yes, later as a special ceremony in switzerland for middle aged men. finally, i will stand together as a linda ah, i did show up today to more world news at the top of the hour with brent golf coming up next on deep blue documentary, looking of economics of diabetes with leonardo da vinci's, mysterious masterpiece. this perhaps the greatest leonardo masterpiece in the collection of the louvre. it is the virgin of the rocks. was there another symbolic meaning to this beautiful painting? then perhaps we just don't understand today. the search for answers starts july 7th on d. w ah ah,

shrug shocked. i'd say i was shocked when i found out i had diabetes. suddenly i had to give myself an insulin shot in the stomach with ever since i was diagnosed. it is a fact in my life. i'm 29 and there's no foreseeable future for children for us in the finances. and because of my health cards less the making something over 400000000 people like diabetes stay in the world. we like to describe this as a global catastrophe in slow motion. as i've, you put together the productivity losses to put together the health care costs of medical cause it's astronomical. i mean, we know that the pharmaceutical industry is relating to diabetes and making money. wonderful. ah

ah good for the daughter she now mean if so i was born in 1963 early in february 1975. i went to a concert job. when i got home i felt tired and very weak and it's resisting. i spent the night drinking water and peeing wow the next day i did blood tests now and was told i had type one diabetes, give it to beauty, go type one diabetes that strikes without warning. musician batt handbook and that's pancreas stopped producing insulin 45 years ago. medical science has yet to explain fully why for to find the cure for

the disease. diabetes is insidious and people's lives are often severely disrupted . she's doing it again. when i get over, it showed point 81. so there's always a delay through a 2nd. i'm not thinking about the show your emotion. i'm wondering what i'll do. if i have too much sugar machine latoya, i'll be exhausted and not having enough is also a problem with will take something is sweet on stage for over there. yeah, she did is a more you debit for a type one diabetic. yeah, the injection is a relatively minor hassle in the list of inconveniences. and then the some things are much worse. you only 10 jobs a day to feel ok is fine if trees what's exhausting is constantly calculating whether you have too much sugar or insulated food. we do constantly thinking about

all those constraints you don't to trying to think ahead. the insulin you inject acts a lot more slowly than a insulin, the pancreas produces, don't you have to anticipate. there's lots of things every day that are much more of an inconvenience than shots. guarantees will be approved and presented, fulfilled. ah, the body needs certain amounts of sugar to function at different levels of exertion . even the smallest activity requires energy. the metabolic system gets the sugar it needs from reserves in the blood. if blood sugar levels become too low, the result is hypoglycemia. but

too much sugar in the blood can trigger hyperglycemia. the pancreas regulates sugar in the blood of healthy people. the oregon produces insulin of vital hormone, if this process is disrupted, the result is what is known as type one diabetes. ah, without insulins blood sugar levels rise causing organs to fail. patients fall into a coma and will eventually die if not treated. several synthetic insulin injections a day help patients regulate their blood sugar levels. ah,

as the consumer society emerged in the 19 sixty's, a 2nd kind of diabetes type 2 started to become more common lifestyles and eating habits were changing. go on, take it. all right, ma'am. people started consuming more fats and sugars and exercising less. preparing korea's had to starts to creating more and more insulin to offset the high levels of glucose or sugar in the blood. and sometimes it would stop working properly. the amount of sugar in food continually increase during the 20th century. processed meals, soft drinks and foods rich and carbohydrates were consumed and large amounts. ah, the number of diabetes patients climbed rapidly within just

a few decades from 50000000 to 430000000 worldwide 90 percent suffer from type 2 diabetes. the cases were initially concentrated in western countries in europe and the u. s. then they spread around the world 30 years ago, diaby. these was where in china to day one in 10 adults has it. the chronic disease has also spread in africa. a 150 percent increase in cases is expected by 2050 b. it's slightly of it is, isn't it just as

a forks a topical type 2 diabetes and is a classic common disease or cultural disease be out in the 1960 often had less than one percent of the population in germany was diabetic. and today it often we estimate between 9 and 11 percent before cold and diabetes hub. the disease creeps up on its victims, unannounced until suddenly serious health problems appear. law her doctor below dr . boseman. good morning. let's take a blood sample. come with me. ah . it looks like a better hum and it is a quote for conflict. the elevated blood sugar levels carry the threat of complications, but many diseases can develop. opal micro vascular problems are the main concern to

do and can occur in the eyes and kidneys by the nerves as well because they could possibly be damaged by narrowed blood vessels. who does the major blood vessels in the neck and heart are also at risk musical? that means people with diabetes face as statistically higher risk of heart attack than people who have actually already had wanted and who don't have diabetes for thought i need to refer to them. one of the most fear complications is diabetic foot and it happens when the nurse no longer function correctly. but the kind of by the feet made then no longer feel many sensations when people step on things as all, and they get wounds on their feet and leg sign. but don't notice them brucely the ice then become infected illness. and that's when the real problems that can lead to amputation began be seen to, i'm put that on food. good to dorothy. does that hurt and

diabetes is one of the leading causes of amputation in europe in the us. the disease can also attack the kidneys and as a result is a main cause of dialysis and kidney transplants that she'll spend with dorsey see me. the pharmaceutical industry reacted quickly to the rapid rise in type 2 diabetes. do you want to reach glass? i can check with lakedale to receive me. don't nice. so more lead in the 1980s, a wide range of minutes for introducing this advertising campaigns that promised a happy and care free life. deseeno guessing that then the debit little dick was here with me sometime if you wish to have it k o a whole range of pills became available to help patients lower their blood sugar

oral anti diabetics. ah, the drugs could control the disease but not cure it. patients had to take them for life, and their price kept rising. diabetes had become too expensive. communities around the world sound at the alarm, the disease caused health care systems about $760000000000.00 a year. worldwide. there is a un declaration on di visas in 2006 because of its potential to cripple any health care system. ah, because of its costs. ah, and to actually up the potential to affect the productivity of the country with the number of people with diabetes ah,

that need treatment. but there are also invalids because of diabetes and on able to work because of their diabetic complications. it is the only other condition apart from h i. v aids that has a un declaration in 1921 canadian doctors, frederick panting, and charles h best discovered insulin and made industrial production possible. the revolutionary innovation saved thousands of lives. children who were facing certain death were treated with spectacular success.

the canadian researchers sold their patent for a symbolic dollar to lily and american pharmaceutical company for commercial production. could you tell me anything about him chillin? well, he gave us how it made. well, not make it come from animal bank with the plant work day and night to supply the demand willis and use as many times the bank that each week, most of the bank that comes from abroad and arrive at the factory, deep throat, it is reduced to a paste and mixed with alcohol, which does all of the engine and then follow along complex processes which gradually remove all the impure. the manufacturing process was continually refined to day 3. companies compete for new patents, lily, the danish company, noble nor disc, and sanofi of france. human insulin based on the human

gene for insulin, eventually emerged and led to an increase in price. in some countries, human insulin can be 10 times more expensive than insulin derived from animals. it became possible to take the human instrument you should be cut out from the chromosome of humans. put the gene into a little microorganism. we use a yeast like a baker, yeast or bill yeast that we put dream in there, and then the ye, so starts making insulin. so that's called genetically engineered engine, and that means we can deliver engine to the whole world because we have no capacity problem. if we need, which is build a new factory, french, pharmaceutical company, sanofi that announced the development of a new improved and even revolutionary insulin in 2000

lantus noon as an analog insulin. it was similar to human insulins but with a modified gene. so no fees innovation prolonged its effect, but came at a hefty price in france, a dose of lantus then cost $46.00 euros, a dose of human insulin sold for 18. ah, the analog insulin reduced the number of times a diabetes would have to inject themselves to just once every 24 hours. pierre shall say over saw the lantus launch and thinks it was a major advance level. the of co launches come soon assured us united to as an insulin solution. lantus was a real revolutionary bus. children did changed the lives of diabetic patients

a cheaper especially type one diabetic who had their last injection at 10 p. m. for example, middle land then had to set the alarm for 5 am for another injection to hypoglycemia . striking in the night had always been a threat with fatal consequences at density of pastry who has any marketing. the marketing was brilliant, it convincing people, it was much slower than the others. so it really didn't slow. insulin existed in 1975 because when i only did one job a day of security, this is assuming sanofi also wanted to type 2 diabetes patients to profit from what they called their wonder drug. these diabetics had traditionally only been prescribed injections, if anti diabetic pills no longer worked go sip a cylinder to do healthily basil. incidentally, you miss it. they la down there her down there right up on for its hype to patients who were moved on to injections. it was the last stage of the nursery. they were on

death row. did you buddhism, as the simplicity of lantus lowered the fear of insulin injections man, and they began using it earlier who to host these patients were then also able to benefit from the drug flexibility of us showing a demona judicial issued inches he'll ah glucose levels in the blood or blood sugar results are too complex for non medical people to understand that's why sanofi introduced a user friendly marker with the gleich aided haemoglobin or long term blood sugar test h b, a one see mm hm.

the company started and major prevention campaign with a simple message that anyone could understand long term blood sugar levels below 7 percent are okay above 7 are problematic. a stroke of marketing genius within just a few years, lantus became a pharmaceutical block buster. in 2015 the year of its greatest sales. and just before the patent expired, lantus accounted for 20 percent of sanofi sales. more than 6000000000 euros. ah. but a doctor from germany through cold water on lantus this victory lap. peters davinsky was head of equate germany is independent institute for quality and efficiency in

health care near 30000 fear hutch with in 2000 more blunders. all the joint committees to the highest body overseeing health care in germany of tar commissioned eg, big to evaluate this insolent gorgine lantern with respect to possible additional benefits on face sister or the objective was to determine if the greater cost of the drug was reflected in greater benefits were, as if it cost the health care system a lot at reason when they wanted to know if it was justified, a mere corston dealer because ultimately every one was paying for it or not health insurers. the result was that there was no significant difference she given that lantus was not superior lunch. with medically speaking,

the analog insulin was no more effective than other drugs. pharmaceutical representatives disagreed big speak, weight loss of us could see. i'm explaining it badly. the lee of hope was if you ask a patient taking insulin to abandon their analog insulin and go back to the old insulin i dug and tell them not to worry. there's no disadvantages and it was like, it will not, many would agree yet. but my mom's always when you get a whole new when you philipo, belford sure, but she was able to lou, the statement is unjustified. but marshall too, i think it's rather strange to procure you as a dear lighter funds on north georgia for the head of senovia. germany invited me to visit the company in frankfort today to discuss the results for you that i was happy to go welcome. but at the start of the visit started me, he showed me apartment buildings where lots of people depended on sanofi for me and said, how many of their existences would be at risk if we stood by our institutes assessment

for. and because then also, nope, you workers would lose their jobs about you, robert, for you. they put pressure on you. i tried, i don't want people to lose their jobs. that's me. but i still need an objective, the valuation of drugs or not just of insolent people, but of all of them. and we don't have that one, not in any european country. kaiden, rural patient. the german authorities stood firm. patients with type 2 diabetes, using lantus, would only be reimbursed for the cost of a corresponding dose of human insulin. but so no fees drug kept selling well. sales remained high and patients grew accustomed to paying more. other countries, including france, have also questioned the superior efficacy of lantus, but nothing has changed. so no fees. block buster remains the world's best selling

insulin since 2015. so no thes competitors novo nor disk. and lily have also marketed long lasting analog insulin and they to justify the high price with attractive promises the company say that higher production costs contribute to analog insulin being comparatively more expensive than human insulin. but researchers at the university of geneva disagree. they looked at the question of why one of 2 diabetes patients worldwide has no access to insulin from its rule alleys are sooner than their actual book, a conflicts affably tear could his austrian,

you men, we were told that analog insulin is much harder to produce than human or conflict, and we wanted to know a little more about the cost of manufacture of iaa. we got together with him colleagues to determine the manufacturing cost us by looking at each section of the production line switch and the public destro. an appeal could be much help um yeah, totally madell palm yaki volkoff of retail. flipping that we took the cost of all the raw materials required for a vial of insulin. makisia, then added regulatory costs, which are significant or i'm them. regulatory costs are the expense of licensing a product to submit clinical trials are required to demonstrate the drugs effectiveness here in mouse. we also included a profit margin and the investment costs for infrastructure up love, closer to the manufacturing costs for human insulin is between $2.50 and $3.50. a vile health, flexible for most analog insulin products. and it's about the same. honda, c,

o godly plead, wrongful false valleys, all aflac when done sooner, men, viola, looking at the selling price in france, a vial of human insulin costs around $13.00 euros high school. whereas an analog insulin such as lantus costs almost double your 25 euros a vile he sion pulled. there are 3 conclusions. first, the final price for the patient or for the health care system is not justified by the manufacturing costs. the exec industrial. all the difference in manufacturing costs between human and analog. insulin does not justify the price difference in voltage and, and $30.00 plus him. the profit margins for the pharmaceutical industry on these insulin products are enormous in the local text it to know when the pharmaceutical giants dominance has tragic consequences. in the u. s. within

a decade, the price of insulin has risen tenfold. even though a 10th of the population suffers from diabetes, many can no longer afford the vital hormone despite costly health insurance policies. yeah. hello, people know why, maybe i pay a $260.00 premium a month. that's just to have the right to say i have insurance, and my deductible is $14000.00, which means i would have to pay for my insulin. and for my doctors visits and my other medical supplies out of pocket until i reach that 14000 dollar mark before they'll help me pay for my insulin. and not many people can afford to pay an extra $14000.00 out of their income every year. it's almost impossible for my

husband and right now my insulin comes from my doctor and it comes from my friends. my mom has friends that are also like maybe type 2 diabetic and they have an excess of insulin that they don't use. so they've been kind enough to give that insulin to me and my doctor when he has patients that pass away, which is unfortunately happened recently. he gave me over a year supply of insulin. so thankfully, i won't be paying that money right now because it would have been catastrophic for me if i would have had to pay the money for then swan rima ah hawkins, where you can manage to this i really don't know. i'm sorry. i really can heal, that's best thing. i've been fortunate,

not apt experience yet, but it, us sit in the back of one point. ah, my name is elizabeth, and i'm the founder of to you on international. we're a diabetes advocacy organization that takes no funding from pharmaceutical companies. and we advocate for everybody with type one diabetes, specifically access to the things that we need to survive. this company right behind me has raised the price of their insulin over 1000 percent. ah, and we believe that access to insulin is a human right. this is a global problem. people are dying in every corner of the world. people are dying here in the united states of america. what's supposed to be the wealthiest country in the world was supposedly the best health care system in the world. this is not the way that it should be. this company is putting profits over people and we're

here to say that that is not okay and that something needs to be done about it. medicines for p. o, one more time medicines for b book. oh there it truly is a crisis. people are rationing their insulin, so they're taking less than they should take or trying to not take any. they're trying to adjust their, their diet and their insolent intake. and this is so, so dangerous people are dying because of that. and they're cutting years off their life because they just simply can't afford it. my husband, i don't, in our future, we won't be able to buy a home. we can't afford that right now. we won't be able to have children. that's an expense that we wouldn't be able to afford. so i, i would say the biggest things we sacrificed is just the traditional family life. that's something that we're not sure full, ever get to experience. we've lived

a very international married life for 8 years. and although, you know, i'm very, you know, have loved our time together and it's been very hard. we've had a lot of challenges. we, we don't get to experience the things people are age, are getting to experience for the next step here is to deliver some of these insulin vials that we have created. so this is a vile of humalog with the label taken off and a message inside. what we've done is we've said these are the things that we sacrifice for the cost of insulin. i'm nicole has brought some of alex ashes that are in one of these vials to show the sacrifice the ultimate sacrifice that they made. because he couldn't afford the insulin. alec was feasting, accost at $1300.00 a month for insulin and diabetic supplies. elac work full time as a restaurant manager for

a small family owned company who did not provide health insurance for its employees . alec made decent money and because of this, he did not qualify for assistance of any kind, not from the insulin makers, not from the state and not from the federal government. without anyone knowing alec began to ration his remaining insulin, because at the time he went to the pharmacy, he did not have enough in his bank account to spend the 1300 required. alec began to adjust his diet, take less insulin than his body required to make it to payday alex body was found 3 days prior to payday. alec died from diabetic ketoacidosis due to a lack of insulin in his body. ah, at the start of 2019 the u. s. congress demanded pharmaceutical companies justify the enormous rises in price. the 3 big insulin producers blamed the us health care

system. and the large number of distributors stay the subcommittee on oversight and investigations as holding a hearing entitled, quote, priced out of a life saving drug, getting answers on the rising cost of insulin. so mr. mason from eli lilly who is making a profit from these increases in insulin prices. you know, i think you, 1st of all, we don't want any one not bill for der insulin who is making a profit with his increases in insulin prices that patients have to pay for our net prices. the parts that we receive are going down, are you, are you making a profit or the ceos of your company's making, these profits are our net prices. the prices we receive has gone down to 2009. well, somebody is making a profit, somebody's getting richer on the backs of our patients. a mr. lang from nova nor disk. what entity in this supply chain is prioritizing affordability and access of

insulin for patients. or we like to think we are, i mean we, we participated as many formulas as we can, as i've mentioned, that is critically. most important. we have patient systems, assistant programs as well as co pay system. provo is making a profit day. well our nets are going down as well, but there is a small profit that your nets but your overall, your overall profits for the company and ceo's have been going up, haven't day. no, our our profit take home pay ensemble and relatively stable from c e o pay hasn't gone up in the past several years. his pay has increased yet. okay. after the hearing, the 3 company is pledged to reduce prices for the poorest patients, but it was no more than a p r. stunt. patience in the u. s. unlike their european counterparts, are not supported by generous reimbursement systems. for most american diabetics. insulin remains a luxury item the

price of the synthetically made hormone is just one problem facing diabetics. another can have fatal consequences for patients kick to keep their blood sugar levels below the famed 7 percent limit. many type to diabetics take many drugs and by doing so, put their lives in danger of falling hobbies. tell us when they're da madigan, house at cynthia and an air yoga foxes hotel. i found out from our physician, she had an office near here. she did an annual check done and said that my blood sugar level because the long term average h, b, a one sea level was too high and that i had to take medicine days, 2 whole d miss and on lady come in could name the owner and i lived with that for many

years, but then during that time, my blood sugar levels shot up to about 11 percent. the whole young her best of is what's in when my weight was at its highest and out about 114115 kilo, it's in 100 foot of think of as well. and i need him on the tablet. and for, by the way, it was actually only just bells and variable, although i gradually took more and more of them in saline. and then i injected insulin for about 7 years. the hobby shadow, not a me as the nurse. i am not the me as early as void is done. math teacher. that was after the 1st time when i noticed that my body was shaking and my blood pressure wasn't quite right. when i measured my blood sugar, my device that i was below 60 and it was blinking, read and saying it was no longer measurable. but under 60 spies and then it came to the incident at the end of august and beyond where i nearly ended up in a coma. and oh ghost wisdom!

good luck to uh who will ship roscoe mon, full year to severe hypoglycemia, could have caused the patient his life. it was a result of an obsessive attempt to keep his blood sugar level below 7 percent in 2008. a study shook what had been established treatment protocols. it showed that the higher the level of drug consumption to keep blood sugar low, the greater the risk for patients regularly taking medicine to reduce h. b, a. one. sea levels increased the risk of hypoglycemia and heart disease. left is a phys one. it is a studio because feed me to come in from it field for me to come in from behind or the people in the study were treated with lots of medications or fashion up to 5 acres. i recall the study showed that it was probably the wrong approach. the intensive decreases in glycine me at all,

could reduce complications in the nurse and eyes house in fact. but what we really wanted was to reduce the risk of heart attacks and strokes. but that didn't happen, lawyer, and so that's why the correct approach is not to focus on blood sugar levels in the short, but rather on the study of diabetes. so now you need an overall picture of the cardio metabolic syndrome isn't with all the risk factors. and that's how we succeeded, fuck tool and bundled it when done, cynthia follicle need be okay. cindy seduction. injury possible if you could prove that she couldn't. so hyperglycemia is toxic. the evidence is incontestable. the more sugar you have in your blood, the greater the vascular toxicity schools have you, but it doesn't follow that if you have hyperglycemia, lowering the level will reduce the risk wasena. if you have a risk marker, they look the higher it is, the greater the risk cascoo a linear or automatic reduction does not necessarily reduce risk. b. major studies

have shown that trying to hard to lower glass sam yet increases risk, low quantities don't the hug selling more, less the multi, cuz he really made it so paradoxically, it's been shown that if you use intensive treatments to reduce glycemic by too much to reach a bigger as close as possible to that of a non diabetic weapon, said you might think you're as healthy as a non diabetic person. he but you're worse off than if you had left the glycemic. aha, is it not only do patients have more complications than non diabetic situations, but they have more than people with higher blood sugar magazine. they end up in the hospital with serious hypoglycemia. it's due to medication and can be severe. mortality has been increased, dissipated almost there was an email from william authentic. he hunter. yeah. i had this near coma experience and said, i don't ever want to have that again. mr. stronger. come with me. with like mit.

they've reached when i no longer takes drugs and the blood tests show that after 3 decades with tied to diabetes, a kind of remission, a retreat of the illness has said in his doctor suggested a radical approach developed by a british team of researchers. it involved a strict diet he quit eating carbohydrates sugars for 3 weeks and instead drank a low calorie, so based drink, strong weight loss is generally needed to get tied to diabetes into remission. and to find the of it us and the up along

a gloved i my diabetes in my diabetes because i know english are what's copa then that's when it was long believed that if you had time to diabetes with yeah, then once a diabetic, always a diabetic and then an english research team published a sensational studying. they went and found subjects that had been suffering from diabetes for some years and, and had them radically lose weight or she cleaners they were able to show that this could cause remission in almost half to 80 percent of the subjects. so depending on how much weight a person had lost hosea and that without a serious operation, t just by radically losing weight by should lose it is if they've learned from very in depth m r. i exams that if there's too much fat on the pancreas and then insulin production falls with the bulk. but that doesn't mean that it's broken just that the cells are no longer able to produce insulin. aagot mia ins would in if the fat is removed from the pancreas than the insulin producing cells are again able to

produce more of the hormone in response to stimulation. yes. and then blood sugar levels fall yamisha as own from it. we've done similar experiment and had comparable experiences here in dusseldorf, come into comp, we've managed to allow people who were on insulin to only rely on pills or from pills into a complete remission. and i think that's where we're headed for the future. if a patient loses weight, they can stop taking diabetes, drugs and blood pressure medication upsets and i may be able to prevent any operations. can lucas jalisa about soon from konica, lincoln fe, we've discovered a universal remedy in lifestyle. i and it works and very different areas dunphy sheet. and if you were to take all these sicknesses together and is a good lump, then you'd save lots and lots of money and food that could then be invested in this area far. hm. osmond done. it isn't, but the general opinion is that won't work. the i so we don't have to do it in gigantic. and that's a problem for politicians. and then there are the associations that represent the

pharmaceutical industries, interests, an attorney, cindy, and different one from university holla. and you have no interest in this at all. and that always makes me suspicious us and sat one day thus mark. mm hm. of it was still fishing, call with a few 1000 patients in europe in the us have already tried this method. it demands strict discipline, lots of motivation and only a 3rd of tied to diabetics can hope to be healed by it. the majority will have to continue taking medication with to post get them. and again you is looking ahead. i think we will when see the problem is knowing when says hodges is what we're saying will become incontrovertible evidence within

a few years. it printed the teachers in the meantime with many diabetics will die unnecessarily when i'm with them. some will have had more medical treatment and gosh, okay, right. and too much will have been spent pointlessly on overpriced treatments. each study showed it, but the diabetic industrial complex will be swept away like sir diabetic. going to sphere these hubby diabetes is more than just a question of blood sugar. the illness has revealed evils within the food and pharmaceutical industries. and if governments don't react, diabetes will continue to spread. mm. ah.

a conflict zone with parish banner g. russia claims it has captured the nuance region in ukraine's east eas, ukraine. losing this wall. doug walker is a former us ambassador tomato, and he believes the west should be doing more to support ukraine, but good drugs in the western alliance dealer in long term support for ukraine conflict zone. in 30 minutes on d. w. you said,

oh i and i was sexual assault survivor step to step out and say the truth. her women in asia, i pc, it's peaceable, nothing can stop me that he's out with, with this week. with

ah, this is dw news live in from berlin to night, britain's prime minister boris johnson. how much longer can he hold on to power? johnson told a hostile parliament today that he is not resigning despite a series of scandals and dozens of ministers who have quit the government in the last 24 hours. also coming up, ukrainian defense worse is preparing for a new russian ground offensive. and the regional governor of don yes is urging hundreds of thousands of civilians to flee.