a look at the montrose alex shines its reputation. 60. light years is on its way to bring you more conservation. how do we make cities scream how can we protect habitats we can make a difference global ideals environmental series again global on g.w. and on mine. hello and welcome to in good shape it's summer time in berlin but today's show is not about ice cream it's about cancer but don't be afraid. and

always deadly life will. be in good shape meats and so long unfair on hogs learmonth and so i was just 30 but he's already been fighting cancer for 16 years. is his doctor put the sherry to university hospital in berlin. i'm oppressed holds nice young patients managed to interpret such a terrible diagnosis by cancer into the lives and to leave a quite normal life. when you are young they are a lot of things in your agenda your 1st love your 1st job and your very 1st own apartment but when you're diagnosed with cancer everything's on hold your whole life needs to be reorganized. finished fast that's close to the worst part for me was not knowing if. this will stop this cancer by the end that if i was gay. to get as old as i thought i would. and we as

a concern was some how long will it take the lying about us council on one bed when i lightly able to lead a normal life again and put it behind me when will i be able to forget it and write that my desk up. over a 1000000 young adults develop cancer every year at 13 it's 26 years old in 2018 a gene mutation caused her to develop breast cancer she was making plans for her future then suddenly she was dealing with surgery treatment and fear. when to pay cast compliment i thought if i'm unlucky i'll never be healthy again i'm deaf i'm unlucky all dying before i get my college degree before i can become a teacher before i can have a family and i didn't want that so i said to myself i have to do everything possible to make sure that doesn't happen that's the. catarina had been looking

forward to qualifying as a teacher and starting work but it wasn't school that she went to every day it was the clinic. found finished it was an incredibly dramatic experience for me being so happy that i could finally start my teaching internship i was so close to finally being able to start my dream job but then cancer got in the way. deanna listener knows the problems that young cancer patients face the oncologist at berlin's sharia to a hospital also works for the german foundation for young adults with cancer the organization helps those affected and is committed to helping raise public awareness. we have to take into account fertility issues we also have to factor in that young patients might not stick to the treatment program because they simply don't want to go to the clinic every 3 weeks . we have to keep explaining to them that they need to follow the treatment

schedule which has to be very strict. something that presents a big challenge for the medical team as well. you know also suffers from a metabolic disorder which forces her to keep her arms and legs covered but she's determined not to be defeated she's also helped by her work at the foundation for young adults with cancer. gives me so much. on the one hand thanks to be exchange with other patients. that's what i've had and also just because we have a lot of fun together we don't feel that cancer dominates our lives. i think we can get together and laugh about it. while the whole can. mean a chose to have both breasts removed she underwent chemotherapy and hormonal therapy that induced many of us but give us with a. kind of these effects in my case the men who pulls resulted in

a complete loss of libido. but i just think it has a very negative effect on your sexuality there is just so many side effects that can mess it up look at this i was lucky that my boyfriend stuck with me but as a young person as a young couple you want to be able to enjoy life and love and not just doesn't work nothing works. catarina would like to have children but the treatment can damage the ovaries she's had her eggs frozen to use later in spite of the uncertainty she hasn't lost her love of life the tumor is gone she's going to teach and she's making plans even though she knows the cancer could come back for me i feel that i've become much stronger in many ways. i somehow feel my growing up even though i've been thrown back a few steps in a way i'm a bit like a child again because i need people's help. but ultimately i feel moment you're

stronger and i know that there are more important things in life than over little things that used to get me upset me thinking and didn't get so much to kind of kind of understand after like that i'm going to the end i meet the burden share the t. hi thanks for meeting me today and you're a cancer patient actually so you develop cancer when you have 14 years olds and dr no you are 13 and you still have liver cancer so how do you feel today they were really great actually so i'm not like. thinking about to watch every day it's want. kamandi every minute or demanding every minute every 2nd of my day i mean aware of a lot of the disease and i'm coping with it it's not like it's. it's controlling my life it's not controlling your life i mean it's more than half of your life it should be at 60 years you're a cancer patient so hall how was it for the 1st time the doctors were telling your

the diagnosis. actually it was because between the diagnosis or the. suspicion for the 1st the 1st signs that half the cancer in the liver and the 1st surgery there was about 2 days so it was really fast and even after the surgery because of the subject of the surgeon come come can come to me and said it went well we got everything out so and then it was like all right that that states that we have to know what to talk about again and like after 2 or $34.00 days they came to me came to me again and they said we have found. in lymph nodes and. self's this is devastating i mean this is disappointing to get you think you were cured and then they told you that the disease is still going and then this was not the only time you realized that this disease was ongoing that it

was part of all the years that yes it has so on like in total. 666 times. $6.00 to $6.00 times including the original one and. yeah it was like. there was the easier ones that got me got that got to take i got taking all that with me massage really took like 2 hours and was done and then there was there was a long there was like 2 surgeries where the surgeon came to me. before the surgery . we try our best and we if we don't think it of him you know it will close you up and so in this well the 2 times i was really. not scared in the can in the classic or a way it was me that was more way off. feeling lost and the like.

yeah so all and now it's the 1st time i receiving. drug therapy with mats and not getting cut open. that's a surgical feather fever. and it's it's the think it's a good it's good thing. but it comes with its own set of problems but in all those 16 use of this diagnosis of this disease and you still living your life i mean you're doing punk rock. kind of a boost yeah so how does it tell you you know. i am more like light. the whole mentality of punk walk so like being self dependent. freedom loving and. it's all can be transferred into the coping with the disease you know like being being self dependent so i

don't give in like i'm blind hear everything i question things i want to know what's happening i want that the doctor is. it's like working with me and not working on mean. freedom loving i'm not really free when i'm that i can feel your spirit and it's very likely for me to hear this but. i'm a father myself of good to girls and for me as a parent. it would be a catastrophe to learn that my child has cancer so even if you are a buddhist even if you do punk rock him how did your parents react to the diagnosis my parents where. i've this rule nobody crossed if i'm not crying so when my parents who are bad in the hospital and it was really it was more a more positive than life negative i feel like life and inject this one

almost more life a life demanding like he wants our life and our normal patterns are as close as it is get as it gets the parents are the rock for you and when you see your parents are grieving really badly it affects you in a way you couldn't imagine for in the fix you're coping with this disease so this is the reason why subconsciously i invented or i put off this rule let's continue this talking just a moment because you have to get therapy we're not in a park here we sitting at the shady t.m.b. lynn he's going to get you know therapy so what do you say immunotherapy. a vaccine that helps fight cancer. it teaches your immune cells to recognize chuma as more effectively and to attack them. just

moods it's even siri your immune system could kill most kinds of cancer but often it can't keep up. either the cancer is faster than the immune system or it can defend itself against them. into being in scientists the testing the effectiveness of the vaccine therapy in fighting we're currently kenya. before spring comes from . we believe the therapeutic vaccine could have a long lasting effect in the body for instance extended immunity against any residual income your cells we hope this protection could prevent a recurrence of the disease more youngsters bits of them stay. cancerous tumors form from the body's own tissue cells look almost exactly like healthy ones making it hard for the immune system to identify them that's why immune cells can't fight the chuma without help. the proteins on the surface of cheema cells are

altered and these are the target of the cancer fighting leukemia vaccine. every vaccine is tailored to each individual patient because every chuma is different. one advantage of vaccines that target cancer cells is that they don't have serious side effects. there is such as themselves produce the personalized vaccines 1st they look for the molecules that are only present in the cancer cells to do this they compare the cancer cells with cells from healthy tissue in that way they can identify the specific changes taking place in the leukemia cells. the test subjects receive 16 vaccinations over a period of 7 months after a while the immune system begins to respond it starts producing new immune cells

that battle the vaccine and the cancer cells. each dot represents a cell because that's the control group. and this is the vaccine response you see up here there are a lot more cells than there were before. the results so far indicate a regular vaccine response in the blood of patients we've been treating and. this therapeutic vaccine is still in the research feigns but another cancer immunotherapy is already in news. special molecules or checkpoints on the surface of immune cells prevent them from attacking the body's own tissue cancer cells protect themselves from the immune system by reinforcing this breaking effect. but new drugs called checkpoint inhibitors remove the breaks the immune cells abandon able to find each humans but the unleashed immune system doesn't just

attack the cancer cells it also attacks healthy tissue that can lead to side effects like joint problems and eczema. but it makes it possible to fight she moves that were previously considered untreatable. copy in the future cancer immunotherapy will play a greater role than it does now if everything goes well particularly all patients stand to benefit. you can i mean a therapy could be used to treat a wide range of team and in addition to surgery chemotherapy and radiotherapy immunotherapy is on its way to becoming the full failure of cancer treatment. this is where you do the fusion ferret piece so what's inside this container this is the foremost. immunotherapy and what does it do in the system it's quite

a novel approach. for so would you just know that the patient's immune system usually detect its own cancer or immune system has a control. the control over. it's kind of a break for the attack of the immune system so in this case it has is immune reaction but the controllers control that this infusion takes off the control for a period of time so we kind of loosen the break and then his only move to texas on cancer. and your student of biotechnology so does it help in understanding the therapy and does it help you get. yes a self-made to understand therapy but not like in a way that it helps you to cope with it it's more like. in the way that i can i'm feeling like i'm more than a scientist and involved in the whole treatment of the whole disease

cancer and just the patient just being a patient so and when i'm here and i'm talking to a woman after the therapy or before it's kind of nice to not just to talk about my own desire disease. me as a patient rather than talking about the whole spectrum of cancer treatment so what about it brings me to the side effects i mean you would call them and there would be. the serious side effects are there any side effects there are side effects at the moment i only have like a little rash like a little red dots or something in the torah just like this. here where a chinese port is a couple of those especially well i'm a belly. they just look. like a summit of limitation that's not really. manageable. here

there are some other. side effects that are more. severe but now i don't i just don't have them so what kind of side effects can you expect and what's the danger of. effect without tripping we're fact control of the immune system so the control that immune system has in its health so we do loose and display immune systems can overreact and and so had a very severe and or called itis was having diarrhea and that's when he called and for about 3 months we couldn't continue treatment until we had solved this problem he had to adapt his diet and after what he wants he felt well and the record continued fortunately doing the time so triple was the disease was already controlled so it didn't affect the whole result and what is there to gain from this therapy can you really heal the cancer we know from other forms of cancer which we

use this treatment that patients are not stable for more than 5 years so we know that they have a very prolonged effect hopefully and so as a model of these patients thus far the cancer is not to be curt we can find some evidence that he is in good shape just finished his studies so he has good quality of life and cancers controlled it's controlled so it's more like a chronic disease and i think if back to that so we would say that we defeated the cancer since we find some evidence we're always afraid to cancel my trip we curve but so far of for the past like 12 months it's completely stable and he has no symptoms so you don't really know whole whole long to continue the therapy could be for say 30 years we don't know yet we know from other patients that you can't stop for a while like another disease so we know that also was and so we had the wake of what 3 months and it did not affect the results the positive result but for the long

term we don't know it well but there are other therapies and colleges looking into . as. i was pretty skeptical about the whole thing i wasn't convinced they could help it i just thought i had nothing to lose. it's. yanis y. to has breast cancer she's an outpatient at the carey m. teaching hospital in essen in the integrative medicine unit here she receives mainstream care in combination with complimentary therapies mainly to address symptoms and side effects doctors have been a further help set up the unit. finn's always open 60 find a great fan of integrative medicine in general i think conventional medicine has its place and is important but i also think that your patent medicine has a great deal to offer and it's wonderful to be able to make that available to cancer patients as well. acupuncture is used here to help deal with pain we can be deployed during

a course of chemotherapy. this could diminish today and more and more studies show that acupuncture really helps with a range of side effects such as pain in the hands and feet nausea flushes hits of this has been thoroughly researched and we see it in our everyday clinical work which is insufficient clinician i'd. keep my ferret p. has caused her liver values to soar and has to be suspended until they come down dr ferber prescribes an abdominal compress as he has his mention of acanthus we don't have to just wait and see if the body deals with the problem while we pause the therapy we can actively support the process just as we know that a compress on the liver boosts the livers metabolism so it might speed up getting the values back down to normal so we can resume the therapy it can also turn off. after 5 weeks the values have improved it's possible but not certain that it would

have taken longer without the compress younus why it is worried that her tumor has grown during the break in treatment she's about to have an ultrasound. and i'm very nervous it's all or nothing now has the chemotherapy worked or not use it one day included looses the surgical clips where the tumor was you remember that looks black now there is no tumor to be seen around the clip before it's gone and can't be seen using now most of these are normal healthy structures with new connected. tissue growing as of this is off it's clear the tumor is gone what's in there to accomplish this comedy and you know mike you know this month or so this is . truly difficult for h.d. all tears of joy are important to him oh my gosh these results are fantastic. in clinical we have complete remission means there's no chuma we can hope for anything

better. you have to be really strong i think i have been. there were bad days but i feel like i got through them. before the ultrasound younus quite a fear the tumour might have grown in fact the chemo had evidently already obliterated it. the complementary therapies didn't target the cancer itself but we used to help her deal with the side effects and support the therapeutic process. i must say i just met and saw it today and i'm very fascinated how he's coping with this diagnosis cancer is the usual approach of patients it's a very special situation for this and patients usually just fly for independent at this age patents are soaps good studies they're good jobs the co-op of the family and so in this phase of independency they get dependent on medicine on people like me so it's very difficult for them to integrate the disease into

a normal life especially with chronic diseases but i'm also very fascinated by these patients because they're also very mature more mature than their peers so it's what makes it so special to treat young cancer patients well there are several aspects one of them also is certain now have an amount of multitude of information available to just use to look into the internet what's available so we talk a lot of quantity of information that doesn't always mean quality so you will have to talk in-depth and explain what you are doing well and says quite confident quite witty he says that a doctor has to earn the trust of the patient is he right what's a little perky but it's honest and honesty is the basis of a working patient doctor relationship since it's almost i can handle it. thanks so much for this very interesting talk and i have so many more questions to ask but now it's your turn to send me your questions. on an

upcoming show we'll be talking about. it's consumed all over the world mainly in the form of wine and beer what effect does it have on the body sending your questions to in good shape but deja blue dot com just right alcohol in the subject we're looking forward to hearing from you. so right now after therapy how do you fear. later today or gets tired will be tired and it's like. cats ok if somebody gets a diagnosis of cancer what's your advice for these patients yes i would say i. try to depend on the family so what i say before. the beginning of the disease and so then you can. be supported by your family and the latest data shows

all when you get like. another disease. thank you so much for sharing your story with us and we'll see each other again next week and let's all try to stay in good shape and we'll have some yes ok.

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