ah ah ah ah, the state of the news lying from berlin, no let up in the fighting in ukraine despite a cease fire proposed by russia. heavy shelling as reported in the countries east after peeved dismisses moscow's truce announcement as a ploy to reposition of soldiers. also on the program, mexican security forces capture the son of the drug,

kingpin known as l. chapo. the operation these dozens dead, including at least 10 mexican soldiers plus hope for millions of people suffering from alzheimer's disease. a promising new drug is on the verge of approval by you as regulators. ah, i'm nichol foolish. welcome to the program. we start with the latest from the ground in ukraine, where a unilateral cease fire ordered by vladimir putin appears to be having little effect. heavy shelling from both sides has been reported along the front lines in eastern ukraine that despite moscow's claims, it would observe a 36 hour christmas truce. keith, which never agree to the cease fire, has dismissed russia's offer as a trick. skepticism was running high and ukrainian capital. as the start time of

moscow's declared cease fire approached people he and saw numerous missile attacks over the new year's period and expectations were low. oh, never foil. i think the cease fire is irrelevant as it will only be another chance for the russians to attack ukraine with missiles 3 again with elias weekly. neither you can never trust them, never. but they do nothing to join whatever they promised they don't deliver out. and they said that wouldn't be a war of you live, let say one thing one day and another the next of those. we don't trust them when it again, shortly after it was announced on thursday, keith rejected the truce saying it was a stunt by moscow to buy time to reinforce troops before the cease fire was due to come into effect. russian missiles rained down on the southern city of his own

ukrainian authority, say one rescue worker was killed and for others injured. and in the east of the country, rockets slammed into a residential building in the city of climate. hoist. many of the units fighting for russia in the dumbass said they would not recognize the ceasefire in a message published online. dennis, pushin the head of the self proclaimed don, it's people's republic roads. there can be no talk of any truce. our president's decision as an orthodox person refers to the orthodox people who go to church to attend the service on the feast of the nativity of christ and justice, the truce was set to kickin. there were reports of heavy artillery far from both sides and the eastern town of pa moot ukraine, blamed russia while moscow quickly pointed the finger at keith.

is ludmilla silver? again, is the fact that the russian military observed to cease fire to day, january 6 from 12 pm. moscow time, the cave regime continued showing residential areas and positions of russian troops like you feel as if you're worth the unilateral cease fire would have been the 1st complete loan fighting since russia invaded in february 2022. but keith says the only way to restore peace in the country is for russian troops to leave ukraine and ukrainian president followed him re zalinski as personally thank chancellor olaf shots following germany's decision to send armored combat vehicles and other heavy equipment to ukraine. the government in berlin at germany will send about 40 martyr armored fighting vehicles by the end of march. it will also send a patriot missile defense system. the decision came a day ago and what was seen as a major policy shift by berlin. russia has criticized the announcement as

a further step towards escalation and for some analysis, i'm joined now by defense. analysts have reported in brussels. he is the ceo of the political consultancy firm rasmussen, global welcome back to d, w. mr. po, t at france, the usa during the have agreed now on sending armored vehicles to ukraine. how do you see this changing the situation in the country and on the battlefield? these clearly a concerted decision by both the united states, france and germany took to cross your threshold here by delivery not made but on tanks. but as close as it gets to maine back and things like that. some things that would allow the ukrainians to operate more in walking distance areas in this house and in the us. so in that sense, i think this is an important not to say good change, or this is an important step forward to basically prepare the ukrainians for

possibly ukraine offensive control. and see that in the early spring are word vehicles and light tanks are one thing that berlin, like other western allies, is still under pressure to send, having more modern battle tanks. do you expect western allies to shift into that direction eventually? i would hope so because the reality is that for the moment the solution to this coffee is a military solution and unless we're providing ukrainians, we've longer range weapon systems as well as main battle tanks. it's unlikely that we'll be able to recover in off their territory and fleeting off the cost of the russian activities in the operational territory to be able to sit down and have a piece of negotiation that will be on ukrainian terms. so i do think this is a pretty just one step towards

a more important decisions to call. but i think it's also an attempt again, by the nato countries to give just, you know, off si fi does make a difference. and if indeed they can afford, the more i was a political decision, remember, think, do you think have a battle things could be instrumental in winning the war, or at least forcing russia to the negotiating table on ukraine's terms? i think what we're seeing since a couple of months is, is it, is it kind of sort of stalemate in the main or fraud? and at the same time, the russians having opened since detention, hooked over another method by engaging these massive rockers the size and joel strikes over the studio population of critical infrastructure. and to that, frankly, the western response has been pretty muted. a pretty strong declare issue. so we

have to adjust already to resupply strategy to allow ukrainian, again, to put an extra cost on the russian activities. and i think these things, but hopefully on the line main, but with a lot of your grants would much more pressure on the russian operation. and are to make the search for sure that the russians we see more interesting, possibly sitting down and having a more open negotiation than what they're doing. now. the fence analysts factories 14, thank you so much. thank you very much. mexican security forces have captured the alleged cartel leader of video guzman lopez, son of the notorious drug lord known as al chapo authorities say 10 soldiers and 19 criminal suspects were killed in the operation in the city of korea. cotton as cartel members trying to prevent the arrest that it is airport was even caught up in the violence terrified air passengers duck for cover rush. their plane comes

under fire during takeoff outside. cooley, a con airport and nestor ramos captured the moment to mexican air force. plain was shot at harold of my mouth. esther, i'm a friends. i'm super nervous. he and hundreds of others took shelter in the airport as the terror unfolded. the thought on the i was filming when the armed forces arrived here at the airport and they were welcomed with shots. we tried to leave walking towards a friend's house for them, but we couldn't, because they were shot into plane had to take off again in all as a silicon, dorcas parallel. unbeknownst to them, their cities most wanted man had just been arrested, unleashing a violent backlash. cart tail foot soldier, set up road blocks and waged war on the police as they try to free their boss

right below the rules of life yet. so what is being done? we have 7 state police prisoners injured. we knew that their military personnel also injured, were still working to control the situation. but oh, video guzman, lopez, no one as the mouse was previously arrested in 2019 barton, an embarrassment to the mexican authorities. he was later released after the cartel did battle with federal forces. authority see his rearranged lands, a powerful blow. she died in june for the reverse arrest was the result of 6 months of reconnaissance and surveillance work in the area of influence of this criminal group. where it was known that carried out elicit activities yet. okay. you've ok. i was like tv though this elicit us officials confirmed good man lopez

was floor into central mexico. by nightfall. he was behind bars transferred to a high security prison outside the capital. his chaotic capture, a major coup for american and mexican law enforcement. and joining us for more as laura carlson, she is the director of the americas program at the center for international policy in mexico city. miss carson, welcome to the show. there have been violin seen since the arrest of a video guzman and the city of connie o'con. what's the situation now? right now, as mentioned, there are a confirmed 29 people dead on both sides. the identities have not been released. there could be more, there are many people that are hospitalized and severely wounded in the confrontations that took place after his after his arrest. there are at least 5 other mexican states that are on alert, especially border states. that they're expecting something of a cockroach effect. or the violence to spread over into their own states or taking

measures as well. it looks as though most of the road blocks have been lifted according to local reports, however, it's expected that the violence will continue. we know this because of the pattern of violence in other situations. similar situations throughout the history of the war on drugs here in mexico. when a drug lord is taken out in what's called the king pin strategy, there's almost inevitably an uptick in the violence both localized and eventually on a national level as it causes a fragmentation. re mobilization of the car tell it causes turf wars. and so we're actually expecting that there would be more violence to come. he allegedly helped run the snellville cartel for his father, al chow opposed. of course serving a life sentence in the us sinaloa is the world's most powerful car. tell how big of a blow is guzman arrest for them. we have to put this in the context. first of all,

it's very important to mention that a video guzman, the son of chapel, is not a major leader in the seen a lot cartel and the senior law cartel now has major rifles. it doesn't have the, the hedge a monic strength that it had in mexico in the past. and so this blow on the level of the cartel hierarchy is not the highest ranks of the cartels. he's not the one who was calling all the shots. in fact, his older brothers are really in a far more powerful position as well as other leaders that were left within the similar cartel. so in that sense, we don't expect to see an immediate dismantling or weakening of this in a low cartel. in fact, when we look at the overall effect of an act like this of the rest of the video guzman, we expect it to be negative, negative for public security and safety in mexico with no substantial

or perhaps even none whatsoever. effect on the flow to listen drugs to the united states. and this is simply because this war on drugs model of taking out the drug lords, while leaving the structures, including the huge demand in the united states in place, doesn't work. it never has worked anywhere. and certainly never worked in mexico since it was launched at the end of the year, 2006. and so we really are many experts. and those of us who have been studying this issue for years here in mexico are not expecting a positive outcome from this arrest. unfortunately, what do you make of the timing of this arrest? because joe biden is set to visit mexico in a couple of days. i think the time is that is everything. the secretary of defense mentioned that they've been working for 6 months on intelligence, but everyone knows where oh, video, whose man was he never left since his arrest in 2000. and 19,

what we're seeing is that the, the arrest in 2019 was actually a success he was captured. and that was the mexican government that made the decision based on a calculation of widespread violence and the cost to the civilian population. to let him go, the decision in retrospect was a good. what if you're putting priority on human lives rather than on this cat and mouse game between the cartels and the u. s. and mexican governments over the past years, which as i say, as lead to no positive outcomes either in the, in the trafficking of illegal drugs or in public safety in either one of the countries. so this was a timed to be really a gift to joe biden. presently, joe biden has been a drug or promoters since his role as vice president. he has rejected public health solutions to the problem of illicit drug use and traffic in. and he

has, he's the architect of plan colombia, and he's been very firm in enforcing the same model, failed model in mexico and in central america. so the mexican government can now say, see, we're not soft on these cartels. we captured one of the persons who had been to be at a $5000000.00 reward on him from the state department. and they'll be able to use that as leverage and some of the other negotiations. but it's not a good calculation for the populations themselves. and are across and says that this is for show, but it won't change anything. thank you so much. joining us tonight from mexico city lar, coughing, thank you. all timers disease effect tens of millions of people worldwide, and that number is expected to rise as population's age right now, they're next to no effective treatments for the disease. but that could soon change

a promising new drug developed by japanese pharma company i psi, and u. s. biotech firm biogen may get accelerated approval in the us as soon as today. also labors disease was 1st diagnosed and a woman named august. they tear over a century ago. it's the most common cause of dementia. in general, expect it to a 3rd of all cases are due to all times to see. but for a number of reasons, cures, or even adequate treatments for all timers have proven, stubbornly elusive to has been a taboo. people didn't talk about it. second on the funding, we have $15.00 to $20.00 times less funding for this disease area. go back to cancer, also we have equal numbers about 5055000000 in the world. and 30, it's very difficult. this is a brain disorder and that the most difficult organ of the body has all timers.

disease progresses, clumps of protein called amyloid form in the brain of the affected patient. another protein called tao, which usually stabilizes neurons instead begins to form tangles like those here in blue. that also plays a key role in degeneration. there is a picture and metaphor for that, so the emily pathology is the trigger that of the gun. but finally the bullet that killed suddenly top of the g mckenna, mab. new old timers, treatment slows, the formation of plaques in the brain. it's an artificially produced antibody that works by binding to amyloid the medication has broken new ground in the field. this is a big success. and so this is the 1st, this is the 1st trial with the proven result in a phase 3 clinical trial. i think the science is har. fair and so,

so this is opening the door. i would say it's a milestone. it's definitely a very important milestone because it's the 1st druck that it is not acting soon. symptomatic lee, it's clearly deceives modifying and the circumstance that showed in a face free trial or positive outcome in all i'm really and secretary what's the kind of map only slowed the loss of cognition. it didn't halted completely. still. it's a promising step towards potentially stopping or even curing this debilitating neurological condition. nick fox as a professor of neurology and director of the dimensional research center at university college london. welcome to the w professor, what can that new drug deal for patients and what can it do with her exciting time for field? this has been a long time coming long time. hope for this is really the 1st time that we are seeing both the disease being modified in terms of changing the underlying

pathology. i'm a lawyer was removed from the brain of people in the trial and showing clinical benefits. so perhaps the talk of the list of possible benefits is hope, hope for patients who up until now had no chance new prospect of a disease being slowed. i think that's really important. what are the limitations? because this is, this is aimed at early stage patients only isn't it? absolutely. so it's, it's, this is not a cure as your piece earlier. we're saying it's it does slow the disease. if we look at the clinical markers, it looks like it's slowing it by about a quarter. now that's not not a cure, it's not a halting disease, but it's very important. and what would be really important, and we don't yet know is this trial was 18 months long if this benefit was cumulative, and sustained so that you get that 25 percent or whatever,

slowing year on year. that is a really significant in terms of number of, of years of quality life that it, that is retained. there are major, major challenges. it, our health care systems are not geared up to provide these were intravenous infusions given every 2 weeks. lots of brain scans for safety, and people had either a lumber punch or a particular def brain's going to look for amyloid before they started. this will really be a challenge to our health care systems across the world. even the most privileged societies. and there are risks right, there are serious side effects. there absolutely are risks and side effects, as with all biological reactive therapies, as we've seen with cancer, another therapies. these effective therapies often have ris. we will have to

counsel patients carefully about the risk. and in particular, have cautions about what other therapies we can use at the same time as using these treatments. according to the w h on demand as a leading cause of death globally, yet only 1.5 percent of the global health research is focused on the disease as an expert in the field. why is it so under funded a lot of reasons. i think a part of its historic about dementia had a, a, had a both, had a stigma in the way that cancer came out of the closet many years ago and dimensions taken longer to do that. there was of neil is in the sense that this was too difficult of these brain diseases. a difficult near generation was particularly difficult. this would be too difficult. it's not had the sustain funding go to other areas of medicine, half had and those areas have revealed that previously incurable thir diseases h i v aids some kansas could really be slowed and in some cases q

and we have to hope that's what we will see in dementia ne fox, professor of neurology joining us tonight from london. thank you. pleasure. ah, i'm for sports now and the lose world cub returns from a break this weekend with a stop in lithuania. so far the season, germany's traditional dominance has looked like a thing of the past due in part to the departure of german lose legend care hacker . he now works as a coach for the austrian team and has big ambitions with his new employer. no longer a german lucius, drawing to success like their once used to one of the missing ingredients is gill cockle. as an athlete and coach, he spent 35 years keeping germany at the very top

hospital, 13 olympic medals of his own. and as a coach saw, as athletes claim 11 last summer saw hackles had to austria having finally decided that was time for a change in the motion. y'all look it up on our ascii, some packing. a whole package was so interesting. as in that i was happy to go for it and harvey and take this last chance in my life to try something new in my career. then again, morgan, i'm in health. in the workshop hoc hollis always pursue the new. his reputation for technical innovation is evident in his nickname. the loose professor is, is a model, ea, it's the arrow dynamic form which has to merge with the luge is body and complimented to cancel to some intrusion was it all comes down to the blades,

the sensitive point of contact with the ice, the price tool of any loser, they are the subject and result of hours of meticulous care. the style accountant there, cool from the seo edges of the blades, have to be so sharp that they damage the ice as little as possible. an ice you through so that way the sled tank lloyd but still gives enough support that you don't start sliding around from side to side during the run. it all sounds easy in the words of the loose professor. but a look at this time table offers a glimpse of his toss true complexity. looking all the way ahead to the 2026 games . he and his team austria colleagues are out to finally gain viet over the competition. thing with winters sports has been an unseasonably warm winter so far

across europe, causing plenty of frustration for fans or resume in the czech republic is one of the many ski resorts around europe that has been brought to a standstill. some piece and neighboring areas have only been able to open things to artificial snow. the weather has also disrupted the sporting calendar with skiing world cup events like this one in croatia in called off due to high temperatures. now earlier we spoke to professor robot caspar from zebra castle university in south spoke. he said the international olympic committee is already acting in the face of environmental challenges to 20 games. but let us take the, i'll see, i'll see her for the past 2 additional for 22 and 26, only seen to candidate cities and they have changed their entire process of bidding . and they are now discussing permanent host the cities for the olympic winter

games. they're opening up for parties centric bits. that means olympic games across various countries and reducing the capacities in the venues that is for now. but stay tuned for our environment. magazine eco africa, this time with a look at the demo. fueling unrest. endless though, i'm not really sure. thank you so much for your company with ah, with

who know last can inspire big changes, meet the people making people go africa. joined them as they set out to save the environment, learn from one another and work together for a better future. ah,

many thoughts do you all for choosing it for go next on d w. o. oh, i was making the headlights and what's behind van d. w. news africa, the show that the issues have been the continent. life is slowly getting back to normal here. where on the streets to give you enough reports on the inside of our cars, funding is on the ground reporting from across the continent. all the french stuff, the mazda u. t. w is africa every friday on dw. oh, the question over more questions about the life, the universe and everything,

to you the answer? well, in give it here. he took the answer to almost everything. in a word document 3 series with clever crazy ground breaking questions can legalize the after life or are we getting dumber? how can we feed every 1? 40 to the answer to almost everything. starts january 15 on d, w, a dot a hello and the one welcome from nigeria. it's nice to have you with us in this new edition of echo africa. then var remain to show brought to you by d w.