iran's supreme leader ayatollah ali khamenei addressed himself to enemies within and outside his country today leading friday prayers for the 1st time since 2012 he lashed out at the united states and called for unity in the face of iran's enemies but with iranians protesting about the state of the economy and about the revolutionary guards fatal missile strike against a passenger plane that was carrying their countrymen how worried should the ayatollah big about next month's elections i'm filled and this is the day. that i will get off the plane crash was a better incident. burns through our hearts. before now i want to say that to the same extent that we are saddened and feel

grief in our hearts by this plane crash. our enemy was overjoyed much the same extent the. spokesman for the wicked government of america keep saying that we are standing with the arabian people who meet. these american clowns with their allies in their evil say that they stand by the iranian people they should see the crew the iranian people are. also coming up a multinational pharmaceutical company offers a 2000000 dollar drug to 100 patients for free but the recipients will be decided by lottery is that really ethical this is a game of hope often one happening outside the normal system would say so it's not how we should be doing things the tube system that. well iran's

supreme leader ayatollah ali khamenei has denounced donald trump's support for the iranian people as a pretense leading friday prayers for the 1st time in years he accuse the u.s. president of wanting to push a poisoned dagger into the country's chest they also described iran's strikes against the u.s. in retaliation for the killing of general solomon e. as a day of god. after weeks of national trauma thousands turned out to see iran's supreme leader in a rare show of strength the main cheered chanted as ali how many railed against iran's enemies. a spokesman for the wicked government of america keep saying that we are standing with the iranian people you are lying if you do stand with the iranian people it is because you want to stick your poisoned dagger into the chest of the iranian nation you haven't been able to do that so far

and you won't be able to do a damned thing. his intervention comes after the country's top military commander was killed by u.s. forces earlier this month triggering a nationwide outpouring of grief and a tragic stampede which saw scores killed then came what iran said was an accidental dining of a passenger jet killing all 176 people on board. angry protests engulfed the capital. yet the ayatollah lamented the crash but said iran was being manipulated lookin yippie some people follow the ana guided by american television some english radio try to portray this incident in such a way that the deaths of these 2 masses would be forgotten your mojo year.

i mean message hared loud and clear by president rouhani who sat among the washed. the ayatollahs presents underscores the crisis the last time he delivered friday prayers in 2012 amid a standoff over its nuclear weapons program in. hussein by night is an assistant professor at indiana university is the hamilton lucas school of global and international studies he specializes in iranian politics and u.s. iran relations and joins us from indianapolis welcome to day 8 of the let's start with that speech from the supreme leader what do you make of the fact that he led friday prayers today. well i think it's very significant obviously as the report stated it's very rare for the supreme leader to give to friday prayers only at crucial critical moments to the islamic republic does he

speak publicly in this fashion but i think it's important in that it clearly wanted to refocus the attention of the public once again on to the binary relationship between the united states and iran to make it clear that everything that is going on despite domestic mistakes and all the regional. hustle and bustle that's been going on that this is ultimately about the enmity against the united states and to really underlined up points that it is america is the enemy and that all should be forgiven and refocus on that point once again for taking a slightly cynical view how much of the killing of john general as solomonic reins retaliate iran's retaliate 3 strikes and a solid visible enemy like the u.s. how much of the helped to distract people from the country's economic woes. well i

don't think they have distracted as much as the regime would have hoped in fact i think they have underlined the depths of the problem long domestically in the minds of the public as we've seen in the case of the protests on the streets and in the last week or so in the aftermath of the handling of shooting down of the ukrainian airliner by iran's air defenses i think the regime is having up to a time trying to link these various different issues from each other i think to in the public mind increasingly these are sentiments of the same underlying problem which is the islamic republic's rigidity the rigidity of the power structure at depths of corruption and lack of transparency within iran's government and more importantly the fact that iran seems to be getting itself in tough geopolitical waters with the united states in a dangerous neighborhood so what's the game plan for

a full of this government and i just going to try and tough this out there are elections of course next month. yes i think that 1st or their business for them is to make sure that. this moment of crap all inmates in a unified government that divisions are not allowed to be brought up to the fore so the election results are going to be interesting to watch in that regard how government reacts what it is going to be some pretty engineering going on and i think in the longer term i think they are going to be waiting and see what happens in terms of the election process in the united states and do kind of buy their time and see what the next at in a stray ssion if there is an acceptance or action what possibilities would be over there but right now they're very much in a holding pattern and the 1st order of business is to consolidate and stratified the regime even more for the sort of let's look at this from from the other and that given the international pressure is now ranged against iran increased u.s.

sanctions the triggering of the nuclear deal dispute mechanism and of course the blowback from the shooting down of that ukrainian passenger jet. does that can erode does the international community need now to face iran with mall carrots rather than all the sticks. that's a very good question we're in a very difficult turn of iran isn't shipped with the international community i think the europeans would have hoped that iran has it within its technical under the j c p i it still is within that nuclear agreement but it has taken steps to move away from certain technical obligations it had it has put them in a difficult position and now they have to decide whether they are going to maybe rhetorically

back a harsher rhetoric against the regime as the united states has also maintaining some sort of diplomatic channel open so that iran doesn't become completely isolated and thereby. become a prop by the region for them. but that's a lot of that depends on how to iran was arms in the next 11 months or so before the u.s. elections here and whether its behavior is going to be something that is going to be maintained. by the outside world that as we will talk again thank you though for now inside adonai from the hamilton luga a school of global and international studies. efforts are established peace and security in libya moved to berlin this weekend as world leaders gather to try and find a path to peace for the north african country hosted by germany the presidents of russia and turkey will join senior u.s. officials and representatives of libya's warring factions on sunday libya has been

unstable since the 2011 civil war which saw the killing of the leader moammar gadhafi to rival governments of various militias with powerful international backus and i'm fighting for control whether they have been out of power. strongman general highly for have wants tripoli. together with his libyan national army he hopes to capture the country's capital and take full control of this oil rich nation. and it's partly because of oil that russia and turkey have waded in on either side of this conflict with turkey behind fires alsa raja's un backed government and russia supporting have to . moscow has denied reports it sent a messenger is to reinforce the general's fighters but on thursday turkey confirmed

it had started deploying troops to help in tripoli despite a un arms embargo. with libya's so on stable the fear of resurgent islamist terror has worried many european countries but other fact his mean the e.u. is split over it it's alliances officially the tripoli based government has the backing of europe including germany but italy has openly supported general hafta who it seizes crucial in stemming the flow of migrants across the mediterranean and fronts is concerns over terrorism as well as its interests in libya's oil wealth has pushed it id towards with the a use official line there are a claims it's given kovar military help to general hafta earlier this week peace talks in moscow brokedown despite the many interests at stake and the play

is involved germany seems determined to pursue you it's mediation role which even if a cease fire is agreed the road to peace looks new long and bumpy let's examine sort of those bums for professor in the tasha lynn stat there's a political scientists specializing in international relations as a particular interest in african i middle east politics joins us from the universe if ethics in england to welcome professor a kill we stop with a relatively simple question in this complicated picture is that room for compromise between these 2 sides and they have baucus or is it all or nothing it's going to be really difficult to find a compromise what i see is one of the biggest problems is that the un backed government doesn't really control that much territory so i don't see it as having much leverage where you have half to r. and his libyan national army controlling

a lot of territory and being supported by other actors in the region and outside the region including russia the u.a.e. and egypt and it's also received some support from france that there's this belief that have tar is best suited to fight against terrorists and to create stability in the region but he's not part of the national government and i think the concern is that he's going to want to play a huge role in what eventually becomes a libyan united government and that isn't going to work well with the u.n. backed regime which doesn't want him to play a big part in any kind of process of whatever of libya's independent state is going to turn into in the future so presumably that. territorial dominance is one of the reasons why he didn't side the peace accord that was how it out in moscow last week one wonders why germany things it can succeed on sunday

where turkey and russia failed. well i think they're just hoping they can get a ceasefire in the next that's the main objective is to get a cease fire and try to implement the arms embargo and then try to get a pledge from some of the extra nl actors to stop arming different militias or different sides and to stop using drones and that they can probably move forward after that with some kind of political process what they're hoping is just that initial 1st step of a cease fire because once you have a cease fire then that builds trust and then trust building is of course a key building block to to getting to some sort of. extensive peace deal but as you already mentioned the issue is happed are doesn't trust the other side doesn't trust the government of national accord and that was the reason you pulled out of the deal he didn't feel that there was a clear timeline in place for which some of the tripoli militias which he deems to

be terrorist groups would have time to disarm. so if you if sunday's conference did end with a cease fire who would police it. that's the big question that's a really important question and that's where we see some of the weakness of the u.n. framework and of the u.n. in general that it's not clear who is going to police and that's been the problem for libya as it emerged after you know decades of dictatorship from the beginning there was never any group that had a monopoly over the budget in the use of force and instead a multitude of militias emerged thousands even that no one could ever gain complete control over so even involvement from the international community didn't help matters we don't have one consensus over who is going to do that because there's already disagreement even within the european union you have france possibly sending arms to to have to our role italy is trying to psych with the u.n.

backed government so these are questions that are going to lead to a lot of disagreements because you also already have greece that is disagreeing with turkey's decision to create this maritime jurisdiction agreement with the with the libyan government ok so that they're over there's already squabbling before they even sit down so best guess then what do you expect to come out of sunday. well it if we try to look optimistic only there could be a temporary cease fire that happens and that why build trust as i mentioned before and we do our part is in hostilities which of course is incredibly important for civilians who have been facing a constant crisis since able we had a 146000 people that were forced to flee that's the best case scenario but i do you have to have a lot of power and

a lot of leverage she was able to walk away from the talks in moscow because they didn't suit him he knows that the u.a.e. and egypt are always going to back in the in willing to take on these types of rest and so my concern is that they may end up really with nothing but if we were to be optimistic best case scenario is that we see a pause in the fighting good talking to you thank you professor natasha lipstadt from the university of essex. a multinational pharmaceutical company novato sas and holmes that it will use i worldwide lottery to supply the world's most expensive drug to children suffer suffering from a devastating genetic disease but only 100 children who suffer from spinal muscular atrophy will receive the free treatment which usually costs millions the lottery on the drugs astronomical prices triggered an ethical debate. michael story sounds

like a modern fairy tale but it also poses questions he was born with spinal muscular atrophy a life threatening neuromuscular disease when his condition deteriorated despite treatment his family launched an online fund raising campaign aim for him to receive a gene therapy that's not licensed in europe the activity that he could. yeah the treatment cost almost 2000000 euros professional athletes and celebrities lead their support bowing to pressure from the public the health insurance company agreed to pay michael received the most expensive therapy in the world. that. grew thinner and there was a miracle that it worked at all then on the 3rd day we had another miracle under the he could turn himself over properly and in the 2nd week he even sat up on his own. the joint was shared by very many online supporters

but there are other opinions about the treatment some say not enough tests have been done to guarantee its safety more parents have been demanding access to it health authorities are sounding the alarm. this is about our promise so he'll weigh less and i really hope it's one that will be fulfilled but we still don't know if it will be and so this is a game of hope of one happening outside the normal system so it's not how we should be doing things system then the manufacturing of artists has issued a statement on its product the decision to implement the therapy must be made by specialized doctors under careful consideration of the risks on an individual basis and we are prepared to offer financial concessions to insurance companies. but this case highlights another major question in a public sector health care system how much may

a treatment cost many expensive gene therapies are set to gain market approval in the coming years what kind of results justify what kinds of costs at the university hospital in bonn dr young band meets families who have the prescription that costs 2000000 euros he says it doesn't make sense yet to start prescribing the therapy on a wider scale. i think if you wanted to do it with very new kinds of therapies where we're not sure how effective or safe they are we need consensus between all parties between specialist doctors experts centers insurance companies and licensing authorities only then can we properly decide which patients we should treat with a therapy that's at such an early stage and i'm that michael seems to be doing well so far although no one knows if the $2000000.00 euro medication has really healed his disease for good still his story shows how vital it is to regulate costly new gene therapies. well limited health care budgets expensive drugs and

sick children quite the mix dr to masa brune here is from bone university's institute for medical humanities oh welcome dr provine how can a drug treatment cost millions of euros. well you can't have them because there are a tense. company that has developed the drug as the right to a monopoly for so many years and so they set the price pretty much. in single sided some say but in a situation like that where where their treatment costs millions. who who is going to who could afford it is like you ok we have this drug but nobody can actually of 40 years it. that's a very good question. of course.

these can be seen as a part of an angle between producers the pharmaceutical company on the ones hand and on the other hand the consumers that are now of health care systems and health insurance company that will perhaps birches this this product and so they start with a very high price and there will be a negotiation over the price of what we will but there are people that are desperate for which. the drug is one of the few therapeutic option this drug could be curative so the definitive solution for for. the problem this form of spam her therapy and because it inserts a working gene into their cells through a viral back there and so you get functioning whereas before you had your us that

were not functioning so. it was a revolutionary treatment but it is expensive and it gives you hope even though it's hugely expensive but there's there's also the question of this a lottery which was apparently had housed in december without reference to doctors or medical or thor it is the idea that 100 lucky children are going to be picked in the last 3 other that does this sound ethical to you. my short answer is yes provided that the lottery is done well and then there is no way to divide the class of people the patients that are object of this lottery into groups of people that need the drug more or less in this case the problem is that it's very difficult for children under 2 year of age to have a problem noses and so to decide who are the people that need this most if i get it

well the supply is fixed of them on and there is only one production line so reason no possibility to increase the production immediately and so. as supplies kept. and so yeah a lottery needs self if it's not possible to sub divide the. the population of patients into a smaller sub classes can be seen as fair provided that it's carried out in a proper way of course it's ok let's ignore whatever ok let's look at the consumer add of this equation tell us about the that the process as well as national health system decides it is worth paying this much for one drug but not for another. these are gigantic problem. it's called in my attic is usually called the resource allocation and of course you have a health budget of certain amount of 1000000000. euros or us dollars or

whatever and you have to be assigned to spend it for the off needs of the population that can be in the case of germany. 80000000 and. of course there are tons of alpha needs tons of therapies what where do you put the money 1st i think it was nice we had yeah and there. were thank you for joining us dr thomas a brony from bonnie university. thank you for having. well the day is almost up to the conversation will continue online you can find us on twitter either x.d. w your has always been the followed me out fill over get yours a hotdog the day. of a good. strong

opinion clear positions of international perspectives. the middle east is once again being taken to the brink of war on the back and also because of trump against iran iran against trump but what about vladimir putin woman the old peacemaker to

find out join me in my guests on to the point fall for him to the point. next to. the goodness. up to date don't miss our highlights w. program online w. dot com highlights. we're going. rewriting the software of sample bacterial cells. we're not creating life growth we're rewriting the program for the software or read all over so all we can redesign them they'll have different properties i don't have a clue where we'll begin. changing the a b.

the last of the opposite approach would give us better occur from. just sort of using fossil fuel. to bake plaster. you could have organised sample sizes of all bills are right there are fake left we're just learning this is those who feel. the situation in the middle east remains explosive after tensions between the united states and iran took the region to the brink of war the what about the other big players such as russia when for instance german chancellor angela merkel wanted to talk about efforts to resolve the ongoing crisis in libya it was bloody putin in moscow that she turned to an old washington until not too long ago a waning force in the middle east russia is now one of the most influential voices

in this turbulence arena but of course it's both of policy to the conflict as in syria.