slavery routs starts march 9th on d w. the below. this is d w news live from berlin a plea from the w.h.o. as global coronavirus cases topped 100000. this is an old. to do is use an old the time to give up. this is not a time low for excuses. this is a time for the pulling out all the stops. the head of the world health organization

implore his government to ramp up there were sponsor covert 19 researchers have been racing to develop a vaccine for the virus but it may take longer than toll. and thousands of migrants and refugees stranded between turkey and tear down their hopes of crossing to europe are dashed as greek border guards make a fresh show. i'm sorry so misconducts good to have you with us the head of the world health organization has warned that many countries are not acting aggressively enough to contain the spread of the corona virus now as the number of global cases rises past 100 allows a doctor to draw skipper a yes this has warned that governments around the world need to bring all of their resources to bear in order to slow the spread of the cottage and he also said he is especially concerned that covert $1000.00 is spreading to countries with weaker

house systems where it may be more difficult to contain the outbreak researchers around the world have been racing to develop a coronavirus vaccine but how close are they to success here's a look now at just how vaccines work. the most effective way to prevent specific infections is to harness the body's own immune system that scenes like those used to prevent flu are made from either a weakened version of a virus or pieces of its genetic code the vaccination puts the immune system on the alert it makes antibodies that help it respond quickly to the target virus if exposure occurs under ordinary circumstances it can take up to 5 years to develop a safe and effective vaccine but in a race against the novel coronavirus some labs have already begun testing candidates in animal models sounds promising does that mean we'll be seeing one in the next few months that's been implied. we're talking about a vaccine and they're moving along very quickly all of the pharmaceutical companies

are moving along very quickly but in vaccine development experts say quickly is relative if everything moves as quickly as possible the soonest that it could possibly be. a half to 2 years that still might be very optimistic in the meantime could antiviral drugs and at treating those who are already infected help the development curve for a new medicine is even steeper than for a vaccine that can easily take 10 years for a new pharmaceutical to gain regulatory approval and the industry claims it costs upwards of a 1000000000 euros around 9 out of 10 drug candidates never go into production they fail at some point during testing but there's also hope that some medicines that were originally developed to fight other diseases could be repurposed like a compound called rem does appear it was originally planned as a treatment for ebola and was tested when

a major epidemic had west africa back in 2013 though it didn't prove very effective against that disease the company says it does affect corona viruses and hence could help covert 19 patients disease experts say repurposed drugs originally developed to fight malaria or hiv also show promise clinical trials with all these compounds are ongoing. let's talk about all those efforts with derrick williams from get up the science issue with us here in studio hi derek we were already hearing about vaccine development when the outbreak 1st became really known in january and now we're hearing that this could take at least another year before a vaccine is developed why the delay well i mean what originally the a lot of the groundwork was already done for looking into vaccines for coronaviruses due to the outbreak of sars and mers which are related coronaviruses so there was a fundamental sort of basis of knowledge there we weren't starting from scratch

we're starting from 0 but the candidates could be could be put forward very quickly but a candidate is just that it's a candidate that still has to drop to go through a lot of regulatory hoops before it can be declared both safe and efficacious so the 1st the 1st hit that it has to go through is the animal testing and and you can't just tested in any animals because you need an animal that's going to react to the virus in the same way hopefully that a human would so to get results that are robust and so they're searching right now for the right animals to test that that's in what's called the preclinical phase let later will come the phase where they begin to take a test in humans to see whether or not a vaccine could be is actually safe and then they'll start testing this if they can see this effect of nest but that you know that can it shows you a little bit and at the end of all of that process once you have something that's both safe and effective you still have to ramp up production on it so that's why it's even talking about timelines of

a year to 2 years it's very ambitious what about other medicines existing medicines that are being called into question as a possible use here possible treatment how can it be that a medicine that was developed to treat ebola could possibly be repurposed to treat covered $1000.00 what's interesting here is the word we're desperately seeking for treatments as quickly as possible and so one of the 1st stops that they that they're going to take is going to be looking at medications that have jumped through most of those. regulatory hoops already or maybe all of them and they're hoping to get to strike it lucky now now rim does appear which is this which is one of the leading candidates that they're testing right now in china it didn't prove to be all that effective against ebola out in the field which was it was initially developed for but then they later discovered that it does show some activity against the both the stars and the mers virus now now the way that it does it's effective in the sense that it seems to to hinder replication of the virus now but the replication of the virus is a very fundamental evolutionary information that tends to remain intact across

species it's kind of basic evolutionary information so they have high hopes that by affecting this activity in stores and mirrors that the qur'an the novel coronavirus that causes coven 1000 that it will do the same thing in that virus but the jury's still out ok so how are people who have been infected with of an idea how are they now being treated in the hospital when most of the people who are have have contracted serious cases of it they require hospitalization or they are elderly people who have what are called co-morbidities they have conditions like diabetes or existing respiratory conditions already and and those are the people who are who are tending to end up in the hospital because there is no existing medication for treating them or none that's been approved yet they're being treated in the same way that that they would be treated if they came down for example with a very serious case of the flu there it's they're focusing on fluid intake on pain relievers and they're using you know in worst case scenarios and breathing

apparatuses to help them to help them breathe but i think it's really important to say we can't state often enough that 4 out of 5 of these cases to the best of our knowledge are mild enough that they don't require hospitalization and so people should be beat not be worried as much about that and remember that that once they've had it at least theoretically their immune system will have wiped it out and will also provide them with some kind of immunity at least theoretically for a while right derek williams from d.w. science thank you so much. now a human rights monitor says 15 people have been killed in clashes between syrian government forces and rebel fighters in southern italy this despite a tentative cease fire that went into effect at midnight now the cease fire is the result of talks between turkish president but attacker to want to end his russian counterpart vladimir putin their meeting in moscow was aimed at diffusing the

increasingly volatile situation in the region and avoiding a direct confrontation between turkey and russia. after 6 hours of talks and a one and putin stepped out in front of the cameras to announce a security corridor or joint patrols and the all important cease fire. the 2 leaders have looked tense as the negotiations began the complex and long running conflict in syria has put turkey and russia on opposing sides but now they say they are committed to deescalation what. we hope this agreement will lay a foundation for the suspension the fighting in libya. we hope to end the suffering of civilians there and to avoid a greater humanitarian crisis. you don't know when they see. the northern syrian province of idlib is the last stronghold of anti-government rebels. with deadly air strikes happening almost every day in recent months syrian troops

have been fighting rebels with support from russia. but the rebels are backed by turkish soldiers the latest cease fire deal establishes a security corridor on each side of it live strategic east west m 4 highway join turkish and russian patrols will begin on march 15th. speaking on russian television shortly after the deal was announced syrian president bashar assad played up his ties with moscow. he says by turkish aggression a common goal of russia remains to make turkey change its policy away from supporting terrorists and to bring our relations back to normal. with thousands displaced by the fighting the international community led by the e.u. is focusing on alleviating what's already a humanitarian catastrophe and earlier ceasefire deal for it live quickly fell

apart as turkey and russia accused each other of not sticking to the agreement the world is now waiting to see whether it's that pattern will repeat itself well foreign ministers have been meeting in croatia to discuss the situation in it live and that agreement between russia and turkey. is in zagreb following that ministers summit for us good to see you what do the ministers have to say about this cease fire agreement. ministers here in zagreb welcomed the initiative they welcomed it in the sense that it is a sustainable initiative in this shift that will provide a ceasefire or a truce that will allow aids to get to the people who need it the foreign policy chief burrell today made clear here what we're looking at and that is $100.00 trucks per day leaving from turkey into the mountainous region of syria

delivering 8 to over a 1000000 internally displaced people there and the e.u.'s put a lot of money on the table but they do want to see that this money gets to the people who need it and so if the cease fire holds good news here in zagreb care what about the people who have been displaced now and are living in turkey and in turkey wants the european union to offer more political and financial support for hosting refugees what have ministers said about that well you're provide more support. well the german foreign minister eichel mahseer today made very clear that the e.u. and chirk you have made a deal regarding refugees and that deal is currently violated by turkey whereas the e.u. still intends to pay a full 1000000000 euros in financial aid to aid organizations in turkey to help the refugees and to help with the burden but it is turkey at the moment that has basically opened the border and it struck

a message sure it took the foreign policy chief corel today to say to refugees type directly address refugees in turkey to tell them no the e.u. border is not open so ministers who were very clear they do not want to be blackmailed and there will be no direct extra money on top of that 1000000000 euro that is already there to help aid organizations in turkey. all right. reporting there for us from zagreb thank you very much for that update well tensions between greece and turkey on their shared border are rising and leaving thousands of migrants and refugees stranded between the 2 countries greek border guards are doing all they can to stop people from entering and on the other side of the border turkey is also deploying tear gas if you don't deploy in $1000.00 extra special forces along the border to stop the migrants from returning there did any of correspondent yulia han sent us this assessment. the situation here at. the border

crossing with greece remains tens of thousands of refugees and migrants are still there demanding to be allowed into the european union now turkish believe how banned journalists from entering the area which makes it very difficult for us reporters in the pen the verify what happens along the border what we do know is that tear gas was fired again this morning by greek border guards and. now each side is blaming the other for the escalation so right now it seems very much on clear what will happen to the people holding out there many of them have been here for a week. well as you mentioned their reporters are blocked from entering the no man's land between greece and turkey which is why we've had no images of conditions there in recent days but has received this exclusive footage filmed by migrants in and around the zone between the 2 borders and it shows some of the thousands of people

stranded there they left open its border a week ago to allow refugees to make their way to greece but the greek border remains officially closed to them. all right coming up next business africa with ben physical and he'll be looking at how the corona virus outbreak has dealt a blow to south africa's already struggling economy thank you for watching. football for the rich and home of the fortune. dragons. books or news.