried because of what happened the last time in

his surgery he had a lot of a funny dopey angst. she delayed the upper. because she was concerned about bacterial infection. bacteria food research is becoming more common in germany. sewage treatment plants provide scientists with a rich resource if ages and resistant bacteria they can test. dr christine awarded a microbiologist works at the lightness institute in the city of bronx fight. to says that this treated sewage may help them to understand better how features work. is open but for bacteria phages has viruses that can destroy specific pathogens. jamelia there are a lot of different kinds of bacteria in this move or bacteria phages are among the

world's most common organisms on hog hogs and what makes me leave them off the. road is current research is based on that of her colleagues in georgia she's trying to find 3 specific phages that could be used together to treat a dangerous kind of lung infection. the w.h.o. has a dell a 512 families of antibiotic resistant bacteria that pose a serious threat to human health. 3 are especially dangerous dr rohde has found phages that could control these bacteria. that's one of our the great thing about bacteria phages is that we know that they're effective based on the research of our colleagues in eastern europe. man who are always finding new faces and in the. e.u. requires that phages be subjected to various testing procedures just like new

medicines. yarmulke they're just therapy office some marvelous opportunities but we need clinical studies to prove that it's safe. defectives that's the word fix it doesn't work for. good it is working with dr holger tear from the phone hope for institute to produce features that can be officially classified as medicines. on the obviously this is how it's exciting thus far that's and this meets our goal is to demonstrate the pages should be considered vaccine did not want to take the procedures developed by our colleagues in georgia and develop features that can be officially approved as medicinal products here in europe and you know what parts of tablets it's about a matter of justice to be put us out we should have started this project 10 years ago and works harder to develop phage therapy because so many patients need it right now even at stanford about between. the 1st german phage drug is now being

tested at the sheraton a hospital in berlin. deep in the swamps of the southeastern u.s. state of georgia if no botanist cassandra quaver and her research team are also looking for alternatives to antibiotics. all right we're going to look for that c.z. alba which i believe is over in this area here they have the big black fruits on them in the bean family this is used as a treatment for wounds and and kind of cuts they would dig up their roots and make it a caution to rinse infected wounds so this one is of interest for us to collect so many shovels are in need the 1st vouchers the whole work up. the researchers wear leggings to protect against poisonous snakes. because sandra

is lower right leg was amputated when she was a child then she developed an infection caused by antibiotic resistant bacteria. that prompted her interest in this kind of research. you know she's studying indigenous peoples use of medicinal plants to fight bacterial infections. we should be able to try this in a couple of days or dryers. get ready for the lab. it's especially important to find new ways to treat infectious diseases today because we're facing a big crisis in medicine and that's the rise of you know by the resistance and i think that plants may be able to share some of the answers. the researchers have been working for 4 hours in hot weather and now it's time to wrap up for the day. the plant samples will be identified and catalogued. because sundra is doing all she can to prevent the spread of it about it resistant bacteria

for example she's found a way to fight bacteria that are often found in body in the gray areas of the brazilian pepper tree. each plant tissue this leaf actually contains hundreds if not thousands of unique molecules the fruits might have different chemicals plants make these compounds for their own defense. the big challenge now is figuring out which compounds are responsible for activity are they safe to use a can they be developed into the next generation of the right back to drugs. the plants are crushed and dried and then sent to a laboratory. no cassandra starts looking for the active elements that will contribute to her research. what we're trying to do with these kind of therapy is is to avoid direct killing of the microbes instead we're

disabling their ability to create toxins and other factors that destroy human tissues by doing that it is. sensually weakens the microbes to the point where our own immune system can wipe them out the goal here is not to eradicate all microbes in our on the body we need a lot of our microbes. it's a lot of hard work but the researchers believe the effort is worth it. meanwhile eko hard eisler has been at the clinic in tbilisi for 2 weeks in germany he had faced the prospect of surgeons removing his breastbone because of infection problems. know he's undergoing feed treatments 5 times a week. the material is injected into the affected area and is also administered to the 2 surgical scars that have not yet healed. how does

it look dr drew. the upper one is closed. the lower one is still open but the discharge of fluid has decreased significantly . for i used to feel a certain amount of tightness in my chest just right around the sternum. but it's gone down to it's. ok shin from the netherlands is also being treated here natasha hartmann suffered from a viral infection that turned even minor bruises into serious wounds the virus has spread throughout her body the clinic staff developed a batch of phages specifically designed to fight the infection. charbonneau costs less a settlement last summer a doctor told me that if i was lucky i might have 10 years to live if not i must

have just one year. back in holland they treated me with several kinds of antibiotics of a 14 years but it didn't help so i decided to come to this clinic. the treatments seem to be working and i hope that the wounds will heal by making progress i don't want to have to worry about dying i just want to get on with my life i'll song that's not my let's just got it's i want to finish it i leave. the patients pay for the therapy treatment plus the cost of travel and accommodations out of their own pocket the therapy alone cost $3900.00 euros. these people have one thing in common and infection treatments in their home countries didn't work. the therapies working right absolutely. it got hard also takes regular doses if it is in liquid form this distributes them throughout the bloodstream. the money will bleed if you take

a serious look at the problem of and i bow to resistance and it's clear that they have to try some new treatment methods with us. as for from the us what that means fate just like the ones they use here it is so big that the little. bacteria that can resist and of outtakes are spreading rapidly they've become a serious problem in hospitals. dr martin did some raw test to deal with this situation every day in his work at berlin's sherry tate hospital the bacteria can get into the respiratory tract of patients through medical equipment like ventilators. which it is in becomes

nothing for we have a real problem with multi resistant bacteria it's affecting our ability to treat some patients and we've even started using older supplies around to bionics and. we didn't do that for years because these medicines could cause serious side effects. at the same time a lot of the new drugs don't combat bacteria effectively so that's why we're looking into alternative therapy strategies and that is the sense of comfort. that in that you just i think that. the european medicines agency estimates that nazi resistant bacteria kill 25000 people in europe every year this issue ation represents a serious challenge for health care providers that's been ordered for i know who and for you go off and on and we'll be seeing higher medical costs more patients in the health care systems and a big increase in treatment programs. and that's when i can't say at this point how long i'll be able to keep this problem under control. but i think that over the

medium term perhaps in just a few years we'll have to deal with even more pathogens that we simply won't be able to treat. dr vincent wright and his team are conducting preliminary laboratory evaluations of faith based medicines developed by the likeness institute. the medicines are being tested on human lung tissue. into the bacteria phages are being used in some creeping programs in europe thus far off looks like you've seen a number of case studies that indicated they're effective. or to the best of my knowledge there have been no definitive tests on possible side effects. that's the if these medicines are to receive official approval for use with patients so we'll have to evaluate all the possible risks of the new ones so i.

know such studies have been done in georgia but doctors there used phages to treat patients anyway the e.u. however requires extensive tests. as a matter of minutes it's a race against time but we definitely need more evidence before we can put these medicines on the market are going to last for to suffer or to respond. well biofeedback technology is still being tested in germany it's actually being used in poland here at the hirschfeld institute in rights watch. there are turmel excited force there and her husband come run live in vienna they are to suffers from a chronic bladder infection caused by multi resistant germs only one at about it has proven effective in treating the problem. isn't

a fact that it's had we learned it is and we have no idea how long that mates and will continue to work. the bacteria could develop the resistance against it. fadden company but fates therapy can be used again and again until the bacteria are destroyed. i believe that this therapy will help me to live longer. and i need funding that are. still fade therapy is not widely available in poland. it can only be used if recommended by a doctor and only after standard therapy options have failed as in the autist case . the. surgeon is in charge of her treatment programs. is using phages developed specifically for this patient. he's been working with just for 13

years and says the therapy requires some patients. affect everyone differently. but in general we see the 1st improvements after 2 to 3 weeks of treatment. the full program usually lasts $4.00 to $6.00 weeks but of course every patient's immune system is different and so are the bacteria that we're dealing with. to look at folks. at this point dr treats only patients for whom all other kinds of treatment have failed in poland if ages can be used as experimental therapy. it says that phage therapy has saved the lives of several patients. we can successfully treat 40 to 60 percent of patients who suffer from infections

caused by resistant bacteria and cannot be effectively treated with antibiotics because. the fetus will be administered to the patient's bladder for 3 days in a row. the therapy program cost $650.00 euros. this is the artist's 3rd round of treatment after the 1st session she was free of symptoms for 14 weeks. hopefully my i'm still hoping for a full recovery came. garden ava maria eisler have now returned home to germany after 4 weeks at the clinic in georgia. if a maria administers the phage treatments and she sees some progress. or

like this the boston ones closed and it looks like the top one is tuesday now as that would be great it wasn't quite closed yesterday can you put a bit more on it. both ones on eco hard chest are now closed for the 1st time in months it looks like the phages have managed to destroy the bacteria. fat done. it to hard says his doctor has been following his progress closely. for it's why busy i went to see here 2 weeks ago she was quite pleased with the results of the phage therapy golden gun says it swiftly so she says it was a good idea for us to sign up for that program doesn't scoot for us with us enough time. echo hard who's now 73 years old it still takes a dose of phages in liquid form 3 times a day. she's

a nice little ta they don't cause as much trouble as and iyonix do. those drugs can destroy good bacteria in the intestines but these have few. side effects call i have no problems with us their appeal at all to go on the make. a card will have some tests soon to see whether the inflammation in the sternum has also cleared up but right now he feels great. my limbs florida. i'm definitely enjoying life again as well as the therapy is working harder than your mom but as i started noticing positive changes even while i was still at the clinic in ga festus even during the 1st week of treatment evil in the good of the storm but was so yes i'm enjoying life the no 2 lives photos god closer and. it does seem possible to treat bacterial infections by using bio fade just or

medicinal plants instead of that of iyonix they could provide a viable alternative as the threat of multi resistant bacteria continues to grow.

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plane. this is c w news live from berlin they political earthquake in turkey as the opposition wins control of istanbul 1000 celebrated the victory deals a humiliating blow to president branch uptight heir to juan and his ruling a party opposition candidate extreme in one of those tells the outcome as a vote for change does it also mean the beginning of the end for air to want. also coming up the rescue of 12 tie boys from the flooded cave 20.