1000000 all this before the onset of winter and the heavily infected northern hemisphere. meanwhile, africa means an unvaccinated continent with billy 5 percent of the population covered. while in the u. k, a series of bizarre policy decisions has included delaying the vaccination of teenage school child until after the school year had returned. the results across all ford administrations is that the u. k. one of the highest vaccination rates in the world also now has one of the highest streets of infinity. those who talked for early signs of no kite blue for science over divide us looked at didn't to disappointment. but it's yet look, it's bleak. i think at 1st sight, appear. well, today we've been til was expert perfect or neil of trinity college. dublin has emerged as one of the key commentators on the ability of vaccines to triumph over crowded virus, but fight your troops, messages and emails in response to i show last week. i mean you keep part is constant season session. partition quoted says,

no one is standing up to the today's in this says, the program is very informative. i was never important enough to be authority. thanks. edwina. john carnegie says labor i too much to the right. now. of course chris will infant affect his lifelong hero toward the bed and last week. sure. and i'll newman says tony been was awesome. micro friendly says the english ship of state is hold below the water line. the only thing stopping it from the thinking completely is it makes a public money through an acid. gordon mackenzie says adrena cutty is always of great interest. not necessarily politically or factually correct. but always interesting. and finally, while you're more says in relation to the ship of state ship, more like a punctured thing, a with a captain and clueless cabinet last scene. now the back to the deployed, but the vidas is still ripping through society. we try to profess luca, neil of tennessee college dublin,

profess underlying state to play in the battle between science and the virus does not look at meal. what's happening? what old? why, i mean i, we wedding less battle with throwing a virus out of the black students, the veiling, are the still plenty of pitfalls to come? well, it's much better than it was, i think, last year for a much better place mobile. let's start with that fact, but the change is still burning away, especially developing countries. a big concern is low vaccination rates in the poor countries of the world in the west. call it quite well in europe, especially thing very well. actually. we're getting close to magic numbers. so the magic number now is if 85 percent are vaccinated or have been infected. the really good place to be because you're not getting the granted praise her to me and it's, you know, that we don't like pretty much a certain you're getting a high level of protection in our community. tremendous items. i mean, we're the number one euro and we would like to post this course. we become

a found anything funky but we've got a 92 percent of our population vaccinated on monday and the nothing about a comes near but everybody. well, but let's look at the u. k. i'm the data medica which are relatively high vaccinated countries but have higher rates of the violet, sun, scotland, extremely high rates recently. and england rates are low increasing again. so what's going on? why is it that a high vaccination country can still have relatively high rates? so spread the virus. well, you have in america, for example, loc, the large box. so very often, the cases are in the box. maybe the majority of cases will be in the maximize both you see right, so the actions and maximize well. but the good news is it's not time buddy and severe disease optimization. case numbers aren't especially informative, called the key metric here it's severe disease location. the u. k. scott member

holding study. i'm telling study without numbers. i mean, last week i heard an expert and you have not been overwhelmed now in this phase of it. even though case numbers are all the main increase, hospitalization is important. certainly that we can the link between the spread of the virus and hospitalisation and of course deaths and mortality. but when one of the chief medical advisors, the price will quickly just last week, seem surprised that 50 percent of english school children had been infected with a virus. why should that be a surprise? i now he was hoping mitigation was happening in a sense, you know, because of the skills reopened. they'd various mitigation measures in place and thing and ventilation and maybe hit surprise with a quick number. got infected might be thing you say, remember i like it's not a bad thing because it's already been 9 to even children. and if they get infected, they will be protected. and even more importantly, debbie,

picking up delta one more time. we're going to be protected from reinfection with down so, so i didn't think that was a negative light though. i'm not surprised you because obviously when the schools and you've insufficient mitigation, it will spread infectious chicken pox you know about. now, by the way, delta, by the way, and as you might remember was taken, one class, one pupil gets it, they all got chicken about surprise and you're seeing that level of the one that had been a reasonable precaution to vaccinate the secondary school children before we went back to school as opposed to afterwards, a definite, an ard and we did that, we began my over 12, maybe 34 months ago now. and i think it's something like 80 percent of the over 12 now are, are fully backs and i got a great number to see. of course there are protect it. the next question is, what about the owner? and she'll be back in art about the mom, actually the main number 12, because maxima, you see, so i'm not tells us something. so whether we should move on and maximize another.

another question, we're still thinking about school children, some suggestion and settling the u. k. the only be getting one of those of the 5. how do i, how does that make sense? professional in the strain in art and again you don't quite sure whether you went for one both. i think it's because they've been inspected because one possibility and then i get back to your shop and then you get your fresh like a 2nd shop knowing that may be the reason for that. but it was an interesting that they kind of seem to give it away, maybe to the developing rock and never, not an art. and we get to shop. it's possible to, to choose from all this range of vaccines which become available and record quick time is one of 2, a matching us the as the clear front runners in terms of be efficacious as of a medicinal compound which is efficacious in every case. yeah, there is not a data as amazing. i mean, we've never studied a virus much of history,

the amount of knowledge we have in the past 18 month on the, on the side. probably 2 of ours is remarkable. let's start with that. the science behind it. tremendous, and then the vaccine deployments, a measuring vaccine performance. and so something like 5000000000 people in the world that the number one shot made. and then many to shop on different boxing. you know, the title likes to be madonna. seems to be number one, and then we have 5 or the are and i have seen are really for me extremely well. and then we have what i call the no viral vaccine, astrazeneca johnson and johnson. so there are less affected than the, okay, i'm in the beginning, 6070 percent protection. but what's really great is going to be an ologist is we may have come up with a technology for any of the these using our m, hey, of the technology. and as we speak, alex is a try an h i v with an already seen. so in other words, they manage to devise

a technology against a very powerful vaccine and not seeing technology can never use. but other infectious diseases. we're still remaining here, he's problem malaria on the list t b. is that a big problem? some of the axes are definitely i law i, we got the same level of statistics across a little bit. how does the, the russian vaccine the spring getting on? how's the chinese vaccines heavily performing world white? they're similar to last, rosanna. now like all the fashion that like almost technologies. so it looks as though the old fashioned approaches are still working. we still use those technologies and different vaccines, but the are in the novel ones that are performing them from the 2nd concern. we have the waning amused, so which of them is waning faster and there's no doubt size there are holding up more than the others? no meaning, again, that's more evidence that the more powerful advice for these more traditional students cannot be dealt with by the so called boost of jag,

that's the thumbed sort of evidence that once you get to that, then you have the effect of perhaps not complete, but effective immunity arrays, great data, again giving 5 or after within a cafe or vice versa. and on across the board. it's august. immunization is the fancy name for me to change the vaccine with the 2nd job. you know, now heather august is always better. you think of the sense that part of it to the shop for the of the, the same shot. again, you're like, the last, you know, give a different shot. you get a better response on the data. how are not one and it looks as if there was a follow up line. that's a really good combination and you get a very strong response then i believe from not just right to the softener the u. k . but in other countries are only using or, and i back saying that the booster shots because they know works better than giving it was because of the case, the vicarious. a good idea to mitchell says that we'll send it to the great when the great and easy. all right. and how is that?

even if you've had to vaccine shots, you can still end up in the hospital. lots of people find that very difficult to understand. sure. well, i mean something back saying, work and not individual for summary, any minutes symbol show variation in effect between a whole lot of you know, so sadly some are vaccinated. for some reason the maxine hasn't worked it and then i'm not going to happen account because the patient already for some reason or whatever it might be and the ones who die. sadly, they offer all the diseases while underlying conditions or make an especially, you know, in other words, nothing were 100 percent, everything like that. we'd be happy. so sadly, the small minority who do actually end up having the maximum for somebody in your field. i mean, obviously this is a comprehensive human tragedy across the across the planet. but you referenced that we've got this unbelievable data in your professional career that you ever believe

and your discipline. and you would have such an amazing mass of extraordinary data about ariel the some, but any fibers staggering back to him and it was obvious the well justified me, we got the biggest damage on the years. you know, everybody that we'll all the drug company, many academic my own lab, we switched into cobra to work on specific because of this, you see, i was in a conference last week in jeremy. my 1st conference in the year and a half and you believe it face to face the excitement with tremendous every talk about co, with in the bar in the restaurants. always any knowledge of cobra over over prophecy for good reason. i'm not eating all this information. so now we have a tremendous body of data by corona virus. and in general, we've got new ways to deploy vaccine. the most up thing we have, the 3rd thing alex's new therapies. remember, because people often forget about hospital trading. some island rights gone up as

well. and it applied to 7, you heard a few to approve for you, and if you end up half of it, again, that was all this massive effort. now katie, this is going on with all of it. we learned a huge amount about all the viruses about the immune system over decades, an offense we where we deploy that knowledge and then learn even more in the remarkable, remarkable achievement, the science with professional looking deal. when we come back in a few minutes, we'll look at some of these new therapies and see how the effect of the the look forward to talking to you all. that technology should work for people. a robot must obey the orders given it by human beings, accept where's the short or conflict with the 1st law show your identification. we should be very careful about artificial intelligence. at the point obviously is too great truck rather than fear i would take on various jobs

with artificial intelligence. real, somebody with demon a robot must protect its own existence, was only a ty, now where we received so many inputs on a daily basis that are completely related to reality. so think about how in social media filters and they basically were present themselves in very unrealistic way. and so we come out of fomo, there is and be involved more than that. it's about being sort of envious of something that may not exist and is also really tied to the fact that as humans we want to be part of the crowd. welcome back. alex is in conversation with professor o'neill. the vessel, neil,

you mentioned how much more effect of treatment swell, the famous one, the president trump was administered, not experimental phase which was seemed to what one does for the, for the president. is that the sort of treatment that's coming for it is number one . so that's called antibody therapy's. mama fall antibodies to give it a full name. what they are, their antibodies. you've inject into your body against a spike protein and then off the spike, and then stop the virus, stick it into your lungs. you know, it's been you not the disease in the right experimental came out with some talk, them bare decreasing by 70 percent. incredible. and the 2 types one by regenerate by lily, and they are approved in the u. k. by the test, for example, the very huge advance is not a problem with the right expense because 2000 your i was shocked for example, to take 90 minutes to infuse so it's a bit boring to say, but yet again,

so and also serious today's, the doctors can i give them those antibody therapies and talk about a face and experimental when you're working? by the way, because we use the vaccines call us, bring them at anyway. here's an interesting one. so anti boxes in america won't take the vaccine, but they will take the money that they offer and it's costing a $100.00 times the price. so you see a proposal to dr than americans that have the same concerns of the because it wasn't actually taken the strain of those antibodies. are you saying if the former president was still allowed to tweak? he'd be saying how he saved the planet to an experimental level. yes, i suspect the pain, successful. se, probably said the inventor of them. certainly, there are really important thing is they divert nurses away mother in the us at the moment in the southern us states. their basic and the last thing that was quite low, but they are using all the strange when you think so. the question is,

how many companies make more of them? will the price come down and so on? because you want people to access the, obviously it's a danger, look a deal that with the effectiveness of the back seat. and once people get to jackson, even the free jags, the lose all sight of the public health measures the, the more traditional way, the ancient way of tackling a disease outbreaks. i think all of us will have been to events recently, perhaps not medical conferences, like the one you mention, but other social events where we find the sales, the only people who are wearing masks, for example. you know, it's true that a bit of complacency begin in a sense, you know, not understandable because remember, this is your heal, if you're vaccinating you are now huge protection against the virus. tremendous. you know, so people going to all of my life. i couldn't, you know, but for this next phase my, she'll be in the winter in

a bit of caution. we need that many on back tonight, including all the children so vulnerable people on the waning issue is still there . we're still very much in the middle. and remember the respiratory disease and we know cold and flu spread in winter. where do we have now is it can be some kind of surgeon. sure. so again, we need to be cautious in the coming months. got to spring different story out of the winter than and then maybe we can really begin to think about the traditional enemies and viruses, the colds and flu. so i saw some twitter traffic in the conference season with some journalist whitening that they've got a heavy cold. that conference is not corona virus, but a most traditional infection. how do these traditional infections interact with a major, vital spread? does that make you more or less formidable to these? we think people are what we call my eve for those viruses now because they have been out and about for a month to month on it and you know, in other words,

last winter, we all stayed home. we didn't catch the things and i don't. immunity began to fade . i mean it's a strange business, but sometimes immunity go now this winter or back out in the field, if you will. and then we start catching them again. and i might be fighting more severe because you know, defense or limited defense against them. so one prediction is we will see more severe calls of hello, how are you? it's just a bit of a news, you know, the flu you want to watch for next. and one of the worries we have is that can be taken in flu. ready cases again, simply because people have lost their immunity to some extent against the flu. so again, the vice alex very simple. get your flu job if you're over a certain age and i wonder because we get to through your job and get your booster with the same time. and that's actually happening. we're seeing my phone companies are putting the 2 shots in want to make it easy. you see, so flew with an important information coming into the window. so i should be asking my own position over the next few weeks of i can get one short rather than one that i that are. is that right? yes. if i still want to be lucky, you never coming to the the serious possession what or why even more serious

possession. i mean africa as a continent as a level of about 5 percent. fact sedation, the present moment rather than 9 to 5 percent vice lazy that 95 percent unvaccinated. how to viola frey left is to the whole of humanity that such a continent is unvaccinated. it's a huge, it's a big issue now i see that the last remaining significant concern is extra variance cropping up and coming back to haunt us if you will, you see. and they could pop up and africa. a variant happens because the virus survives and makes a mistake and you get a slightly different buyers with a random process by the way. it's like, you know, rolling the dice. sometimes you're all the dice and you get a nasty, very delta is much more transmissible for example. so the way to stop the variance is to get the viral account down and pay for the vaccination program. so we must get vaccines for now. it's about up in country the 2nd,

even more important reason that is ethical, that people die in those countries of who will be protected with vaccination like health care workers, vulnerable people and so on. so we want to get the vaccine. now everybody know this, governments are on anything, lots of i've seen the u. s. axis where to get 500000000 dose in the way again. and the u. k is as well, so we are aware of this. but now it's a case of mobilizing us and making sure we get as much back soon as possible for those developing countries. and it's more of a logistical question that even a manufacturing question may be a quest, a licensing manufacturing in other countries. but the key question is, logistics, the sort of logistics that human kind of seem quite capable of mobilized and for warfare, that logistical support seems beyond us for, for distributing vaccine wires that it does not know they are aware of that as well . so in the global production, in the next 12 months will be $22000000000.00 for the vaccines that will be made, not smart enough to vaccinate the world. so the question never get into the trucks

. get out there, you know, get out for these remote places and so on. and then they're aware about that are quite right. it becomes just to go exercise. now we did a smallpox in that we've got vaccine all over the world eliminated. we've almost film at polio in africa now, africa, polio, free. and again, that was just simply getting the maxine into all these different places, you know, so can be done. and now more than ever with this, we must do it. can you imagine if you very across top dogs the same, we're back to square one. now we can get another maxine going of course we can, i can imagine the it's like a logical effect the economic effect. so it's a really important issue to get to get the vaccine was like that the bill of factories in these countries to make the boxing. and that's a possibility. but it's something that now and jr, for example, it takes a few months to build one of these plans because labrat, obviously enough, india can make billions of doses already. they've got very elaborate production there for the vaccines. so you may, the future may well be building places in these countries to make sure the supply

is not an issue. and again, it's local. it gets that much more quick. so a production is not really the issue is more distribution than logistics than it is a false tradeoff. is it not to say there's a balance between a boost of jargon they developed countries and any jag in the, in the developing countries? it's more a question of the company is getting their act together and getting jags into the arms of people. what, wait. you know, the dilemma now is should you have a child the vaccine where not shot a minimal chance of dying or give back to a high risk of dying and that person might be an older person in the developing world. you say the ethical christ, the, i think the answer is give it to the person who is at risk of 9, not the one who you know. so in other words, if the body is not an issue, we should get everybody done, you know? but if supply is an issue, you shouldn't, given the children had somebody on the left to be that will be on the back or

having, i mean, they are thing, tony the payments, american immunology, last week, you said they would empower, consider, you must do this and don't just do the boosters in america, you know, make sure every day. so you get to give a shot to developing countries. i'm not alex well they do, and i will they manage to do this or not? you see, that's the question that we now have seen as you've described, giant leaps for human kind, both in the development and rapid, quick time of black ceilings and in the, the better treatment. the acute treatment for f. a coven, other fun the steps to come other yet more technologies which are going to be devised, which will give us a better chance of, of defeating the same enemy? well, you won't believe it. it could be the max things are so fantastic. that was good. it's going to get and it's very good by the way, you know. so we may well, not quite stumbled into it, certainly serendipity in science. i know we managed to make these are and i and

they seem to be sometimes. so if that's how we would deploy those things against other infectious, even cancer. i mean by on site the company which gave the vaccine to 5 or they were actually going to counselor to make it back same for counsellor. can you imagine that the doctor isn't among immunology that we now finally get vaccines for things that we need vaccine for, you know, the period if we need to do better now, even though that 70 percent is a great number, are still very expensive. hard for me. you know, so we may see a better production situation, but he has one option. and then 2nd to my own area promise we were trying to develop much more power ways to suppress inflammation in the lungs in cold. but for example, those drugs could suppress inflammation and other long diseases like emphysema or you know, so the words are going to get my analogy. i really got something from the print shop. we could get technology from it that will be deployed and lots of different

content, and i think we're going to look at it like the 2nd one. okay, right below the new technology that we're flexible across different areas. the co crisis unsure when we look back and came back. christ can be used in different ways . so can pin you down on this. what you're saying is because of the extent of the technical breakthroughs, the, the fact that we know from the large sample of application of the vaccinations from the significantly increasing sample of the treatment, the medical benefits are such that these will be a clickable to other diseases to other conditions that will be not unable to defeat in the past, but these may be break, prince for the future. that's the hope exactly. look or malaria. i mean, there is a disease that devastates africa. you know, we spent decades trying to get a vaccine. now we're seeing progress, you know, if we, if we can get it malaria from africa, it has massive economic benefits because,

you know, on the health of the nation is better, people are getting sick and so on. yeah. so, so the 1st time, maybe us oversight commitment area for a few years actually. but now it's within our grasp states to develop vaccines for very important infections of data. and that was deployed. and your previous getting them i was, you know, can you get the vaccine out to the people or not, you know, and we, if we lay down the tracks, they get out, you know, things that may be sold, you want to grow. so, corolla virus, a strongly pandemic, huge number of casualties. what'll white but the end result? maybe a giant leap and science. yeah, definitely. and again, you got to get credits are many years investment research in the welcome. in the u . k. for example, they might have in the u. s. they were all, you know, tax payers, money off and was spent. were now seeing that coming gotten away because we didn't know the vaccine would be a really bad way because you'd be looking at an awful lot more death and

destruction. i'm not the case on a bill on all those years of research professor look at neil. thank you so much for joining me once again on the alex simon show. lobby. thanks so much i in recent weeks, 2 of the highest back committed countries in the world. the us and u. k. have record of the high streets of krona virus. it is true that the vaccines have weakened the link between infection and hospitalizations, but the us, the store recording the highest number of deaths in the world at over $10000.00 per week, while the u. k. as one of the highest, in fact typically dates per head of population. they almost block a reaction of substantial sections of the population and media to this continuing level of infection and loss speaks to people bravely and the societal restrictions . however, both countries are heading into a northern winter where conditions are conducive not just to cruel of iris, but to other winter killers. and both countries have health services already

buckling under the pressure of the virus. in the circumstances, the news to mister vaccine shots and further protection from other therapies such as the antibody cocktail developed by the general and it's understandable other policy decisions, however, seem inexplicable. as many parts of the plan is to largely unvaccinated. any suggestion that humanities battle against corporate 1900 nearly won the pen maturity of extent of foolhardy for now for alex myself and all the show is good bye. stay bases. i'm hope to see you all again next week. ah me soon?

ah ah ah ah, [000:00:00;00] ah, jamie diamond was critical, a big claim starting when it was a $200.00

a coin. it's now around $45000.00 point depending as he points out. 10 from here. so he's looking for up to $450.00 to $5.00, and about a coin the it was an extraordinary disaster. if we didn't have a president, that was so addled. you all would be fired. i don't think anyone contrast anything this present says about afghanistan, us lawmakers and scold joe biden, and he's tell us several in congress holding washington humiliating withdrawal from afghanistan. we are so if the whole of gun campaign might be a bigger failure than just to pull out itself. also this the rule of shame that the graffiti spelled out. i'm not how some harris have come to view this