you do a lot of this very early on to get speed minutes into this and this bit is not so easy for the likes of dominic cummings or for many others well long strokes are going to be going to be needed after the 31st of january and what do you see as the significance of this date of the 31st of january because people can say that is the date from which britain will be subject to all customs union and single market regulations from brussels and. and we will have no power whatsoever. as regards the regulations we now must know violet well a deal as you know for trade is going to be discussed i'm always amused by hearing politicians saying that they can do things within this timeframe all that time frame if the result will it will be done within the timeframe of 1011 months i don't think businesses will forgive politicians if they don't get home with this. because it's stifling employment and stifling the country's stifling. activity and

i'm not just talk about the u.k. i'm talking about many of the european countries that will stifle german is. trade activity which is huge the united kingdom and it's a no brainer i mean we export hall for what we import to be given and i want to know that statistic sorry to interrupt you. you're in trouble go ahead but if you just take that statistic you would have kind of thought let's get this thing done because it's actually in our interest to have a very harmonious exit exam because we're going to hopelessly wrong when he said that dr johnson had hitched his issues riders have to donald trump over the trade deal and that is why britain must support the united states on iran given johnson is actually double down on his support for the nuclear a g c p o e agreement i think koeppen labor of got it wrong quite

a lot from boris johnson they don't really understand and they've tried to portray him as another trumpy isn't he's actually a centrist by heart and i think. you know he's he's much more moderate than people think and that will probably be the tone of his coming to some extent but what you just said about european multinationals c.e.o.'s perhaps and boards believing that we've got to get this done now because as you said e.u. british trade is such a huge component of their businesses and world trade. then they have the pennies drop with them they're going to still fight it because european bureaucrats i think president taylor saying what this is a very good point very very good point pen it penny suddenly dropped the trade a business level but the european. government brussels has been open all the way through. and it will be interesting to

see how much pressure they're bored by the leaders of the countries like macro merkel to quickly speed up what should be a very sensible trade if not know who knows what's going to happen and it could be no deal which would be pretty disastrous for both parties but even more disastrous for europe but that if they still threatening yes but those who really want you to look at they are not if you look at the german economy which is not growing it's going backwards it has been very reliant on motor industry never once from says oh you can't use german boat manufacturers but what is being demonstrated in the next in the last 6 months to 12 months the slowdown an almost recession the german economy has been entirely due to the motor industry failing to summon up because if you see if you look at that alone how important the u.k. is to that motor industry then there will be significant pressures and they'll be

significant pressures from the child's need to make sure that she has strong trading relationships having been in business all my life the fact is the best type of people you can do business with are people who pay their bills on time. where the contract is supported by rule of law i'm where you have a free market economy now britain takes all those boxes so we are a market that is incredibly desirable for all these countries but you say that the european commission is trying to sue the u.k. at the moment for billions of pounds for alleged fraud between 2030 to 2016 i don't know whether these legal cases you see is another delaying tactic and if as you say angela merkel is pulling the strings then why would a slow wonderland be saying the deadline as it stands makes will break that impulse . well of all breaks a deal impossible already these procrastination. is going on there and on their own

head be it in my view ok better pull their finger out and get on with it well as you know they can threaten britain by a whole variety of ways what about the 3rd country deals with the european. through 3rd party deals all existing with the european union and the renewal of those in the rule over of those for britain apparently japan is saying japanese companies will rule it we locate of course motor companies if there isn't no deal breaks it but that country treaties with the e.u. will not be permanently rolled over with a break so i find these things rather a paradox. in that japan supposedly makes these noises about. you know withdrawing the car industry and i'm not surprised they've shot a plant in swindon because the cars are not really a desirable car in the way they used to be in the old days but then they go home or

they then go and invest oh by a property and things like that but i don't see any signs of japan not being interested in doing a deal with u.k. that will be a job for the trade own voice because honda would probably disagree with you there but that is that of course like we're. telling you well just as it is to live on to live she says the the price of a new deal breaks it is a distant partnership with the e.u. as a clean break bricks a killing machine fluffing that is more of this why boris johnson is such captivating. prime minister and leader is because he's positive. come out and say we come to this and can't do that he comes out say let's get this done let's get that done and by and large he has done everyone said no you can't redo the deal with trees a may go up he went did it there was a border in the eye. oh but it was very conscious of the role if some bots the ruler symbiotes but it's a far better deal than the trees made and the deal that was acceptable to the

members of parliament and he had less of a majority in theory than she did a good politician is someone who says let's do this let's try and do this let's let's see what's possible i've always said that why boris johnson would be leader of this country's gives hope you expect trade always now to be going around the commonwealth which you have a specific interest in and all these countries to rapidly study creating new frameworks of the british businesses can work with businesses in the developing world and the point about trade and i'm sorry fun of telling my grandmother how to suck eggs but what about trade is that is activity. with trade you don't necessarily have to have a trade deal we've never had a trade deal with the united states our biggest single trading partner and our biggest relationship we've never had a trade deal with them you really need a trade deal where the north think rules of engagement between parties are not certain will there aren't similar rules of law about. where the relation can

ship can take you and you need happens in developing country which happens definitely developing countries and you need to have a very clear picture of what i see needs to happen in a new global britain is for us to embed all selves in markets where there is big population growth we talked about nigeria which could have a bigger population than the united states by 2030 we look at indonesia which is already north of 200000000 a vietnam a very. fast growing population nearly 100000000 will be 120000000 i think 520252038 philippines a similar burgeoning economy and that's where we have to learn all over again. where we have to start selling product now if in order to support that activity we need a trade deal to give a certainty and in the relationship then of course we need to have that they won't

be done overnight because they're not sort of necessarily off the shelf things you know what is a mad chicken in one place is not the same chicken in another you know we have things we don't want to take they have things that they don't take from us but they're not as straightforward as the last but there are the there is there is a base of a framework and we countries like russia i mean there was a countries of britain sanctions and you britain sanctions china as well you know trade that there will be trade agreements frameworks i can't see that as being top of the list. i don't know. but you know i think. clearly relationships. for the future but i'm talking more britain getting you know. the global population.

the. potential. thank you thank you for the great british visit reza paul davis exposes the symbiosis of cancer in everyday life and how modern approaches a killing progress in cancer treatment told us a ball going above 2 going on the ground.

join me everything on the alex simon chill and i'll be speaking to us from the world of politics sports business i'm show business i'll see you then. basically ponder the future and look into 2021 fascinating stories our way you know i'm often said on this show that you can't have capitalism without capital corsicana capital without positive interest rates encouraging people to say and this next. dori this next whole show this next entire segment is going to be dedicated to this very notion. good food descriptions sound up to tell using even for the owners so how to choose just pet food industry is telling us what to feed our pets really more based on

what they want to sell us and was necessarily good for the pet. food may not be as healthy as people believe we have animals that have you know diabetes in arthritis they have auto immune disorders if allergies we are actually creating these problems and it's a huge epidemic of problems all of them i believe can be linked to fairy simple problem of diet and some dog owners so heartbreaking stories about their pets streets the larger corporations are not very interested in proving or disproving the value of their food because they're already making it a $1000000000.00 on it and there's no reason to do that research. on my one isn't ready along. side them. the way they were as of a time about what it was it was

a bit than that we listened as a bomb was more about. when the more than the side of. saying that i'm going to fit in but i'm before. them by the. devout right now i'm by the imam obama. gaming. welcome back rio may have been. on with threats to life on earth coming from war catalyzed by u.s. assassinations and climate change destruction scene of course australia but some scientists are asking not so much about the end of life on earth or even the origins of life on earth but what is life itself joining me is award winning professor paul davies whose new book the demon in the machine the hidden webs of information and solving the mystery of life is out for welcome to going underground

who are the demons of james clark maxwell well maxwell was a giant of theoretical physics lived in the 19th century where it's not very far from where we're sitting now at king's college in london unified electricity and magnetism and contributed enormously to the theory of heat and he came up with a weird idea in a letter to a friend it was just an idle thought that if there was some sort of tiny little being who could see individual molecules as they rushed around colliding with each other and could have some sort of shutter mechanism to manipulate where they went then without expending energy could accumulate all of the fast moving bollock your was over here all the slow moving molecules over there so this will get hotter than that and any competent engineer can tell you if you've got a temperature difference you can run an engine off it a heat engine and do work so max will seem to come up with a sort of perpetual motion machines something where just by using the information

of the molecular motions you could produce a source of work a type of fuel information as a type of fuel very radical idea simply paradoxical of the time well what's amazing about this book of course is the new use that to talk about the definition of life why do you think it is that we don't have a definition of life people do presume what it is you say in the book when a mouse is dead you know it's 90 percent alive nobody can really say what life is or how it began and there are plenty of books about what life does but this is a book about what life is about living matter how does living matter differ from non-living matter current scholarship. is and you explore that is it's about information yes so the key to understanding the difference between living and non-living and to unify these 2 great heroes of science physics on the one hand of biology on the other is this concept called information but it's also an abstract

concept and it's the branch of science called information theory that's about 60 or 70 years old. that treats information a little bit like the concept of energy we use energy in everyday life we talk about it in sort of colloquial terms but we also know it has a technical definition as an abstract quantity that can be passed from one system to another and it's always conserved something with information and we know that life is invested in information because d.n.a. for example is like the rulebook of life it's an instruction manual to build an organism but that's only just the start if we think about gene as set of instructions for something to happen building a protein for example genes coupled together to form complex networks that switch each other on and off information swirls around these networks information is transferred between cells cell signal each other and then there's that great

information process between areas that's probably the best example people can think of as biology vested in information and information processing so it's a very bad biology but it's not there in physics when you think about you know what is an atom doing processing information well you know it's that some sort of sitting there in a collection of atoms. don't have anything like a purpose or goal and yet living organisms do so somehow information is the glue that is going to unite the world of physics and the world of biology is as huge relevance for the treatment of cancer before i would. well let's go about it you retell it here story by yuri love's a big which is kind of relevant to this i think we use a kettlebell just fix a radio you might have to explain that which is why it's taken so long for us to get to where we are today that's a wonderful essay and the essence of this is that as we now understand it

when you think of a of a cell it's really a collection of modules and functional components if we think less about the individual molecules more about the signals and the information flow inside the system. and that's exactly the sort of approach you would take with the radio now let me give an example the particular essay referred to a transistor radio and say you had all these components together and if you went wrong for example you had a distorted sound well how do you fix it and you wouldn't go about fixing it by examining the atomic structure inside a transistor on something you would know that there are certain rules of radio rules with electronics and you could fix it a competent. radio technician would be able to identify 40 component and rewire it

a tweak it and and fix it up if you try to to understand what's gone wrong for example in cancer what's gone wrong well it's just a me tayshaun on this particular gene this is a very an adequate picture that we have to try to understand it in terms of like electronics of modules wired together of circuits the around which information swirls of these circuits can become distorted or unbalanced. one political biological theme especially one's evangelical christians in the united states were i do you teach has been darwin if the if one of them picked the book. granted it opened it to see that you were costing down to or at least showing that you had doubts on that over 3 or 4000000000 years the human eye could have been created by doe we need natural selection just tell us a little bit about the journey which obviously saying that we need evolution is

wrong now you say there is a there is a crucial problem yes and i think this is widely recognized i mean it's not wrong it's just slightly an adequate in that case case of gravitation we need einstein's general theory of relativity which is a refinement of that and i think darwinian evolution his original theory has done wonders and so there's a whole chapter devoted to the new biology which is going beyond that and in particular the field of epi genetics as it's called which is those aspects of the g. which not captured at the genetic level but which are very very important for the way the system behaves. so that is now being widely recognised but this is still a battle there are still some die hard reductionist series say that the ultra pure original darwinism is the only way to go and the difficulty you as you rightly mentioned in the united states is if you're dealing with people who want their

religious interpretation of what miracles to put it bluntly is that if you give the slightest impression while there's a problem about the original formulation of darwinism they pounce on the but this is of course to fulfill what theologians call the god of the gaps just because it's might be able to explain something but the fact that science can't explain that there's a gap in our understanding that doesn't mean we want to rush in with god to fill that gap we need a miracle we don't need a miracle we need better suns a better understanding of you the very serious nature of this book and you leave it till the end after talking about information and what the definition of life is in practical terms is a treat. and of cancer. we made off with the evangelical right about their views but actually you seem to be suggesting that a lot of biologists to be believe in a miracle cure for cancer which is not the panacea that they should be looking for

yes i think cancer research is a very good example of how over conservative thinking in biology has not led to lack of progress but the progress has been much less of a 2nd biggest killer. cancer is has also had to become the world's number one killer touches every family on the planet and it's a city tragic of course some people are scared of it and they want something to be done about it i think there's been this naive view that if we just throw enough money at the problem we'll discover a pill that would make it go away and that's never going to happen as we have to be much more subtle in our approach to treating cancer new greenwood sinister ugly when you read the book is us saying that using all this information later years diffused like there was something intrinsic about life in cancer yes it's the nature it's the nature of multicellular life cancer is sort of written into the

whole. logic of life 2000000000 years ago there were just single celled organisms on this planet and a bacterium for example just has one imperative replicate replicate replicate it's in effect immortal and then about one half 1000000000 years ago life organized itself rather differently than these some organisms did ensue multicellular collectives and what happens there in order organisms like selves is that individual cells give up their individual immortality they outsource that immortality to special sit germ cells likes eggs and sperm and they carry the information. legacy into the next generation and the individual so-called somatic cells like a cells in a skin and liver and so on they part of that contract is that they undergo programmed cell death toward a pump prices and cancer is a breakdown of that ancient contract in which the individual cells return to

a bid for immortality worrying about that is. this is all going to be a magic pill for cancer there when each individual cancer has to be treated in its own way a general purpose pill to make it go away i think is is you're on a hiding to nothing if you think a lot of the problem is being capitalism the position of profit big pharmaceutical companies saying we've got to look for this pill because a budget a rich we become i think you're right that the funding model where that we totally capitalism because it is after all rigged market anyway. all over conservative government investments in cancer i should should mention that i was funded for 5 years by the us national cancer institute spends $5000000000.00 a year on cancer research the pope when i look at how that spends a lot of it is just spent on sort of same old same old mainstream research very

little on imaginative new approaches and the approach of i'm outlining in the book . has received some funding but it's a sort of tiny fraction and so there is deep conservatism in the cancer research community. and i give you an example which relates directly to the whole profit business that of course. if you have some way of combating cancer like through diet or. another approach that we've looked at is hyperbaric oxygen therapy which is pretty patients in 2 atmospheres of pure oxygen for a short period the some belief that. some evidence that this is efficacious so one of the most efficacious anti cancer drugs it's well known in the cancer community is aspirin but you know it's fair to be free over the counter. getting clinical trials for things like aspirin is not easy there have been some.

but and little people say this is. well it isn't that because well i believe it is permissible davis thank you and that's it for the show would back on wednesday 50 years to the eve of a more modest after becoming prime minister of libya and jill thank you both by social media don't forget to subscribe to our you trying to. flip flop. the feel. flow. feel. feel.

feel. feel feel. live. play. lists lists. licked.

play. and a very warm welcome to you you're watching us inside. on this edition of crossfire we conduct a post-mortem of the recent us around conflict what has changed in what bodes for the future issues the mainstream corporate media refuse to discuss. descriptions sound up to tasing even for the owners so how to choose just pet food industry is telling us what to feed our pets really more based on what they want to sell us than was necessarily good for the pet turns out may not be a sofa the best people believe we have animals that have you know diabetes in arthritis they have auto immune disorder simple problem of diet and some dog owners

so heartbreaking stories about their pets less treats the larger corporations are not very interested in proving or disproving the value of their food because they're already making a $1000000000.00 on it and there's no reason to do that research. what politicians do. they put themselves on the law and they get accepted or rejected. so when you want to be president. or somehow want to. have to go to cross the survival before 3 of them or can't be good. interested always in the waters in the. question.

it is morally to the live in moscow for talks hoping to we just think try delta and civil war and the all back. 100. although washington warned the wrong and stepped up its pressure campaign of sanction as antigovernment protests continue in the iranian capital over the accidental downing of a passenger plane which killed everyone on board. the u. funds to boost infrastructure in east africa and prevent mass immigration to europe is in the firing line for human rights organizations for driving modern day slavery we speak with a human rights watch representative. you didn't directly supporting the.