how does the drug help, excited by it. -- alzheimer's - society. society. how does the drug help, how much does it alleviate the _ society. how does the drug help, how| much does it alleviate the symptoms? we're not choosing the word cure, but we are talking about is only early—stage alzheimer's disease, people of the very early stages, and with the trial showed cub and there is been very copperhead history with drug, and what it showed is that it will move this protein that builds up will move this protein that builds up in the brain and it will remove that very effectively, and then what the trial also suggested and with the trial also suggested and with the fda has said is there is good enough evidence to say it slow down cognitive decline, so did not hold it, it did not reverse it, slowed it down, and so there is enough evidence say it is doing that well enough the truck and go to this advanced accelerated approval rating, so they're saying they saw a slowdown in the tests before taking in the mental earth —— arithmetic test they were taking, so

the alzheimer's society... and there are many other treatments. eight years of underinvestment we are now seeing treatments getting through to regulators, into late stage trials. i think it really shows that research is and will beat dementia. you are clearly very excited by it. what of the late stage trials shown? what of the late stage trials shown? what does the drug... ? how does it alleviate the symptoms? taste what does the drug... ? how does it alleviate the symptoms?— alleviate the symptoms? we are definitely not _ alleviate the symptoms? we are definitely not using _ alleviate the symptoms? we are definitely not using the - alleviate the symptoms? we are definitely not using the word - alleviate the symptoms? we are j definitely not using the word you are. we are talking about early—stage alzheimer's disease. what the trial shows, it has been a complicated history with this drug, what it shows is that it remove this protein that built up in the brain and it remove that very effectively. andy trials also suggested by the fda said is that t

all the money raised by the bikini auction will go to the alzheimer's society.t the weather with chris fawkes. temperatures yesterday reached 28 celsius across south—east england, today will be hotter, 29 authority. with the air still humoured high temperatures to the south. to the north of that the air is fresher. the heat restricted to southern and eastern areas of england. temperatures of at least 29 celsius in london. compare that to fresher conditions for northern ireland, scotland, northern england, temperatures were typically 16, 18 celsius. most of us will keep you dry weather was sunny spell throughout the day but there will be some showers in scotland particularly for the highlands and islands but they will be fleeting. big gaps between the showers. 0vernight tonight patches of cloud. temperatures still slow to come down in the south—east. tuesday, scotland, england, wales, closure through the afternoon. of rain not far away. through the afternoon. of rain not faraway. fresherfeel to through the afternoon. of rain not far away. fresher feel to the weat

all the money raised by the bikini auction will go to the alzheimer's society.m bbc london. i'm tolu adeoye. today marks four years since the grenfell tower fire that killed 72 people. survivor nabil choucair lived on the 22nd floor and lost six members of his family. he's been telling bbc london he feels there hasn't been justice for those who died. in the last four years, i think my biggest problem is the fact that there has been no prosecution. you know, prosecution should have been a right. if anyone does anything wrong, you get taken into court and punished. why have these people still out there now not been punished? four years on, there are still londoners living in buildings with dangerous cladding. there are calls for the remediation work to be sped up. the government says billion of pounds has been set aside for it. we are making progress, great progress with the high—rises with the same cladding as grenfell. 95% of the buildings with that same cladding have been remediated, or works on site to carry out the remediation. with the final lifting of lockd

the proceeds will go to the alzheimer's society in memory of dame barbara, who died last year aged 83got there you got. i enjoyed it so much, i forgot you were not here. contactjon see if he remembers monday. good morning. carol was here. i was actually working for this programme for next week. so you say. what have you got? good morning. today, it is going to be hot. for some 10 degrees above average. sunny spells in the south—east but we have seen rain in northern ireland and scotland overnight and some of it has been heavy. there is a weather front moving south and ahead of it dry weather, sunshine to start the day, and mild where ever you are. the fog will lift in the south and you can see the rain in parts of northern ireland and southern scotland. north of that, showers knocking around. through the day, here comes the weather front. weakening all the time. the rain lighter in nature. showers in the north and west where it will be breezy. but humidity rising in the south as will the temperature with a high of 29, potentially 30. if we hit 30, it will make it the hottest day of th

all the money raised by the bikini auction will go to the alzheimer's society.be hotter than that. temperatures will reach 29. and an outside chance we might even sneak 30. with the air still humid, those high temperatures to the south of this line of cloud here, which is a cold front, and to the north of that, the air is fresher. the heat restricted to southern and eastern areas of england. temperatures at least 29c in london. compare that to fresher conditions for northern ireland, scotland, and northern england, where temperatures are typically 16—18c. most of us will keep dry weather with sunny spells throughout the day but there will be some showers in scotland, particularly for the highlands and islands, but they will be fleeting. big gaps between the showers. 0vernight tonight, we keep some patches of cloud in central areas of the uk. more comfortable for sleeping. temperatures still slow to come down in the south—east. it will be another warm start to the night. tuesday, a lot of sunshine to start the day, scotland, england and wales. northern ireland, n

the proceeds will go to the alzheimer's society in memory of dame barbara, who died last year aged 83her, with ben rich. for some of us, the weather is about to turn quite turbulent, especially towards the south and the east of the uk, where today we have had the best of the sunshine, and some pretty high temperatures as well to stop you can see in the earlier satellite picture, the storm clouds that have been drifting from up across france, and some are heading in our direction, particularly for southern, central and eastern parts of england, there is the risk for some thunderstorms tonight, and into tomorrow. torrential downpours in places. but in the shorter term, there is a lot of dry weather through the rest of the day, quite cool and fresh across scotland and northern ireland, a band of cloud bringing some rain for southern scotland, north—west england and west wales, but it is across central, eastern, southern parts of eglin where we have the highest temperatures. lots of sunshine, too. 29, 30 degrees, quite temperatures. lots of sunshine, too. 29,30 degrees, quite a humid feel

>> so the approval of the biogen is tremendous for patients and for society and everybody working on alzheimer'save been building for almost a decade now and allows us for the first time in history not only treat alzheimer's but also prevent the worsening. this is the first disease modifying drug. i think it's very important to say. there's a lot of room for improvement. in our case, we compare to the antibody infusions. that's where we come in, where we're trying to help. maria: i know this is a huge development for anyone or families dealing with their loved ones faced with alzheimer's many but we know there was a controversy at the fda over that approval of the biogen new drug, three advisory panel members resigned over the decision. what was the issue? your reaction to the pushback on approving that biogen drug. >> so the controversy was really about the data package, not whether the drug works. i'll get to that a little bit later. so the hurdle for approval, the threshold has been always two well controlled studies completed, that has a significant showing of efficacy. biogen discontinued b

alzheimer's but it doesn't come cheap at 56,000 bucks. it harkens back to stuff that you wrote about and i'm wondering, that is what we as a free society haveom this could be very beneficial, depending on their insurance company might never be able to enjoy it? >> well, it will be very beneficial for biogen. they will make billions of dollars on this, mostly from taxpayers through medicare. this is a drug that really has never been shown to work. it had some mri evidence of reduced plaque but no evidence of symptom changes. the one study never met its end points in terms of accruing samples. $56,000 a pop it, will be a heavy load for taxpayers and probably speaks to some of the larger problems we have in health care that i write about in the book. neil: you know one of the things that came up with coming up with a the vaccines to treat this they lost their patent protection or it was sacrificed in lieu of getting this out to everybody. what do you think of that approach in the rush to get something out companies give up some of the protections that normally they would be afforded in getting such miraculous cures out to people? >> well one o