♪ ♪ >> this is "nightline." >> tonight, the so-called skinny shot sweeping the nation's. >> these are my genes from when i first started. my goodness, that's crazy. such a difference. >> what if my type 2 diabetes takes over? we go what of all i do isn't enough? >> approved to treat diabetes but part of a weight loss craze drastically changing lives but what of the downside? >> they are losing weight very quickly and they are losing volume breasts, their abdomen and what that leads to his loose skin. >> we'll be fda approved these drugs for weight loss? plus, lessons learned. deborah roberts paying tribute to the educator who changed her life forever.

>> i knew i was going to cry. it's been a long time. >> and sharing stories from famous friends like oprah and brooke shields about their own childhood teachers. >> it was all about seeing something you may not see in yourself. >> in the midst of a teacher's crisis, showing appreciation for the unsung heroes. and the met gala, fashions biggest night, the celebrity's, the over-the-top looks in the feline tributes. >> "nightline" will be right back. nlisted. try boost® high protein with 20 grams of protein for muscle health versus 16 grams in ensure® high protein. boost® high protein. now available in cinnabon® bakery-inspired flavor. learn more at boost.com/tv [tap tap] my secret to beating sniff checks? secret dry spray. just spray and stay fresh all day. my turn. secret actually fights odor. and it's aluminum free. hours later, still fresh. secret works.

>> thanks for joining us. we begin tonight with drugs like ozempic that were fda approved to treat people with diabetes but new data suggests this type of drug like mounjaro can also help patients lose weight and pharmaceutical companies are pushing for approval for weight loss. but the drugs are not without some controversy and side effects. here is his mona kosar abdi. >> so these are my genes from when i first started. that's crazy. such a difference. >> caitlin, a 30-year-old utah mom hasn't felt this good in decades. >> i'm super proud of all my progress so you guys tell me what you think, you can go ahead and write in the comments your opinion of it.

>> she is 1 of thousands of americans whose lives have been transformed after taking a new class of injectable drugs like mounjaro and ozempic buried >> i started it september 1st of '22 so i've been on it, i think it's been almost seven months now. i'm on my dirty sixth week of the shot and it's just been amazing. my doctor was like you are a whole different person. >> since starting mounjaro in september of 2022 -- >> i'm so proud of myself. >> her life is changed. >> i thought i would give you guys are up 360 view since it's been a while. because she has since lost over 80 pounds, documenting her journey on social media. >> another beautiful dress from them, do you think we like the first one or this one? >> mounjaro and ozempic work mimicking a hormone in the body that make you feel full. >> patients are so excited. >> last week eli lilly, the company that makes mounjaro release the results of all large-scale stage iii study it

says show you nearly 16% weight loss over a nearly 17 month period among people who have type 2 diabetes and obesity. >> how significant is that, can you put it into perspective? >> it's incredibly significant. in other medications weight loss was 3-8% maybe for patients but the percentage number is 15.7% on the highest dose in a phase three trial for diabetes has just not been shown before. >> the company released the data as part of its weight loss approval request to the fda, potentially opening the door for patients to have the drug covered by insurance. mounjaro is currently only approved to treat type 2 diabetes with a pharmaceutical company says the fda could decide whether to approve the active ingredient in mounjaro for weight loss as early as late 2023. >> hey, beautiful people. >> she got lucky when eli lilly offered a temporary coupon for mounjaro, currently paying only $125 per month, but it expires at the end of june.

whether she can get insurance to cover the drug may depend on whether the fda approves it for weight loss. >> i'm hoping that it will get approved so that for the next year i won't have to worry about it and my insurance will cover it, but it's very expensive out-of-pocket, it's around 900-$1400 a month and i don't know about you guys, but i don't -- it's a lot of money. and your health is worth it, but it's just -- it's the fact that these things that should prevent other health issues from happening should be affordable for people to have what they need. >> while ozempic and mounjaro can be really effective for folks who are obese, doctors generally don't recommend using them just to shed a few pounds. the long-term side effects aren't really clear yet. the ozempic ads mention a few risks. >> serious but dormant side effect may include tinker titus, gallbladder problems may occur. >> doctors see these medications as a potential game changer. >> what you think these drugs

are so in demand right now? >> they work. they work remarkably well and they work in a wide variety of patients. >> the drugs, so popular, there was a nationwide shortage frustrating some people with diabetes who couldn't get their medication. now they are largely back in stock. whether it is mounjaro. >> what of my type 2 diabetes takes over mack >> what if all i do isn't enough? >> ozempic. ♪ ♪ >> or a similar drug, it seems like the pounds are coming off everywhere you look. jimmy kimmel joked at this year's oscars. >> everybody look so great, when i look around this room i can't help but wonder is ozempic right for me? >> and andy cohen quizzed dolores catania on a recent "watch what happens like was go. >> juju: are you on ozempic? what housewife isn't on ozempic? >> not one >> half your cast.

>> i wasn't going to come to the reunion looking any bigger than anyone else. >> more than 40% of u.s. population is obese, putting tens of millions of americans at risk for heart disease, stroke, type 2 diabetes and certain types of cancers and even death. while hollywood may be raving about it, rapid weight loss for any reason can lead to saggy skin. doctor is a surgeon in beverly hills, used to doing nips and tucks him patients looking for the perfect bikini body. >> they start to lose a lot of weight rapidly, that can often show quickly in the face. so it is not something new, but a lot of people are associated not with ozempic. >> but these days he's getting new requests from his patients who are on mounjaro and ozempic asking him to fix what some call ozempic face. >> i can inject fat into the upper cheek area. the under eyes, the lips, but i can't inject fillers or fat sometimes into the lower cheek

area. sometimes they are going to need a face-lift where i can go in, lift the face, excise extra skin and then inject fat in the deeper layers, called the lift and fill face-lift. >> he's also seeing patients with so-called ozempic body buried >> it is a real phenomenon. patients are losing weight very quickly in their losing volume in their breasts, abdomen. what that leads to his loose skin and that's a hard thing to fix unless we surgically excise that loose skin, whether that's through a tummy tuck, whether that's through lift with an implant. >> kaitlin has had her share of loose skin but she says it's a small price to play. >> bear with me as i am just trying to share my journey on how i can be better. i will be posting updates as well in the next couple hours on my first day. >> hey, guys! so good to see you! a little try on with you guys.

>> earlier this year we met caitlin for the first time, she had been on mounjaro for five months and had already lost 50 pounds. >> let's see if i can roll this up to really give you guys the view. but look at this, you guys! isn't that crazy! i can fit my whole hand down there. wow. i wore these at the beginning of my journey, size 30, i'm now size 24. >> i'm going to do a quick live way in which you guys just to check my progress and see how i'm doing. >> at her heaviest she says she was originally 403 pounds. >> honestly probably one of the deepest, darkest parts of my life. just not feeling like you could be yourself and with the way you want to. that's not a life for anybody. >> her life, she says, had become unmanageable. >> i had moments where i would sit and cry because it's hard. it feels like a drug, you just

find yourself doing it and it's hard to stop. >> kaitlyn had been told by dr. that she was prediabic. by september of 2022 she was ready to make a big change. >> i was on tiktok and i found a creator that had said she was using this medication and it was helping her into eating and she was 30 days binge free and i would like wow, could that be for me. >> if you haven't seen me yet i am on day one of my mounjaro journey. and i think you are winning. him >> seven months later she says her life has been turned around by mounjaro. she's hoping she can keep losing weight, staying confident in her own skin. >> just recently we went to the park and i was like i think i can fit on both of those and i was like you want to go on the slide with mommy and he's like yeah, i do.endo the slide and my got in the c lngnd it just -- i

as -- dtry, bu ijust- wa jus myself. >> our thanks to mona. up next, many of us have that one teacher who changed our lives. coming up, lessons learned. deborah roberts with the educator change hers. ♪ ♪ h-i-v, i didn't know who i would be. but here i am... being me. keep being you... and ask your healthcare provider about the number one prescribed h-i-v treatment, biktarvy. biktarvy is a complete, one-pill, once-a-day treatment used for h-i-v in many people whether you're 18 or 80. with one small pill, biktarvy fights h-i-v to help you get to undetectable—and stay there whether you're just starting or replacing your current treatment. research shows that taking h-i-v treatment as prescribed and getting to and staying undetectable prevents transmitting h-i-v through sex. serious side effects can occur, including kidney problems and kidney failure. rare, life-threatening side effects

include a buildup of lactic acid and liver problems. do not take biktarvy if you take dofetilide or rifampin. tell your healthcare provider about all the medicines and supplements you take, if you are pregnant or breastfeeding, or if you have kidney or liver problems, including hepatitis. if you have hepatitis b do not stop taking biktarvy without talking to your healthcare provider. common side effects were diarrhea, nausea, and headache. no matter where life takes you, biktarvy can go with you. talk to your healthcare provider today. want a worry-free way to kill bugs? zevo traps use light, not odors or chemical insecticides, to attract and trap flying insects. they work continuously so you don't have to. zevo. people-friendly. bug-deadly. my most important kitchen tool? my brain. so i choose neuriva plus. unlike some others, neuriva plus is a multitasker supporting 6 key indicators of brain health. to help keep me sharp. neuriva: think bigger. [stomach growling] it's nothing... sounds like something. ♪when you have nausea, heartburn, indigestion♪

♪upset stomach, diarrhea♪ pepto bismol coats and soothes for fast relief when you need it most. when you find your reason to go on, let it pull you past the doubt. past the pain, and past your limits. no matter what, we go on. biofreeze

♪ ♪ >> do you remember your favorite teacher? you know, the one who shaped your life or your worldview? our own deborah roberts decided

to collect stories from her celebrity friends and colleagues to share how teachers taught them life lessons. of course she started with her own story. >> it's morning in. georgia, my hometown two hours south of atlanta and as the sun rises over my old school, you see it, the buses heading to perry high. and so on mine. >> this will be fun. >> to reconnect here with somebody who changed my life forever and the memories come reason back. >> i would spend a lot of time i hear of course talking to my friends at my locker and then head over to the library, which is a place that i just love. >> our former school librarian mrs. kathy tallon had an enormous lifelong impact on me. >> cafe just made everybody feel so welcome. >> and on this day years after she first encouraged young deborah to think big and ask questions about the world, i've gone back to thank her. kathy is in here.

>> have a seat. >> hello! hello! >> i'm going to cry! >> hello. it is so good to see you! >> oh, my gosh, it's good to see you! i knew i was going to cry. it's been a long time. >> a long time. but i've never forgotten her and her lessons on exploring life, always encouraging me to be curious. even teaching me yoga and meditation years before it became mainstream. >> look at that! i remember the bow pose. >> but most importantly... >> there you are. >> she didn't just ask questions of her students. she listened. >> teachers who pay attention to the students and are willing, bold enough to point something out whether to straighten them out or to encourage them, it's paying attention i think is critical. >> and that's what i think sometimes like that fire.

>> you encouraged me to think big and get out there and not to be afraid. >> yeah. it's good. >> thank you. >> you're welcome! >> that was so great to be able to thank her in person! >> she said to me you are organized and you are smart and ambitious and i said i was? i thought i was a mess in high school and she said no, i saw something. >> it is so clear she saw you. why do you think the stories are so emotional for everybody? >> summoning people even cry when they told me about the stories because they hadn't thought about in a long time. oprah talked about how she was seen and she was valued and it wasn't about lessons that they taught you and academics, it was about they saw something sometimes in a kid, sometimes for good and for bad and they would sort of pull you back or inspire and it was all about seeing you -- seeing something you may not see in yourself. >> there are a lot of boldfaced names in this book, bobby brown, trista turlington, george and robin and michael strahan and brooke shields even, but is there a consistent theme among

the stories that you heard? >> there is, and i think they g from the teacher, something that the teacher saw or imparted to them. it wasn't about a lessons. they can barely remember the math problems that they solved but that teacher who made them feel special and made them feel smart. >> and that is something that stays with you forever and sets you on a course. he also tried to hurry up this project because in the midst of this teacher crisis you felt like it was critical to get this out. >> absolutely. when i was talking to the publisher they were like maybe 2024 and i said no, i have worked for 2020 and "nightline" and "good morning america," i can do this, i will crash this. the story has to come out now because teachers need this now. they need to be reminded that they matter and that they are cherished and i think we are losing that right now. >> teachers are burned out, they've gone through the pandemic, there are so many crises right now and also the politics that they've become part of the crosshairs of all that. >> more dissatisfaction right now among teachers than in 50

years. fewer people wanting to aspire to the profession in 50 years so they need to be reminded that we see them and value what they do and we also need to help them. >> so how do we help them? you are giving proceeds to this book. >> i'm giving some of the proceeds, the donors choose and that's an organization that provides resources for public schools but we need to thank teachers, we need to say to them we appreciate what you do and i think we also need to have a voice and give them a voice and help them know that we want to see them be able to return to this idea of contributing and doing something and being autonomous. >> you set out in history we've been at this point before and we overcame. >> that's right, because we think about this is just this moment of crisis but in the '70s teachers were experiencing a lot of discontentment and we paid big attention, there was a government study and people -- teachers were paid better and it's not about the pay. we know teachers don't do it for the pay but when we focus on them and pay attention and show them we want to help solve the

problems because we want them to have a good experience, it mix a difference, we can do it again. >> okay, you've been so busy and you are heading to the coronation this weekend! what you looking forward to? >> my gosh, well, its history. we haven't had a coronation in 70 years, if you are under 70 you haven't even thought about this, so i think history but i'm also interested in hearing how people look at the monarchy today because it's a different world. a different world. >> so interesting and i can't wait to see what you are wearing. lessons learned and cherished, congratulations, it's a beautiful compilation. >> thank you. >> well done and it's going to be out tomorrow. musical physical >> coming up, the met gala. the celebrities showing up and showing off for fashions biggest night. oking up ♪ ♪ i've got symptom relief ♪ ♪ control of my crohn's means everything to me. ♪ ♪ ♪ control is everything to me. ♪ feel significant symptom relief with skyrizi,

including less abdominal pain and fewer bowel movements at 4 weeks. skyrizi is the first and only il-23 inhibitor for crohn's that can deliver both clinical remission and endoscopic improvement. the majority of people on skyrizi achieved long lasting remission at 1 year. serious allergic reactions and an increased risk of infections or a lower ability to fight them may occur. tell your doctor if you have an infection or symptoms, had a vaccine or plan to. liver problems may occur in crohn's disease. ask your gastroenterologist how you can take control of your crohn's with skyrizi. ♪ ♪ control is everything to me. ♪ learn how abbvie could help you save.

thousands of women with metastatic breast cancer are living in the moment and taking ibrance. ibrance with an aromatase inhibitor is for adults with hr+/her2- metastatic breast cancer as the first hormonal based therapy. ibrance plus letrozole significantly delayed

disease progression versus letrozole. ibrance may cause low white blood cell counts that may lead to serious infections. ibrance may cause severe inflammation of the lungs. both of these can lead to death. tell your doctor if you have new or worsening chest pain, cough, or trouble breathing. before taking ibrance, tell your doctor if you have fever, chills, or other signs of infection, liver or kidney problems, are or plan to become pregnant, or are breastfeeding. for more information about side effects, talk to your doctor. be in your moment. ask your doctor about ibrance, a pfizer product. illinois is in the middle. and what do you find in the middle? the meeting point of humanity and history. it's the middle of the architectural revolution. welcome to the middle of everything.

♪ ♪ >> finally, the stars were out tonight at the met gala, fashions big fund-raiser. this year's theme honored the late karl lagerfeld, who, during his six decade career designed haute couture for some of fashions biggest names like chloe, fendi, and chanel. some stars making bold fashion to honor the legend. rapper bad bunny embracing his aesthetic and a monochromatic white suit with a 26-foot long flower train. cardi b also donning a white wig and black floral dress. he famously had a feline. so many on tonight's catwalk paying tribute, including musician lil nas x in his glittery number. actor jared leto both before and after he took office monster cat

costume. and rapper doja cat. wnba star brittney griner recently freed after being detained in russia for nearly ten months walks the red carpet with her wife. priyanka chopra and nick jonas, jennifer lopez, pedro pascal, mary j. blige, kim kardashian, viola davis and newly minted oscar-winner michelle yeoh. tennis legend karina williams and model carly kloss making old-fashioned statements and revealing baby bumps. a very pregnant rihanna arrived nearly two hours late wearing a white valentino dress covered in chanel's iconic flower. her partner a$ap rocky were killed. but the biggest star of the night may have been a cockroach that appeared on the white carpet. >> get a photo! >> receiving a paparazzi treatment and sending twitter into overdrive. >> and that's "nightline," you can watch all of our full

episodes on hulu. we will see you right back here, same time tomorrow. thanks for staying up with us. good night, america.