i have a feeling this is the beginning of a lively final 15 days. we will have continuing live analysis of tonight's debate on msnbc.com. and if you missed part of this debate, you can see it begin starting right now on msnbc. for now, i'm chuck todd in charleston, south carolina. from all of with us, we say good night. there was a time when you did everything you can and go home at night completely exhausted. physically, emotionally. >> you had to change everything. >> they're young parents, fighting an enemy within. a frightening condition that

of their children. it's possible each one may need a new heart just to survive. >> you get that feeling like it's never going to end. >> tonight, the latest in their battle. breakthroughs. setbacks. >> i just got to prepare myself >> all fueled by faith, love, humor, and amazing grace. >> i never felt, why us? >> what will it take to save a life? >> i just started thinking about transplants. >> you won't believe their story. >> you have a heart! >> you won't forget their courage. join them, where the heart is. welcome to "dateline," everyone. i'm lester holt. imagine five children in the same family, all with signs of a

we've been following their story for years now, and as you watch, put yourself in their parent's shoes. could you be as brave as they are? here's keith morrison. >> when jason bingham thinks of home, this is what he sees in his mind's eye. this as much a part of him as breathing. as his own heart. >> god's country here. we just love it. it's just a beautiful place. >> a good horse, faithful dog, a sturdy truck, about all he needed out here. until he met her. and what happened when jason met stacey was, well, love, brand new, unique.

god's country, it truly was. haines is a speck in a grand sweeping landscape. a town of 400 or so. near the oregon-idaho border. here, jason worked at his father's accounting business. stacey was a nurse at a nearby hospital. and this was the home they loved, and where they imagined they would raise their kids and live for the rest of their lives. >> hi, good morning. we're really late for church. >> it takes each one of them to make us a family. you have see ierrasierra, megan. lindsey. she makes sure everyone stays in line. and then hunter, who is just a happy, go lucky 5-year-old. >> oh, yeah. >> full of energy and life. and then gabe, who is the family clown.

coming home from work is just a party. >> but parties, of course, don't last forever. because the bingham family was about to become a terrifying medical mystery. one of the strangest, most off-the-charts unlikely stories we had ever heard of. it began here in may, 2006, when sierra, their eldest, threw up for several days. her parents took her to the doctor. >> the doctor comes in and says, we have one of three things here. it could be pneumonia, cancer, or something called cardiomyopathy. >> they gave her an echo cardiogram. the diagnosis was obvious -- heart failure. what happens when you hear a thing like that? >> first, you're in a misty fog, kind of like your world just came crashing in around you.

mind around it, grasp it. just fear. >> the doctors put sierra on heavy medication and sent her home. >> i remember asking her to plant some flowers that would be coming back every year, so if something did happen i would have some kind of memory of her, but she was too tired to do it. >> sierra was failing fast, nothing more the regional hospitals near home could do. so she was flown to children's hospital in the heart of the silicone family, a world away from oregon's eastern prairie. but even here, there were no easy answers, and the doctors gave jason and stacey the nose. without an almost immediate heart transplant, their daughter would die. >> it was horrible. when we say it was a nightmare, it was the worst time of our life. bar none, it was the worst three weeks of my life.

for a child can be months. it was time sierra didn't have. >> to say there's a time when you have shed every tear that you can shed and go home at night, completely exhausted, physically, emotionally, we had hit that point. >> we called as many people as we could and asked, please, pray for our little child tonight. 1:30 in the morning, we got a phone call. i thought, that's it. >> we thought it was for the worst, and the doctors called and they said, we have a heart for sierra. >> the bingham's prayers were answered. the next afternoon, sierra received her new heart. it had belonged to a 4-year-old boy. in the world of heart transplants, size matters more than age. her new heart would grow as she did.

everything was going to be fine. there was just never, ever any doubt. >> but they wondered why, why did sierra's own heart fail? did they need to worry about their other kids? the doctors assured them the likelihood was extremely remote. but just to be sure, they tested them both and the echo cardiograms detected no hint of the disease and there was no history of disease at all on either side of the family. >> so we thought, good, they ruled that out, it's not an issue. >> and then came lindsey's tummy ache. it was 2012, six years after see sierra sierra's transplant. lindsey vomited at school. >> we thought, we could not be -- i think both of us were in denial. >> they took lindsey to the e.r. in baker city where the doctor

jason and stacey about sierra. >> they said, she's got the same thing. >> she has an enlarged heart. >> i lost it. i couldn't keep my composure, and i remember just sobbing. >> lindsey grew so sick so quickly, that the very next day, she was flown to lucille packard children's hospital, the same place they had brought sierra six years earlier. now it was impossible not to think there was some genetic link involving their daughter's heart disease. so jason brought the rest of the children here, too, for tests. >> it was a friday, we were sat down and told of our five children, that all of them

symptoms that can turn into a cardiomy yop thi. >> now all the bingham children, every single one, would be confronted with the possibility of one day requiring a heart transplant just to stay alive. that's when we first met the bing ham binghams. and they agreed to trust us, to allow our cameras to follow them. through moments of despair. and courage. and bottomless love. a journey, unlike anything you've ever seen before. coming up, danger strikes the very youngest. 3-year-old gauge. >> they said, he's in complete heart block. we need to admit him. >> and little lindsey -- >> it goes from here and connects to my heart. >> is there hope and a heart for her?

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3 f2 sica) when trouble came to visit the bingham family of haines, oregon, it came in bulk, family size. all five of their children had cardiomyopathy, or markers for their disease. meaning it was in their dna, it could happen any time. at 12, sierra had been living with a transplanted life for half her life. on 2012, lindsay was put on the

to lighten the mood, jason promised to let his beard grow until he got a new heart. but limd ndsey was near death. >> it was like a heart transplant. >> the surgery was successful. however, while she was recovering in icu, her parents, whoed a been through so much, experienced another setback. it was gage this time. >> he wasn't acting right. >> they took him to the emergency room. >> they said, he's in complete heart block. we need to admit him. >> and we haddock fors checking him more than lindsay that night. >> can't imagine what that would do to you. >> unbelievable. >> and now gage was rushed into surgery to have a pacemaker implanted. by the end of that awful day,

post operative icu. but children are nothing, if not resilient. and within two weeks, gage was up and about, and lindsay, who had been near death, was proudly showing off her clever mechanical heart. >> it goes up into here and it goes connected to my heart. and this pumps in the air. and this machine helps me. >> so what else are we going to do now? >> wait until a heart comes. >> and naturally upbeat kid, but understandably one who is still quite afraid. what is that like to wear? >> when i stand up, you can find of feel it pumping. >> yeah. like you feel your heart beating, but it's beating on the

>> it's kind of scary. >> this has allowed her to feel healthy enough to be a regular 8-year-old girl. she wants to skip, jump, play. it's a false sense of security, because you forget she's still on a heart device that's keeping her heart pumping. >> the rest of the family moved into ronald mcdonald house across the street from the hospital. two bedrooms for all of them. and lindsay enrolled in city school. had ever known before. >> my class and grade was 28 kids. and so now my grade is 200 kids. >> but sierra has been where lindsay was now. and a day visit to the hospital offered advice to the endless needles and biopsies, from the daily terrors of her new life. >> i asked sierra what it was

>> what did she tell you? >> she said it was scary at first, but then you are fine. >> her siblings worked to build her up. and as jason and stacey waited, mired here in their impossibly bad luck, a remarkable lightness seemed to carry them through their long, draining days and sleepless nights. they did not complain. they remained upbeat for the kids and taught them the meaning of gratitude, for what they have been given. do they understand where hearts come from? >> yes, they do. >> donor and patient information is kept strictly confidential. but messages between the families can be exchanged anonymously through the donor network. so the binghams sent a thank you family to the donor family. they received a letter back from the grandmother of the

beat in sierra's chest. >> we are internally grateful to his mother and grandmother that wrote the letter. the sacrifice that she made to allow sierra to live. >> just as you'll be eternally grateful to some other family. >> right now i pray for that family out there, someone out there in the western united states has a child that's going to save her life. >> there was, of course, no way to know if or when there would be a heart of lindsay. jason and stacey were keenly aware that some 50 children die each year waiting for a heart. and here, as they waited, two months past. and then three. and the seasons changed. jason's beard grew longer. back in haines, oregon, people understood this cost money, lots

they had insurance, but it doesn't cover the medication the kids will need for the rest of their lives, tens of thousands a year. so the people of the town raised nearly $75,000. occasionally, jason went home to lend a hand on the family cattle drive or pick up clothes for the kids who were now yet growing them. >> i don't know how we're going to continue to live here. we want to live here so bad. >> but of course, they couldn't go home. >> today is labor day. >> they celebrated halloween in the hospital. followed by thanksgiving. then christmas. jason and stacey brought an artificial tree into lindsay's room. she put on the finishing touch. her beads of courage, each bead

procedures she's endured. the string wrapped around the tree three times. but christmas came and went. approached. they had been waiting nearly eight months now. >> what are you looking forward to? >> getting a new heart. >> yeah. and then? >> and go home. >> at 6:00 p.m. on february 12th, a doctor pulled stacey out of lindsay's room for a chat. something to tell her. she refused to tell the kids what she was told. >> she thinks she knows. >> i know. >> then stacey called jason and waited in lindsay's room for him to arrive. he past the nursing station, alive with excitement. >> guess what? >> i knew it! >> guess what?

>> what? >> look out the window. >> i have it. >> you have a heart! [ cheering ] >> it's going to happen. >> though she did, though what was coming next was, who could predict such a thing? >> we did it. coming up -- pump up the volume. lindsay's big sendoff to surgery. >> this is where i get the biggest hug in the world, okay? >> but wait, sierra? the medical roller coaster takes another dip. when "dateline" continues. i am the butler. these dogs shed like crazy. it's like being inside of a snow globe. it takes an awful lot of

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3 f2 (mu sica) i'm like, wake up, lindsay, wake up. but it's not. >> 8-year-old lindsay bingham has been waiting for a heart for 239 days. but now, finally, they have found a match. the doctors scheduled surgery

>> i'm just scared a little. i'm just scared. >> the swirl of conflicting emotions. even more so for lindsay's parents. they see it as news she had been dreading to share with jason. it's about their eldest daughter, sierra, who had a routine check up earlier in the day. >> sierra is downstairs. she's actually -- >> how is she? >> she's actually going to be admitted to the cisu. >> that's the cardiovascular intensive care unit. >> i don't know what the deal is. but what's going on? pressure really high, so they wanted to admit her. they don't know if it's

>> we have a daughter going in for a transplant in two hours and a daughter being admitted into the icu. i can't tell you how much i need that woman right there. >> jason and stacey try to put a positive spin on the news when they tell sierra. >> so they want to put you in a unit, and then decide if it's rejection or something else. lindsay is going in for a transplant and you're in the best place you can be right now. >> and they caught it. >> we're going to look back at this and just laugh our heads off. >> but the binghams know how serious rejection could be. if treatment doesn't work, sierra could go back on the transplant list.

honest. >> so heart being pulled in two directions on this day, jason returns to lindsay's room where he and one of lindsay's nurses try to keep her upbeat for surgery. lindsay learns she'll get her new heart in the first hours of valentine's day. and finally, 30 hours after they've learned about the donor heart, it's time to go. >> crank it all the way up. >> lindsay chooses her own soundtrack for her walk to the operating room. "somebody to love." >> i've got chills right now. seeing her perk up is everything i needed. put this thing around you like you need it. >> with her baby blanket transformed into a super hero cape, she's ready to face this event of her young life. jason works to keep lindsay's

>> this is where i get the biggest hug in the world, okay? i'll see you in just a few minutes, all right? >> okay, dad. >> you just go to sleep and you wake right up. >> and very soon i'll be better. >> yep. love you, lindsay lou. >> bye, lindsay. >> lindsay's room now needs to be made available for the next child in line. so jason and stacey pack everything up while they wait for the donor heart to arrive. >> they're going to be here in 15 minutes. >> hi, is this the heart? >> yes, it is. >> the chest is open right now. >> jason and stacey aren't prepared for the emotions they feel, as they see the donor heart arrive. >> the reality of it when we saw that cooler, a human heart in there.

hallway to my little princess who is opened up and ready and waiting for it. >> it's a strange emotion for observers, too, to watch life captured in this small container, passed from one child to another. even as a third heart struggles just down the hall. coming up, precision inside the operating room. and emotion outside. could two daughter's lives be on the line? >> you want to be happy for the one, but you feel so bad and

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>> lindsey lou bingham is in an operating room in pal alto, where surgeons are replacing her failing heart, where parents receive updates throughout the night and into the morning. but this doctor switches the conversation to sierra. >> i would like to regroup with the whole team and talk over things and see if we can come up with a more effective strategy. >> i guess i just need to hear you say there are options. >> there are options to look into. >> this conversation is taking place while lindsey is still in surgery, while doctors stitch together five separate connections, they begin with the new heart outside lindsey's body. then finish up once it's slipped inside. the heart has not beaten since it was taken from the donor nearly four hours early. the team will use a defibrillator to spark it back

immediately it begins to pump and find its rhythm. >> it took a couple hours longer than expected but everything went very, very smoothly. >> but the binghams now have two daughters in the cardiovascular icu. biopsy results show antibodies are attacking her heart. doctors say they'll try a treatment in which they attempt to remove the harmful antibodies from her blood. it sometimes works. sometimes doesn't. there's a chance that, to survive, sierra will one day need a second heart transplant. >> the reality of it is, it's never going to be the same. there's always going to be something. and now that always something is going to be times two, you know. it was really hard. you felt like your emotions are on a roller coaster and you want to be happy for the one, but you're feels so bad and you want

>> and, of course, there's little gage, who has the same heart disease and already a pacemaker at age 4. jason and stacey do their own form of triage, focusing on the sickest child. for now, that's lindsey. >> lindsey, we're all here now. megan is here. so is gage. >> but the days after a heart transplant are critical. but soon, she's up and walking without an artificial heart pump for the first time in eight months. and jason keeps a promise, by letting lindsey cut off the skagley beard he started growing the day she was put on the transplant. >> do it! yeah! >> two weeks after getting her new heart, lindsey is ready to leave the hospital. >> are you ready to go?

>> she's out of here. >> she isn't going far, mind you. just down the street to ronald mcdonald house, until lindsey and sierra are cleared for the trip they so desperately want. the one back home. but first, another biopsy to see if sierra's treatment stopped or at least slowed the rejection. cardiologist daniel burnstein will make the stall call. >> i think right now things are going call. go home and we'll see how things go the next couple of years. if things quiet down, no problems. >> words the binghams wondered if they would ever here again. and in spite of all they've been through, they're grateful. >> we've walked away twice now with two children still alive. and that's more than some parts can say that have to leave here. and we can go home with five

>> it was an almost surreal celebration that day in 2013. as if their troubles had been forced to retreat outside of their own little bubble of happy. there was the long drive home to haines, oregon. the big surprise welcome from just about the whole town. >> how are you? good to see you. >> sierra, overjoyed to see her own bed, and lindsey on the trampoline, just a regular kid again. are you letting yourself feel like you're home or can you quite go there? >> we've got a new norm now. to think that it's over, no. it's just the beginning. >> the family, though, was finally back on the ranch. and the binghams settled gracefully into their new normal. coming up, a setback for

>> i have to start thinking about transplant. >> you get that feeling like it's never going to end. >> and she meets her second family. >> tell us about nicholas. >> when "dateline" continues. lemme get a mcpick 2 introducing a hot new deal at mcdonald's that starts with you. lemme get a mcpick 2 now, get 2 delicious tastes for just $2 dollars so so good the mcpick 2 menu. mix and match new melty mozzarella sticks with a juicy mcdouble or golden fries with a classic mcchicken only $2 bucks for any two hurry in and choose your

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3 f2 (mu sica) the binghams have settled into their new normal, a life packed with the controlled chaos of raising five children, two of whom have transplanted hearts and a third with a pacemaker. two years have gone by. years during which they've managed to stay here in rural oregon, far from the hospital, in the home they love so much. lindsey is now off the

caused her face to swell. and has a fresh set of braces on her teeth. sierra is in high school, learning to drive. they make the trek to pal alto every few months for checkups and biopsies, which lindsey actually looks forward to. >> i like seeing the doctors. >> stacey is the girl's most loyal cheerleader. but on this trip to the hospital, january 2015, she's uneasy. >> i have a lot of anxiety over this one. is it going to be something simple or something we're not prepared for? that's the reality of it. >> sierra has had some swelling and a cough that won't go away. >> all those tubes filled up? that is a lot. >> one after the other, the girls go in for their biopsies. the procedure that once frightened lindsey has become old hat.

>> lindsey's transplanted heart is working beautifully. no sign of rejection. but what about sierra's? she's been fighting rejection for several years now. >> the real question, to be honest, to jump on you is whether or not it's time to start thinking about transplant number two. >> stacey's gut feeling was right. sierra's condition has worsened. dr. seth hollander explains they've run out of options to fight the on antsy bodies attacking her heart. times? you get that feeling of impending doom, like it's never going to end. >> transplanted hearts don't last forever. so if you're an older person who is getting a transplant, you may be able to live out the natural duration of your life before

out. but we didn't transplant sierra at 10 years old to get her to 10th grade. we want to give her a long, normal life. >> so sierra goes back on the transplant waiting list. but the doctors warned the wait could be as long as two years. and because of her condition, an artificial heart pump is not an option. as difficult as the news is to hear, in typical bingham form, stacey finds a bright side. >> we're grateful for the breaks we get, the home breaks. i guess it's go home and get that next breath of fresh air. >> a month later they're back at the hospital. they bring gage along for a pacemaker adjustment. at the age of 6, he's had a pacemaker for three years now. sierra was about gage's age when she had her first heart transplant. now that she's 15, she has a say

can even say no if she decides she doesn't want a second transplant. she's asked her parents not to keep any secrets about her about what's ahead, no matter how scary. and scary it certainly is. >> do i need to go in the middle of the night to keep track of a pulse? i get scared to death that she won't with there in the morning. >> in fact, sierra's condition deteriorates quickly and soon they're back in pal alto to kuwait for a donor heart. sierra attending prom at the hospital, with another patient. but then, out of the blue, the binghams receive an e-mail from the grandmother of sierra's first donor. a woman who saw our first report on the binghams back in 2013, and had a feeling that it was her grandson's heart that saved sierra.

binghams blog, she knew she was right. his name was nicholas. now she's learned that nicholas' heart, beating in sierra's chest, is failing. and she and her family, including nicholas' brother and sister, want to meet sierra. they meet in a park, not far from the hospital. >> this is sierra. >> hi, sierra. >> how are you? >> sierra brings a stethoscope so they can listen to nicholas' heart one last time. >> stacey told the family that sierra's first reaction was guilt that she couldn't keep nicholas' heart alive longer. >> it's just something that happens and we don't know why. but i do want you to know that

>> tell us about nicholas. >> the binghams assumed nicholas died in an accident. but now they learn the horrifying truth. nicholas was murdered by his drug addicted stepfather. his organs went to sierra and two other children. >> it's been easier on us knowing that he was able to help three people, not just sierra. so that has helped us a lot. >> they take pictures together, this unlikely blended family. and then, just three weeks later, just like that, the wait is over. a donor heart is available. much sooner than anyone expected. before she goes in for her second transplant, a reminder that in spite of her medical condition, sierra is a regular teenager, a surprise visit from

haven't we? >> minutes later, more goodbyes outside the o.r. doors they've been through before, and will be again. for jason and stacey, another long night of waiting and worrying. coming up, the operating room door revolves again. sierra out of surgery. and what's this? little gage heading in? >> to think he walked in here a happy little kid is pretty hard. life. so when my asthma symptoms kept coming back on my long-term control medicine, i talked to my doctor and found a missing piece in my asthma treatment. once-daily breo prevents asthma symptoms. breo is for adults with asthma not well controlled on a long-term asthma control medicine, like an inhaled corticosteroid. breo won't replace a rescue inhaler for sudden breathing problems. breo opens up airways to help improve breathing for a full 24 hours. breo contains a type of medicine

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she's 15 years old, and sierra bingham is about to undergo her second heart

the heart that kept her alive for almost nine years is failing more rapidly than anyone anticipated. the doctors are running out of options. >> i was getting nervous. i was really getting nervous, because it's heart wrenching to see your kid plummet. then how close to death's door are we going to be knocking before something becomes available. >> now the surgeons remove that failing heart and soon the donor arrives. doctors inspect the donor heart to make sure there are no surprises. it looks perfect. implantation begins. it's the middle of the night. jason and stacy have been waiting for news. >> it's a long night. so yeah, have a seat. everything went well, very smoothly. >> a healthy heart is beating in sierra's chest. she's been given a fresh start for a second time in her young

her recovery goes unbelievably smoothly. >> we're out of here. we're heading home, baby. >> sierra is released from the hospital in record time. after just eight days. she's already thinking about what she'll do with this next chapter. >> just the little simple things in life, like going to the beach, hanging out with friends, going to church and stuff. >> she and stacy plan to spend a brief stint at the ronald mcdonald house and surprise the rest of the family by returning home a week sooner than expected. but another shoe is dropped. a doctor asks to speak to them. >> your heart sinks a little bit, like why is it not to invite us to a barbecue? >> in checking gage's pacemaker, he's had two episode where is

beats. his heart failure is worsening, so in addition to the pacemaker he already has, he'll need to have a defibrillator implanted to shock his heart back into rhythm if it flutters again. but jason is worried. >> we'll see what happens. i'm here to go home in a little bit and not stay here for another year or two. as good as he's doing, i have to prepare myself that things could change. >> jason and stacy have had no time to recover from sierra's transplant. no time to recharge before this next crisis. they are emotionally exhausted. >> be brave. >> surgeons have warned jason

gage could come out of surgery on an artificial heart pump, similar to the one lindsey was on. it would mean he could not leave the hospital until a donor heart could be found. >> to think he walked in here a happy little kid and to think we could get the call any second now that they had to put him on a heart device, it's pretty hard. no artificial heart pump and finally, they get to go home. the hardware inside gage's tiny chest regulates the beat of his heart, but it can't stop the progression of his heart disease, which is happening much faster than anyone anticipated. he's always shaking his head no when his parents told him he would one day need a transplant.

just thrown up, gage known it was time. >> he goes, you're right, mom. he says, i need a heart. it's time. i think in his way he was accepting the reality of it. it was heart wrenching. >> just three months after his last surgery, gage is back at the hospital to have an artificial heart pump implanted in his tiny chest. he's asked if it's okay for doctors to remove a small piece of his heart to study what ease causing his and his sibling's heart disease. and then it's yet another goodbye outside the o.r. a place the binghams know all too well. >> you be brave, okay? you're a brave boy. >> gage's teddy bear, woody, goes in with him. surgery goes smoothly and soon gage is back on his feet. the equipment that's keeping him

lindsey's was. he can carry it on his back. and once again, all the binghams are back in pal alto, where they'll wait together for gage to get his new heart. in the meantime, he has a lot of questions. >> you'll feel so much better. you see how sierra and lindsey are? see how they are right now? that's how you'll feel. >> gage's will be the fourth transplant for this young family. their eighth open heart surgery. we have wondered so many times in the years we followed them how do they keep going? >> you have a heart! >> are they resentful? don't they feel sorry for themselves? but the binghams, not for a moment.