in the light of climate change in. africa. what's in store. for the future in the book. for the major cities to give insight. into. hello red welcome to in good shape coming up. autologous blood therapy how does it work. liquid biopsy a new tool for cancer diagnosis. and blood transfusions what are the risks. and.

endure host dr cost and the good shots. imagine me writing this bike 3 times around the world i would surely have to see a mechanic to get a few paired sometimes not so hot and this is the distance our blood travels around in our bodies have are old times because our optimism veins at a distance of more than 100000 kilometers and this is not all blood down as it helps us doctors to diagnose certain diseases sometimes even before a patient get symptoms. and that's why i'm here at berlin's that today this is where 65000000 lots and lots are examined every year the scientific director office all his english told he knows everything about not he will tell us how a few drops of it can tell us everything about all heart losers keep. not testing is an essential part of modern medicine.

discovering more and more it would tell your folks i was doing research that the study team in the loop on how to take cancer or even early stage heart who specifically target you. nowadays we are able to treat cancer patients individually with the help of the biopsies. for in sisters blood was like aspirin is for us today it was a cure for many things like behaving and blood against leprosy or drinking fresh schuman blood against seizures or just think about bloodletting to get rid of all the evil forces in the body well blood is not that creepy any war but it's amazing what blood can do. the heart continuously pumps blood around the body up to 10000 liters flow through its chambers every day enough to fill 50 bathtubs.

the largest archery is the aorta and it says thick as a garden hose while the tiny affinity than a human head. they form a kind of transport network. and blood is the body's delivery service it supplies the cells with everything they need like sugar ion fat oxygen and hormones . blood flows through the arteries at speeds of up to 2 meters a 2nd. and on its way back to the heart it brings waste products from the body cells like c o 2 and urea. and more than half the blood is made up of a plasma which is mostly water. some of the blood components are made inside the bones. they yellow mary contains he makes hope my attic tissues billions of new blood cells are produced every day

the different types of blood cells start off a stem cells through a process called cell differentiation they become white blood cells platelets and red blood cells. and they all have completely different jobs. blood platelets repair wounds white blood cells such the body for dangerous viruses bacteria and toxins certain white cells called plasma cells produce up to 2000 dandy bodies a 2nd they target foreign substances in the body known as antigens to neutralize or destroy them red blood cells contain hemoglobin which binds to oxygen this is how blood gets its red color the more oxygen it contains the brighter the red. blood is sometimes referred to as

a liquid organ which is no exaggeration considering the many vital functions it performs. i'm here with professor would have told by he's the scientific director of berlin left thanks for having me today it's more pleasant you're a left physicians and a blot specialist so what's so fascinating about plot well a lot is a peculiar fluids a very very complex mixture and it reflects like a mirror or a looking glass the condition of a patient both pursue respect to health and disease and we can find out a great lots of informations about the patient so are there any alarms sides that you can see in the blood before the patient even have stressed symptoms yes you address the matter of early diagnostics or what would even be

better of prevention in germany we take a chinese drop of blood from a newborn child and any law use it for markers of seaview diseases there are new methods in the. like mass spectrometry where do you use mass spectrometer for be used in a clinical lab is a quite new development and mass spectrometry allows the identification and detection even of molecules which have been to this state unknown of course when the patient takes a rock which has potential side effects it's essential to monitor the concentration. and since to date many new drugs are happily for the patients benefits introduced into therapy it's essential

that we in the lab able to detect and to quantitatively measure these new drugs and this is feasible by the use of mass spectrometry are there any tests that everyone should take essential tests include for instance cholesterol since color store is a real important risk factor for coronary heart disease 2nd i would recommend to do basic testing for liver diseases kidney model function i would have a white and red blood count and for female patients i recommend to enter law is the concentration the lot so if you don't want to see your g.p. there are some companies that offer blood tests over the internet what you think about this i personally have my serious reservations about not testing

over the counter without the it why is of a medical doctor or a general practitioner. the reason for this is that the tests we saw that must be interpreted and evaluated in this requires medical knowledge the interpretation of the sentence to link the test results with the personal history of the patient the medication the symptoms and other medical conditions and this is really important to come to the right conclusion based on the test result always see you drippy 1st except you know when the 1st blood transfusion was performed it was 1492 when the pope was sick so he needed fresh blood and he was given that from 3 young children unfortunately 3 children died and the pope didn't

get well the transfusions and now this is routine procedure in medicine but they're not that a danger. is about to have bypass surgery it's a procedure with a high risk of blood loss and the house is understandably worried. pretty frightened sure. it's standard practice to have blood reserves on hand during the procedure but the doctors here at the university in frankfurt are taking a different approach. of course it's a warning to us as major operations are a bit like running a marathon so we get the patients ready the way people prepare for a sporting challenge and it's so simple in terms of hemorrhaging hemoglobin plays a big role due to the higher the hemoglobin levels ahead of an operation the more of a buffer you have if they drop during surgery. that's the key factor in deciding if the patient needs a blood transfusion that's why the patient's blood is fortified with iron before

surgery and doctors establish if there's any likelihood of a coagulation disorder because a transfusion is always a risk. of blood transfusion introduces a range of foreign cells it's comparable to an organ transplant and house immunological consequences in fact. even a transfusion from the same blood group doesn't rule out a defensive reaction like fever hemorrhage or nausea. but we know that you can give a patient too much blood and overtaxed their circulation it could even cause a point so it's extremely important to be very careful and only give the patient the exact quantity they need. bookkeeper in addition it's better to err on the side of caution hospitals have developed patient blood management programs to prevent blood loss during and after surgery for example doctors can use what's called cell

salvage during an operation that's a way of collecting the blood lost during the procedure. it can then be infused back into patients if necessary. they are also kept warm with heated blanket it's. keeping the patient warm helps optimize blood coagulation so the patient loses less blood germ surgery something of that $36.00 degrees is the baseline temperature for blood platelet function platelets react to bleeding by clumping thereby initiating a blood clot. researchers at the university hospital in frankfurt have developed a small heart lung machine that helps limit blood loss after surgery lost can also be limited by taking smaller amounts of blood during tests. patient blood management programs can help hospitals cut blood transfusions by 50 percent. they also ensure the hospitals have sufficient reserves for patients such

as was left which we definitely will need donor blood. and was in this group we've noticed that your hemoglobin levels are on the low side to meet. him. she requires a transfusion after her hip operation for some patients it can be a lifesaver so every drop of blood matters. i'm still in burlap with professor talbot. black is also very important for the diagnosis of rare diseases can you give me some examples yes this example is for new kettle nuria it is east caused by this order of amino acid metabolism children affected by that is suffer from damage shows of the brain and suffer from mental retardation

if that easy is is diagnosed early enough that children can develop normally through a diet and all this can be diagnosed from a very small drop of blood. if there is something special about. it is that it's very closely connected to research can you leak some secrets what kind of research is going on yes. we are working quite hard. to improve and a little bit of wrong i lot spots this means a drop off but put onto a small paper card and try it and it will ask why we are doing that the reason for this is that it may be difficult to transport the creates

a lot samples in some areas geographical regions and it's much more easy to transport a dry plot spot on or caught in an envelope put into the mail a 2nd example is analytics and diagnostics to detect and to monitor or model function of kidney diseases or at kidney disease and here we develop new markus which allow and facilitate to properly estimate the degree of kidney malfunction many of my patients ask me if it's possible to detect cancer in the blood so is it possible well early detection of cancer in the blood is a real challenge. and with the exception of prostate specific antigen

p.s.a. to my personal view we have no screening chil marker which allows early detection of cancer. but there are prospects that we will be able to develop such tests based on genetic or and epi genetic testing and biochemical testing and possibly also based on liquid biopsy thanks so much for this interesting talk thank you it was my pleasure let's take a closer look on the test called the could see police to get some client you feel a little jam but you know that already. but a book so has come for a checkup so soon just 2 more and we're done. the blood test spares cancer patients a pain for a risky procedure to extract tissue from the tumor

a standard biopsy wasn't an option fruit or any way. when there is a person living under there in search all could positions in both the lungs but they're hard to reach and she hopes this liquid biopsy will help her switch to a targeted medication and come off chemotherapy which affects the entire body. i felt awful at the start the chemo wreaked havoc it really affected my blood values . the clinic that's treating belongs to a network of experts by testing their tumour d.n.a. in the blood samples they can often determine which subtype of cancer the patient might have targeted medications have been developed for certain types of the disease including. this one we might be able to give you medication in tablet form. but so far the medication has only been approved for ovarian cancer not for

a tumor and the long. one day an oncologist will treat pretty much every type of tumor regardless of whether it's breast cancer or ovarian cancer or something else the aim is to characterize tumor cells more and more precisely and to develop more drugs that allow us to move away from chemotherapy. that would be of great benefit to patients who would have less hair loss or other side effects all the problems you otherwise get don't happen when the therapy targets only the 2 marcels which helps patients quite a bit. has been having chemotherapy for 5 years now and she still has her ups and downs. so i have a lot of support from my family my husband my daughter my grandkids they always pull me back up when i feel. she's hoping the drug

will soon be approved for her cancer too so she can switch to this targeted medication. and gives dr claudia foible the bird in chile tea and you are performing the so-called liquid pipe see what thread currently modified aspects of star tissue so-called sections of piracies. this collection and i can be difficult and patients with poor general conditions like cancer patients and status and nowadays we have the option to do this analysis and others us off to more south genetic information on the cause biopsies so that means you're taking a blood sample of the patient and you're looking for d.n.a. of the tumor cells right we start with a collection of a little mound of a lot that we isolate the d.n.a. from the patient which contains the genetic information of the benign cells and also information of where cells what kind of information to gain from the spot

saying actually we're looking for resistance mutations that this means we're looking for changes in the genetic information of the tumor cell which lead to probably a progress of the tumor in the patient and so that we can change the therapy of the patient accordingly so does that mean that it helps you to find the right kind of repeat or just a just for you. it's a bit of both so actually we are of course hope that we can change the character of a patient in order to have a better chance for the patient and other any other advantages of a method one is that it is minimal and they sniffed so you can probably do a kind of money touring for the patients you can collect the blood. in serious and check if the resistance cures and you can do it many times before you see

a change in probably c t r n i t. right now you're performing this kind of examination of tumors so if you look into the future with other tumors you can do this examination you know this is a very promising and very valid so we expect to have this kind of analysis for breast cancer and very near future thanks so much for the interesting talk this is a very modern method doctors are doing with the patients blood but doctors have been taking that from patients for centuries and they're not just tweaking it they're giving it back to them. autologous one therapy is the treatment of disease by using a patient's own blind. to begin with i found it a bit spooky the idea of having my blood taken twice a week and then getting it reinjected over a fairly long period of time. long. but claudia hoff gave it a try she suffered from herpes for

a number of years and kept on getting the misters forming on her back at 1st she tried a conventional approach. as it was my dermatologist prescribed anti-viral drugs which i was supposed to take for 3 months. but fairly quickly after a few weeks it was obvious i wasn't tolerating it well. service is familiar with the problem antiviral drugs can be an effective treatment against her peace but he's also found that for some patients alternative treatments work better such as blunt therapy something he's researched himself at the hospital in berlin. says that it doesn't look at this is for cancer treatment that dates back to antiquity in the past it was seen as magic the significance of blood also played a role nowadays autologous blood terribly also called although he meant therapy is

used in alternative medicine as a stimulation therapy designed to alter modulating immune system. was a says i'm someone who's a show. it affects my whole body as a cup of elastic and i'm. cloudy off began the treatment in the spring to start with samples of blood were taken from a vein in her arm over a period of weeks. each time the blood that was removed was then immediately injected back into her gluteal muscle with a 2nd sterilized syringe with no additional processing. the whole blood their appeal involves gradually raising the dosage to 5 millimeters per session then reducing it again. how exactly does the therapy work. as i was. going to be fresh blood drawn from a patient's vein and re injected into their muscles triggers

a complex immune reaction that the details of this reaction have not yet been fully researched and understood but the reaction is triggered over and over we can boost it further by increasing the dosage which boosts the stimulus to. the cereal application gives rise to a sort of training effect that stimulation the immune system and thereby improving the body's immune competences it's also regulation. on this couple. studies appear to confirm the efficacy of autologous blunt therapy. given. it's a few studies have shown that it's effective in treating hives or to cardio. is good there's new research from a bomb for example that shows that therapy is also helpful with chronic fatigue. a clinical observation study at the shopping team has also shown that it's effective in treating her piece and the positive effect is still apparent

a year after the treatment that's encouraging news for cloudy heart. other forms of the treatment and follow some change to the blood before it has reinjected such as oxygenation ozone nation or the addition of homeopathic remedies designed to further stimulate the immune system as yet there are no scientific studies on this. during and after the antichrist blunt therapy cloudier hearts condition did improve a bit she gets here in lester's and they also clear up faster. i felt very good during the treatment. there was a positive experience much more so than i would have expected. that positive effect could be further boosted by a refresher round of treatment the treatment should always be done in a specialized practice hygene is of course essential.

fans in the meantime decided to go for a 2nd round of on thomas blood therapy. is what i can see there's been a change so i feel it was worth it in the end and there was nothing spooky about it at all. there's still no scientific proof that alter him with a repeat works so if you want to have a go with it 1st check with your g.p. like us g.p.'s always like your questions like i do. in good shape if you're a weekly health show on d w that covers many aspects of health care we look at what's new in medical treatment nutrition fitness and beauty we discuss these topics and depth with specialists and offer you opportunities to pose your own questions so get in touch . that's enough for today see what i freak and until then let's all try to stay a good check. politics

. keep learning reality wait a 2nd we want the whole picture our facts instead of make i.d.s. shifts to live us. from another reality to cryptocurrency your topics for live in an ever changing digital world let's talk digitalisation.

passengers here are informed by. drivers here need nerves of steel. while passengers here can get an eyeful along the way. taxis accommodate passengers over the work of. the driver coliseums. they were forced into a nameless mass. their bodies who are tools. the history of the slave trade is africa's history. this time something greed for power

and profit plummeted an entire continent into chaos and violence. and this is the journey back into the history of slavery. our documentary series slavery routes starts march 9th on t.w. . beethoven is for me. is for. beethoven as for help. beethoven is for her. beethoven is for the. beethoven is for us. the tovan is for the law for beethoven 2020 the 250th anniversary here on deal here.

this is to use a line from harsh words from germany's president for the world superpower. frank walter chooses the u.s. russia and china of stoking global mistrust and putting narrow national interests over international cooperation. and donald trump's long promised wall is taking.