rogers for all those years amino >> i want to introduce rebecca from silicon valley bank. rebecca >> i'm delighted to be here for the grand 0 opening pr i represent a lot of spflts. i want to give a shout out to faye who's our equity person and serving on the ac/dc board. we've provided over half a bloiltdz for the affordable housing in the bay area. we believe that economic inclusion is an important part of the diverse community. we do business by supporting affordable housing developers and after participating in the be financing of those fields. it takes a tremendous amount of teamwork and pool of resources to make this happen. i do want to highlight the city of san francisco's contribution to this deal. it wasn't the biggest dollars it was the first money in. once that money is committed to a deal it can be lifrjd to private and public sources. i comprehend the city for investing in our community through affordable housing and i hope they will continue their work. reverend fong and michael your respected team at urban core at ac/dc thank you for involving us it's a bea

to read you would probably get a kick of the fact that i have written about him because i feel like amino, some of my cousins are in the book. some of my friends. they get a kick and the fact that they are on the page and i am writing about them. exciting that he was heard about. >> to are some of the writers that influenced you the most in the same kind of the immaculate? >> let's see. john edgar walden. i think he wrote a book -- hero a book. a very important for me when i read it. two or three things. i love them one. brutal honesty. savannah was important, think, when i was writing. who else? but think that was important to me, specifically because his structure, it's not the usual, you know, accepted structure. added that it to see that done in in the memoir. it actually could pull it off. it was a lot of work. i was working on this one. and i love -- it's not a memoir, but i love james baldwin creating nonfiction this is. i love them. and read his essay about his mom's death, which i can remember the title of. i don't know. of course. tsa. is that what is? i love that as a. the way

similar in the sense that different proteins to have their own half-lives, determined largely by the amino acid. and yes, that some have a half-life of seconds, some minutes, some hours. and that very much determines their processing as part of how cells are regulated, something that the previous speaker was referring to as epigenetic phenomenon. so some proteins, if they are ready with her or hormones, they get degraded very fast and you remake them as they are needed. so the half-life of all the different proteins in your cells varies across the spectrum of all 20,000 somewhat proteins. >> great, thank you. your story of a single base pair change triggered a question on what you might think the limits of computational biology could be, which is when, if ever, do you think we would be able to computationally predict the statistical impact of a single base pay or change on the phenotype of? >> so, i think it's a great question. i devote not an insignificant part of the book talked about all the attempts to digitally model life, and most of the studies in fact a base on our sequencing of th

pee rna is a key molecule that actually brings in each amino acid one at a time for the synthesis of proteins. so these discoveries linked together to things, a huge step forward. the next decade actually brought the first stages of recombinant dna, start to make changes, and the key discovery, one of the key discoveries that enable this was one that my friend and colleague at the institute made, discovering the first restriction enzyme. these three gentlemen shared the nobel prize in 1978 for their discovery. but a number of people were able to take these new tools and use them for some pretty dramatic purposes. i described that not only did dna change in the 1970s, but so did dress codes. [laughter] so this was an early photo right after they made their first recombinant dna experiments work. and rapidly developing this to have a human insulin be produced out of a bacteria which was the basis of genentech getting going and the whole biotech industry taking off. genomics still advanced pretty slowly and it wasn't until 1976 that the first genome was sequenced, and it was a small rna

. >> elc amino del potro gutierrez , en los emiratos arabates comenzó con el pie izquierdo ante nigeriaes están instalados en la gran final del mundial pero quinees son estos guerreros. >> categoría suficiente encontramos a salomon díaz, y teran que pertenece al atlas todos ellos con 17 años , hernandez y ocho ason de chivas de guadalajara morelia y correa proeniente del américa , alejandro díaz es delantero del américa disputa dos goles. >> en el recorte muchísimas gracias, la gran final nigeria contra méxico se tiene que levantar temprano porque es a las siete y medía de la mañana por unimas y univisión deportes network mi pronóstico gana méxico dos uno . >> y mira que los nigerianos están agrandados , méxico es el mismo equipo que derrotamos es un jugador nigeriano con la confianza a tope. >> solo tiene 17 años. >> ahora evidentemete que ganarle a brasil como se le ganó te cambia, igual que argentina, italia , el equipo fue creciendo , por más que un rival sea el mismo los partidos son siempre diferentes, ellos tienen que t omar este partido como si fuese otro rival. >> estoy seguro

to contain with the protein of amino acids between tutus the 100th power of possible confirmation. so each protein has to try the combinations it would take 10 billion years for one of those principles discovered comedies process these happen with 1,000 of the second. so named lucky at paul and molecules' under the microscope with the ability to move around but it took about 75 years before einstein came along to actually show this movement that we see under any microscope so life is driven by the basic physical property of molecule's so we see that in the static for this but they constantly jiggle and gyrate in and rotate team and spin in people describe it as the of the equivalent of an earthquake going on constantly inside yourself so if you think of the process and the biological system with this shaking and movement so as long as it would never go back you don't have to peddle but to show one example of modeling that has been done of six microseconds here is in extended period of a small peptide and going from the olivier covered but when it happens in reality of six microseco

amino and we have a lot of african-american clergy and we're going to introduce now michael johnson with urban core. come on michael (clappin (clapping.)

amino and we have a lot of african-american clergy and we're going to introduce now michael johnson with urban core. come on michael (clappin (clapping.) i have a few prepared remarks you know the rooerdz are able to a.d. live but i've got to write my stuff down so i can be clear. so i want to thank you all for coming out today to celebrate the grand opening of the mary rogers senior center. i was home last time and before i went to bed i was trying to put together the words to say. i thought about it for the last several months. and i decided to frame it with a couple of points of history in my life. the first thing when i i was a teenager and attended a career day in philadelphia and learned with r what an architect does. i realized immediately that's what i wanted to do and went home and told mom and dad. my schooling prepared me for the education but the passion for redeveloping neighborhoods you such as the western edition was god-given. it's been fulfilling over the last thirty years. the second point of my personal history is when we were asked by the members of this community to

the only comet sampled with a return to earth and contain the molecule glicene that is an amino acid and one of the building blocks of life. it cannot only tell us about the early solar system and how our solar system formed, but possibly about the abundance of life and the universe. >> it is so close to the sun, anything about the sun itself? >> yes, it can. we noah lot about the sun as a star and the gravity is what dominates our sew darr sis -- solar system and makes our lives the way it does. we can always find out more about the sun as we see more objects encountering it. >> clearly you are watching this thing. what are you most excited about? what do you expect to see? >> i am excited because comets give you a rare opportunity to see things moving in the sky. most of the stars and the galaxies and things are so far off that the sky just looks like a status canvas and earth rotates, of course, and be see everything move. but to see something move through our solar system and dynamically change is very exciting. so unfortunately this is an early morning comet. you have to get up

you are born without a particular protein that turns an essential amino acid into another amino acid. you need this to live, but if it does not get transformed, too much of it builds up. for reasons we still don't understand, it kills brain cells. notids with pku that are up usually severely mentally retarded. we are not talking working at mcdonald's or special olympics. we are talking about kids who never learned to talk, go to the bathroom by themselves, close themselves.- clothe however, if we put them on a special diet within days of the test, there i queue stays with iq stays within the normal range. they may lose a few brain cells, but not many. so states require the test. only two states allow choice by parents not to do it. in every other state, it is a crime not to do it. a few states have philosophical or religious opt outs, although not many of them are used. typically, you may learn that it has been done, but typically, parents will not learn it or know about it because if it comes back as a negative result, your kid doesn't have it, there is no reason to tell you. if it i

acids --chain amino these are decent and i terry amino acids, and the place to get them, koran-fed beef-- cor n-fed beef. that might be a problem, as well. alcohol, a little bit is ok, and a lot is not. same with fructose. the reason that these for travel together is because they are essentially metabolized all the same way and differently from other calories. the liver is the only site for energy metabolism. everything goes to the liver. when your liver gets overloaded, it has to do with the excess. it is not insulin-regular kid. there is no way to die for the calories into another direction. and jim popoff. glycogen is liver starch. it is non-toxic. if you make glycogen, you're helping yourself. that is why marathoners cartload before a marathon race, to up their glycogen. the mitochondria of yourselves, the energy burning factors, are overwhelmed. straight to the mitochondria. they have no way to stop the onslaught. what the mitochondria do, they turn all the excess into liver fat, and liver fat drives chronic metabolic disease. what this proves is that a calorie is not a calorie. if

finlay: amino black reacts with the blood. rhodes: look at ridge detail.rprint in the first place. well, there was no context for it. the only useful evidence would have been to find claire gibson's blood on the handkerchief. otherwise, it's just ellis's blood on ellis's handkerchief in ellis's pants, so... wouldn't have been a big deal. (beeping) "yancey langer. restricted access." state employee? his name is on the major incident log. does this look familiar to you? looks like the handkerchiefs my mom always buys me for christmas. why? do you remember claire gibson's murder from march 21, 2006? sure. i remember everything. it was my first murder scene. i was a police explorer back then. your handkerchief was found inside gus ellis's pocket. he was the suspect at the time. can you explain that? yeah. i was waiting on a radio car to take him to the hospital to get a blood sample or something. guy was sitting on the curb, scared, got a nosebleed. he was dripping blood everywhere. i tried to stop it, then gave him my handkerchief. nosebleed. n-o-b-l. that wa

in to another amino acid. you need it to live. but if it doesn't get turned too much of it build up. and for reason that we still don't understand, 50 years after we have understood the basis of the disease, it kills brain cells. so kids with pku that are not treated end up severe mentally retarded. usually. we're not talking special olympics or working at mcdoddles. kids who never learn to talk. clothe themselves, et. if you put them on a special diet their brains are normal or close to normal. they may lose a few iq point but not very many. so they said every kid needs to be tested for pku at birth. over the last 35, 40 years. the number of diseases tested for has expanded. states require this two states only allow a regular choice by parents not to do it. a few states have philosophical or religious opt out. there have been a couple of interest and examples. typically you may learn it's been done. but typically parents won't even learn it or won't know because if it comes back as a negative result. negative this this case being

one for sequencing proteins and am amino acids, 22 years later -- this is an in-depth obit in the "washington they do their best work when they're younger. there's data on that. >> they said he was so modest -- >> you're 30 in some fields, you're done, to come back -- >> he worked ten years to sequence it and said he was so modest and unassuming thought he would be the caretaker of the lab he worked. i've got my eye on another guy winning another one. al gore. he's going to win another one. >> there's an interesting story about that, about people living and working longer is that they're keeping people younger from getting that first grant so they can do their best work in their 30s. exactly. people are not getting grants to do research at the prime of their intellectual lives right now. >> on that note. coming up -- what's going on? are we over? jour past th you're past that, right? >> i'm done, are you kidding me? >> mohammed el-erian will tell us why he thinks the fed is the market's best friend. plus, don't miss the season finale of american greed tonight. it's the fugitives. tonight's ep