too often and then you should contact the drug dealer or if the quality of life is reduced by the same terms so try to relax over a bottle or next to death. so let's talk about colon cancer which is kind of a common disease which mainly affects older patients but sometimes even younger patients as well so i see. how their sound correct how cancer is caused by genetics changes their families with for example the syndrome the high incidence of correct cancer so you can lie on your family and look. around their colon cancer or breast cancer a very rare cancer is curing and if it's like that you should contact your doctor and ask him for screening crims computer communications now we talk with professor starting about colon cancer in her research at berlin's marks the center for

molecular medicine she discovered a gene that increases the likelihood of a trooper in the colon metastasizing. we're talking about colon cancer like like this year it looks like this year the model and you discovered gene a very specific gene which is will breaking news what about how. basically to understand the importance of this discovery we have to know what metastases all the tests is is basically the most used of cancer so they are decisive for patients survival they are the size of what the subsets of so if we could test this is all even. even if you could put the last decade in the tests this would be a big step right and the gene is actually doing so and then 10 years ago we had this idea of the might. we might identify

a nova gene and this nova gene should have ideally the ability to act as a cancer gene which can pop gnostic 8 tests this is left of oats and which may be by itself might we please send a target for target so meaning that if a patient has a tumor and industry were is this special kind of gene there's a high prevalence of metastasis absolutely we have now follow ups of 17 years and our partners to keisha percentages so the probability that a patient is high makes it look at later on in the tests this is about 80 to 89 percent which is quite high and this gene is right here in this tumor sort of thing that the smaller than the gene is basically it expressed at the 2 more rim ok meaning in these areas you will find those which are very more tired than

my weight which can invade the 4 into shells and they're the next yes ok but if i x. 7 with humor i'm not too sure if i'd take some example from inside the tumor here in the middle so there are not so many genes so what is a diagnostic test i can use as a clinician in addition to the tumor based s.a.v. also develop the blood. in these blood based us a you clearly see that you have a significantly longer survival if you have low amounts of makes you and your blood perfect so it's more like a simple or not so simple blood test and it can tell you a lot but what about therapies out there some fear purity could produce targeting this kind of gene yes identify it. molecule it's walks with cooks in the inhibitors and lucky if these already approved by the f.d.a. for other purposes and not doing the pope are saying this these already.

approved. easy clinical trials so we know that those drugs are effective and other kind of diseases they're kind of safe to attend understandably although you just it's known so there it is so there will be drugs in the near future we don't have to wait for them say for 20 years no no no if you have the position the pope has struck then the pipeline is much much faster so that is very good news thanks so much for this very interesting talk cancer is treatable in many cases but we should still keep in mind that early diagnosis was very important. in good physical shape. for a while though things were a bit scary the 60 year old had never bothered to be screened for bowel cancer and when he finally got around to it the results were worrying. and. i kept putting

it off but we caught it just in time. i guess i have my guardian angel. only made an appointment for a colonoscopy because his doctor kept insisting. he was feeling fine and he thought the common diagnostic procedure wouldn't reveal anything. in this moment of 2 to slit cause i was shocked right after the examination when the doctor told me there was a 5 centimeter hole up in my colon. and that he had removed 3 smaller ones straight away. that i fly new like a clone would he couldn't deal with a big one immediately because of the risk of bleeding stone close and no blood to move. polyps can grow on the inner lining of the colon there are various types many are harmless but some kind of eventually turned cancerous. the polyp then

begins to grow deeper into the wall of the colon and beyond once the cancer breaks out of the intestine it can spread easily via the lymph system throughout the body . in a worst case scenario it's already metastasized when it's diagnosed and is no longer curable of course that pains us as doctors you think if only the patient had been screened sooner. or had to have the large polyps removed as an inpatient in the hospital. christiane puck's is a gastroenterologist and oncologist he decided on the exact approach to take. 15 it was pretty intense. it's or he wasn't sure at 1st whether he would have to remove a section of the colon as well. so i was very nervous. ultimately

dr pocs was able to completely excise the offending polyp without removing a stretch of colon he accessed the spot using colonoscopy. it was still pre-cancerous what's called stage 0 after 2 or 3 more years it would very probably have turned cancerous. there's a. screening can prevent many cases of bowel cancer the trouble is that even where the service is easily accessible like in germany many people just don't go. to determine cases of colon cancer and identify precancerous growths a colonoscopy is really the key diagnostic tool. for the patient the unpleasant part is the preparation laxatives and liters of fluid ensure the colon is empty and clean. the colonoscopy itself generally only takes about 20

minutes patients receive a sedative so they don't feel a thing a flexible tube is inserted into the patient's rectum and guided through the colon a high resolution video camera at its tip sends images to an external monitor. this is the quality of the images is so good that we can see anything problematic even if it's just a few millimeters in size the. studies show that the age of diagnosis tends to be lower for men and women in germany gastroenterologists say men should start getting screened at the age of 50 in some countries the recommendation is 50 for both sexes . the point is the earlier we find polyps the better. but screening only works if people actually do it i'm going to. do to his medical history over

harbors we'll have to have regular checkups from now on he's living proof that prevention is better than cure. so does the hurt and isn't anything to be afraid of but no you don't have to be scared nowadays we prefer appearance so that the patients can't sleep during the whole examination and they would not even remember ok but it's still a little bit embarrassing isn't because before you go to sleep it's a sensation you have to pull your trousers off yeah i understand that companies can have. offered. special trousers who have skin. patients who can't choose their gender if the doctors say it's easier for the patient to have this very comfortable especially here in germany because we've got a wide range of gastroenterologist working here but in different countries there

are a lot so many religious so who should definitely go for a car. and if colorectal cancer cure your family you should go to a screening come escapade and if you have a bleeding rectal bleeding if your pains and the bally changed a few occasions it's thanks so much for this very interesting talk and i can totally understand if you want to have a kind of last complete now and if you want to make an appointment go to your computer and look for gastroenterologist and if your computer freshmen you are. in good shape your weekly help show on g.w. covers many aspects of health care we look at what's new in medical treatment nutrition fitness and we discuss these topics in depth with specialists and offer you. opportunities to pose your own question so get in touch.

i know we didn't have the time to answer all questions about the color but the good news is there's still many of us it's of in good shape coming up next the result the next week c.n.n. .

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this is g.w. news live from barely indonesian teams recover what is thought to be the end of a passenger plane that plunged into the shop a scene with dozens of people want for x. comes just hours after they locate a flight into reporters also coming up on the show from prison to president a nationalist when security is down to presidential elections by in landslide just months after violent protests ousted the country's previous government decided to tara is promising expression start and an end to corruption. and

a sex workers face financial distress and increased risks to their health during the brunt of tyrus pandemic restrictions often means they are unable to earn a living unless they defy a ban on prostitution to meet a sex worker in a belgian. a little. poem claridge it's been welcome to the show indonesian search teams have recovered wreckage of the engine of a passenger plane that crashed into the java sea on saturday an air crash investigator has now said the jet possibly fell apart when hitting waters 62 people were on board a boeing 737 aircraft authorities have also located the flight recorders they hope the black box data will clarify why the plane came down in just minutes after taking off from jakarta. looking for clues to make sense of

tragedy indonesian search and rescue teams sort through debris found by divers in the job to say body parts and children's clothes were among the 1st items retrieved from the water. already located the plane's black box recorder confirming the debris is from the missing boeing 737500. still hoping for unlikely good news the relatives of the 62 people on board meet with authorities where they hand over d.n.a. to help identify potential victims. no 4 people on the plane. leaves in the cahsee her husband lives and works here so his wife and 3 children planned to visit and holiday here in pontiac but it ended like this. air flight left to carter

airport on saturday down for a 90 minute journey to pontiac. but lost contact only minutes after takeoff data from online service flight radar 24 shows the plane suddenly losing altitude and speed. boats will continue to search the ocean as authorities try to piece together what happened to flight s j one a tooth. for more on this story we spoke to journalist cress nast traveler in the intonation capital jakarta and asked him about the flight data recorders that have been located at. black boxes has been located a navy ship that signals from bowls. look at to be gone transmitted from was that of one of the cockpit voice recorder and it was also confirmed by the davis that being said you know this to see if it is.

full of across the business you bet. the next challenge is to find and if both black box this. although it mainly in the shell of what i heard it's only less than 20 minutes that's all ron about when they made this but. this said the man that is quite big. also with the cotton physically the man of the good but. it also may be but it under this had you been but the navy commander that. he is very optimistic that they would be found soon and then hopefully tomorrow. to the united states now where a 2nd republican senator has called on president donald trump to resign in the wake of wednesday's deadly riots at the capitol it comes as democrats say he must be held accountable for the violence they are preparing to impeach a trouble for a 2nd time despite less than 10 days to go before trump leaves office lawmakers are

expected to formally introduce the proposal on monday in the house of representatives. quiet off to the storm like seems to have returned to normal in washington d.c. off to donald trump supporters stormed the capital on wednesday but the events have left them mark. i was appalled disgusted being free i'm a military veteran i never thought i'd see this in the us the events of this week have everybody in the city a little bit worried and i've been walking around and seeing still a lot of. supporters hanging around so it makes me a little nervous that there are a lot of people staying many americans are still shaken by the images of void nationalists and confederate sympathizers running around the halls of the capitol these images will never be forgotten and people wonder whether this could happen again security has been ramped up for the inauguration even the national guard has

been mobilized the whole city is on high alert it's time for the u.s. to move forward the question is in which direction one of them could be impeachment for a 2nd time democratic lawmakers say they could start the proceedings as early as monday charging donald trump with inciting violence more and more republicans are also turning against him while i think the best way for our country truck is for the president to resign and go away as soon as possible. knowledge that may not be likely but i think that would be best. for regardless of the outcome the events of the past week will cost a deep shadow over donald trump's remaining days in office. and let's take a look now at some of the other stories making news around the world more than 2

weeks after a camp for migrants and refugees burned down in a leap up bosnia more than a 1000 people are moving into heated tents provided by local authorities the stranded people mostly from pakistan and afghanistan are trying to reach western europe and have had to endure miserable freezing conditions. several 1000 people have rallied against coronavirus restrictions in the czech capital prof he said the closure of restaurants hotels and other businesses has weighed on the economy and triggered a rise in unemployment and poverty the demonstrators largely did not wear face masks or abide by social distancing rules. but across a virus pandemic has brought economic upheaval into many people's lives for sex workers it's meant a choice between no income and serious new health dangers to max and or reports from belgium she says she loves her job but for belgian sex recruit

life has become an uphill struggle. because you want to know as well saying all day is a challenge i notice that every day i'm getting stomach cramps because the situation is so stressful because if i get caught i'll lose everything if i get fined out today tomorrow and be in the street the national the 27 year old left her job to begin sex work full time a year ago letting strangers into her home was never entirely safe but by defying the lockdown ban on prostitution now she's taking an even bigger gamble sit back and make me sit up on his own if. it isn't like aids for example where you can just wear a condom and be protected end of story it's much more delicate it's like playing russian roulette but the end of the day i'm an adult and i'm choosing to take the risk so are my clients on their own who would a common point so this she says she has no choice but to keep working like many others she operates under the radar because there is no legal recognition for self

employed sex workers that means no state benefits for income she'd lose during lockdown well prostitution continues behind closed doors the windows here against red light district remain empty buying and selling sex isn't illegal in belgium but making money from the sex work of others this campaign is warned this gray zone offers fertile ground for discrimination if a sex worker wants to have a loan an insurance if she wants to rent a house she doesn't have payslips to show how much she earns. if she goes to a bank and the bank has some suspicions the bank will say like ok maybe you're a sex workers and if you're a sex worker we will not give you a loan we'll give you no accounts we will give you insurance because then we are punishable by law there is hope for a change in policy belgium's new government has vowed to improve the living and working conditions of sex workers but some more this misses the point entirely support organization for women working on the streets of brussels wants to see the

evolution of prostitution. taking the inside from what we see on a daily basis prostitution is sexual violence and sexual exploitation and women are women and children boys and girls of our. main victims of fate she also wants things to change but for her the priority is legal recognition to give thousands of sex workers here the security to weather future crises the people at the heart of it say this debate can take place without them. and some news from central asia now and curious and interim president has won presidential elections by almost 80 percent according to local media reports side edge a part of has been at the house since the previous government collapsed following october last october following violent protests he has promised to end corruption in kurdistan a close ally of russia. election day began with

a national anthem there was a lot at stake kyrgyzstan voted not just for president but also for constitutional overhaul giving the leader extensive new powers. the nationalists politician saga of was always said to win gaining popularity with an aggressive campaign making sweeping promises. to start the middle whatever the result we must respected in order to have peace in our country the minorities must give way to the majority but she's going to kyrgyzstan is seen as the most democratic of the former soviet states in central asia have revolution 10 years ago in parliamentary democracy. but the government plunged into crisis over discredited elections last october ship out of 4 serving

a prison sentence for hostage taking but was later released. now he's the country's hardline new ruler. it shows how popular trust traditions about corruption and the rigged elections and the current management can be hijacked by elites with connections to the criminal organized groups in the kidneys. shut part of emerge as the runaway winner backed by merely 80 percent of the voters who also granted the new president his extra powers. at least 4 people. have been killed after spain saw its heaviest snow fall decades prime minister pedro sanchez is appealing to people to stay indoors but much of the country still at a standstill were can see crews have rescued at least 1500 people from their stranded vehicles. storm filomena brought 60 centimeters of snow to madrid

the most the spanish capital has seen in half a century despite widespread disruption many came out to enjoy the free conditions with mass snowball fights breaking out in the city center raising concerns about social distancing not being maintained. there's been quite a concentration of people it's a shame because with the pandemic i don't think that is the most prudent thing at the moment but when. there aren't enough shovels and a lot of young people are just throwing snowballs when they could be helping we're lacking leadership from the politicians. the army has been mobilized to lead the clear up with assistance from hundreds of civilian volunteers the focus is on keeping access to hospitals clear as many are due to receive deliveries of covert 19 vaccine the worst of the storm may be over but weather experts are warning people to be aware of bitter cold over the next few days. we must take extreme

precautions and all our daily activity the snow fall and hit the peninsula with unusual force is now being followed by a cold wave with minimum temperatures never reached here before that requires particular caution and patience the government is organizing convoys to carry vaccines and food supplies to areas cut off by the snow fall and the goods mayor is warning residents that for much of the next week it will remain difficult to get around. time for some sports news now and the latest a buddhist leader action arjan tiny coke on sat as a scored one goal and made another ashqar returned to winning ways as they won a convincingly at. the home side had the 1st chance of the match when danielle paige jury rattled across far up the visitors event hit their stride as bhansali as the stench the keeper the wrong way she took out 2nd came from a sweeping

a counterattack. this was their 2nd goal and or want to victory that was their 1st win or the matches. that is your news update at this hour don't forget you can get the latest on our web site t w dot com and claridge has been in berlin for me my whole team thanks so much for watching. kick off. this town atmosphere means listless clay. from the. looks of guns and bullets flying since the. nonstop excitement in the final match to.