abramson has said about the way the drug companies disseminate information? satel: i know there are some problems. on the other hand, a lot of patients find this advertising very instructive. this is a hook that a patient can use to approach his physician who is not bound often just by the literature. they have their own experience with these drugs to draw on. abramson: most of our medical studies are now funded privately by the drug industry, and the odds are five times greater that the commercially- funded research will find that the sponsor's drug is the treatment of choice, than when the research is done on the same drugs - by non-commercial sponsors-- - satel: in psychiatry if someone comes in for depression, it's not as though i'm going to be mislead into prescribing the wrong drug. there are so many frontline drugs we can choose from. and then we often change along the way, and titrate and see how the patient responds. it's very empirical, and hands on, and-- caplan: john, before they resolve the evidence base for this poor little kid, i wanted to know

abramson: as a shareholder in hope, i'm gonna call for you to be fired. you're not fulfilling your responsibility. well, however the responsibility to the shareholders of hope are that five years from now we don't have a bunch of people walking around who are now saying, "oh my god, i suddenly have different structures in my head, and i'm seeing the world differently. you know, i'm going to hell in a handbasket here, and it's because i've been taking your drug." but gary, your answer again is predicated on the expectation that the drug is not safe. and i personally would expect that there will be safety issues that emerge. but the real question is: so what happens if in reality there is nothing wrong with this drug, except you can memorize a verse of shakespeare in one evening instead of a week? okay, the problem is and when you say, "it's been safe for 10 years." it's been safe for 10 years for people that have a major memory problem, all right? when you get into the area of cognitive enhancement, and you move from people that have frank disturbances to