1000 for 65 years old but i think and work you know in the. 1992. carl june was named one of the world's 100 most influential people by time magazine in 2018 the 1st actually test of this is in patients rather than get factual because they have lost 3 of the virus many of their own t. cells. 2 years later my wife died of ovarian cancer in 2001 and so i really needed to move from hiv the to do really all cancer work at the time however he did not receive a dollar from the pharmaceutical industry because the treatment initially only worked on mice but not human it's ok what we know for sure is that the. fund in essential way was essential to make a new industry so to have philanthropy and the government support it was

millions there was millions it was probably $20000000.00 i mean. i think for sure $20000000.00 were invested between when i came to university of pennsylvania in 1900. until nov artist at the alliance with me in 2012 but the riskiest part was state and government yes all the initial research that showed this new concept of our car teams could work was. academic laboratories. in $22.00 and came the breakthrough in the cancer patient douglas olson however it was the news of 7 year old emily whitehead that spread around the world to save the young of kenya patient's life and even 7 years after the infusion she remained cancer free. the treatment is more effective in children than adults. we had hundreds of calls for a venture capitalist warning to start your companies that fortunately had no heart

us call us about why their commercial artist. inventing a drug is one thing says novartis but putting the research into practical use through a market launch is costly and time consuming insiders say no parties paid the university of about 225000000 for the exclusive right to sell q. mariah and novartis is paying the university about 5 percent of the sales price for each infusion the group has no comment on this the health care industry is not transparent and it's not been designed for the benefit directly of the patients and transparency our most recent estimates. are around $55000.00 just to make the card. that's our cost per patient and with no profit. so the actual cost is almost $7.00 times cheaper the university however had only

done small scale trials with camera while novartis had to fund world wide studies to attain market approval and build centers to produce the treatment. to. make a dime is still waiting for his cancer killing cells from the us when suddenly a message comes from nova artists the group will give him the riaa for free. plus the most mid of all things were filled with joy and very really isn't it if the beak mean you always a lot of money at stake holes of azza will start their own cult of what about other teams riaa patients standing looking like. those i don't know novartis is a plaid seemed the friend ethically it's a delicate question as to whom novartis gives free treatment iana to yes of course . the 1st 2 swiss patients are being given t. mariah for free because negotiations with health care insurers are taking so long

no farkas explains. mikail a father of 2 children will ultimately lose the race against time nope artist's usa informs him that his cancer killing cells have not managed to multiply well enough to produce camera. 1000 days later he dies. my name is paul cloyd can then in the pharmaceutical industry for 30 years in the

last position was a us president and chief executive officer of a company i am retired now and over the last 5 years i have been dealing with and then curable cancer. so car know what its like to show us all the medications that i have to take in a day. this being the most important one just as my anti-cancer drug. disprove it to take one of these capsules for day the cost of those a $750.00 each and entrusting only enough they only cost $1.00 each to manufacture. what do you think about the price of $370000.00 swiss francs for a camera that's ridiculous car it should never happen this is a product that was developed at the expense of the u.s. taxpayer did you have a different view when you were still

a former manager then you have now on your industry. the answer is. yes caryn and. for 2 reasons 1st i was not a patient i've been part of the system i've been a my family's been a beneficiary of that system. i really didn't know any better at the time you know you go to work at the get a perspective which is the company perspective and what you learn as you get older is your perspective becomes much wider. than is the former c.e.o. of a company acquired by no bar to see in 2002 he says no participants so benefited from a 50 percent discount on the cost of its trials or the camera this was the us is way up incentivizing research on a rare disease or it's people like myself who actually have funded the development pro at the development program or half the development program of come right out

and what we get in return is basically a punch in the teeth from the artist. he created a price model for camera based on no participants claims that it had invested over 1000000000 euros by the time the treatment was approved. i calculated a fair price current of $200000.00 or infusion in 2019 using the assumptions using the assumption that novo artists were generated total of $1700.00 patients and fusions out of 14. out of 14000 potentially. goes on we can actually drop that price it can be reduced to about half of 370000 francs the fair price is calculated in such a way that no bar to sit cheats an average operating profit of 20.7 percent the research costs averaging at 17.3 percent are also included in this calculation the

health insurer associates. sometimes there's also demanding a price of 200000 francs for him right. i've looked at the document you send me a document is full of incorrect information thank you for the correct information i cannot give you that and i am up i cannot comment on it because it is not ardent da our data is not our document the criticism on the farm are not just not artists but on the farmers in transparency it's growing worldwide we hear it we age o.b. hear it with the health insurers with the public because the public is the payer. are you afraid that this will damage the image of nobodies. are not afraid of damage to the to novartis or you mention in transparency transparency is required across the system not just from one party our government is asking for transparency because we have a transparent list for prices i think it's the opposite. or it can be discussed in

a broader group i think it's a bit it's a different conversation. 71 year old court bending they are also has left no cancer and he says if he has the strength he goes out with his dogs because of the price dispute he has had to wait 3 months for the health insurer to decide whether to pay for camera. quite could you afford it if the health insurance didn't pay when he owned approach i were 100 percent sure it would work i would sell my house so but i can't if it doesn't work my wife will be left with nothing that's out of the question in my eyes that ever it is that most of us have and it's if a company didn't pay for you or you wouldn't do it me no it's too risky stunt

because the low chance of being cured you know. each year around 110 cancer patients in switzerland who have undergone all other treatments to no avail receive camera and the 64 year old teacher and honchos are in burn land is one of them. if we don't have. the question is this what is a human life this is to put it bluntly you are over 60 if a young person asks how much longer do you have left is it even worth it when curing your illness is a best case scenario and does it hurt to hear that kind of question. now you have it then can it be now and it's now you know but i've also met young people in the hospital who are in greater need when you look at it that way. i've lived a decent life and it's been nice so far sharing since every. time i almost feel ashamed even though i didn't set the price you feel very uncomfortable and so

guilty but it's the only chance he has left of course you're not going to say no. do you feel guilty sure. now i really need billy not really i was in good health for a long time and paid premiums for decades it never really needed anything that i might be matson to have to throw this came as a surprise that i should of course his health insurance is also paying for him right now. the price negotiations between the insurers and novartis took 4 months with the price being haggled up and down like at a bazaar. some insurers threw in the towel while others came to an agreement with novartis. 4 insiders say insurers wanted a 45 percent discount on camera out for treating lymphatic cancer which was too much for novartis they instead agreed to a 20 to 30 percent discount to pending on coming riaa success rate meaning about

250002300000 francs but no one is willing to talk about. the agreement after all is confidential in fact it is so shrouded in secrecy that health insurers such as concordia which were not in on the deal will not even find out their discount until they have signed the contract coffin with think it's scandalous this is the 1st time i know of for us to conclude a contract where we don't even know the price was issue that's unheard of in swiss health care where prices and contract closes a normally transparent. you can usually check what you have to pay for hospital treatment and cost transparency is very important in health care otherwise we subjugate ourselves to the big corporations. court pending or has to have another cell sample taken because novartis didn't

manage to produce the cancer killing cells in the us as they did for me. in a school it's clear of course it doesn't feel good things were looking up and asked if his event there want an off cells it's training. in the approval study for camera one 3rd of patients could not be treated at all either because the cancer killing cells couldn't be produced the patients illness. had progressed too far or they had died waiting like mikail moonshine. anton schlosser receives good news from the us his cancer killing cells have been successfully produced and are on their way to switzerland under comes it is immense and so then you get about these cards and cells cells that are even stronger than normal immune cells and in the last many moons and when immune cells get into action there are side effects last

time isolations may experience fever circulatory problems or even organ failure. in that site at best kidney failure for instance has been observed in about 20 percent of patients once put some of the needed dialysis that dust had settled parts in. and material used as a potential most. cancer killing cells can heal patients and kill them. so those cells are the last hope for those who would otherwise die of the disease. you know michel for jerry my name is alfred scheidegger and i'm a risk capital investor day here in san francisco i'm attending the world's biggest health care conference. invests in small biotech companies

developing new cancer drugs. have a good day about his goal is to sell my small companies to pharmaceutical companies for a profit. so. this is our a very good i just do not tell you whether those babies were doing. as good the truth as your mr shining or what's going on here that's a shock. it's like a marriage market it's unbelievable. if you run into all kinds of biotech companies especially own political ones mafia with pharmaceutical companies aiming to take over small companies later on once they've provided proof that their cancer drug is effective in humans like we're doing that it's in the top. 60 percent of new drugs are not developed by pharmaceutical companies but by small biotech companies they need

a lot of money for studies with patients and this money comes from investors like alfred scheidegger and marcus horsa. try to gross company often invests during the early stages of research but the pharmaceutical industry pays the most when a biotech company is about to launch a new drug on the market the artist is flying the u.s. for valley of excess the price secondly $90000000000.00 nearly atlanta has agreed to buy kites fire now for almost $12000000000.00 no vargas is now demanding a record price of $2100000.00 for of access treatment in the state the vicinity feels there are calculations involved that have an impact on the price hike in the past you have to gain back your investment and of course that's part of the market price in the event based on the style of souls for bach plays with him riaa no artist managed to avoid dealing with the biotech companies for investors by signing

a contract directly with the university saving them billions. for patient court bending or at a hospital camera is able to be successfully produced on the 2nd try. to do your future $43.00 millimeters cost 370000 francs. does that is this is a discussion that i frankly do not want to get into now at a patient's bedside young i've still got a life to live. i feel like i comprehend you have high hopes it will work. anton shows i received his infusion 2 days earlier. yet similarly did i miss how you doing fine so i. heard it tired right i fall

asleep even if i want to watch something. mechlin would tell if the camera is working and this is a cinch for the heart it's too early we hope so of course but we can't tell through for whom we have high expectations of course that's there it's it was all asking me for a moment no government representative on the phone informs her of new problems with humira since it is considered a hospital treatment the cantons have to cover 55 percent of the costs. name they are stocking us up no we're starting the process in parallel to buy the car because of the cost it's a vicious circle because the health insurance only covers the costs if the cantonal government also agrees to give its part of the supplies it does properly allow for by you know each of them says they'll only do it if the other has already agreed to stay in touch.

maker and it's we meeting with jenny lee an investment banker from hong kong where she covers china they clean up. china conducts the most trials on cancer killing cells worldwide and market observers say if the treatment is approved there it will cost about $70000.00 to. tread and i don't think you know that really is that lots of people yet agree jenny lee says the chinese government is putting pressure on pharmaceutical companies not host of course then they have to lower their drugs so the approach they are marketing is that they are a bit yappy that because you'll like a new game yes that will be a huge volume of the clock so that was all the of the volume if the phones that accompanies read my mind those high priced really the tiniest market cannot afford

the chinese patients who are in our insurance system so you'll be all lost lost that. are. also used this about profit or saving lives psalm of the. sixty's existence the existential justification of a private company is to generate profits while simple feat. and that comes before life. you. you can't really ask that question. and those are just wired documents his treatment using a cell phone. while you sat. depressed no. agitated. in the 1st days

he has fever and chills so only minor side effects. it's the same story out in social retard with court bending are coming down with a fever but otherwise he feels fine. so do you feel like it's doing any good. or i can say that we don't know yet there. are heartless. owners and this biotech company is researching in the booming field of medicines for rare diseases referred to as orphan drugs just like a mariah when you say 3 locations there. are 3 years that you think we're focusing on. is an issue yet. in the us and e.u.

orphan drugs receive exclusive marketing rights with similar products from competitors excluded from approval for up to 10 years states each is old to the 6 a little or is built to incentivize research because once you obtain approval you enjoy a sort of exclusivity for several years a competitor can just launch on the market that's exclusivity told to locate the greasy excuse eat it. in the us the orphan drug act was enacted almost 40 years ago today the politician who initiated it with love meant that some pharmaceutical companies are exploiting their monopoly to increase their profits. the topic of orphan drugs and market exclusivity also reached switzerland a few years ago.

ladies and gentlemen pursuant to council regulations for engaging in the debate on this topic i hereby disclose my vested interests. i am the president of into going to the swiss association of generic drug and bio similar manufacturers. in order to promote the development of medicines for rare diseases pharmaceutical companies should enjoy market exclusivities for 10 years for orphan drugs during this period and no other medicinal product should be approved for the same therapeutic indication unless it is proven to be safer or more effective if you're. the point is the point is pharmaceutical companies are not social institutions and they only conduct research when they expect to profit from it this people have to know in order for new drugs for rare diseases to be introduced at all it takes a monopoly and this is achieved through market exclusivity we'll push the market exclusively to it because often. when sebastian trainer was voted into parliament

he gave an access badge to no artist lobbyist at the time while no barters and rush donated nearly 900000 swiss francs to the middle class parties last year and that the power to mislead fest still at the end of the debate it became clear to us it was not the patients who had gained anything it through this revision of the law on thursday you see a product recently out on king well hit caution no but instead the main changes had been about his coffers to be filled up even though no from all the code i need i'm sorry throughout the commission's deliberations and still here today i feel like i and perhaps others here too i have only been aware of a fraction of all the lobbying going on here in the background of the op i wanted the rest since the 30 ft old us had called and that had consequences. but i received a reprimand from past. then the head of novartis the. 3

chiefs and what did he say. you're all he emailed me because he wanted to meet with us and discuss our stance for methadone so he claimed we were not being pharmaceutical friendly in the law making work that hard to be there i thought it was outrageous for him to interfere with my parliamentary work in the parliament are the shelf that had that ever happened before i never experienced that previously or again at last. the debate went on for 2 years and the national council voted in favor of market exclusivity twice but the council of states opposed it the monopoly didn't pass but instead a stripped down measure protecting orphan drugs did. one month after the infusion with kim rajar and tom schlosser is thoroughly examined. did kim royal work and has the cancer disappeared.

yes now my i'm 1st going to show you the old pictures there was this lump here or that there was the main mass in the fashion compartment. and of course on your lower leg. it's called now here's afterword with just some slight activity flower activity ted at the top there are still some in the fashion compartment but it's already received there's a lot. when they go out. but it's many i couldn't have expected things to go any better you know for that our old tumor mass has completely disappeared without a trace of inflammation can you tell if he's in remission or could the cancer come back again. we don't have a crystal ball we don't know this but it's a good start actually obviously. the scan you can never rule it out but with kim

treatment rates with carty cells they still need more data not to quote. meanwhile tough quote pending his cancer also disappeared immediately after the treatment. of course i'm glad i can get home and on down wearing this mosque. take care and enjoy life and use the cover off that's the good to see. his doctor doesn't want to give a prognosis according to the no artist study it takes about one year to know which patients have overcome lymphatic cancer for good. more than half die. and it's not yet clear how the cancer cells develop in the body in the long term.

in this brave new world of health care the cost of a chance at survival is exorbitant. to mariah is just beginning. to go off. ghost town atmosphere means listless play stuff from the. looks of goes on down the list flights sensible. known stump excitement to the final match to.

see gotten a. good. 30 minutes on d w. they dreamed of more runs and more freedom freedom. freedom the. egyptian women and the hours we fought in 2011 that would be going away and we were going to. the story of. the liberation as told by 3 courageous women. are 2. minutes. of life. coming to an end. but

gigantic coincidence. previously the earth was just in a messy chemistry of all the. wonders of the impossible. through. the creation of our solar system with our planet is a bit like winning the lottery and there are some good. ones from birth. starts feb 11th on t.w. . as a state of the news and these are our top stories european countries and the united states are among those who have condemned the military coup in myanmar the country's armed forces seized control of the country and detained defacto leader aung sun suu kyi and several other senior civilian officials the military accuses the government to failing to act on claims of voter fraud and last november's

election. german chancellor angela merkel and state leaders met with vaccine manufacturers.