[laughter] joining us now is alan krueger. he is the former u.s. mic advisers chairman. let's begin with you -- a weather report or jobs report? alan: i think it will be a weather report. hurricanes in the past have had an impact. jonathan: is there any aspect that we could find a little more reliable than the headline number? alan: i think labor force participation will be informative and may be more informative the most months even though it's somewhat noisy of a measure month-to-month. look at the people who said they had a job but couldn't work because of the weather. since that hurricanes were focused on texas and florida and georgia, it would be helpful if they could report to us like the rest of the country did. alix: so we get a number that is in line with what we are expecting. >> if we get a number that is gangbusters different and the likelihood that we will basically write it off due to hurricane is pretty high. alix: to the up and down side? >> to the up and down side. if the numbers are in the range of 100,000 give or take relative to

while all of this was happening, people lost jobs, became dependent on opioids, and alan krueger hasestimated that about 20% of the labor participatn workforce decline can be attributed to the opioid. we are having a workforce problem g test in order to get the jobs.it's become a catch 22e the solution is going to be a lot soledad: what do you do fore people who actually do have chronic pain and do consistently need painkillers, strong painkillers? aren't there nonaddictive medica work? buousome of those nonaddictive s may have consequences. what we need is research and development into drugs that will work on the same receptors in the brain to address pain but at the same time not beaddictive. there are lots of people who are figuring out nonpharmaceutical ways to address we must also woe cu pain in our nation, and that's anntsoledad: are you? the data would make somebody hopeless about what is going on in west vidr. gupta: i am alwayn optimi hn impact in the near term as well asrun. resources compared to what we have. a lot of communities are doing the best with what we have. soled

. >> reporter: a big deal for the broader economy as well, says princeton economist alan krueger. he's found a direct link between opioid use and out-of-the- workforce americans. >> for both prime-age men and prime-age women, the increase in prescriptions over the last 15 years can account for perhaps 20% of the drop in labor force participation that we've seen. >> reporter: the rate has been falling for years as the population ages, says krueger. but opioids are increasingly the story as the participation rate has hit historic lows. >> we've had a change in medical practices which has caused the medical profession to prescribe 3.5 times more opioid medication today than was the case 15 years ago. i think that's made it harder for some people to keep their jobs and has led them to leave the labor force. >> reporter: clyde mcclellan has seen it happening in east liverpool. >> when you drive around town, you see too many young and middle aged people just out during the middle of the day when normally they'd be at work. if they're out on the streets, many times they're not looking fo

you should note if you look at this neighbor -- labor participation rate overcapacity one years, alan krueger-2016 has a 2016an krueger study. there has been a 1/5 di declined for men and one fourth labore for women in participation. this has impacted families across the country. abigail: $500 million is being spent on the opioid crisis. some experts say it needs to be closer to $6 billion. is there any way that could happen, and what does that mean for tax reform? kevin: quite honestly, there will be a lot of pressure. next week will be focusing on silicon valley. i think the big pharma industry is facing intensified presser for the role in this. i would note carefully back when when we were reporting on the health-care debate, you had a five partisan -- a bipartisan group really pushing for an increased amount of funding to, this national crisis. at the issue of what we have seen in regards to national does that -- natural thisters, and now we have drug epidemic facing this country the president is signaling congress has to do something. if they are not, the federal government does have to

coming up, a great lineup of guests, including mohamed el-erian, alan krueger, rick rieder, and krishnanathan: it is the deadliest mass shooting in modern u.s. history. on the strip of las vegas, at least 50 people were killed, more than 400 were transported to area hospital, when a gunman perched in a high-rise hotel fired upon thousands at an outdoor music festival. the suspect identified as 64-year-old stephen paddock, who investigators say had more than 10 rifles with him in his hotel room. danya bacchus joins us with more. we are learning more about that shooter, 64-year-old stephen paddock. police saying they believe he was a lone shooter in this situation, that he had been staying at the mandalay bay since september 28. get when they were able to in the room, he had in excess of 10 rifles. we know now that they have entered his residence in another part of this state, but it will be sometime before we know what they find. they also believe he killed himself. abc news has been able to speak with his brother. he tells us the family is devastated. he says they do not know the reason