i am here with alex degrassi, a grammy award winning guitarist.e will continue with audience questions. >> you mentioned in your book, and right now, music has a pulse. i wonder what you think or know happens in the brain when music is disjointed, bad. how about classical music? >> one of the things -- whether you know it or not, whether you are a musician or not -- your brain is trying to predict what is or to come next, just like in speech. if i was going to say, the pizza was too hot to sleep, your brain is surprised because it had a prediction of what was going to come. a skillful physician will break it up harmonically, totally, or rhythmically, and when it becomes hard to predict, it becomes a game. what is your feeling about that? you do a lot of rhythmic changes. >> one of the things that i do a fair amount of -- maybe the question is asking, for example -- you have a piece of music, there is a rhythmic feel, maybe there is a break, a cadence, maybe it is played differently for a certain period. there is still a flow, as a musician, that y

into neuroscience and music with myself, daniel levinson, and the great guitarist and composer, alex degrassi. now, this meeting of in forum and the commonwealth club is adjourned. adjourned. [applause] impossible. announcer: when you open a book, you can explore new lands... [bird screeches] meet new friends, and discover new adventures. there are amazing possibilities when you open your mind to reading. [roar] you can log onto he library of congress website and let the journey begin. >> i'm your host of "culturewire," and today, here at electric works in san francisco. nice to see you today. thanks for inviting us in and showing us your amazing facility today. >> my pleasure. >> how long has electric works been around? >> electric works has been in san francisco since the beginning of 2007. we moved here from brisbane from our old innovation. we do printmaking, gallery shows, and we have a fabulous retail store where there are lots of fun things to find. >> we will look at all of that as we walk around. it is incredible to me how many different things you do. how is it you identify that san

into neuroscience and music with myself, daniel levinson, and the great guitarist and composer, alex degrassi. now, this meeting of in forum and the commonwealth club is adjourned. [applause] >> without much ado, let's move forward to the first order of the day will be a short opening ceremony. we're very honored to receive a welcoming address by san francisco mayor edwin lee, falling by opening remarks by ray lahood and ambassador, executive director of the apec secretariat. let us begin with a welcome from the mayor of san francisco. the city of san francisco is legendary. aides bay, its hills, its bridges, and its distinctive individuality. mayor lee took his position at the beginning of this year, appointed by the city board of supervisors to fulfil the unexpired term of the previous mayor. and he was tailor-made to lead this great city. as a former city administrator, he knows the city inside and out. he has spearheaded sufficiency measures, moved towards greater government services, prepared for emergency management in times of disaster, and work toward inclusion of all people in this m

into neuroscience and music with myself, daniel levinson, and the great guitarist and composer, alex degrassi. now, this meeting of in forum and the commonwealth club is adjourned. [applause]