you know people in moscow say there are like whole web sites and facebook groups about the childfree lifestyle which i didn't believe until i saw the cover for the aug twelfth copy of time magazine yes child free is no real thing sadly basically these are people who have started a cool trend of not having children and using their time and resources completely for themselves you know if you don't want to have kids that is your business and i really couldn't change your mind even if i wanted to but there are people all over the internet who are just swimming in their own self-satisfaction like pigs in slop because they are part of the no kids trend the sickening part about this trend or

should i say it mentality is that these people glow in the door themselves for being too selfish to give their time and money to a child oh i'm the center of the universe and i'm proud of it. this is an extremely antisocial and destructive mentality to adore yourself for contributing nothing to anyone else nothing to society and nothing to the future but wait let me put it this way if your life is shopping wearing ironic t. shirts starbucks and texting on your i phone about your stupid feelings that maybe is for the greater good the church childfree but that's just my opinion.

oh and welcome to crossfire all things considered i'm peter all about the age of pill popping to what degree is big pharma hijacking captured the western medical establishment what is the real aim of the pharmaceutical industry to make people healthy or to generate healthy profits for themselves and is there anything we can do to break this unhealthy addiction. cross-talk big pharma i'm joined by david healy in bangor he is a professor of psychiatry at cardiff university and author of the book farmageddon we also have martha rosenberg in chicago she's an investigative health reporter in author of born with a junk food deficiency and in new york we cross to josh blum he's director of

chemical and pharmaceutical sciences at the american council on science and health all right cross talk rules in effect that means you can jump in anytime you want david if i go to you first is the western world over pharmac aided if i can use that term. yes it is using more and more drugs for conditions that we don't need to read treatments for but we need our drugs to work well for conditions we do need treatment for and the pharmaceutical industry is less and less able to produce the kind of treatments that we need at the moment on the. so if you and if you hoed shares and you probably see the companies you're doing quite well because they could make you must have profits selling treatments that on particular you needed to us recently josh how do you respond to that it sounds like it's for the pharmaceutical industry and not for health. mostly disagree. but is some of both but keep in mind that i don't represent the pharmaceutical company in

fact i was laid off by the pharmaceutical industry so i have no i have no dog in this fight i'm just speaking from my experiences as a researcher and my impressions following the the history of the last two decades or so and the major accomplishments that we've seen ok but then our major ok but josh is it really a profit driven business ites it isn't focused on health care everything it's a profit driven business and it is also focused on health care the two are not mutually exclusive the profit is necessary to do research for the next series of drugs and. there's no way around it no one else will pay to do it and no one else is capable of doing it ok martha do you want to weigh in on that. let's go to mark the first well thank you peter yeah i certainly agree with dr healy and i think that what we're seeing in the united states is

a lot of selling of diseases that didn't used to exist that now are selling pills through the t.v. ads and the direct to consumer advertising in the last fifteen years have really increased hypochondria and people who say well i can't sleep i'm depressed i have five cast reflux disease and all these things that we never thought before the t.v. ads selling the diseases to fell the pill. you know david when i was growing up no but nobody took the spills you know my generation me. more or less ok but so many children are medicated right now this i find that perfectly extraordinary. yes i agree and part of the issue here is that i think about the wrong to play in the. their own in that they're just doing what we would hope they would do which is to make profits what we've got is a bad system put in place which means to making profits out of the wrong things but

not producing pills for the things we need and they become largely marketing companies rather than pharmaceutical companies and part of the marketing is to get children on pills in a way that they can but on pills before and in particular it extends to the elderly the elderly are told at the risk factors for heart problems and stroke and diabetes and this something the other with the result that many people over the age of fifty five or six or more pills and treatment didn't choose death has become ability in its own right it's one of the leading causes of death and this wasn't the case fifty years ago john should be and that's a very interesting point to learn react to that i mean it's leading to death itself . that's nonsense. there are so i made a quick list of some of the breakthrough products the last ten or twenty years and these are real therapies that are really necessary and

a prevented lots of death and in no particular order certainly the aids cocktails come to the top of the list it's changed the entire world and the same thing is happening now with hepatitis c. where cures are starting to come out the two of which have two hundred fifty million people infected worldwide so don't be telling me that there isn't a medical need for that or that this is a some kind of profit making chemicals i should also mention some of the my personal favorite breakthroughs in the last ten or two. many years advair has put as much under control whereas it wasn't before. the drug called sophron which controls came third p. induced nausea and vomiting which is revolutionized chemotherapy entirely. there are drugs for migraine headaches.

osteoporosis and heart disease including local and i guess we should begin we shouldn't forget as well martha do you want to weigh in there because i mean people are taking more and more pills so ok and opiates well i would like to weigh and peter what josh just said because first of all as there is a very controversial as that's the physicians have asked to have that withdrawn because of very negative side effects that are not necessarily well publicized and that the cost when it's a bone drug are likely to be withdrawn because of the host of side effects that emerged after it was approved and after a lot of money with made on it i think it's really. just refer to the vaccines which big pharma has produced and ignore all that poor and a risky drugs that it's made billions and billions on by convincing people they are

at risk of us your prose or convincing people who are already taking to asthma drugs to take a third one ok it's just you want to reply to that before i go to do like you to suggest an alternative for advair for it's withdrawn i happen to have asthma and when i started on advair twenty years ago i threw my inhaler away and i haven't carried it since david are people taking too many drugs let me let me go to david now. we need all of you so that peter you know we don't just go back there's two three points what the list just gave you. one is that the aids drugs for instance didn't come out of the probably super company any of the breakthrough drugs we've come and come from university are and i funded research they have not come from sort of companies if we take the drugs that the companies are making money out of the entre depressants the stuff the mood stabilisers drugs like this there's an excess of deaths on these drugs in the clinical trials of just these drugs on their own compared to placebo and not true for very also while out there can be helpful

for people it leads to more deaths than you would otherwise expect the treatment of as a part of the problem here is that industry a terribly good at producing drugs for the drugs might be useful for people who are severely ill and efforts to just people who are severely oh that wouldn't be a big problem but in the marketing of these drugs to make money they extend the use of these drugs to people who have got very mild conditions where the chances that the person is going to benefit from the drug is almost zero and the chances that they're going to be home by the drug is fairly substantial josh you want to react to that and i get it but it's excessive get used to. first of all i'm in agreement with with pretty much everyone about the direct to consumer advertising i think it's awful. i think it shows the worst side of the drug industry rather than

the best and maybe they're making some money out of it but it's a pyrrhic victory and i think many of my fellow former researchers agree with this. with regard to your statement david statement about the where the drugs originate that is technically true but it's completely misleading because academia and government are good at developing screens and underlying biology that can be then used to screen for drugs. isn't to then spur the drug discovery process that is about one percent of the process. that's when things get difficult anybody can run a screen anybody can under under cover an underlying mechanism and no one can do anything with it because that's when the drug companies know what

they're doing and they can take a screen or a compound that was found by a screen which is completely useless and turn it into a drug over a process of fifteen years ten thousand compounds and hundreds of chemist people have no idea how difficult this is not my wife in the middle of it and it's almost impossible david. yeah you know i'd like to come back on two or three points here first of all i think josh is skirting the issues which is back in the one nine hundred sixty s. when industry would actually developing drugs in a completely different way we had much better life saving drugs than we have now and i thought put into the united states the best health care in the world in terms of life expectancy now the united states is full of the way down the list it's beneath cuba in terms of life expectancy on the other hand what's happening is the major problem companies now are running clinical trials in countries like russia

and it's not clear about the ethics of the trials that they run the recruiting patients russian patients to western trials where the patients don't always exist it seems and where the rest of this kind of get access to the data from these clinical trials to find out what has actually happened and it's because of this because companies can write goes right up to goes about trials where they hide the data and then market these drugs extremely heavily that the rest of us are being put on drugs that we don't need and ending up dead as a result all right i'm going to jump in here folks we're going to to go. short break and after that shall break we'll continue our discussion on big pharma stay with our take. oh no no no no no no.

i would rather ask questions for people in positions of power instead of speak on their behalf and that's why you can find my show larry king now right here on our t.v. question more. of . the fish he refused economic ups and downs in the final call long stay

the longer the deal sang i and the rest of the life until you meet casey will be every week on all coming. up with. me he. pleases. welcome to cross talk we're all things are considered i'm peter lavelle to remind

you we're discussing big fun. david who runs the medical establishment in the west as a doctor's physicians professors pharmaceuticals driver. well i think back in that one hundred sixty s. medicine had control over from. industry in a way that it doesn't have and back then the folks who come to a relatively small since then they've become global multinational corporations the most profitable corporations on earth and medicine has shrunk the capacity of doctors to control the pharmaceutical industry he's not what it once was so industry these days because actually one of the curious things here is that drugs are available on prescription only and this means that unlike what most people think when they take

a pill but they're the consumers of the pill they aren't your doctor is the consumer of the pill industry in essence target marketing on a very small number of people and they you that they deploy at least twenty to thirty thousand dollars per doctor per year understanding doctors better than they understand themselves six i know this is what leads doctors. to people who are so liberal at handing out pills compared with the situation during the ninety's sixty's he's if they only taught if they only treated teachers. way josh how do you react to that. i have a little trouble hearing just first address david's previous argument which is a fallacy and it's also a disingenuous argument and that's about life span in the united states. it's an easy argument to make and you can use it is an indictment of our health care system

and the pharmaceutical industry but in fact multiple papers that if you factor in violence automobile accidents suicides and you normalize it across the industrialized company countries the united states has the highest life expectancy it's not seventy that's number well josh what is the correlation between taking antidepressants and suicide for example and murder antidepressants definitely have their place in medicine they're not perfect they're far from perfect i think on the whole they've probably helped more people by far than they've hurt and they've probably hurt some people also but. you know that that is medicine and those are drugs there are various and there are benefits and there are not always clear answers for which is which ok we're talking about lives monster would you like to jump in well i would like to jump in on the end of the press and the world leader

how many negative parts of and i depressant is probably dr healy but what i would like to add because my background is advertising and marketing and i'm a reporter and i'm i'm thinking over the last decade or more that and i depressants are given for things that used to be treated transcendently in other words they used to say well you have anxiety take this when you go to the dentist you get on the plane and now it's like you have major anxiety disorder you need to be on this drug all the time because if it does. tripled their profit and the overall business model. mentioned give a start the kids the wife lifetime drugs is where the profits come in so this is why in the united states we have no we have a real lack of operative antibiotics because people will take them for ten days so there's no profit for big pharma to create life saving antibiotics whereas push

things are needed to out. people who don't need them ok let's go to david first of all go to josh but i use i depressants and i use most of the pills that we have but i can serve as a doctor is the quality of the pill is improving it is not improving compared with the pills available to me to the nine hundred fifty s. we have weaker and less effective pills now but specifically on the antidepressants it's just six to eight trials it's an excess deaths depressants and there are in the placebo arm of these trials so josh simply from the evidence to say that these pills have helped more people than not but evidence points the other way around just would you like to react to that if you could find it to a sixty if you can find it to a six to eight week trial that may or may not be true but it's largely irrelevant. these things don't work for six to eight weeks so i think you need to take

a look at five years out and and see there i don't know the answer i suspect you'd get a slightly different result josh josh we've had a look at this issue that's five years out if you look at patients who got sick it's a premium taking anti-psychotic drugs five years out of most of the patients who got schizophrenia these days who are on the drugs to commit suicide i mean the most of the loss of life comes from people committing suicide one hundred years ago patients. schizophrenia didn't commit suicide but we've got five years. didn't create the risk of death from suicide that's linked to the anti psychotics these patients are on but we didn't talk before. josh would you like to reply to that david i can't really expert on this i can't argue with you i don't know the

data ok mark i do agree with those of you. that are in your face every night. really you know they're in poor taste and i wish they would just go away but i certainly agree with both of you on that one thing you want to jump in and go ahead. yes i would like to jump in you know dr king was talking about the suicidal side effects of the and i depressants. are exhibit a in the united states are afghanistan and iraq. troops the suicide rate in the military is often actually one person a day and a large percentage of the suicides did not see combat and some did not even deploy the variable the only difference between this population and others of that age is that these are very doped up psychiatric cocktails. anchored by the s.s.r.i.

antidepressants which are suicide linked especially for that age group and to me it's astounding that the government allows big pharma to make it a cash cow and sell many of the soldiers are drug cocktails with four and five and six drugs and so many of that killing themselves and that's why and i think that the data shows as well as you would watch you know david i want to go back to something you said earlier because you made it so my doctors are pill dispensers now that's about it. yes it's. peter part of the problem here is that doctors haven't realized prescription only arrangements for drugs do it means that compared to a pilot for instance if you take a flight from moscow to new york the pilot has a real incentive to make sure that you get there alive because if you don't get there alive she will get there alive doctors on the other hand when they put you on

pills and we both think i mean we all think that doctors are just as much in the business of keeping us safe as pilots but in fact when a doctor puts you on a pill if you don't get to where she wants you to go she does get there and she can put the fact that you didn't get there down to the fact that you had an illness to no cost to the doctor here and partly because of the pills have become an answer to the stress that you're turning up the doctor poses the doctor if she gives you a pill it means you go away and it's meant that doctors have transformed from people who are cautious about using pills people who regarded pills as poisons which could do good if used with judgment into people who regard pills as fertilizers to be sprinkled as widely as possible see. would you like to respond to that. because when you go to a doctor you actually go into the army to to find it interesting go ahead. i find it interesting that everyone is focusing on pharmaceuticals and a.d.h. d.

drugs for instance i mean that's an easy area to criticize because it's murky. and. you know it is what it is and i cannot address the marketing of pharmaceuticals. you know as an expert because i was in discovery research but let me just turn it around a little bit and get away from this one area where there is seems to be. such an emotional component and i want to talk about the probably the two greatest contributions of the drug industry. in the last fifty years and that would be aids and hepatitis c. someone said before that hiv therapies started with the government that's partly true because a.z.t.

which was the first aids drug and didn't work wise and i h screening library it was there because it was put in by glass burroughs wellcome which is now part of glaxo. nothing worked on aids until one thousand nine hundred four when roche after many many years of incredibly sophisticated drug design put injuries on the market and that became the basis of the h.r.t. cocktails and you saw the death where the death rates drop. in oregon which i would want to finish with david how would you like to see this scenario change with the pharmaceutical sorry you got thirty seconds ok i think what we've got to do is that we have to change the system another involves changing the toxin status of drugs we may need to look at whether drugs should be available on prescription only but we certainly should insist that the public school companies kind of do clinical trials

and hide the data from those trials for the rest of us these data need to be to be openly accessible to experts who can scrutinize the claims that are being made about whether these pills or how full on off many thanks might get say this is a fascinating discussion and many thanks to my guest today in bangor chicago and in new york and thanks to our viewers for watching us here are so you next time remember. at least one. isn't. well told you my language well but i will only react to situations i haven't read the reports so i'm likely to put the no i will leave them to the state department

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the in the. in egypt the government crackdown on pro-democracy protesters shows no sign of slowing with the death toll closing in on one thousand and twelve clashes continue the egyptian court may soon free approach of former president hosni mubarak more on the new developments up ahead. and we may soon have a sentence handed down for bradley manning the army whistleblower faces a potential ninety years in prison for leaking government data to wiki leaks both the prosecution and the defense made their final arguments today more from fort meade coming up. and while the airwaves are filled with images of chaos in somalia there's actually more to it the nation has considerable resources that could provide.