so that's how she thinks most rain, so today lives mother, annoyed for nearly 4 decades. she's for peace for me, for brace of freedoms in your home, then the run in spite of fall, very tries on our children should not inherit science from us. the an income if you look into him, nice thoughts, july 29th on w, and the courage bridge wasn't on drained and back in 2018. the 1st vehicle to cross had none other than vladimir putting behind the wheel. it was an easy europe's longest bridge, and one that stood for putin's aims to permanently ty ukraine, or at least the parts of it, he legally annexed in 2014, through russia. the symbolism is huge and so is it strategic importance?

it is to this day, the only bridge connecting the crime in peninsula and the russian mainland, and serves as a crucial supply route for russia's military. and today, it was partially destroyed for the 2nd time in less than a year. you create and want it to damage an emblematic reminder of russia's invasion and had put in where it hurts. on the call for lucian, berlin. and this is the day the system to this morning started with the news of the emergency that happened of a crime in bridge. but then they went into the sections of the bridge was damaged as a result of a terrorist act committed by the special forces of ukraine.

for some reason, we asked for traveling lives and residents of the convention and not to go to the crime in bridge, but to use alternative land routes. initially, our response will be to achieve the goals of a special ministry operation. also on the day, the death of a young woman after being detained by a runs morales, the police sparked nationwide protests. now the patrols are back seeking to impose these law, make republics strict dress code on women. a good thing. the morality police can prevent women from not within their hytcher. they cannot enforce it like before. the number of people who do not be too high, now. they cannot 100 or the phosphate. i'll come to the show. the strikes came and the dead of night, 2 explosions have destroyed

a section of the courage bridge. russia claims the blast killed 2 civilians and brought down a section of the roadway connecting russia to occupied crimea. when it was inaugurated president vladimir put and lead a convoy across to mark the event, the bridge is the most potent and most hated symbol of russia's occupation of premier. the territory moscow annexed illegally from ukraine and 2014. now the bridge has been damaged for the 2nd time in 10 months, that cuts the main supply route for russian troops fighting and southern ukraine. that is another blow against moscow's forces. still reeling from a mutiny last month. but she was ready to cry me uh, damaged once again. this footage released by moscow shows russian investigators picking through the debt break. at the traffic on the bridge was suspended. moscow says 2 people were killed. and what the russian president described as a terrorist act by the ukrainian government is

a direct the roadway on several spans of the crime near bridge was seriously damaged. both road and rail traffic were temporarily stopped with their line waiting for a concrete proposal to improve the security of the strategic, the important transport infrastructure that's talking about being constructed in 2015 after russia annexed the crime in peninsula. it's a vital supply line full must go to access illegally held ukrainians, have a treat as the bridge was 1st attacked in october last year, the cranes government place that suggested it was behind the attack. there never claimed responsibility with rights n k many ukrainians welcomes the latest the souls of the bridge know which of will at least it will be fewer deliveries of women's and provisions. and that might, we can learn when they are supposed to loveland which just took. so yes,

it's uh helping us, i guess, a little bit, not so much when they, but they will be angry and attack ukraine. haul the most of it all. they are capable of this, and this one is the most guy has said it is racing to repair and we already put in the bridge that's by strategically and symbolically important to russia. dates claims a crimea cruise walker is a former us special representative for you. frame and a former us ambassador to nato. welcome to the day, mr. investor. let's start with the attack on the courage bridge. what ways heavier, hear the psychological impact or the military advantage? so, well, i think it's a combination. i do think it's important for ukraine to be able to knock out the ridge completely. it seems that they were able to take out the road lines, but the rail line may still be functional. so they'll need to go after that one more time. but it is important to disrupt the russian logistical supply chain that

is feeding and supplying the troops that are in crimea and southern ukraine. sort of logically, for russia, i think it's important, i think what will be even more important will be breaking the, the land line of communication, the land card or that can ex rust of the in southern russia to crimea. ukrainians can break through that. it was certainly name there currently is cut off, and that i think will have a strong psychological impact in russia. ukraine and officials that have been quoted, i'll be at anonymously saying they were behind us attack. they're usually a lot more opaque about these kinds of operations. what can we read into that? well, 1st of all, i think they are trying to avoid taking direct responsibility just to create some kind of mystery. now not being clear about how exactly it happened, but i think we can be very confident that it was in fact ukrainians that did this. uh, these bridges don't just follow up on their own. and in addition,

i think the ukrainians feel a little bit of pressure to show that there are results from their counter offensive. and the movement on the ground has been slow. and i think that's one of the reasons why they're a little bit more open about taking credit for this to show that they aren't capable of taking down the russian forces. yeah, let's look at this counter offensive because after last week's nato summit that i'm wondering if can, you've can really be assured that the support from his partner will not depend on what you are just changing at fast battlefield success. yeah, i think the we are in the clear for a while still we have strong bipartisan support in united states republican and democrat, both houses of congress, the white house, i'm sure that we will put through another supplemental agreement or supplemental budgeting package that will give us funding to help you brain drill all of next year. so i think those things are likely to happen. that being said,

i think the administration itself is a little concerned about if the, the conflict becomes really a fail me. then what do they do? do they continue just applying the weapons and, and not seeing much progress or is it time then for to push for some kind of negotiation? ukrainians, of course, are very much against that because they know that russia is not going to give up any territory in negotiations. they want to keep taking more. they're your brains are concerned that there's going to be some rob blueness on the western part. yeah, and talking about wobbling us on the western part, the nato summit. last week. i want to share something with our viewers that you wrote about it. because you said that nato not giving you create a roadmap for membership, reflect a failure to understand that the nature of european security has changed. you said ukraine is currently doing nato's job for it, fighting to defend the frontier of a free europe. it's more capable militarily and most allies and defending the values on which nato is founded. russia is attacking ukraine because it seeks to

defeat those values. key remaining stuck in the needle, waiting room is a green line for improvement to attack. again, that tell me mr. invested or how dangerous could this stalling technique become? not only for ukraine, but for all of your swell. exactly, it is dangerous for all of europe. for a long time, for 70 years, we were able to defend the borders of nato territory and not worry about the outbreak of a large war in europe that would impact the security of nato countries. that's no longer true. we have a war in europe right now, and it is impacting the security of every natal country and many countries outside of us. we're seeing refugee flows. we seeing the disruption of energy supplies, massive insulation, and so on. and tremendous economic and defense cost of motor hours. so this is no longer cost free. so today what needs to happen to the end of it is where you're going to be admitted to the alliance and

a firm border establish with russia yet again. that was the thing that establishes and security in europe in the long term. that means in the near term, we have to signal that this is where this is going and help give you credit what it needs to win the war as quickly as possible. those are the things that would cause bruton to start to recognize that he will never succeed. if we don't do those things, if we have this vague and as soon as wobbling this, it encourages prudent to keep the war going. so why is the west not doing that? what is behind this reluctance? some argue that having ukraine and nato is even against the national interest of countries like the us or germany. yeah, i think it having the ukraine, i mean ukrainian nato is very much in the us in german interest. it will stabilize security in europe. we will have clear borders again in the future. we will have one of the most capable countries in europe, militarily, one side with the rest of the alliance. i think all of those are great benefits,

but it could all work, drag nato into a major conflict with russia, and that is something the lines is of course, seeking to avoid. that's correct. so that is why i think leaders don't, is politically us and germany did not want to say anything stronger about ukraine coming into the lights. we made it very vague, implied the allies don't agree on this and they apply that. there are some conditions that have to be met, but they didn't specify with those are, so that was a very weak signal coming out of the building the site. and the reason is, just as you said, they didn't want to create an impression that nato was in a conflict with russia. it's only ukraine defending himself against russia. they also are concerned that russia has nuclear weapons. and that's one of the reasons why they don't want to the image of being in a conflict with russia. problem with all that is the russians itself, in conflict with the west already. and just look at the number of things that

russia has done, whether it's assassinating people on german or british soil, whether it is shutting off the energy supplies to europe or trying to use it as a weapon. webinar using refugees and immigration. all, all kinds of things that are a threat to europe from the west opposite from russia. that treatment continues to do right now. so we're not, we're not fooling the russians or we are not keeping ourselves out of any conflict . simply by not saying that you drain has a pathway to membership russians already see it as that current hawk or special representative for ukraine formerly. so and a former us ambassador to nato. thank you so much for your time. thank you. and around showing hair has become an act of defiance. ever since a wave of protests swept the country last year after

a young woman died after being taken into custody by the morales, the police for allegedly not wearing her huge job correctly. going out without a head scarf, became a political statement. note that there was a note of the oppression. in the midst of the social uprising, the religious police had largely pulled back. but now runs leaders, say the patrols or back and we'll enforce the as nomic republic strict dress code. but many women say they will not be intimidated. there's plenty of hair on display on the streets of a rod's capital to run while women are blinds to wear a headscarf. the young generation in particular, is spoken to defying the rules of the islamic republic. now the door teeth are hating back police as the own majority from today. police patrols will be established throughout the country so that i know in addition to the other duties,

these police officers will deal with those who unfortunately ignore the consequences of not wearing the property. he jed and insist on decided buying the norms on bad hon. georgia, can you throw that on here on street at morales? the police are set to patrol the streets again and you pushed forth women to add that he job despite their reputation for brutality. not everyone is willing to have that looks policed. the good thing that morality police can prevent women from not within their who job. they cannot enforce it, like before. the number of people who do not be too high. now, they cannot 100 or the 5 stages that the last thing they can do is choose the violence enforced against us of the morales. the police have been lying low since the deafening custody of $22.00 a. alt do not mazda, i mean, he arrested last september for not wearing her head stuff. the incident spot months

of protest, vinyl track down. that was only the 500 people killed and 20000. the rest is now that the protests have died down. the last concert of latest reasserting though, sorry to on public life. and for more on this, i'm going now by my whole time, mary margaret, i'm, he's the director of around human rights space in oslo. mr. and we're in walking down. welcome back to the double, you know, can you tell us how the ringing people have been reacting to this renewed attempt to force women to wear this woman cut square? well, and thanks for having me here. and you see a people in the wrong, they know that the rundown of authorities are doing whatever they can at to get prepared for the 1st anniversary of the nationwide protest. and in the last 10 months, they have managed to have control over the cities so that you haven't had the big

protest. we have had focus in the corners of the country in baluchistan in particular. but what they haven't managed to do is to control women. so number of people who are being a blocking out in the streets defying the rules of these comics republic have been too high. and what they are doing now is trying to get control before down the grocery. do you believe they will succeed in pressuring women into wearing the headscarf into covering up into effectively disappearing from public life again as well. and you see the are dealing with the regime that doesn't belong to the, our time, you know, we have the gender apartheid, half of the population have to do what the, if you, who are really in the country say. so these kind of system cannot survive for a long time, but they have money so far because they use extensive force, you know,

besides more than 500 people who are killed on the streets in the last 10 years, about 600 people have been hired and continued on execute at the 7 of them are a protest theirs, so they do whatever they can to extend their survival. but they can continue forever. i read it. i'm surprised how international community and how to board tolerate that in 2023 women are treated as 2nd class citizens. they are, that regime uses force on then to make them we are of what they say. and they are still part of the international community and they are sitting in the chair. my sheet buffer is humor, right? you and human rights concepts associated for them. know, what should the international community do in your opinion, or this should not be tolerated. you know, we international community to then tolerate the racial apartheid in south africa.

it's as easy as that. this, the way they are treating women should not be told the right that eh, you run and politicians are traveling. they are meeting with their west and counterparts. that should not happen. i mean, is it comp accept the better for the world today that human beings just because the a women are treated the way they are doing doesn't have any consequences for the reaching faced with this lack of international pressure or sufficient international pressure. do you expect to see your resurgence in protest following the announcement of the crack down even before the anniversary of the death of geno mazda? i mean, you know, eh, new pro peace can come at any time because it's not owned, as oppressive regimes. it's also a highly incompetent and corrupt regimes. they are not able to solve people's daily

problems, financial issues. so it is just a question of time at new put this can come at any time. and this is why they are trying to spread as much fear as possible amongst people. so that the next part, this will not be completely out of control. but i'm sure that you put this way. come, i was very involved with that most around human rights joining us from also thank you so much i. let's imagine not recognizing your spouse not remembering your child's name, not knowing how to take care of your most basic needs. that's a painful reality of millions of people around the world living with alzheimer's. now us drug maker, eli lilly says it's experimental drugs done on a mom can slow down the development of the disease. patients with the disease will

inevitably deteriorate, but the company says that process can be delayed by 4 to 7 months. eli lilly ones, the federal drugs administration to approve its product. they have da turned down a request for early approval earlier this year and demanded further trials. the company says those trials show that drugs slows, the development of alzheimer's and 60 percent of early stage patients, but also reported significant side effects. let's take a closer look and bring in the eric rivera. he's a professor of medicine and clinician educator and the division of geriatrics at the university of california in san francisco. she also wrote and editorial published alongside that eli lilly report in the journal of the american medical association today. dr. vidara, welcome to the day. now people obviously want a magic bullet to treat outside morris. is this it a small step forward?

um, and it's gonna take a lot of small step forwards. what we're seeing with this drug is it's not a cure. it doesn't reverse dementia. so if, if you progress to the point of, for getting people, it's not going to get that back. what it does is it slightly lessons the worsening of technician and function compared to placebo. when you get this drug with a caviar, there's also some significant side effects with the infusions of these drugs getting really expensive cost. we saw some depths associated with treatment and there's other issues like rain bleeding with this and fusion of the drug. it's something that we talked about during the pandemic. if the risks out way, the benefits. what would you say in this case, we're talking about swelling of the brain. mind crow bleeds, should people still go for this and should be if they approve the strong? yeah, so um they, they approved a very similar drive with very similar outcomes called la, can't imap so i don't see

a future where the fha is not gonna approve this drug. and i think you're right, it's all about this balance of benefits versus risks. and the benefits that we're seeing, you know, the primary outcome, what they looked at, it was a 144 point scale. and when you looked at the cbo versus those who got the drug, you saw a 3 point difference in this 144 points. so i would say it's, it's a small difference, how clinically meaningful of that, i think is a big question to debate. but we're also seeing other things like less people progressing to the next stage of use, which for me matters more than kind of the scale. so that is helpful. well, that's out again, small differences the, the big concerns is that a, you have to, for this drug, you have to go and basically monthly, which really can't about the other drug. you have to go in twice a month for an fusions then fusions looking at fusion reactions. these drugs also seem to cause micro bleeds in the brain, but i can call also cause these bigger basically it's and we saw 3 depths with this

study was similar, 3 deaths with academy of study, another one of these emulated antibodies studies. and you know, cost is going to be a big issue including cost to the health care system, to medicare and also cost an individual patient. because there will be co pays for many individuals, which will put this drug out to reach as it's probably going to be marketed similar to the catamount somewhere around $25000.00. just for the drug, not for the infusion. multiple m arise, the pet scan. so this is going to require somebody to really be able to work closely with the health care system to get all of this stuff. and the biggest issue too is, is that for a lot of individuals, they may live too far away to one of these centers to actually have access to it if they want to do it. and that's a big yes, because there, this is not a silver, but there's not a drug. i would say absolutely. yes. you should get this if you have mile cognitive impairment for jerry, for really awesome reviews. it's a clear know if they have moderate or severe all services use,

but it really warrants a discussion with the health care provider. is this going to help me more than it's going to hurt me? this is not the 1st drug aimed at removing deposits of protein from the brain of alzheimer's patients. are the researchers on the right track here and your opinion, or are there more significant factors that can then maybe show more promising results? yeah, i think i think the strike this trial tells us 2 important pieces of information. one is there is a big debate about whether amyloid the m or would hypothesis is, is real. this is the thing that we should be targeting. is there any evidence that it works? this drug and le canada have both show us that there's something going on there seems to be this effect. it's doing something, although that effect also is really small. this drug is exceptionally good at removing m a lloyd from the brain. now if it was just them or that was causing the problem, you'd imagine people do a lot better than is very, very small changes that we're seeing on these like 144 point scales. and that may

be because we're targeting the wrong thing, or we have to target multiple different things, which is probably what we're going to do. maybe it's similar to cancer drugs in the future where you have to do multiple different things. or you may find out a whole new path would be better than this animal. lloyd targeted eric with era of the oh, sorry, yeah. testing one more thing. yes. we only have the data for the 1st 18 months, so we actually don't know what's also going to happen 3 years down the line. and there's some concern because of these individuals who get the drug have more brain atrophy. what does that mean? 34 years down the line, so we definitely need longer trials assessing the advocacy and safety of this drug . all right, so you would say there are too many question marks at this point for approval. i would say that it's likely to be approved because we have the same question marks

with what can't imap which got after you approved. i think this requires a very good discussion about risk. some benefits if you're going to start this drug . i think we know now that drugs probably going to be in the wild sometimes for the health care system is not very good at that. so we'll have to see what actually it looks like in the while. we'll have to leave it here. thank you so much, eric. we're there at the university of california in san francisco. thanks for having me. a mess our time. so make sure to turn in again tomorrow by the

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