there. this morning with an interview with the virginia television station, wvay, the president was asked, will, he apologize and here was part of his answer. he replied: no. we will not apologize, mr. romney claims he's mr. fix it for the economy because of his business experience and voters entirely legitimately want to know what exactly is the business experience and as head of a private equity firm his job was to maximize profits and help investors. there is nothing wrong with that but he raises questions about the potential outsourcing of jobs during what he says was mr. romney's tenure and term at bain capital. and, mitt romney denied the accusations and acknowledge he was a sole shareholder of bain capital for a brief time until the control was handed over to a group of partners, so the rhetoric on the campaign trail, heighting up with the president refusing to apologize, we'll

have a lot more on this coming up in our political segments in the next hour. ♪ >> jamie: time for "sunday house call," joining us this morning, dr. marc siegel associate professor of medicine at nyu's langone medical center and the author of "inner pulse, unlocking the secret code of health." >> and the chief of robotics at the mt. sinai center in new york, dr. samadi, good to see you. >> jamie: good morning, i'm particularly excited about the first topic you brought us, because so many people know one who has alzheimer's, they really love and care about and for the first time, researchers discovered a gene that may actually protect folks against the degenerative brain disease. dr. siegel, this is exciting, isn't it? >> its so important because we thought for a long time, a protein, beta amyloid which builds in the brain of people

with alzheimer's patients, remember the word, beta amyloid, it clogs the nerves and, 5 million people have it and probably more undiagnosed, beta amyloid, by the time you see in the brain is too late to do anything and there is another m enzyme, amyloid precursor protein, and it causes the amyloid to form and and a study out of iceland found if you have a mutation or change to that protein you don't make the amyloid and guess what? you have over a 7 times less chance of getting alzheimer's. 7 times less and they studied it in over a thousand people and it was very convincing. for all of the new drugs out there, targeted therapy, antibiotics targeting this amyloid there's a lot of success, possibly on the horizon. we're looking at now how you block the gene. how you get the same thing, in the rare segment of the population, it is very rare that

you have the mutation. >> jamie: let me ask dr. samadi, i want to start it now, whatever it is. can you do anything right now? >> well, it is not ready for primetime. and this is all at the level of research but the big question, jamie, is, you look at someone with -- an 80-year-old who is absolutely functional and is doing well and is, woulding and another 80-year-old person is completely nonfunctional. why does that happen? and it goes back to what marc was trying to say. there are genetic differences between all of us and that is what we are seeing. we talk about plaque. what exactly is plaque? the same plaque that sits in the arteries and causes a heart attack, same kind of plaque can go to the brain. it is a different type but the same concept and, the information from one side of the brain doesn't get to the other side and what does it do? alzheimer's, what we have to do. most of the studies, and the big news here in alzheimer's, is, we're making it very -- a very small step forward in the field that has robbed the brains of the population, 5 million

people, how do we do this? prevent the plaque from forming or wash it out when it is formed and i think what the definition is here, the antibodies can clean it up and it is really at the research level and we have a long way to go, and, as you said, it is a devastating problem and we see it on the human level, a lot of people forget their addresses and are coming back... >> jamie: it is awful. >> the big news not part of the article, the imaging part of it, the pet scans and images are able to detect the plaque much earlier and, perhaps, you can do something and i guess, in the past we talked about the victim b-12. if you don't have alzheimer's and you may have a low deficiency of vitamin b-12 it is a way to check out -- >> eric: you should check vitamin b-12 now, go to your doctor. >> absolutely. it is great he brings that up and brings up another point, it may not be alzheimer's. if you have dementia you could be depressed, a b-12 deficiency and mini-strokes. and before someone puts the disease on you, the name, get it

checked by a physician. >> eric: talking about the brain situation and talking about plaque, did you know every two minutes in the country, someone dies from a neurological emergency? now there is a new device they say that could help save time and lives and it is amazing. what is the new device, are you talking about aneurysms and strokes? >> seizure, before i get into this, he promised by the end of the year i will be board certified internal medicine, talking about all of these medical issues. >> i'm getting a urology degree here. >> and we talked about seizure and the whole change in the electrical activity of the brain and i don't know if you saw anybody that had seizure and i have seen a couple of times and it is scary, you are next to somebody, the last time it happened i tried to get a soda and the person next to me fell and had a generalized seizures, which is really scary and the first thing to do, if you are the only one there. not to panic and try to basically stable their head. the first thing they want to do,

they bang their heads and, they can injure themselves and turn them to the side and make sure they are not aspirating but the treatment is to give in the iv infection of something called lorazepam. and, how many people walking around with this iv -- if you have it how do you put it into someone with a seizure and now like the epi pen for allergies they have a large scale study of over 70 hospitals, 4,000 paramedics, that if somebody is having seizures, you can just give them a quick injection and, 73% of the time. they are fine. >> eric: epi pencs, the doctor says, if you have allergies, carry it. if you suffer from seizures will you be able to carry the lorazepam. >> it is -- we use it in all kinds of procedures. the first thing about seizures, is to get medical professionals

on the scene. if you are having a seizure it is not a do it yourself situation. you want to call 911 and want to get an ambulance there, but the study is interesting, it was done in a thousand patients and it is what we call a randomized double blinded study and we love those, it was done really, really weld. and it shows that instead of giving it intravenously you stop the seizure better if you gave a shot in the arm, intramuscular injection, is probably the way to go and in the future, as you point out you may be able to do that yourself but now you are not ready to do that yourself. this is an instruction for ems, an instruction for an arriving ambulance, give them a shot and if you don't stop the seizure, status epilepticus is the term, 5 to 30 minutes there is a fairly high chance something bad can happen and your brain can swell and you can have a problem with your nerves, up to 20% death rate with that. >> eric: certainly hope we get that onto the market soon. >> jamie: the concept is interesting and there's a

stunning report as well, parents, you want to know how the media is influencing our children? what is driving a large number of kids to do? we'll tell you about that one, an important note for parents. next. [ buzz ] off to work! did you know honey nut cheerios is america's favorite cereal? oh, you're good! hey, did you know that honey nut cheerios is... oh you too! ooh, hey america's favorite cereais... honey nut cheerios ok then off to iceland! ♪ ♪ [ male announcer ] we believe you're at your best when you can relax and be yourself. and at thousands of newly refreshed holiday inn hotels, you always can. holiday inn. stay you. and now stay rewarded with vacation pay. stay two weekend nights and get a $75 prepaid card.

constipated? phillipscaplets use magnesiu an ingredient that rks more naturally with your colon than stulant laxatives, phillipscaplets use magnesiu for effective relie of constation without cramps. thanks. good morning, students. today we're gonna continue... ♪ >> jamie: imagine what it is like to be a kid. and being pressured to diet, just to fit in with the media's aimage of what people should look like. 80% of children have dieted at least ones in their lives. it seems -- >> very shocking, 80% of little girls, at that stage, also have a feeling about their body image, that they are fat and we are talking about 10 million girls in the united states have eating disorders, and only 1 million boys.

so, this is a problem that is gender-specific and i think occurs, first of all, because we put the wrong things into the ice box, wrong things in the refrigerator and you drink a lot of soda pop and drink candy and eat ice cream and gain weight and look at the tv and see someone who is perfect, look at a magazine and the celebrities look perfect and they are 18 years old and you are ten and i want to be like them, and then you drastically diet. to try to get there and i think the problem starts with us, with parents because we are not giving our kids the right choices to begin with. >> jamie: we can't control the media and what our kids see and, hear. >> you are so right. but we have to be conscious of this and we have to not promote dieting in our young people, but, try to get them to gradually... and the other key is exercise more. we are always talking yabout it on the show and get our kids out exercising, out with us for an hour or day maybe they'd have a more healthy attitude. >> jamie: at the same time, teenagers are getting gastric

bypass surgery. >> what do you think about that? i don't think it is healthy. >> jamie: i think every kid deserves a chance and ify are morbidly obese due to genetics or otherwise, they deserve it. >> the bigger question is, jamie, how did we get there? a third of the country, that are suffering from obesity, 17% of the teenagers are really obese. how did we get there and i think his point is well taken. if we are completely turning to robots, with the iphones and twitter and not spending enough time with our kids and, basically, just eating all of these sodas and sugar, next thing you know they are basically going for the diet, it is not healthy. so i think the take-home message is we don't need to necessarily blame media, we need to blame ourselves. you have to spend quality time -- as apparently, what does a nine-year-old or a ten-year-old know? what they see is the cover of the magazines and see beautiful hollywood and that is not reality. none of these models in my opinion are having healthy diets, they have a job and a profession and you don't and the

nine-year-old doesn't. and we have to feed them healthy stuff and we're guilty of it because of the jobs and spend quality time with your kids. >> jamie: family dinner which we talk about a lot. we have to move on to another topic. you made an important point. this is not exercise. right? >> good for the thumbs. >> thanks for reminding folks. >> eric: how much is too much, have you heard of the marine who is trying to actually attempt one million push-ups in one year. >> jamie: what a show off. >> eric: one million push-ups, that means he has to do. my math 2739 push-ups a day, and over 18 hours, he gets 6 hours of sleep, that means 152 push-ups an hour. >> if you can do it, why can't he do it? he has a resolution and he wants to really bring attention an awareness about the warriors in afghanistan and iraq and i

commend that. i think his main focus is to bring the ptsd to the surface. and a lot of the soldiers who come back, there is no transition period to go from all of that emotional stress, to a normal life. so, i commend him for that concept. but to do a million push-ups, sit-ups a day is not healthy. it will affect your joints and your heart and it will affect your joints. he has to -- as i'm, he has to do 2700 a day? i don't think it's a good idea. half-hour a day, three times a week is more than enough. >> having ridden with the wounded warriors i commend this because he calls them wounds without scars and he's talking about ptsd, post-traumatic stress disorder, traumatic brain injury and that is the biggest problem coming out of the wars and i commends him but extreme exercise has a huge downside and in fact several studies have shown that, studies in circulation and german studies in mice and humans have shown a

higher risk of arrhythmias, and, scarring to the heart if you do prolonged extreme exercise including marathon running, and so over time if you have done it many, many years, you have to watch out for that. >> eric: talk to your doctor about it. >> talk to your doctor about that, there is wear and tear and risk to the heart. your doctor should be in the loop if you are doing marathons. >> he is someone who should be watching tv and texting more! >> eric: we commend you both. >> jamie: and i commend you both for... >> the wounded warriors are doing great work. >> jamie: there are new concerns you may not get all the warnings you need when it comes to the medications you're on. some of them have side effects. the doctors want to remind you about. we'll be right back. those little things still get you. for you, life's about her. but your erectile dysfunction - that could be a question of blood flow. cialis tadalafil for ily use helps you be ready anytime the moment's right. you can be more confident in your ability to be ready. and the same cialis is the only daily

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♪ >> eric: back with "sunday house call" and the doctors, new questions are being raised whether or not drug companies are properly informing patients about the side effects of their medicine, recently several companies have been accused of just that. dr. siegel, you get a prescription. you go to the drug store and, it comes out with a gigantic ten foot long small-type page of side effects and things for reading it.

>> i'm not here to tell people to read those long lists, biblical lists, the issue here, eric is something called off-label use. gsk, glaxosmithkline has gotten into a lot of trouble and paid out $3 billion to the federal government for avandia and wellbutrin and paxil and, avandia they got into trouble because it led to heart problems and wellbutrin they promoted it for use for weight loss and the issue is, what are the drug companies saying they do and what do they actually do and studies show off-label uses where you prescribe something not for its actual indication, 21% of prescriptions but 73% of the time it doesn't work for them. i don't think it is a problem that dr. samadi and i have. because, frankly, i don't want to brag, but i look carefully at the drugs i prescribe and decide what their uses are and sometimes they are off-label but i look at the basic research on the drug and i don't rely on drug company information and you want your doctor to do that. your doctor should do independent reading and

independent research before they decide what they will do and shouldn't rely on drug companies. >> eric: so go to your doctor tomorrow and they prescribe something, what do you say. >> that is the question, no one is a better doctor for you, eric than yourself. you have to take care of yourself and because you get a prescription you have to ask them, what is this and what are the side effects? does it have interaction with other medications? it is a serious business, paxil is anti-depressant for adults and promote it for kids and wellbutrin is another anti-depressant and they use it for treatment of obesity, and erectile dysfunction and they have the other one, avandia, for diabetes, and, they never talked about the side effects which is the heart attack and congestive heart failure and is a serious issue. ask the question and you have to be your own advocate and i learned that very early on, in my training, always keep a record of everything that the doctors give you, and always ask the question, and if you are not happy get a second opinion and, it talks about the marketing of drugs, and some of the procedures out there, that you

have to very carefully read into it. >> eric: and if your doctor prescribes something, should you say i'll taking x, because another doctor could prescribe something else. >> that is important and your doctor is your quarterback and as david says you have to be your own advocate and your doctor is your quarterback and i want to end by saying it is not just gsk, it is other drug companies as well, major companies that had the problem. >> jamie: great information and we love when you give us the questions, we can ask as patients and here's the question i have. are you a morning person? or a nightowl? there is research that says which type you are could be linked to your level of happiness. we'll be right back. [ gans ] [ marge ] psst. constipated? phillipscaplets use magnesiu an ingredient that rks more naturally with your colon than stulant laxatives, phillipscaplets use magnesiu for effective relie of constation without cramps. thanks. good morning, students. today we're gonna continue...

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>> i love taking that afternoon nap. l are some studies that show the mri of morning people show a lot of activity around 9:00, but the night owls are usually around 9:00 p.m. what they are finding over here is most young adults are usually night owls, and they function better at night. as we get older, we are becoming more like a morning people.

there is some truth to it. i think it has something to do with the light and the fact you wake up earlier and see more light and go to bed earlier. i would say you are probably a morning person. >> i am not sure. so by noon everything in your day is done you would be happier i bet. >> that's the idea that society itself is surrounded around morning activities. so the college students are more night people. if we are going to come on this show and talk about great studies like the one injecting foresee sure, this study i am calling this hooey. i want to know what time they asked these questions. this is a questionnaire. your answer probably depends on what time you got the questionnaire. this isn't the same kind of science. it is fun, and it is fun to say maybe morning people are happier , but the reality is this isn't real science. >> we had fun with it, and we had fun with you too. such great information. thank you both. >> of course if you want more information on today's topics