yuri hello, i briefly reminded you that the entrance to the shebekinsky urban district, where the village of volzhanka is located, is closed until june 30 for any type of transport for road and rail traffic. there is no governor. indeed, he confirmed that there were battles in the new tavolzhanka and , uh, for the past month the entire shepetinsky district has been shelling, but the last few days have stood out for the ah-a new volzhanka for shebekin, especially the terrorists, probably so tense today, the ukrainians laid out everything this video, in which, against the background of prisoners allegedly of our e military, they told that e was ready today e, they turned directly to the governor of the belgorod region to exchange. ah, and they said that he personally could participate in this. and let's listen to the answer of the governor of the belgorod region.

ah, it’s worth saying that uh sips of the governor sips reacted to this video e he didn’t say that it was possible district, but at the same time, of course, there is no confirmation that this video was not filmed in advance, that these are our fighters, that they are generally alive, uh, nevertheless, according to preliminary information, which has not yet been confirmed, there are about 20 people in as part of this sabotage intelligence of his group. defense. there is no technology yet, but artillery strikes are carried out both by barrel artillery and from rocket artillery. uh , a ukrainian sceptzo is working on the network, distributing a video, allegedly shootings are already in the line, and the newest tavolzhanka. this is until e confirm the video, most likely, this is an element of such a psychological struggle of people, they are really trying to intimidate. and at the same time

, it is worth noting that shelling is also taking place in the engraving district, and we have recently returned from the village. and kazinka there today it was several times subjected to mortar shelling, mines lay next to residential ones, but fortunately no one was injured in the houses, but in the village itself hmm few people can be seen literally there are several people living there. at the same time, there is no light, shops do not work. there's only gas, we'll be watching closely behind the events and inform about how the situation is unfolding, including in the new volzhanka and in the shebekinsky urban district yuri thank you , we are following what is happening together with you. let me remind you that my colleague yegor grigoriev was in direct communication from the belgorod region. and in the minute in vienna, the ministers of the country are negotiating the pluses of official statements. what exactly was not on the agenda, but news agencies, citing their sources, report that we are talking about an additional reduction in volumes oil production, that is, now the capital is directly connected

austria, our special correspondent alexander suvorova hello alexandra. what is known at this moment of negotiations? yura greetings, but so far it is known that they have not officially started yet, in fact , the internal discussion has been going on for the sixth hour. and so far no ministerial meeting of guardians. plus, not only the committee, which was supposed to be before the meeting itself, had not yet begun, and at the very beginning, even before the start of negotiations here at about 11 o'clock local time, passed by. our colleagues asked the minister of saudi arabia what on the agenda? let's listen. you can't even imagine what we are discussing. therefore, now there is different information about what exactly the rapper is talking about. the day before, the rapper wrote that they are talking about discussing an additional reduction of one million barrels per day in total for all countries. whether this is true or not is still unknown. i remind you that today was supposed to take place at the beginning of the meeting,

where they discuss the current state. ah, the market. and if we talk about quotes, they still do not react in any way to the fact that brent oil costs around $76.5 per barrel. well, after that , a meeting in the expanded composition of the guards was already planned. plus, where, of course, they also talk about the situation on the market, i also know that now there are already three ministers from those countries that are members of the association. left the headquarters of the opec for the moment. here we are working. just opposite her. this is the head of the delegation from gola gabon. and libya well , the last minister still promised to return. so we continue to sit behind the development of events. oh well, we are waiting for alexander i i thank you for the progress of the talks between the country's ministers. uh, then, how the negotiations are going here is being monitored by our correspondent alexander suvorova and now a small advertisement, and then watch the documentary . kurchatov institute medicine of the future of the latest technologies. only in

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perspectives are opening up at the intersection of modern chemistry, physics and medicine of the 121st century. this is primarily a turn towards biotechnology, when innovations in the field of medicine will fall into the hands of doctors and will be applied in practice. now that brand new materials when a serious institute took up the development. and our tasks. i hope this gets implemented. is it possible to grow living tissues in a test tube, cell technologies can even come to almost any supermarket, research and development for the medicine of the future are already going on in the laboratories of the kurchatov institute today, and as it turns out, this is not only interesting.

november 2022 moscow, on the stage of the zaryadye concert hall, the winners of the entire russian award for fidelity to science are awarded among the contenders for the national victory research center kurchatov institute and the first place exhibition of photography science is beautiful, kurchatov institute. the victory in the science as art nomination was brought to the kurchatov institute by a project called science - this is a beautiful collection of photographs taken by employees of the research center right at their workplace during scientific experiments. our scientists are involved. they see pleasure in their work.

they see how beautifully it penetrates the secrets of the microcosm, and it really turns out sometimes amazing impressionistic pictures of both the microcosm and large installations and physical phenomena, therefore, and about the decade. e science. i think for the next 10 years. we have many, many more interesting things. thanks again from all my colleagues the idea of ​​the project was born back in 2018. during this time, hundreds of pictures were reviewed and the most interesting choices were made. bacteria nanocapsules protein crystals particles of polymeric materials, as it turned out under the camera's eye , they all look like real art objects . just microscopy. yes, and plus it is also necessary to touch on various mathematics, too,

the structure of the protein will stop. there a priori, a very important topic, so they are still very actively involved in everything. this is how, in a rather relaxed atmosphere, the selection of the most interesting and striking shots for the project takes place. science is beautiful. here is the photo, as far as it was taken on a regular phone. yes, and there is a special ordinary titanium foil, but still in europe. that is, this is just the beginning of the development of the brothers, because, uh , the project allows not only to use. with him, but he actually shows the scientific world, in a simple way, that is, what scientists see here is a simple person, he does not see such a foil in life, and it is unlikely that when we say nuclear medicine people have in their heads x-ray irradiation of the installation and so on, and in fact, this is where development begins for the sake of drugs for treatment.

today, many areas of work of scientists of the kurchatov complex nbx nature-like technologies are associated with biology, genetics , medicine, together with practicing doctors , scientists of the national research centers develop new materials, approaches and technologies for modern medicine, few people know, but the kurchatov institute began to engage in research related to medicine almost from the first days of its creation. when genetics was destroyed in fact, uh, all the outstanding geneticists were collected by kurchat, then you are strongly aleksandrov , and as a result, we, uh, in the fifties had one of the iconic powerful genetic research centers in the world. now, if we talk about the origins of nuclear medicine, then

forties. we studied the mutagenesis of the so-called living organisms that were studied. what about the effects of radiation? we have been actively involved in this. this is the next step. it is. forerunners of nuclear medicine. fine. should have seen. and how it works, what happens in genetics , they did not know how to decipher, but genetic changes could be observed in different ways. and what is the main thing in medicine today. the first is diagnostics, a unique high-tech x-ray. ultrasound mri is all that came out of science in particular from atomic project. an uninitiated person will never guess what is depicted in this cosmic-looking image. this is not the lunar surface at all. and a photo of a sphere using polylactide, made on an electron microscope

, polylaxide, a natural polymer, which , according to experts, has a great future in implantation, life-size microspheres look quite prosaically a simple white powder in a microsphere test tube. they are quite interesting they have a porous structure. they are very light, and contain about 95 percent or more of air. we we can make them bigger, right up there, yes, and these particles are millimeters. we can make them very small. in this case, i now have particles somewhere around 100-150 microns , and these particles turned out to be quite good, but a filler for various materials, including, first of all, perhaps for hydrogels. a mixture of hydrogel and porous filler is actually plasticine , which can fill any bone defect . this technology is indispensable in maxillofacial surgery in the case when, due to the inflammatory process, part of the bone

is destroyed and it is no longer possible to install an implant in order to restore and replenish this tissue, but it is necessary to use osteoplastic material. one of these materials is being developed in our laboratory. the main advantage of natural polymers is biodegradability. that is , after the material has worked its way, it decomposes into the simplest compounds and is naturally excreted from the body. in addition, the polymer can be given a different shape and volume. this item looks like a piece of foam, in fact high-tech products that scientists in the laboratory of polymeric materials have developed at the request of pulmonologists. the so-called bio-filling for the lung, of course, does not perform the most complex functions of the lung tissue, so it cannot be considered a full-fledged implant, but it is necessary to restore

the functioning of the respiratory system, when surgeons remove part of the affected lung and it is necessary to fill the missing volume, it was not needed quite large in volume such a construction up to half a liter, which at first, uh, would not put pressure on the lungs, would not be too heavy, but at the same time, the then sprouted to connect with a copper cloth and stood as a part of the body, and then naturally biographed. we are already doing this kind of work, even doing experiments on rabbits on dates , the result of positive tasks to replace part of the lung turned out to be not easy. scientists managed to make a filling, almost weightless only four percent of the volume is occupied by the polymer itself , the rest is air. to create such a refined material, experts used the freeze-drying method. another one an installation with which scientists plan to obtain living tissues, or

even entire organs, right in the laboratory. a 3d printer, but not a simple one. and with the bio prefix, this time it performs a non-standard task - it prints a three-dimensional emblem of the kurchatov institute. moreover, from collagen, this natural protein forms the basis of the skin of the cartilage tendons in our body. true, such a souvenir cannot be taken away with you as a keepsake. collagen requires special storage conditions; layer by layer is applied by the printer and repeats the structure of living tissues. so you can print the basis of blood vessels , create a patch for a sick heart, get artificial skin, in fact, different cells. now we need to take this knowledge and

make the same frameworks, they are called and, uh, then. if we then put it there, then the correct cells. they can give tissue, organs, and so on. these almost invisible threads that look like cobwebs are also made from a natural polymer. in this case , chitosan. it is found in the shells of crustaceans and the chitinous membrane of insects due to a thin capillary. solution comes out applied to the capillary. high dc voltage under this voltage, the solution is drawn into a thin stream, further this stream can be split. you can clearly see here the solvent, in the meantime it evaporates, and then the already dry polymer fibers deposit electrons and thus. here we get non-milled materials by a method called

electrospinning. and although it was discovered more than a century ago for medical purposes, it began to be used relatively recently and the prospects are obvious here, and creating materials of the product, there or an implant of some kind by such a method. and we get the very architecture of the material into a surface morphology, uh, similar to the native tissue of the body, and thus such materials, then later on it is easier to take root and are not rejected by the body. for example , a medical bandage with unique properties can be obtained from biopolymer nanofibers. it protects against infection, while it does not get wet, does not adhere to the wound and is easily removed in cases of extensive skin lesions, as it is an indispensable thing for burns. scientists even developed a portable version of the device for electroforming everything you need fits in one compact suitcase. oh well, here we got the non-woven

material right at hand for such emergencies, if urgently needed in the field without installation without electricity connection, but, in principle, it is possible to cover an area here. there are even several hundred square centimeters. here 's the method. well, further already a person to transport. uh, to the nearest hospital there. to further resolve this problems. in addition, fragments of a matrix of blood vessels can be made from nanofibers; for this , a non-woven material is sprayed onto a model printed on a bioprinter, a hollow tube is obtained from a biocompatible polymer of the required shape and diameter . the next stage of research is to find a way. how these artificial fabrics revitalize matters. how to tame living cells and create all the conditions for their reproduction is done by specialists in tissue engineering , if so, well, basically. ah,

engineering fabrics, that is, they are constructions that are a replacement or model of real living tissues of the human body, but, that is, they are developed in such a way that a we isolate the cells of any tissue that interests us and a well, seven of them on some kind of suit carrier, the so- called here that is, in which these cells will always feel good for experiments. living human cells are obtained from skin fragments, for example, arising after plastic surgery and patients consent to use these cells , they are seeded on a special polymer matrix composition and sent to the incubator, where the temperature of the human body is maintained, and after 2 weeks directly in the cups. petri grown stands faux leather. outwardly very

similar to the real one. on artificial skin , it is possible to model various diseases and test drugs, and partially exempt experimental animals from this mission. in addition to skin cells, biotechnologists grow in vitro more complex types of vascular, nervous or muscle tissues. how a living cell feels, planted on a polymer frame, you can see with your own eyes. eyes using an electron microscope, for example, this cell in the picture, everything seems to be fine. if you like the cell-machine gun, it will try to try to grow, if you don't like the polymer of the cell, but i can try to separate. here is a photo taken at the probe and electron microscopy resource center. kurchatov institute also got into the collection of the project. science is beautiful. electron microscopes are one of the most

demanded devices at the institute; with their help, you can immerse yourself in the microworld, see, how materials and even living cells are arranged at the atomic level there is a manipulator needle that can touch the sample and extract some sample of the sample from the base. and for further research, that is, literally precision work with materials. we can have some separate small place measuring 10 m - this is 1/5 of the microscope. one of the premises of the laboratory resembles a space flight control center. it's hard to believe, but this huge installation is also a microscope, namely a cryogenic, transmission electron microscope, by the way, the only one in russia the name corresponding to the titanism of the electronic microphone.

here we can see the main parts - this is the source of electrons, which is then accelerated to an energy of 300 kg volts is projected onto the object and then , using a lens system, the image is enlarged and gets on a highly sensitive camera. shooting biological objects requires special conditions, because under the influence of a powerful electron beam and the vacuum used in the microscope, the structures of living cells are destroyed . in addition, the sample itself must be transparent to the electron flow. a thousand times thinner human hair. to do this, we need to create a very thin layer. uh, water, which contains, uh, the objects of interest to us, and so that this film does not collapse. especially under vacuum. she needs to be frozen. uh , we blast freeze liquid food and we actually have, uh, no

ice crystallization. during freezing, it turns out that there is no depreciation in which individual molecules are embedded, then we stuff them into a microscope and examine the structure of the object very close to the native one with the help of titanium, scientists investigate sections of living cells study the features of the work of ribosomes of cellular organs responsible for protein synthesis. the study of one sample can last a whole week during which time the electron microscope will take tens of thousands of individual images. after their processing by a computer program, one high-resolution three-dimensional image will be obtained, a picture worthy of the cover of the best scientific journals. this photo also took part in the exhibition of the science is beautiful project. although it was obtained using a simple optical microscope, there are small spheres in the picture. on

in fact, complex containers made of a biodegradable polymer, inside which there is a drug, such developments are carried out by specialists from the nanocapsule laboratory. we form. uh, carriers for medicinal substances. these can be various capsules and containers of particles. uh, we load them, uh, active substance, and then we study, in principle, how this active substance will behave in certain conditions. that is, we must understand how stable this capsule is, then how this active substance will be released from our capsule or particle container has long occupied scientists, because an ordinary tablet goes a long way before the active substance enters the desired organ and suppresses the focus of the disease, while healthy tissue suffers and a lot of side effects appear.

today the main path of medicine. this is the so -called personalized medicine. what does this mean? here we are all the same people we are the same. yes, globally, you need, firstly, to be able to decipher the full-scale genes of $ 3 billion, first then understand and understand what part of the genome. for what it is responsible, and then to study and further we move on to predictive and personalized medicine based on knowledge of the genome. in 2007, we have more than one person in the country. i didn’t know how to decipher, there were no instruments, no knowledge of decoding the genome. yes and so we created the conditions of infra. tour at the institute here and deciphered for the first time in russia the first russian cynologist - it was the seventh in the world in 2008-90 and since then we have ensured the sustainable development of genetic

research in the country, in which the kurchan the institution is the main scientific organization, the head of this program - this is the basis of knowledge of the genome of modern medicine. so, a detailed knowledge of the passportization genome, genetically, will make it possible to move on to a specific selection of pills , such a medicine is suitable for you, and this person has another for the same disease. gravity drink i'm not ready to eat the attraction of my combo shebekovich's star combo for 325 rubles. only in alfa-bank a loan for business up to 50 million rubles. for one more day for business for 0 rub. with free service

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