this is "nightline." >> tonight, extreme detox. new age daredevils getting all hopped up on frog poison to cleanse their impurities. >> i felt like superwoman. >> we're in the deepest, darkest jungles of peru on the hunt for the fabled amazon tree frog, extracting its toxin believed by some to be a natural remedy, and putting it to the test. >> my eyes feel like they're about to jump out of their sockets. plus 15 years after of this fling on "friends" -- >> my god, this is the most comfortable couch i've ever sat in in my entire life. >> alec baldwin and lisa kudrow are together again in the animated feature "the boss baby." >> who are you? >> let's just say i'm the boss. >> love conquers all. don't you think? >> no, i was choked up by the

end of the interview. >> how they say this movie's message hits close to home. and once the chiseled gladiator. now russell crowe is a victim of body shaming on social media. what he's saying about his fuller physique. but first here are the "nightline" 5. and number 1 is coming up in just 60 seconds.

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good evening. and tonight we are on an adventure to the heart of the peruvian amazon. there you will find a frog whose poison is said to possess healing qualities. but the key word in that sentence is "poison." so why are so many people going all this way to take all this risk? here's abc's mariana van zeller with the latest installment of our series "into the wild." >> reporter: in this other-worldly darkness of the amazon the only thing one can be sure of is that you're being watched. all the sort of most dangerous creatures, the poisonous snakes, they all like to come out at night. look, a fish just jumped into the boat. we've put ourselves at the mercy of the untamed wilderness. whoo. in search of a fabled amazonian

tree frog that has long been used by tribes here. we'll see how long it takes to find this frog. now in high demand thousands of miles away in the hills of los angeles, where ceremonies like this one have become the latest cleanse trend. here these people are poisoning themselves with the toxins from that frog. >> so just remember the breath is your guide. >> reporter: called kambo or sapo it's applied to burned skin and absorbed into the bloodstream. >> kambo is something very unknown. >> reporter: this process is not for the faint of heart. >> you have to have a sense of courage to come here. >> reporter: as you can hear. >> throwing up. the effects of kambo. >> reporter: practitioners say it's worth it. >> i felt like superwoman. >> reporter: claiming the process can help cure depression, drug dependency, heart problems, high blood pressure and gastrointestinal issues. >> i believe everyone should go

through this experience at least once in their life. >> you are basically putting the poison from a frog into your body and your system. did that scare you at all? >> it did kind of scare me. but i kind of trusted something, my intuition. >> reporter: right now there's no research indicating benefits to human health, and it's not officially classified as a medicine. there is no regulation of this treatment by the fda or other authorities. do you think there are any dangers associated with kambo? >> like any medicine, if you take it and do it with no knowledge there is obviously more danger. kambo requires a certain amount of preparation. i would say it's not wise to do kambo if you have not done it before alone. >> reporter: kambo is legal in the u.s., and the people here seem to think it's working. so we decided to travel to where this ancient process began. to the amazon rainforest to see if we could actually find the creature at the center of this craze. >> it was a very early morning. we woke up at 5:00 a.m., took a two-hour bus ride, and then

another 2 1/2-hour boat ride, and now we're here in the middle of the amazon, taking this motorized canoe another two hours up river to the campsite. >> gracias. ♪ this is the dry season. so we have to take the long way around the river to get to the campsite. but now he's saying that 90% of the tourists that he brings out here are coming to look for the amazon's medicine, and he's saying recently they're looking for the frog. so we're going into one of these little shortcuts, these little tributaries. there are thousands of these little tributaries all around the amazon. having been to the amazon a few times before, i'm always struck by its beauty and its challenges. >> gracias. >> reporter: it's the dry season here. the river's really, really low.

so in this case we had to get out of the boat so they could pass. after getting stuck a few more times, our two-hour journey -- >> gracias. >> reporter: -- turns into three. but finally -- >> and we're here. which is where we're spending the night. >> reporter: joining us on this adventure is peter arnold from switzerland. >> so you did the kambo, the sapo? >> i did it, yeah. >> what was it like? >> you throw up. you feel very sick. you feel like you're going to die. and finally it's going away, and after that you have the kind of feeling of being relief. >> why did you decide to do it? >> it was a unique experience. i just wanted to know what it feels like, you know. >> reporter: my team is getting curious about this experience too. but to do that we have to find a frog. >> the sapo comes out at night and usually only when it's really dark and cloudy nights. >> reporter: as twilight settles

it's time to start the hunt. >> we have our snake boots, our headlights, our mosquito repellant. okay. and the rule of the jungle is that especially at night you don't touch anything. a really shallow spot so we have to get out of the boat. be careful where you put your feet. oh, look. not our frog but it is a frog. it's been almost three hours. we haven't been very lucky so far. so they've decided to park our boat and head on foot into the jungle. i hope they know their way back to the boat. oh, wow. look. there it is. that is amazing. big, huh?

grande. >> reporter: here we hit the jackpot. we find not one but two frogs. >> at night they just sit there, don't do much. during the day they're camouflaged so, it's almost impossible to find them. >> reporter: on our way back we almost lose someone on our team in the process. >> reporter: jasmine, our producer, just lost her boot in the swamp here. with luck we easily find our way back to the boat. >> three hours, we found two frogs. heading back to camp. and tomorrow's the big day. >> reporter: this camp is owned by amazon explorer peter gorman, the man o'who claims credit for bringing sapo to the united states. >> somehow just seemed to explode on the scene. it's the emerging stages of a small but legitimate phenomenon. >> reporter: as treatments from the amazon like kambo become more popular, gorman says one can't ignore the impact it could have. >> i don't think any indigenous

group in the amazon is large enough to be able to handle busloads of tourists coming in. i think that would destroy their entire way of life. >> reporter: the next morning it's almost time for to us try for ourselves. but first the toxins must be extracted. >> they just have these four sticks. they open up the legs with these strings and then it starts secreting its poison. >> translator: all the secretion you see is protection. after this the frog will be a little weak. we free it, and it will eat to recuperate its energy. >> i get a little quality time with the frog before he's released back to the wild. >> it's cold and sticky and wet. and they say you can hold it, it's not harmful at all unless you hold it and then you put it in your eyes or your mouth. [ speaking spanish ] okay, little buddy. >> reporter: while the frog regains its strength it's peter's turn. the frog poison has been dried onto a stick and in the

traditional amazonian way reconstituted with spit. >> what are you feeling? >> it's like heart pounding. that's a start. >> so i sit down? >> reporter: after making it all the way here, i can't back down now. >> in 15 seconds he says i'm going to be able to feel it. blood is rushing to my eyes. my head. your heart is racing as fast as if it was -- as if you'd just run a marathon. how are you feeling, peter? i think i might need to throw up. the question is why do people do this to themselves? i'm going to find out after, how i feel. >> i believe it really works. the detox. >> reporter: a few hours later peter is feeling better. and as for me? >> still a little light-headed but also full of energy. almost back to normal. >> reporter: miracle medicine? maybe not. but the magic and wonder of the amazon, undeniable.

for "nightline" i'm mariana van zeller in peru. next, alec baldwin and lisa kudrow shared a fling on "friends." now they're reunited in the new animated movie "the boss baby." and later, gladiator russell crowe has the perfect response to people trying to body-shame him on social media. per roll more "doing chores for dad" per roll more "earning something you love" per roll bounty is more absorbent, so the roll can last 50% longer than the leading ordinary brand. so you get more "life" per roll. bounty, the quicker picker upper at red lobster's lobsterfestime. any of these 9 lobster dishes could be yours. so don't resist delicious new lobster mix and match

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♪ the last time alec baldwin and lisa kudrow shared a screen together, he played her annoying boyfriend on the hit sitcom "friends." now they're back together and he's playing an even more demanding and emotionally

draining man in her life. her baby. here's abc's nick watt. >> meet your new baby -- >> [ slow motion: "brother" ]. >> reporter: whoever thought to put the voice of alec baldwin with a baby with a briefcase is a genius. >> goo goo ga ga. >> you can't not have fun playing a baby in a suit with one of those diaper things. >> i guess your wife's doing all the diaper changing in your house. you don't even know the name of it. >> fine. i can talk. now let's see if you can listen. >> reporter: jimmy kimmel plays his dad. lisa kudrow plays his mum in the movie. >> is that really that strange, though, when you think about it? i would be the baby from the two of them i think. >> reporter: perhaps baldwin's most high-profile dig of late the president of course on "snl." >> siri. how do i kill isis? >> reporter: to acclaim from many but not the president.

"not funny. cast is terrible. always a complete hit job," he's tweeted. baldwin says he may not play the role much longer on "snl." unclear how much longer. but he is now clearing up with co-founder of spy, radio host, to write a book charting trump's first 100 days. >> kurt anderson and i are writing a book called "you can't spell america without me." thank you, by the way. thank you. a lot of pictures. kurt's going to do most of the writing because kurt's a great writer. >> what is your role? are you -- >> i'm trump. >> the two of you are writing it together? >> coffee table book pictures. >> oh, it's for fun. it's not a historical document, in other words. i mean, it's not like -- you're not -- i didn't understand. >> have you seen him on "snl" being president trump? >> i don't know what you're talking about. >> she knows. she's playing phoebe right there. baldwin and kudrow actually last worked together on "friends" circa 2002. >> i was her like really

annoying boyfriend. >> we probably should get going. >> ha, ha, ha, ha! classic ross. >> fire her. and don't make me ever talk to a woman that old again. >> reporter: and of course he was jack donaghy in the long-running highly acclaimed "30 rock."" >> jonathan, you're fired. >> why is your tie a little bit squint? >> i did 6 1/2 years of a tv show and that's all you have to say, is i messed up my tie? you turn to her and go your show is a great show. and your tie is a mess. >> i'm just surprised nobody ever -- >> can we start again? >> i'm surprised nobody ever told you that. >> for multiple reasons we need to start again. >> he was so good in "glengarry glen ross," perhaps he's never managed to escape it. >> coffee's for closers only. >> ripped off on posters for "the boss baby." by the way, he dressed his son as the boss baby for the premiere. >> you do get constant -- these kind of corporate monsters when in real life you seem like quite a nice chap. >> i think i am.

i've never played a movie part that was really what i am. what's going on inside of me. >> almost got to fix that. >> it's not about age. it's about intellectual heft. >> right. >> where did you go to college? >> vassar. >> she went to vassar. >> where did you go? >> i went to paconic community college. >> mm-hmm. >> that was so polite of you. there is no such thing as paconic. >> where did you go to college? >> st. andrews. >> they have a college at the golf course? what did you study? >> modern history. which is -- >> don't look at me that way. he's like, "modern history." i'll have you know. >> baldwin claims donaghy and boss baby share a soft core. >> inside those lines you see he's covering something. he's very needy. he does that to protect himself. he's completely full of you know what. >> who are you? >> let's just say i'm the boss. >> all right. back to "boss baby." he has a mission to get a cloned

puppy that babycorp. fears will steal all the love in the world. >> behold our mortal enemy. >> kids feel there's a finite amount of love. i was always asking my parents who do you love more? >> what did they say? >> we love you all equally. >> baldwin lives in new york city with wife hillaria and three young kids. the message of "the boss baby" is sibling peace is a good one. >> i have a 3-year-old, 1 1/2-year-old and a 5-month-old. in the end we have to hug each other and kiss each other and say they love each other. my wife is very smart that way. what kind of a dad are you? do you let it work out between them or do you intervene? >> i try to let them slug it out. >> you do. how scottish of you. my god. >> to a point. >> reporter: baldwin himself, don't forget, brother of billy and stephen. >> when i was a kid, my parents had six kids. boof. everybody breaking windows and shooting arrows into the wall. >> but did you send each other to the hospital ever? >> a couple times, yeah. >> so he's familiar with the

territory. this to me is about older brother who basically hates the new arrival. >> but you know, love conquers all, don't you think? >> yeah. i was choked up by the end of the movie. i was. i was. >> i believe you. >> reporter: sure. i mean, i was laughing. >> you don't mean -- >> reporter: i'm nick watt for "nightline" in los angeles. next, he's still got the heart of a gladiator. russell crowe coming back hard at his body shamers. wish your skin could bounce back like it used to? neutrogena® hydro boost water gel. instantly quenches skin to keep it supple and hydrated day after day. with hydrating hyaluronic acid, which retains up to a thousand times its weight in water. this refreshing water gel plumps skin cells with intense hydration and locks it in. for supple, hydrated skin

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and finally tonight, back in the day when i first saw that movie "gladiator," i never imagined it would come to this. >> my name is maximus decim decimus meridius. >> he stunned with his chiseled form in "gladiator." but now recent photos show russell crowe is sporting a different look. tabloids taking note today and page 6 tweeting "a moment of silence for russell crowe's hot bod." and a tweet saying howard stern

just goofed on your weight. crowe was quick to reply, tweeting back "i can bench press young howard. he cannot say the same." >> march. jack ely. don't get upset. i'm not here to hurt you. >> reporter: just last year the a-lister spoke out about gaining weight for the movie "the nice guys," saying "i wanted it to be the physical juxtaposition of ryan gosling." so with talk of a possible "gladiator" sequel what would our gladiator look like? director ridley scott weighing in saying "russell's changed a little bit." besides the need to resurrect maximus we still think crowe has that studly gladiator in him. thank you for watching abc news tonight. as always, we're online 24/7 at abcnews.com and on our "nightline" facebook page. thanks again for watching. and good night.