rults came back. autumn franco has songbird fever. well, um... ...just get them some antibiotics. autumn franco has it. erika doesn't. doesn't make any sense. i'm sorry. there's an underlying condition. we also have a more pressing issue. they're dying. what could be more pressing than that? we already started autumn on antibiotics. this strain of songbird fever-- it's resistant. autumn developed septicemia. it's a matter of hours before she goes into septic shock. where are you going? where holmes went when he got stuck. to the scene of the crime. so you're just gonna... (sniffles) ...look at us?

erika: you're out of ideas, aren't you? i want to deliver my baby. today. please. before i get too weak. it's not over yet. there's something that i'm missing. (sniffles) we told you everything. you told me everything you know. your faces, your bodies-- everyone's faces and bodies are clues. tell us who we are, where we came from and what's gonna happen to us. you two don't look especially similar, but one look, and i bet you're related. you both have orbital hypertelorism-- your eyes are widely spaced. and that could be a coincidence, but then i see you both have two-three syndactyly, and suddenly, we got two traits in common. two-three what? syndactyly. webbed toes. the skin on your second and third toes never separated. i assume both of your mothers had it, since that's how you're related. actually, no. my mother doesn't have it. my father did. my mom didn't, either. neither of my parents did.

that's impossible. you can't have syndactyly if neither one of your parents had it. but i do. and they didn't. watson: neither one of autumn franco's parents could have possibly passed the mutation to two-three syndactyly, but yet she has it anyway. how? the only explanation is that she's wrong about who her parents are. watson: exactly. erika filipello's father had two-three syndactyly. he passed it down to erika and her brother damon, and there's no mystery there. does anyone notice anything unusual about paul filipello's eyes? they're widely spaced. he has a slight case of orbital hypertelorism. watson: notice anyone else with hypertelorism? ingrid: erika. her brother, of course. oh, my god. autumn has it, too. two-three syndactyly and orbital hypertelorism, two traits that flowed down from erika to her brother damon to autumn, all from one source. wait, you're saying erika's father is autumn's father, too? erika and autumn aren't just cousins.

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enroll by january 31st. covered california. this way to health insurance. enroll by january 31st. covered california. autumn's my sister?

half sister. three-quarter siblings. this is incredible news. if i'm right, you two share a mutation to the btd gene. it gives the body instructions for making the enzyme biotinidase. unchecked biotinidase explains all of your symptoms. (laughs softly) now, we still have to treat autumn's songbird fever. other than that, all you need is a ten-dollar biotin supplement, available at any drugstore. you'll be able to see again. you'll carry your baby to term. i-i'm gonna live? m-my baby's gonna live? yes. (grunting softly) autumn? autumn. (rapid beeping) patient is in septic shock. we need the ultrasound to find the abscess and surgery to cut it out. nurse: understood, dr. watson. where's the surgeon? where's the surgeon? the bridges are closed. the resident should be here soon. soon? soon she'll be dead. (thunder crashes)

mary: good afternoon, everyone. this patient has what looked like multiple abscesses on the ultrasound. they're around the liver, and we need to move quickly. cassie: dr. morstan? ("rainbow" by kacey musgraves playing) we got your favorite. good memory, cassie. i haven't operated in four years. ♪ ♪ ♪ when it rains, it pours ♪ ♪ but you didn't even notice ♪ ♪ it ain't raining anymore... ♪ mary: there she is. look how beautiful. did we tell you we picked out a name? autumn. after her aunt.

i have to get used to thinking of myself that way. get used to thinking of yourself as a godmother, too. seriously? you want to make this relationship more tangled? (laughs) ♪ you hold tight to your umbrella... ♪ just give it a sec. she'll move. ♪ trying to tell you ♪ ♪ that there's always been a rainbow... ♪ watson: got an update on autumn franco. the treatment has run its course. her songbird fever's gone. we're gonna be discharging her tomorrow. so, thank you for everything. night, dr. watson. ingrid. i hired you because of your résumé. no, that's the truth. it was one of the best cvs i've ever seen. and down at the bottom, in the... in the fine print, said that you played lady macbeth in college. there was no production of lady macbeth while you were at the university of chicago. you lied.

you have all of the qualifications in the world, yet you... you lied anyway. (laughs softly) so, you hired me because you think i'm a liar? i hired you because there's conflict inside of you. it sounds like you're diagnosing me. your every impulse, it pushes you to... put yourself first, but you try to be a decent person anyway. maybe i want to see which side wins in the end. or maybe moriarty gave me a clinical interest in... people like you. we'll set an appointment? you get one more shot. stop making me fight my way in. ♪ yeah, there's always been a rainbow ♪ ♪ hanging over ♪ ♪ your head ♪ ♪ mm ♪

♪ it'll all be all right. ♪ (song ends) sorry it took so long. what's in there, anyway? you could have told me. i'm not made of glass. somebody's been staying here. you own one car, the second parking space is free of clutter. coat hook on the inside is completely clear. a coat hook is never just empty. unless somebody cleaned it off in a hurry. is it anyone i know? you never met her. you are a better doctor now, john. whatever you did over there with holmes, it made you better.

i mean, you were always good. but you learned things with him. it's like... you can see into people's bodies and their souls. i'm lucky to be around you. but the old us... ...is never coming back. and what is the new us? you think i'm the reason you survived that fall, but there's something else. you have to find it. ♪ ♪

the game's afoot. we have a new case. who wants to amaze us with their insights? ♪ ♪ (bell rings) i could sit here all day. this view. the city looks so vulnerable. a fire might sweep down from the north. those rivers could rise. who knows? a germ may even write its name into history here.

how would you grant this place the mercy of nonexistence, shinwell? you know, i'm not really one for big ideas. professor moriarty, i presume. i was expecting someone... different. here you go. the samples you wanted. i'm watching. always and everywhere.

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