well it's. his new world becoming less western and what does it mean for the world if the west leaves the stage to others the key questions at this year's munich security conference and join us for our coverage of him in the surety conference 2020 today on d w. hello wed welcome to in good shape coming up. on channel magus blood therapy how does that work. liquid biopsy a new tool for cancer diagnosis. and blood transfusions what are the risks.

and here's your host dr cost and they could tough to. imagine me writing this bike 3 times around the world i would surely have to see a mechanic to get a few paired sometimes not so hot and this is the distance our blood travels around in our bodies have are all times because our optimism veins have a distance of more than 100000 kilometers and this is not all blood down as it helps us doctors to diagnose certain diseases sometimes even before a patient gets symptoms. and that's why i'm here at berlin's that today this is where 65000000 lots and lots are examined every year the scientific director office all this cliff told us he knows everything about that he will tell us how few drops of it can tell us everything about all heart liver kidney. not testing is an essential part of modern. medicine. is covering

more and more of that tell your focus is doing research on t.v. lean on how to take cancer in an early stage specifically targeted. nowadays where you go to treat cancer patients with the help of the biopsy. or in sisters blood was like aspirin is for us today it was a cure for many things like behaving and lot against leprosy or drinking fresh schuman blood against seizures or just think about blocking it to get rid of all the evil forces in the body well blood is not that creepy any war but it's amazing what blood can do. the heart continuously pumps blood around the body up to 10000 liters flow through its chambers every day enough to fill 50 bathtubs.

the largest artery is the aorta and it says thick as a garden hose while the tiny capello offender than a human head. they form a kind of transport network. and blood is the body's delivery service it supplies the cells with everything they need like sugar ion fat oxygen and hormones . blood flows through the arteries at speeds of up to 2 meters a 2nd. and on its way back to the heart it brings waste products from the body's cells like c o 2 and urea. more than half the blood is made up of a plasma which is mostly water. some of the blood components are made inside the bone. they yellow marrow contains peanuts hope a attic tissue billions of new blood cells are produced every day

the different types of blood cells start off a stem cells through a process called cell differentiation they become white blood cells platelets and red blood cells and they all have completely different jobs. blood platelets repair wounds white blood cells search the body for dangerous viruses bacteria and toxins certain white cells called plasma cells produce up to 2003 bodies a 2nd they target foreign substances in the body known as antigens to neutralize or destroy them red blood cells contain hemoglobin which binds to oxygen this is how blood gets its red color the more oxygen it contains the brighter the red. blood is sometimes referred to as

a liquid organ which is no exaggeration considering the many vital functions it performs. i'm here with professor would have told by he's the scientific director of berlin lab thanks for having me today it's my pleasure you're a laugh ization and the blood specialist so what's so fascinating about blood well a lot is a peculiar fluids a very very complex mixture and it reflects like a mirror or a looking glass the condition of a patient both pursue respect to health and disease and we can find out a great lots of informations about the patient so are there any alarm sizes that you can see in the blood before the patient even have to see his sentence is you address the matter of early diagnostics or what would even be

better of prevention in germany we take a chinese drop of blood from a newborn child and any law use it for markers of seaview diseases there are new methods in the lab like aspect of the tree where do you use most bitterly to form. he used in a clinical lab is a quiet new development and mass spectrometry allows the identification and detection even of molecules which have been to this date unknown of course when the patient takes a rock which has potential side effects it's essential to monitor the concentration. and since to date many new drugs are happily for the patients benefits introduced into therapy it's essential

that we in the lab able to detect and to quantitatively measure these new drugs and this is feasible by the use of mass spectrometry are there any tests that everyone should take essential tests include for instance cholesterol since quest is. a real important risk factor for coronary heart disease 2nd i would recommend to do basic testing for liver diseases kidney model function i would have a white and red blood count and for female patients i recommend to enter largest the iron concentrations in the plot so if you don't want to see your g.p. there are some companies that offer blood tests over the internet what you think about this i personally have my serious reservations about not testing

over the counter without see it why is of a medical doctor or a general practitioner the reason for this is that the test result must be interpreted and evaluated and this requires medical knowledge the interpretation of the symptoms to link the test results with the personal history of the patient the medication the symptoms and other medical conditions and this is really important to come to the right conclusion based on the test result always see that repeat 1st except you know when the 1st blood transfusion was performed it was 1492 when the pope was sick so he did fresh blood and he was given that from 3 young children unfortunately 3 children died and the pope

didn't get well. transfusions and now it is routine procedure medicine but they're not without danger. of alamut is about to have bypass surgery it's a procedure with a high risk of blood loss and the high life is understandably worried. insurance of. it's standard practice to have blood reserves on hand during the procedure but the doctors here at the university in frankfurt taking a different approach. because of this major operations are a bit like running a marathon so we get the patients ready the way people prepare for a sporting challenge. in terms of hemorrhaging hemoglobin plays a big role due to the higher the hemoglobin levels ahead of an operation the more of a buffer you have if they drop during surgery. that's the key factor in deciding if the patient needs a blood transfusion that's why the patient's blood is fortified with iron before

surgery and doctors establish if there's any likelihood of a coagulation disorder because a transfusion is always a risk. of blood transfusion introduces a range of foreign cells it's comparable to an organ transplant and house immunological consequences fact that. even a transfusion from the same blood group doesn't rule out a defensive reaction like fever hemorrhage or nausea. but we know that you can give a patient too much blood and overtaxed their circulation it could even cause a problem an area deemer so it's extremely important to be very careful and only give the patient the exact quantity they need. to keep in addition it's better to err on the side of caution hospitals have developed patient blood management programs to prevent blood loss during and after surgery for example doctors can use

what's called cell salvage during an operation that's a way of collecting the blood lost during the procedure. it can then be infused back into patients if necessary. they are also kept warm with heated blanket it's. keeping the patient warm helps optimize blood coagulation so the patient loses less blood germ surgery something of that $36.00 degrees is the baseline temperature for blood platelet function platelets react to bleeding by clumping thereby initiating a blood clot. researchers at the university hospital in frankfurt have developed a small heart lung machine that helps limit blood loss after surgery lost can also be limited by taking smaller amounts of blood during tests. patient blood management programs can help hospitals cut blood transfusions by 50 percent. they also ensure the hospitals have sufficient reserves for patients such

as was left which we definitely will need donor blood. and was in the we've noticed that your hemoglobin levels are on the low side to meet. him. she requires a transfusion after her hip operation for some patients it can be a lifesaver so every drop of blood matters. i'm still in burlap with professor talbot. black is also very important for the diagnosis of rare diseases can you give me some examples yes this example is for a new kettle nuria it is east caused by this order of amino acid metabolism children affected by the disease suffer from them it shows of the brain and suffer from mental retardation

if that easy is is diagnosed early enough that children can develop normally through a diet and all this can be diagnosed from a very small drop of blood. if there is something special about. it is that it's very closely connected to research can you leak some secrets what kind of research is going on yes. we are working quite hard. to improve and the little effects of ra i blot spots this means a drop of blood put onto a small paper card and draw it and it will ask why we are doing that the reason for this is that it may be difficult to transport liquids plot

samples in some areas of graphical regions. and it's much more easy to transport a dry plot spot on a card in an envelope put into the mail the 2nd example is analytics and diagnostics to detect and to monitor or model function of kidney diseases or at kidney diseases and here we develop new markers which allow and facilitate to properly estimate the degree of kidney malfunction many of my patients ask me if it's possible to detect cancer in the blood so is it possible well early detection of cancer in the blood is a real challenge. and with the exception of prostate specific antigen

p.s.a. to my personal view we have no screening chil marker which allows early detection of cancer. but there are prospects that we will be able to develop such tests based on genetic or and epi genetic testing on bio chemical testing and possibly also based on liquid biopsy thanks so much for this interesting talk thank you it was my pleasure let's take a closer look on the test called liquid pipes policed. its client you feel a little jam but you know that already taken a special. book so has come for a checkup so soon just 2 more and we're done huge. the blood test spares cancer patients a pain for a risky procedure to extract tissue from the tumor

a standard biopsy wasn't an option for her anyway. isn't. there in such all quit positions in both the lungs but they're hard to reach. she hopes this liquid biopsy will help or switch to a targeted medication and come off chemotherapy which affects the entire body. at the start the chemo wreaked havoc really affected my blood values. the clinic that's treating belongs to a network of experts by testing their tumour d.n.a. in the blood samples they can often determine which subtype of cancer the patient might have targeted medications have been developed for certain types of the disease including. in this. we might be able to give you medication in tablet form. but so far the medication has only been approved for a very in cancer not for

a tumor in the lungs like. one day an oncologist will treat pretty much every type of tumor regardless of whether it's breast cancer or ovarian cancer or something else the aim is to characterize tumor cells more and more precisely and to develop more drugs that allow us to move away from chemotherapy. that would be of great benefit to patients who would have less hair loss or other side effects all the problems you otherwise get don't happen when the therapy targets only the 2 marcels which helps patients quite a bit. has been having chemotherapy for 5 years now and she still has her ups and downs. chuck i have a lot of support from my family my husband my daughter my grandkids they always pulled me back up when i was feeling low. milage mother and closed. she's hoping

the drug will soon be approved for her cancer too so she can switch to the targeted medication. gives dr claudia foible the bird in chile tea and you're performing the so-called liquid pipe see what thread currently guided asterix star on tissue so-called distractions of buyers sees. this collection and that can be difficult in patients with poor general conditions like cancer patients and status and nowadays we have the option to do this analysis that others us off to more south genetic information on because biopsies so that means you're taking a blood sample of the patient and you're looking for d.n.a. of that human right we start with the collection off a little mound of a lot that we isolate the d.n.a. of from the patient which contains the genetic information of the benign cells and also information off

a train yourself what kind of information do you gain from the spots in actually we're looking for resistance mutations so this means we're looking for changes in the genetic information of the 2 muscle which lead to probably a progress off the tumor in the patient and so that we can change the therapy of the patient accordingly so does that mean that it helps you to find the right kind of repeat or just a just for me it's a bit of both so actually yeah we are of course hope that we can change the pair of patients. in order to have a better chance for the patient and other any other advantages of this method one is that it is minimal and there is nothing so you can probably do a kind of money touring for the patients you can collect the blood. in serious and check if the resistance cures and you can do it many times before you see

a change in probably c t e r m i t. right now you're performing this kind of examination of tumors so if you look into the future with other tumors you can do this examination you know this is a very promising method and very valid so we expect to have this kind of analysis for breast cancer and very near future thanks so much for the interesting talk this is a very modern method doctors are doing with the patients blood but doctors have been taking that from patients for centuries and they're not just making it they're giving it back to the. autologous one therapy is the treatment of disease by using a patient's own blind. funds as miss him to begin with i found it a bit spooky the idea of having my blood taken twice a week and then getting it reinjected over a fairly long period of time. but claudia hoff gave it

a try she suffered from herpes for a number of years and kept on getting the misters forming on her back at 1st she tried a conventional approach. as. my dermatologist prescribed anti-viral drugs which i was supposed to take for 3 months. but fairly quickly after a few weeks it was obvious i wasn't tolerating it well. michelle answers is familiar with the problem antiviral drugs can be an effective treatment against her piece but he's also found that for some patients alternative treatments work better so just calling this blunt therapy something he's researched himself at the shop at a hospital in berlin. says that it doesn't look at this for cancer treatment that dates back to antiquity in the past it was seen as magic the significance of blood also played a role nowadays autologous blood terribly also called also him

a therapy is used in alternative medicine as a stimulation therapy designed to alter our modulating immune system. it affects my whole body and some cup of alaska. cloudy began the treatment in the spring to start with samples of blood were taken from a vein in her arm over a period of weeks. each time the blood that was removed was then immediately injected back into her gluteal muscle with a 2nd sterilized syringe with no additional processing. the whole blood therapy involves gradually raising the dosage to 5 millimeters per session then reducing it again. how exactly does the therapy work. because i mean news of. fresh blood drawn from

a patient's brain and reinjected into their muscles triggers a complex immune reaction that the details of this reaction have not yet been fully researched and understood but the reaction is triggered over and over we can boost it further by increasing the dosage which boosts the stimulus to. the cereal application gives rise to a sort of training effect that stimulation the immune system and thereby improving the body's immune competence it's also regulation but the one competence of this couple of assault studies appear to confirm the efficacy of autologous blunt therapy. given. it's a few studies have shown that it's effective in treating hives or to. there's new research from a bomb for example that shows that terribly is also helpful with chronic fatigue. a clinical observation study at the shocking taney has also shown that it's effective in treating her peace and the positive effect is still apparent

a year after the treatment that's encouraging news for claudia hoff. other forms of the treatment and follow some change to the blood before it is rejected such as oxygenation ozone nation or the addition of homeopathic remedies designed to further stimulate the immune system as yet there are no scientific studies on this. during and after the antichrist blunt therapy claudia hopes condition did improve a bit she gets blisters and they also clear up faster. i felt very good during the treatment. there was a positive experience much more so than i would have expected. that positive effect could be further boosted by a refresher round of treatment the treatment should always be done in a specialized practice hygene is of course essential.

cloudier half has in the meantime decided to go for a 2nd round of ontology one therapy. is what i can see there's been a change so i feel it was worth it in the end and there was nothing spooky about it at all. there's still no scientific proof that alter him with a repeat works so if you want to have a go with it 1st check with your g.p. like us g.p.'s always like your questions like i do. in good shape your weekly health show on d w that covers many aspects of health care we look at what's new in medical treatment nutrition fitness and beauty we discuss these topics and depth with specialists and offer you opportunities to pose your own questions so get in touch . that's enough for today. and until then let's all try to stay it good check. the bill.

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