thanks so much for watching. >> news updates are always on. captioning sponsored by cbs >> ninan: condemning a killing and demanding answers. there are calls for saudi arabia to immediately produce the remains of jamal khashoggi for an independent autopsy. u.s. allies and lawmakers are skeptical about the new explanation that the u.s.-based journalist was killed in a fistfight. also tonight, the migrant caravan crisis. mexican authorities allow dozens of women and children into the country, but thousands more midprants are still blocked at the border. we are there. a new type of treatments shows promise against aggressive breast cancer. deadly attacks in afghanistan as voters go to the polls in a

high-stakes national election. and who wants to be a billionaire? the largest jackpot in u.s. history ignites lottery lunacy. > > ninan: good evening. i'm reena ninan. amnesty international is calling on saudi arabia to immediately turn over the remains of jamal khashoggi to an independent autopsy. the human rights group says that the saudi government's new explanation, that the u.s.-based journalist diedar a fistfight in the saudi consulate in istanbul, is not credible. u.s. allies and lawmakers also have doubts. khashoggi was a contributor to the "washington post." the newspaper's publisher today called the saudi's changing story a cover-up and a "face-saving solution to an atrocity that appearses to have been directed by the highest levels of their government." more now from holly williams in istanbul. ♪ ♪ >> reporter: it was around 1:00 in the morning local time

when saudi arabia finally changed its story, admitting after nothing but angry denials that veteran journalist and "washington post" columnist, jamal khashoggi, had died inside the saudi consulate in istanbul, turkey. he walked in, apparently to get some official paperwork, on october 2, and was killed, according to the new saudi account, after getting into a fight and a quarrel. 18 saudi nationals have been arrested by their government and several officials have been fired, including the former deputy head of intelligence, ahmeahmed al-assiri, thought toe been close to saudi arabia's powerful crown prince, mohammed bin salman. but saudi arabia's new version of events has left many deeply unconvinced, including khashoggi's longtime friend, turan kislakci. was he the kind of man who would walk into the saudi arabian

consulate and get involved in a fight? >> jamal, i think he was not-- can't fight anything, you know? >> reporter: khashoggi's fiance, hatice cengiz, said today in a tweet, "may god have mercy on you, beloved jamal." khashoggi had become an outspoken critic of the crown prince. he'd been living in self-imposed exile in the u.s. since last year over fears for his safety. turkish officials have told journalists they believe khashoggi was tortured, murdered and dismembered inside the consulate, and many will suspect the prince is more culpable than the saudi government is admitting. mohammed bin salman, perhaps ironically, has now been put in charge of a committee to reform saudi arabia's intelligence agency. there's still no official word on what the saudis did with jamal khashoggi's body. reena. >> ninan: holly williams in istanbul. thank you, holly.

president trump in nevada today said he's considering sanctions against saudi arabia, but remains reluctant to cancel a u.s. arms deal with the saudis. here's errol barnett. >> i'm not satisfied until we find the answer but it was a big first step. it was a good first step. >> reporter: before bordering air force one in nevada today, president trump responded to saudi arabia's confirmation of jamal khashoggi's death, expressing hesitation to terminate a new $110 billion arms deal. >> i think it's over one million jobs. that's not helpful for to us cancel an order like that. that hurts us far more than it hurts them. >> reporter: the president says he would like to speak to crown prince mohammed bin salman, a man republican senator lindsey graham said was "toxic" and a "wcking ball." congress will be involved in crafting a response to the khashoggi killing, with senior republicans suggesting the expulsion of saudi diplomats, targeted sanctions, or cur tailing any future arms sales. >> the democrats want to throw open your borders to deadly

drugs andtehis the president has been out west holding rallies in summit of republican candidates fighting close midterm races. >> let's take back the senate, and we will change the world as we know it! >> reporter: also in nevada today is former vice president joe biden, supporting democratic candidates and fueling speculation of a potential 2020 presidential run. >> it's a conscious effort to divide the country. but we can't thereto work again. >> reporter: president trump also announced today he is withdrawing the u.s. from a nuclear treaty with russia, which dates back to the reagan administration and the soviet union. a national security spokesperson telling cbs news russia continues to produce prohibited cruise missiles. all this as the president's national security adviser, jnbo. reena. >> ninan: not that far off. errol, thank you. well, thousands of central american migrants who are trying to get into the u.s. are still

blocked at mexico's southern border pain number of women and children upon allowed through today, while others found their own way in. adriana diaz is there. >> reporter: this is the latest stop on a risky journey to a new future, or at least the hope of one. countless migrants, mostly from honduras, slept overnight on this bridge that stretches from guatemala to mexico. on friday, the massive group tore down a fence allowing some people to stream through. their reasons are clear, according to this honduran migrant. he said, "there's hunger, corruption, insecurity, and inuncertainty. that's forcing hondurans to leave our country because we can't live the anymore." mexico is process something women and children for entry, but today, others avoided the mostly deadlocked bridge by going under it. they used makeshift bos-ttlee td plywood. 17-year-old jayme aaron

hernandez is one of them. how old are you? 17? where do you want to go? to the united states. why? you want to start a new life and help your family move forward. the few people who have the proper paperwork, who have passports, who have visas, will be allowed into mexico, the others -- there he goes. he just jumped. and he's swimming... the water where he is, is pretty shallow, but there are parts of this river where the water reaches chest deep or deeper. it is dangerous to jump. but this is what a lot of people are resorting to in order to get to mexico any way they can. federal police were there to keep order but not stop illegal crossings. further south, in guatemala, police tried to create a blockade, but this truck tore through it, helping migrants join the caravan.

for the thousands still stuck on this bridge there are few options. some are waiting to try to be processed by mexican immigration. others are returning back to the guatemalan side, and some are still jumping from the bridge it try to swim to the mexican side. reena. >> ninan: incredible images. adriana diaz, thank you. well, scientists say a new treatment is showing promise in the fight against aggressive breast cancer. dr. jon lapook says that it could change the way patients are treated. >> reporter: three years ago, at age 39, maribel ramos was diagnosed with advanced breast cancer. the type was triple negative. >> feltang esad. i know that triple negative is a type of cancer that is really hard to treat. >> reporter: 10% to 20% of breast cancers are called triple negative because they don't have receptors, such as ones for estrogen, that can be targeted by certain medications. treatment options are limited, and these cancers tend to be

more aggressive with worse outcomes. in 2016, ramos entered a trial to test the immunotherapy drug tecentrix. the drug works by targeting proteins found on immune cells and some cancer cells. it's approved for bladder and one type of lung cancer. >> this is the heart and the bladder, but up here. >> reporter: dr. sylvia adams of n.y.u. langone is one of the trial investigators. she said the new drug helps the immune system recognize the cancer. >> there are killer cells already in the cancer, present and ready to fight, except that this cancer shields itself from the-- from the immune attack. so this drug is now able to take the shield down and basically paving the way for your own immune response to kilt tumor. >> reporter: the trial, at hundreds of site sites in 41 countries, followed 902 patients and found the combination of immunotherapy and chemotherapy improved overall survival by

nearly four months and nearly 10 months for those patients whose tumors tested positive for the targeted protein. >> hopefully, this will actually improve the treatments for many other women with breast cancer as well. >> the tumor was getting smaller, so every time, every four weeks, it was getting smaller and smaller. so i was getting so excited. >> this is the last scan from just last week that shows that she's still completely without any evidence of disease. >> reporter: three years ago, ramos worried she wouldn't see her oldest daughter graduate. last june, she did. this could change the way triple-negative breast cancer is treated, especially for women whose tumors are positive for the protein this drug targets. and, reena, because it was a controlled study, ramos did not know if she was getting the drug or placebo until just a few weeks ago. but with her scans improving so dramatically, she suspected she was getting the real thing.

>> ninan: dr. jon lapook. thank you very much, dr. lapook. afghanistan was rocked by a wave of deadly terror attacks today as voters went to the polls in a high-stakes national election. the parliamentary election had been delayed for more than three years. and this was only the third since the fall of the taliban in 2001. charlie d'agata is there. >> reporter: by the hundreds of thousands, they deified taliban death threats to take part in elections overshadowed by violence, ad confusion. more than 150 people were killed or wounded in attacks across the country. a suicide bombing at a polling station in kabul killed at least 15 people. between isis and the taliban, it's hard to tell here who's responsible for what. technical glitches and staff no-shows made matters worse. trained volunteers turned up late or didn't show up at all, perhaps heeding taliban threats to steer clear. afghans, tired of widespread voter fraud, demanded new

biometric machines. we visited the electoral commission to see how much time was needed to take fingerprints and photographs of every single voter. >> it will take around 50 seconds, up to one minute. >> reporter: one minute. >> yes. >> reporter: that seems optimistic. turns out that was optimistic the machines broke down, ran out of charge, or the people operating them just lacked sufficient training. "no one knows how to use this system," one woman complained. "it was easier when when we had to dip our fingers in ink." the hiccups means voting some some precincts will be carried over to tomorrow. and while a third of the country was unable to take part in elections because those areas were deemed too risky, early figures indicate that many of those who could vote did vote. so why does it matter to america? well, it's worth remembering therthere are still roughly 14,0 u.s. troops still serving here in america's longest war. even the semblance of democracy

is in everybody's interest. reena. >> ninan: charlie d'agata in afghanistan. coming up next, the largest jackpot in u.s. history ignites lottery lunacy.

>> ninan: more than $2 billion in lottery jackpots are now up for grabs. tonight's powerball jackpot is nearly half a billion dollars, and tuesday night's megamillions drawing will be the largest lottery prize in u.s. history. here's carter evans. >> there's a ticket. >> reporter: tonight, the lottery is in unchartered itory. the estimated $1.6 billion jackpot an all-time world record. >> next in line! >> reporter: lines formed across the country friday as people bought tickets for what was the second-largest lottery prize in u.s. history. >> $1 billion mega. one billion! >> reporter: and if it seems like lottery jackpots are getting larger and larger... >> let's see if i can makere.

big jackpots lead to big sales, and vice versa. so last year, lottery officials increased the price of megamillionses tickets. >> $2 each. >> $2 dollar? >> each. >> reporter: they also changed the rules, and the odds of winning decreased to 1 in 302 million. for some perspective-- you are about 80 times more likely to get killed by a shark. the current megamillions jackpot has been growing since july. >> the odds say somebody should have won by now. >> reporter: and for that eventual winner, cbs business analyst jill schlesinger says it's important to plan ahead. >> assemble a team of an attorney, an accountant, an investment adviser. you work towards your goals, your objectives, and you make sure that you don't go nuts, especially early on. >> reporter: the one problem with prize money this big is that it could lead to jackpot fatigue. take a look at the powerball for

tonight-- $470 million. it looks pretty paltry in comparison. the next megamillions drawing is on tuesday. reena. >> ninan: carter evans, thank you. up next, a spacecraft takes off a seven-year mission to mercury. of

>> ninan: the european and japanese space agencies launched an unmanned spacecraft into orbit today on a mission to mercury, the closest planet to the sun. about seven years from now, it will launch two satellites. it will investigate the planet's surface and magnetic field. during the day on mercury, it's about 800 degrees fahrenheit. at night, it cools down to minus 290 degrees. royal mania rolls on in

australia. prince harry and his american bride, meghan markle, attended the opening ceremony of the invictus games in sydney. harry launched the international paralympic event in 2014 to honor military members wounded in action. the duke and duchess of sussex are expecting their first baby next spring. still ahead, we'll go inside the new national law enforcement museum, where visitors are getting hands-on police experience.

>> ninan: the national law enforcement museum opened last week in washington. it has police artifacts going back to colonial times and high-tech exhibits that allow visitors to walk in the shoes of police officers. jeff pegues takes us inside. >> reporter: at the new national law enforcement museum, the history of policing in america immediately grabs your attention. there is the desk used by f.b.i.

director j. edgar hoover, and the helicopter that in 1982 was used to save five people after an air florida plane crashed in the potomac river. but it's law enforcements more recent history that has become a key focus. museum senior director rebecca looney: >> our mission, at its core, is to strengthen the bonds between law enforcement and the community. >> reporter: over the last five years, police departments across the country have confront accusations of officer misconduct and the shootings of unarmed black men. one exhibit highlights headlines from the 2014 shooting of michael brown in ferguson, missouri. >> to not talk about ferguson would be foolish because it's had a huge impact on how this country looks at law enforceme enforcement. >> reporter: but another puts visitors in the shoes of first responders. >> a driver has just run a red light. >> reporter: letting them act as an officer at a traffic stop involving an armed suspect.

sir, stay in the car. stay in the car! ( gunfire ) i probably-- >> you got him. >> reporter: the decision to allow visitors to simulate firing a weapon may be controversial, but instructor kevin bretz says it shows how police often have to make split-second, life-and-death decisions. and this is something that you allow kids to do here, too? >> if you're 12 and over, accompanied by a parent, we will bring you in, let them experience what it is to walk in the shoes of an officer and maybe start educating the community, and our police departments, too, to come together and start a dialogue. >> reporter: that dialogue may help policing in america by taking a look at its past. jeff pegues, cbs news, washington. >> ninan: when we return, they're not only college schoolmates. they represent three generations of the same family.

>> ninan: we end tonight in lowell, massachusetts , where three women from different generations of the same family,

are attending college together. chip reid has their story. >> reporter: if a couple of georgina hutchison's classmates feel like family, that's because they are. what do your friends say about the fact that your mother and grandmother are here on campus with you? >> they think it's pretty cool. i mean, it's not their parents, so... ( laughter ) >> reporter: all three are students at the university of massachusetts lowell. mary, who they call nan awasn'tably to go to college in her native ireland. after a battle with cancer, she decided to enroll. >> the love the kids, and it astounds me how they will hang out with me. >> reporter: they do? the kids hang out with you? >> all the time. >> reporter: deirdre fell behind in school as a teenager because of health issues and college became a distant dream. >>y saw mom go back to school and i was still terrified, and then finally it was like oh, my gosh, if she can do it, i can do it. >> reporter: georgina was the last to arrive. you transferred here?

>> yes. i missed my family, so-- >> reporter: you missed these two. >> i did, i missed them. >> reporter: grandmother and granddaughter, who have always been close have even taken a class together. and what was that like? >> as they say in america, it was very neat. >neat. >> reporter: very neat. so, georgina, you took a class with nana. >> yes. >> reporter: but you haven't taken a class with mom. >> and i will never. >.>> reporter: georgina is working towards a criminal justice degree. mary and deirdre are in it for another reason. 200are here because you love to learn. except math. >> give me chemo before math. >> reporter: chemo before math. >> yeah. >> reporter: who needs math when you can count on the love of family. chip reid, cbs news, lowell, massachusetts . >> ninan: what a great family. well, that's the cbs weekend news for this saturday. later on cbs, "48 hours." and for news any time, go to cbsn at cbsnews.com or download the cbs news app.

i'm reena ninan in new york. thank you for joining us the store has been drained dry.. after getting caught up -- in an underage alcohol sting. good evening, i'm brian hackney. i'm juliette goodrich. it's happened not once -- but twice in the past year.. at the store on nave drive in novato. good evening. >> this happened not once, but twice in the past year at the store on made drive. if it happens again, it will be the last. andrea? >> reporter: yeah, juliet. the novado police department said it actively works in the community to stop alcohol from getting in the hands of minors. in the last year, this safeway store has been caught selling alcohol to minors in at least two separate incidents. that means this store on nave drive can't sell

liquor for the next 60 days. all the beer, wine, and hard alcohol have been cleared off the shelves, replaced by items, such as water, jules, and chips. this is not the first offense for this particular store. abc says prior incidents of selling to minors occurred in 2014 and 2016 as well. according to the novapolice department, minor decoys walked in and showed their i.d.s, but still walked out with the alcohol. >> from what we can see, a lot of it looks like it may be a lack of training, as far as they're looking at the i.d.. the last two incidents i was present at, both clerks looked at the i.d., but maybe had trouble interpreting what it said to them. >> reporter: safeway released a statement on losing its liquor license. in compliance with an order from the department of alcohol beverage control, the store has suspended sales of alcoholic beverages, including a limited

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