they have an abnormallal posture and they have muscular weakness. this description was so detailed and so excellent that physicians soon were able to characterize the disease and see exactly what parkinson's saw and they renamed the disease from shaking palsy to parkinson's disease. but it was a long time before we began to understand what some of the mechanisms underlying the disease was. it was only around 1960 we began to realize the disease is caused by the fact that there is a depth of dope minnick neuron, dopamine is a mad you la tore system in the brain that affects the striatum which is a key structure involved in motor coordination. we now know that a lot of the treatments that are available for it are based upon this initial deep insight. huntington's disease was discereddi0 years later,er about 1870. george huntington a columbia trained physician, very astute had the insight looking at families in long island that there were, it was a hereditary disease that he encountered which also affected motor movement. and the defining features of t