if you're a man with low testosterone, you should know that axiron is here. the only underarm treatment for low t. that's right, the one you apply to the underarm. axiron is not for use in women or anyone younger than 18. axiron can transfer to others through direct contact. women, especially those who are or who may become pregnant, and children should avoid contact where axiron is applied as unexpected signs of puberty in children or changes in body hair or increased acnen women may occur.

report these signs and symptoms to your doctor if they occur. tell your doctor about all medical conditions and medications. do not use if you have prostate or breast cancer. serious side effects could include increased risk of prostate cancer; worsening prostate symptoms; decreased sperm count; ankle, feet, or body swelling; enlarged or painful breasts; problems breathing while sleeping; and blood clots in the legs. common side effects include skin redness or irritation where applied, increased red blood cell count, headache, diarrhea, vomiting, and increase in psa. see your doctor, and for a 30-day free trial, go to axiron.com.

"sunday house call" is here and joining us this morning, dr. marc siegel, associate professor of medicine, author of the inner pulse, the inner code of sickness and health. >> and dr. david samadi.

>> good morning,. >> great to see you. >> welcome to sunday. an amazing topic this m rning. a look at one of the most remarkable medical breaks through of this past year. we'll begin with a smart pill. this thing is science fiction. a sand-grain, penny microchip like you pop in your mouth as a pill and it records the times the drugs you take, when you take them. doctor siegel it sounds like star trek. a tiny pill that tracks what you do? >> the size of a grain of sand. i think it's a game-changer. the way it works is -- it's fda approved. basically it goes into your stomachs in a pill. and we'll be able to add to almost all medication. it's activated by storm system system -- stomach acid and a receiver will tell you did you take the medication, where in

your body is the medication you took? what's your heart rate? what's your respiratory rate? is it interacting with other medications? it allows me to see if a patient took the medication. people think i'm being punitive. i said i took it but i didn't. people that lie about it, i'm more concerned about people that forgot if they took it. that's a huge medical cost. people can't remember. i can't remember if i took my lipitor. a lot of patients can't remember. they put it in a special pill bottle. if i could track it and track the interactions and physiological responses it will help me. >> 9 9 cents, plastic thing with the days on it, now this fancy pill. when do you think it's going to be out? >> soon. but if you look at 2012, this was a fantastic year for medicine. not just from science standpoint but from technology. what this does is really once you take the pill and you have

this chip in your system, now you're going to treat the patient from inside out rather that be outside in. that's the importance of this. you can get that information. now we check the vital signs, it can come to your iphone from the microchip to the sensor and the patch. you can communicate with your doctors. >> question. you take the pill, and i won't get specific, but it doesn't stay forever. >> that's a good point. the acid in the stomach is going to activate this. it's going to basically start sending the signal, it's good for about a week. after that it is biodegradable. what is important is for a lot of disease such as diabetes, you want to control the sugar level. we can learn what food would surge your sugar and adjust it. you talk about coumadin and blood thinning medications. there's a narrow parameter. we can find out what we're doing

with the medication, how to 0 control it and not go with just what the patient does. transplant patients will get a shot at this because if you give too much medication, it causes toxicity. if you don't get enough, you can reject the organs. so this is a great technology. >> the next step is it's going to tell us how well a medication is working. you gave this blood pressure pill, here's the affect on the metabolism and how the body is responding. >> when do you think it will be out? >> it's ready for prime time now but to the point we're talking about, a couple years. >> similar to the colonoscopy. >> who makes this up? >> your secret agent. >> alisyn: this year there were a lot of things invented. researchers created an artificial stint that could revolutionallize the treatment of wounds t flows like liquid

and easily shifts into any shape. for what procedures would you use replacement of skin? burn patients? >> this is a study from cornell and it's very interesting because it's a hydrogel and the dna is the building block. it's a liquid form. say somebody has a sore, a nursing home patient with a bad sore. you can put this material on and it melts into the tissue and fills the gap. it has potential to change the whole plastic surgery injections, any filling on arms, legs, et cetera. what i like is also you can put in drugs such as chemotherapy and other medication. say you're doing a liver resection. you take part of the liver and inject this. plus chemo so you give localized chemo. another exciting technology. >> so you may not kill good cells.

>> exactly. >> in the past we use scaffolding, plastics, are proteins that didn't always take and we injected real cells. but the skin and body 0 often rejected it. now we're using dna and causing the dna to replicate and making this gel, called hydrogel, it's like a liquid. then when you add water, it's like instant oatmeal. >> a patient's own dna? or a item that -- >> it's synthetic dna and it's organic. it's not your own dna. but your body's not going to reject it. you could lather it into a wound, into a burn, and then you can actually add antibiotics so it treats the wound you're adding it to and in toronto, they've come up with centimeters of this stuff so you could use for large surfaces. >> not only is it the dna which makes it easy to heal, it's also

elastic. so it's not a tough tissue to work with, so great for surgeons and wound healing. >> it's part of what we found in 2012. >> the scientific version of terminator ii. this is what the -- >> all right, super heroes. stay in your chair. >> from fancy pills to this. something else was developed, progress in the fight against prostate cancer, increasing survivor rates to stopping it completely. new drugs have been approved. doctors samadi and siegel will fill us. in and spinal cord injuries, see what can happen? you may be finally able to walk again. we'll tell you more next. look, if you have copd like me,

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major medical break through for paralyzed patients. new technology makes a possible for people with spinal cord injuries to walk again. many like in man, manny, who is paralyzed from a car accident. >> this is a feeling of joy. i am back on my feet. you get to see people, talk to them at eye level. you're able to sit and talk, get up if you need to. it's a whole -- i don't know, it's like a bundle of joy. that's what it is, like a big bundle of joy and all the benefits come with it. >> that looks like a remarkable miracle for manny and others. we saw you there interviewing him. >> this is the second time in two months i traveled to mount sinai medical center to interview someone with a robot. >> i never saw you in a white coat. >> this is an amazing invention, xo, a skeletin survivessed

desurvivessed by the army. the bat relasts about an hour and a half but the weight is not on the patient, it's on the apparatus. he doesn't feel anything. they'll see how he walked before he was paralyzed. manny was paralyzed from the nip thes down from the car accident. with a hand operated console he can walk again and he feels so different. eric, this is so good for his overall health to be upright, psychologically, metabolically, physically, decreases his risk of disease and wounds. the head of the division there at mount sinai said we shouldn't look at growth factors and chemicals to get people to walk, look at technology, robotics.

we've had this technology. he thinks we'll be able to initiate it by sheer thoughts. i talked about it to dr. samadi, these things are related. if you see david operate with robotic arms you see the same idea. >> dr. samadi, it's unbelievable. it's so important for people who are paralyzed. >> mark is very kind. he's been in our operating room and technology of robotics has changed the way we view things. the surgery we used to do in open surgery involved a big incision, a lot of blood. we couldn't see. now robotic surgery revolutionized. you see people coming in for an hour surgery and go home the next day. exactly the point mark brought in, this is psychologically uplifting. for somebody to stand straight as opposed to looking up it changes your view of life. this is a time we should thank

and appreciate simple things in life. >> how many people other than manny can get this? >> mount sinai has been a huge supporter. they're investing tons of money in research, science and technology. it costs about 100 to 140,000, in 2013, it will come to people's home. >> can it go out of the lab, for example, in the hospital? can he get out on the street? >> yes. the computer, mark knows more about this, but the computer memorizes your movements. you move forward and it gives you the power to move. >> you use your arms to move. they're studying it there but it will go home, if you can afford it, in two years. >> a total inspirational miracle. manny, our hat's off to you and

all those who suffer from this. >> they did a good job. >> all the best, manny. >> medical, the developments are unbelievable. >> we hope more people can take advantage. that was a great development. we'll be back with the doctors. new developments in the treatment of advanced prostate cancer. men and the women who love them, stick around. [ male announcer ] when it comes to the financial obstacles military families face, we understan at usaa, we know military life is different. we've been there. that's why every bit of financial advice we offer is geared specifically to current and former military members and their families. [ laughs ] dad! dad! [ applause ] ♪ [ male announcer ] life brings obstacles. usaa brings advice. call or visit us online. we're ready to help.

2012 was filled with advancement including progress in street prostate cancer by improving survival and halting the progress. in the past two years, five drugs have been approved for treatment. dr. samadi your specialty and surgery plays a big role. >> these are advanced prostate cancer, cancer that already has spread outside the prostate, it's in the bone. it's a late stage prostate cancer but 2012, for prostate cancer, was a very busy year, psa controversy and urologists are upset saying it should go on. prevention is the way. if you find it early and cure the disease, we don't have to talk about advanced disease. for prostate cancer one of the

biggest things was pro advantage.áé?]ó?ñ we fight the prostate cancer. we had a lot of medications that reduced the testosterone and mark will talk about that. the message is that know your psa. if you're diagnosed and the cancer is contained in the prostated the cure rate is very high. find yourself a good surgeon who is an expert in the field that the not only cure your disease but also sexual function and continents so -- >> and target the therapy with the patient's cells is what you meant. but the minimally invasive procedure made a huge difference. >> the real really headline is

we focus too much on death rates. if you don't allow -- the cure rate is enormously high if you get it early. if you don't get it early we looking a the what we can do to keep you alive longer but you have a lot of side effects. prostate cancer is based on testosterone. once it spreads, the cancer feeds off testosterone. we use testosterone blockers. if they don't work, and we have 240,000 deaths a year worldwide. some of the other drugs, they work at blocking the receptors, the metabolism, it's all about getting testosterone from feeding the prostate. >> it's an important point. what you said is people should know that if you have surgery first and if the cancer comes back in small percentages, you can get radiation after surgery. once you have the radiation, it's very difficult to do

surgery after. >> good advice, thanks to both of you. >> coming up, a tool against the battle of obesity. a liner that helps people lose weight. we'll tell you how this thing works. [ sniffs ] i have a cold. [ sniffs ] i took dayquil but my nose is still runny. [ male announcer ] truth is, dayquil doesn't treat that. really? [ male announcer ] alka-seltzer plus fights your worst cold symptoms, plus it relieves your runny nose. [ breathes deeply ] awesome. [ male announcer ] yes, it is. that's the cold truth! can i still ship a gift in time r christmas? yeah, sure you can. great. where's your gift? uh... whew. [ male announcer ] break from the holiday stress. ship fedex express by december 22nd for christmas delivery. by december 22nd try running four.ning a restaurant is hard, fortunately we've got ink.

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