mass which we were getting extra. often. actually happened to an economist now about how to go i don't don't have to dream dream big all the time son just dream small a nice and small things. and. all it took was a father's love and the image a nation of a group of artists wings to point from england. watching g.w. news up next a documentary film the tower of the part of companies on terry mark thanks to. imagine how many push the old loves us right now in the world climate change is very hard to store faces my plastic waste from just one week. how much worse can it really get. we still have time to ask i'm going.

to access. the gnomish me. my name is michelle and munched i mean i'm a father of 2 children because i was diagnosed with cancer of the 3 cold 2 weeks later my life looked radically different has never been the same so it's unclear. even 2 rounds of chemotherapy couldn't treat mikhail's aggressive cancer only hong . create a self so if left untreated i would die in 2 or 3 months at best just so it's incredibly serious. his my last hope is a gene therapy with cancer killing cells such as kim mariah from novo artists with a price tag of 370000 swiss francs and camera is just the beginning

of a new drug let's turn it was injected into the body of $150000.00 sold gens it's now the most expensive drug on earth the price tag of. $1000000.00 how willing are society to bear the costs of loophole that are going to let someone die to save money. how are these prices calculated valmont do its utmost on the coals pharmaceutical companies sound the market to determine what can make it house of it and with the limousines the film all. good health insurance companies pay these record prices. 437-0000 francs is a lot of money and the cons of thought it was what can you do. it's tricky it's hard to tell what the future has in store for.

all sure what we're going to get this cancer. let's hope. mickael die and has a rare and aggressive form of lymph node cancer his crooked mouth also comes from the disease. his last hope is kim riaa a completely new treatment just approved last fall. samples are taken of the patient's own immune cells and these are sent to a noble artist laboratory in the us there the cells are genetically modified and reprogrammed into cancer killing sounds. after being multiplied and frozen the cells are sent back to switzerland. the patient receives the killer cells in one single infusion with

a price tag of 370000 swiss francs according to the novara just catalogue. it remains unclear whether the health insurance companies will pay for camera they have joined together to negotiate a discount. i'm melting of ice and i work for the insurer has done where i negotiate contracts with the pharmaceutical industry we're currently negotiating the price of kuma with no volatile. the price is too much she says partly because it is unclear what long term effects can royal will have and whether the cancer will return. official and it isn't quite clear to us how the price came about we didn't receive any cost breakdown and don't know why the price is so high it's all the way it's good now is all. the pharma companies provide that gonski formally and there is no formula as to how the price breaks down and i've never seen on the whole i mean this and i think they try to start with as high

a price as possible because in the end it always gets negotiated. the 1st price they said is just a starting place it's off now it's a real problem if you ask me i couldn't tell you what we can do about it because in any go. they discussed whether health insurers should pay. only in the event of success but what is success when it comes to cancer there's no solution in sight and for the time being every insurer is deciding for themselves. time's low cost to shore up to pre refuses to pay for kim ryan the benefits are not clear enough they're saying. to be honest i was furious as well because this stinks of incompetence if you're in the end it's like the wild west of the life that those who can afford treatment so the ones who get a chance to have. and for others it's not clear whether they can do to your health care yes. mchale's relatives want to fund the treatment

themselves but the hospital is demanding half a 1000000 francs as security. after a camera infusion some patients reactions require transfer to the intensive care unit to leave because. goblins kindly willing to give 850000 franc advance on their inheritance. fop to its credit also you know. i'm also getting an advance on an inheritance. when my brother spot their houses they call their share and i haven't needed it so far so but soca want it now i'd like to use it for this and it's also cool. it's usually it's not me but i was except a cd to get it really touched me that a lot of people i know are ready to give 10000 francs if it will help saying they know it isn't much so. that there are

a lot of kind people like that and it really touches around the whole who benefits because everyone realizes that in the worst case scenario the money will simply be going to fall out and in the very worst case it won't even have done any good if all. according to novo artist one and a half years after treatment 40 percent of patients like me. still have cancer. that's a start but could it be better. of course but the drug i'm currently on had a 20 percent chance of success. in the south was good there were days when i thought that's it as he gets older. i could only hope my final hours would go quickly told us this done i didn't want my family to have to watch forever and for me to be a never ending with a work out committee and i didn't want to lie around like a vegetable on drugs all strogatz with the roots to cook music in the dog.

about a dozen cancer patients cannot be treated due to the price dispute critics might claim the health insurers are at fault with terminally ill patients running out of time and dying while negotiations my gone with navarre to see the fall of the euro or there's this level of neither thought of it but that's not the case we all share the responsibility because we have yet to find a solution to this all around less than ideal situation follett it's not so. mikhail monch times family has scraped together half a 1000000 francs he is the 1st lymphatic cancer patient in switzerland to receive can ryan. good to mordor. mikhail has

a muenster house taken from him that will be shipped by plane to the us where they will be converted into cancer killing cells referred to as carty cells. will the treatment work week aisles cancer is growing so every day counts. the end of it takes a while for the cells to be produced in a best case scenario it will be 4 weeks but it may take a little longer since so many products are sent in public that i'm concept of but i'm called to. go ahead to ensure the funds are available to go come to ny is prepared to issue a bank guarantee that i and we are supposed to deposit everything into a special escrow account that spec your stance and we'll make sure it's not touched a bit but this way we can proceed with treatment by their father murphy earlier lymph node. it. was. moved through clinical trials funded by

novara case. here i can feel at least 2. experts criticize the fact that the effect of can riaa has been tested on less than 100 patients worldwide the follow a period was less than 2 years and came royal was not compared to an existing treatment program on term of facts remain unknown this criticism generally holds true for other trials on bring her disease and. naturally patients want the treatment as soon as possible and the companies present the study results as positively as they can so as antonia miller this is. this is the case everywhere and it's intuitive although there have also been studies with carty cells that have to be aborted because test subjects were dying and there were too many side effects

up or and. because that went out isn't that crazy. wow well by most i will say yes but we're also talking about patients who would otherwise die that's unknown with all their can comets and diseases. as our world has gotten impatient and our patients have to we're not just going to say to them let's wait 5 years and all that's the problem. that's those 4 being. the trial with these deaths didn't concern no partition which conducted follow up studies on safety and efficacy. but what do you say about no vargas's price as if in a sour soup in price i find the prices in general to be staggering in many areas and not just those of novartis. ornon these prices are completely nontransparent to patients and to us doctors or it's. someone enabling all. all of this to go on

because there are vested interests and mine so there are reasons why they want to be on the company's good solid this pushed into interestingly to whom they're stacking the 1610 film and then measure their wives stand off it because they could also produce in india or china and can afford c. and so it means jobs in basel alberts that's in the it's the jobs of course and if you look at switzerland for example it doesn't have much industry but it does boast a few of the world's most important pharmaceutical companies a 55 i can sell it. at no far to says plant in the town of dine in argos switzerland we meet with the head of cell and gene therapy in europe a month away the austrian. so this will be. this will be a key site for us. they avoid talking about

numbers here but cancer patients expect a price discount if the transport costs to the u.s. are eliminated. no says mr austin e. because the production side doesn't affect the price it is the value of gene therapy that is relevant meaning a prolonged life. this is a paradigm shift because the pharmaceutical industry used to justify its prices with high research costs. the principle of value based prices is wrong health insurers say because a human life is ultimately priceless and they estimate that premiums will rise by more than 10 percent over 10 years due to the cost of medicines. and you're not afraid that the health care system could break if you continue like this. no i'm not afraid i think we can find the solutions we are open to

take the resources the kinds we're open to take risks with with our stakeholders to make sure that we can bring the therapies the patients. the pharmaceutical industry calls this risk sharing with those insured bearing part of the risk including the risk for camera which was not even invented by novara to small. these cancer killing cells trace their origins back to the university of pennsylvania and this is far from an isolated case with more than 60 percent of newly approved drugs in the us not stemming from pharmaceutical companies right arm our german army a professor at the university of pennsylvania my team invented. in 2465 years old but i think they're working on the.

1992. karl june was named one of the world's 100 most influential people by time magazine in 2018 and the 1st actually test of this is in patients around age i.d.f. actually because they have lost during the virus many of their own t. cells. 2 years later my wife died of ovarian cancer in 2001 and so i really needed to move from a child he had to do really all cancer or at the time however he did not receive a dollar from the pharmaceutical industry because the treatment initially only worked on mice but not human it's ok for what we know for sure is that the. fundin essential a was essential to make a new industry so to have philanthropy and the government support it was

millions there was millions it was probably $20000000.00 i mean. i think for sure $20000000.00 were invested between when i came to university of pennsylvania in 1909 until nov artist of the alliance with me in 2012 but the riskiest part was state and government yes all the initial research that showed this new concept of our car teams could work with the academic laboratories in 22 and came the breakthrough in the cancer patient douglas olson however it was the news of 7 year old emily whitehead that spread around the world thank you mariah saved the young leukemia patients mind and even 7 years after the infusion she remained cancer free. the treatment is more effective in children than adults. we had hundreds of calls for a venture capitalist warning to start new companies unfortunately had novartis call

us about one of their course was this. inventing a drug is one thing says novartis but putting the research into practical use through a market launch is costly and time consuming insiders say no parties paid the university about 225000000 for the exclusive right to sell camera. and novartis is paying the university about 5 percent of the sales price for each infusion the group has no comment on this the health care industry is not transparent and it's not been designed for the benefit directly of a patient and transparency our most recent estimates. are around $55000.00 just to make the cars the cell that's our cost per patient and with no profit. so the actual cost is almost $7.00 times cheaper the university however had only done small scale trials with camera while

novartis had to fund world wide studies to attain market approval and build centers to produce the treatment. is still waiting for his cancer killing cells from the us when suddenly a message comes from nova artists the group will give him to mariah for free. plus the most mid of all the scenes were filled with joy and very rarely has it made you to be. mean you always a lot of money at stake and also of azza will start their own cult of what about other came via patients standing looking like. those i don't know novartis is a plan seemed a friend ethically it's a delicate question as to whom no barges gives free treatment not to yes of course . the 1st 2 swiss patients are being given ki mariah for free

because negotiations with health care insurers are taking so long no far to 6 planes. mikail moonshine a father of 2 children will all to lose the race against time no hartis usa informs him that his cancer killing cells have not managed to multiply well enough to produce camera. 1000 days later he dies. my name is paul tillich and then in the pharmaceutical industry for 30 years in the

last position was a us president and chief executive officer of a company i am retired now and over the last 5 years i have been dealing with a 9 curable cancer. so car know what it's like to show us all the medications that i have to take in a day. this being the most important one just as my anti-cancer drug. this product is to take one of these capsules for a day the cost of those a $750.00 each and entrusting only enough they only cost $1.00 each to manufacture what do you think about the prize the 370000 swiss francs for camera it's ridiculous car it should never happen this is a product that was developed at the expense of the us taxpayer did you have a different view when you were still

a former manager than you have now in your industry. the answer is. yes current and. for 2 reasons 1st i was not a patient i've been part of the system i've been a my family's been a beneficiary of that system. i really didn't know any better at the time you know you go to work at to get a perspective which is the company perspective and what you learn as you get older is your perspective combs much wider. than is the poem or c.e.o. of a company acquired by nope artists in 2002 he says no participants are benefited from a 50 percent discount on the cost of its trials or the camera this was the us is way of incentivizing research on a rare disease or it's people like myself who actually have funded the development program development program or half the development program of tomorrow and what we

get in return is basically a punch in the teeth from the artists. created a price model for camera based on nov artist is claims that it had invested over 1000000000 euros by the time the treatment was approved. i calculate it a fair price current all foot $200000.00 or infusion in 2019 using the assumptions using the assumption that no forests were generated total of $1700.00 patient infusions out of 14. out of 14000 potentially. goes on we can actually drop that price it can be reduced to about half of 370000 francs the fair price is calculated in such a way that no vargas achieves an average operating profit of 20.7 percent the research costs averaging at 17.3 percent are also included in this calculation the

health insurer associates. there's also demanding a price of 200000 francs for him right. i've looked at the document you sammy the document is full of incorrect information they gave me the correct information i cannot give you that and i am not i cannot comment on it because it is not ardent dhar data it is not our document the criticism on the farm are not just novartis but on the pharmacy in transparency it's growing worldwide we hear it we age o.b. hear it with the health insurers with the public because the public is the payer. are you afraid that this will damage the image of nobodies. are not afraid of the damage to the to know why it is or you mention in transparency transparency is required across the system not just from one party our government is asking for transparency because we have a transparent list for prices i think it's the opposite. or it can be discussed in

a broader group i think it's a bit it's a different conversation. 71 year old ct finding out they are also has left no cancer and he says if he has the strength he goes out with his dollars because of the price dispute he has had to wait 3 months for the health insurer to decide whether to pay for camera. quite a few could you afford it if the health insurance didn't pay when he owned approach i were 100 percent sure it would work i would sell my house but i can't sign it if it doesn't work my wife will be left with nothing that's out of the question in me that ever it is that most of us have and it's it company didn't pay for you or you wouldn't do it may know it's too risky stunt because the low chance of being cured

. and. each year around 110 cancer patients in switzerland who have undergone all other treatments to no avail receive camera and the 64 year old teacher anton schlosser in blunt maryland is one of them. if we don't have. the question is what is a human life worth it is to put it bluntly you are over 60 if a young person asks how much longer do you have left is it even worth it when curing your illness is a best case scenario and does it hurt to hear that kind of question. now you are but it don't commit now and it's so you know but i've also met young people in the hospital who are in greater need when you look at it that way. i've lived a decent life and it's been nice so far. i almost feel ashamed even though i didn't set the price you feel very uncomfortable and so guilty that it's

the only chance he has left of course you're not going to say no. do you feel guilty sure. now i didn't need billy not really i was in good health for a long time and paid premiums for decades had never really needed anything that i might be marked at the stroke this came as a surprise that i should of course. his health insurance is also paying for him right. the price negotiations between the insurers and novartis took 4 months with the price being haggled up and down like at a bazaar. some insurers threw in the towel while others came to an agreement with no artist's. insiders say insurers wanted a 45 percent discount on camera out for treating lymphatic cancer which was too much for novartis they instead agreed to a 20 to 30 percent discount to pending on camera is success rate meaning about

250002300000 francs but no one is willing to talk about. the agreement after all is confidential and fact it is so shrouded in secrecy that health insurers such as concordia which were not in on the deal will not even find out their discount huntingdale they have signed the contract because for investing kits scandalous this is the 1st time i know of for us to conclude a contract where we don't even know the price but she that's unheard of in swiss health care with prices and contract clause is a normally transparent rules but you can usually check what you have to pay for hospital treatment and cost transparency is very important in health care otherwise we subjugate ourselves to the big corporations. pending or has to have another cell sample taken because novartis didn't manage to

produce the cancer killing cells in the us as they did for me. and those who it's true of course it doesn't feel good things were looking up. it is then there wasn't enough cells at strain a cut. in the approval study for camera one 3rd of patients could not be treated at all either because the cancer killing cells couldn't be produced the patient's illness. had progressed too far or they had died waiting like mikail moonshine. can't anschluss or receives good news from the us his cancer killing cells have been successfully produced and are on their way to switzerland done because it is in one sense and then you get about these cards here man cells cells that are even stronger than normal immune cells and soon you must pass yet many moods and when immune cells get into action there are side effects last time i say sions may

experience fever circulatory problems or even organ failure. in that site at best kidney failure for instance has been observed in about 20 percent of patients once but some of them needed dialysis that just has a huge parts in andy and mattel use it as a potential most. cancer killing cells can heal patients and kill them. so those cells are the last hope for those who would otherwise die of the disease. you know michel for jerry my name is all for it scheidegger and i'm a risk capital investor day here in san francisco i'm attending the world's biggest health care conference. or invests in small biotech companies

developing new cancer drugs. have a good day about his goal is to sell the small companies to pharmaceutical companies for a profit. so. see how are you doing yes they're actually doing ok for those playability start we're doing a good bit with better mr shiner what's going on here yeah that's a shot. it's like a marriage market it's unbelievable. if you run into all kinds of biotech companies especially own political ones that fall mafia with pharmaceutical companies aiming to take over small companies later on once they've provided proof that their cancer drug is effective in humans like we're doing that it's in the. 60 percent of new drugs are not developed by pharmaceutical companies but by small biotech companies they need

a lot of money for studies with patients and this money comes from investors like alfred schott ika and marcos haasan. try to close company often invests during the early stages of research but the pharmaceutical industry pays the most when a biotech company is about to launch a new drug on the market no part of this is buying the u.s. company of texas the price sector with $90000000000.00 nearly as lions as if we did buy kites farm out for almost $12000000000.00 you know vargas is now demanding a record price of 2 point one $1000000.00 for of excess treatment is it the greasy noodles there are calculations involved that have an impact on the price tag and the fact you have to gain back your investment and of course that's part of the market price in the event based on the diet of souls from bach plays with him riaa no artist managed to avoid dealing with the biotech companies for investors by

signing a contract directly with the university saving them billions. for patient court bending or at a hospital camera is able to be successfully produced on the 2nd try. to do your futility 3 milliliters cost 370000 francs. doesn't get it this is a discussion that i frankly do not want to get into now at a patient's bedside young i've still got a life to live. i feel like i comprehend you have high hopes it will work. and tom shows are received his infusion 2 days earlier. yet said that he did this how you doing fine so i. heard it tired right i fall

asleep even if i want to watch something. next can you tell if the key roy is working on this invasive for the how it's too early we hope so of course but we can't tell through free will we have high expectations of course it's it was all i ask is me for a moment not government representative on the phone informs her of new problems with camera since it is considered a hospital treatment the cantons have to cover 55 percent of the cost. maybe a stocking doesn't know we're starting that process in parallel. by the car because of because it's a vicious circle because the health insurance only covers the costs if the cantonal government also agrees to give its part so i was in the supplies it does allow for by you know each of them says they'll only do it if the other has already agreed to the stem cut.

we meeting with jenny lee an investment banker from hong kong where she covers china that you know. china conducts the most trials on cancer killing cells worldwide and market observers say if the treatment is approved there it will cost about $70000.00 to argue the president going to get really close i mean yes there are great jenny lee says the chinese government is putting pressure on pharmaceutical companies. that for then they have to lower their drugs so the approach they are marketing is that they are a bit yeah yeah yeah because you'll want your game yes that will be a huge volume of the plot so that was all you yeah as the volume if the pharmaceutical companies read my mind those high priced really the tiniest market

cannot afford the tiniest patients are our insurance is going to sell your last loss of. heart. i also use this about profit or saving lives psalm of. fixed the existence of the existential justification of a private company is to generate profits while simple feat. and that comes before life. can't really answer that question. anton schlosser's wife documents his treatment using a cell phone. you know you said no depressed no. agitated. in the 1st days

he has fever and chills so only minor side effects. it's the same story out in social retard with court bending or coming down with a fever but otherwise he feels fine. so do you feel like it's doing a good. cover i can't say that we don't know yet there. are markers. somatic m.r.i. this biotech company is researching in the booming field of medicines for rare diseases referred to as orphan drugs just like a mariah when you say stray locations. are free to think we're focusing on morphine as an issue yet or if it's. in the us and e.u.

orphan drugs receive exclusive marketing rights with similar products from competitors excluded from approval for up to 10 years states each is all come on to tell us if the lower is built to incentivize research because once you obtain approval you enjoy a sort of exclusivity for several years a competitor can't just launch on the market that's exclusivity told to locate the greasy exclusive dates. in the us the orphan drug act was enacted almost 40 years ago today the politician who initiated it with i meant that some pharmaceutical companies are exploiting their monopoly to increase their profits. the topic of orphan drugs and market exclusivity also reached switzerland a few years ago. just.

ladies and gentlemen pursuant to council regulations before engaging in the debate on this topic i hereby disclose my vested interests i am the president of into going to the swiss association of generic drug and bio similar manufacturers. in order to promote the development of medicines for rare diseases pharmaceutical companies should enjoy market exclusivities for 10 years for orphan drugs during this period no other medicinal product should be approved for the same therapeutic indication unless it is proven to be safer or more effective. the point just for the point is pharmaceutical companies are not social institutions and they only conduct research when they expect to profit from it this out in order for new drugs for rare diseases to be introduced at all it takes a monopoly and this is achieved through market exclusivity will push the market exclusively to it because often. when sebastian trainer was voted into parliament

he gave an access badge to novartis lobbyist at the time while the artist and roche donated nearly 900000 swiss francs to the middle class parties last year and if optimistically fast still and at the end of the debate it became clear to us it was not the patients who had gained anything a through this revision of the law on thursday use your product recently that on being measured caution no but instead the main changes had been about his coffers could be filled up even though. they made him sorry throughout the commission's deliberations and still here today i feel like i and perhaps others here too i have only been aware of a fraction of all the lobbying going on here in the background of we are right on the interest since the 30 ft. calls and that had consequences. but i received a reprimand from past. then the head of novartis. creature

and what did he say. your head he emailed me because he wanted to meet with us and discuss our stance. of methadone so he claimed we were not being pharmaceutical friendly in our law making it hard to be there i thought it was outrageous for him to interfere with my parliamentary work in the parliament are the shelf that had that ever happened before i never experienced that previously or again at last. the debate went on for 2 years and the national council voted in favor of market exclusivity twice but the council of states opposed it the monopoly didn't pass but instead a stripped down measure protecting orphan drugs did. one month after the infusion with camera and touch mercer is thoroughly examined. did kim ryo work and has the cancer disappeared.

back in that yes now my i'm 1st going to show you the old pictures there was this lump here form or that there was the main mass in the fashion compartment. and of course on your lower leg. that's here it's called and now here's afterword with just some slight activity flower activity attached that there are still some in the fashion compartment but it's already received there's a lost boy place where they go. so it's mean if i couldn't have expected things to go any better you know for the hour that's the old tumor mass has completely disappeared without a trace of inflammation can you tell if he's in remission or could the cancer come back again. we don't have a crystal ball we don't know this but it's a good start. this can you can never rule it out but with kim

treatment rates with carty cells they still need more data not to quote. meanwhile in. court pending his cancer also disappeared immediately after the treatment. of course i'm glad i can get home and i'm don wearing this mosque. take care and enjoy life and use the magovern. that's the good to see. his doctor doesn't want to give a prognosis according to the no artist study it takes about one year to know which patients have overcome them phatic cancer for good. more than half die. and it's not yet clear how the cancer killing cells develop in the body in the long term. but. in this brave new world of

health care the cost of a chance at survival is exorbitant. kim riaa is just the beginning. of. what global plague is harmless to the body but is still disastrous. fake news. counterfeits on the web paralyzed democracies threaten the economy and are a thriving business who profits from them and how did they infect us song.

in germany. 90 minutes on d w. the fight against the corona virus pandemic. has the rate of infection been developing. measures are being taken. what does the latest research say. information and context. the coronavirus not doing the job of special monday to friday on w. . life on earth one of a kind and. 2 coincidences. where the improbable happened cut through the hole was going to the creation of our solar system with our planet is a bit like winning the lottery. was good for unique

starts feb 11th on t.w. . plate . this is d w news a live from berlin and more than a 1000 people are arrested in russia after the jailing of kremlin critic alexander vaulting riot police turnout in source in moscow to prevent people from demonstrating against the portland activists say that they are targeting peaceful protesters of only accuses president clinton of trying to intimidate its critics.

also coming up the fight against the 10 democrats of after advance trial show that russia sputnik the vaccine.