ann thompson, nbc news, boston. >> tomorrow night we have a revealing interview. a drug company behind a new cholesterol drug explains why they are charging so much. >>> we're back in a moment with a big mystery tonight in one of the wealthiest places in america. >>> it is about to be a nightmare before thanksgiving for fans of pumpkin pie. crop experts say it will be plentiful for halloween but by the time thanksgiving rolls around it could be hard to come by because of the record rainfall in the midwest, including top pumpkin growing state illinois, washing out the crops. >>> off the coast of norway, a photographer captures this group of humpback whales swimming out of the green glow of the northern lights. it is a prime time to see the lights in that region. he spotted the whales while testing out a new camera. it looks like it works okay. >>> in southern california, who in ritzy bel air is using 1300 gallons of water per hour and why, at a time when homeowners are under tight water restrictions to combat the drought, one home is using nearly 12 million gallons

anne thompson, nbc news, new york. >> and there are a lot of questions about this. dr. roshini raj specializes in women's health and cancer treatment. doctor, thank you for being here. >> thank you. >> if a woman wants to get the mammogram at 40, ignore the recommendations and go with the others, what is the harm? >> there is not a big downside when you talk about getting it at 40. some groups are recommending it at 40. however, the new guidelines say 45 may be more reasonable because you are going to have some false-positives. that means people under 45 going to get the mammogram and they go through tests and anxiety and in the end it is not cancer. so they said start at age 45. but they did say, but if you want it at 40, you should have the opportunity to get it at 40. >> what should women do with this information today. >> the fact we have three different groups recommending three different times which means we don't know the exact time for every women. it is an individual choice. you need to discuss it with your doctor. this is for average risk women. if you have a

anne thompson, nbc news, new york. >>> that will do it for us on this friday night. i hope you join me later tonight for "dateline." a story we've been following for years about a notorious murder. a man convicted of taking part in the crime and for 25 years fighting for his freedom while proclaiming his innocence. that is dateline at 9:00, 8:00 central. i'm lester holt, for all of us at nbc news, thank you for watching and good night. ==janelle/vo== it's the strongest . >>> houses are putting boards on the windows. but they said that after 3:00, they -- >> it is the strongest storm ever to hit the western hemisphere. hurricane patricia made landfall just under two hours ago and it's pounding mexico right now. thanks for joining us. i'm janelle wang in forage mathai. >> i'm jessica aguirre. patricia is a monster category 5 storm packing winds as fast and furious as 200 miles an hour. millions of people are bracing for what could be catastrophic damage. want to give you a live look at puerto vallarta. 100 miles south of where the hurricane hit. >> puerto vallarta, one

anne thompson, nbc news, wayne, new jersey. >> we know the news will spur questions. let's bring in doctor roshiny raj. from the nyu medical center. doctor, a lot of viewers out there saying what am i supposed to do now. one option is stop eating meat and that is not likely. >> the occasional hot dog or salami is not going to make an impact. but we're talking about daily use increasing colorectal cancer which is the third leading cause of death in this country. so minimize your meats and occasionally is fine. but if you are doing it daily, it is time to change the habit. it is not the same category as cigarettes but it is shown to be a carcinogen based on 800 studies and thousands of people involved and they reviewed the evidence and made a stand here. >> doctor, thank you for being here. >> thank you. >>> a psychological evaluation has been ordered for the woman accused of plower her car into the oklahoma state homecoming parade this weekend, killing four people, including a two-year-old boy and a popular retired professor. eight people are still hospitalized and thr

ann thompson, nbc news new york. >> the extreme weather in western texas is a nasty-mofast storm. and within minutes the ground was blanketed in the wide. in arizona, heavy rains trapped a woman in her suv. meanwhile in arizona a funnel cloud was captured on video swirling in nearby morris town just west of phoenix. nbc meteorologist bill cairns is here with the wednesday hump day forecast. >> unfortunately more scenes like we saw yesterday. arizona and new mexico and now we're going to get texas into the mix here too. we still have showers and storms this morning in between albuquerque and el paso. and the couple of south o phoenix near tucson. the southwest severe weather risk about two and a half million people at risk of severe storms. damaging winds and hail are the biggest concerns out there. isolated tornado maybe at worst case scenario but the threat is low. texas and louisiana have been in a recent drought over the last couple of months. about 40% of the state of texas texas. this upper level low caused those storms. it is now droifting east and pulling moisture off the p

anne thompson, nbc news, new york. >>> we're back in a moment with what prince harry said changed his life while he and the first lady visited american veterans. >>> there are few people who lead more public lives than prince harry. we watched him grow up, suffer the loss of his mother, earn a reputation as a partyier and we watched him to go to war in afghanistan as a captain in the british army. that experience changed him and gave him a mission. today the mission brought him to washington to join special company. keir simmons was there. >> prince harry. [ cheering and applause ] >> reporter: prince harry has devoted himself to helping injured veterans. >> i'm in no doubt that the two deployments to afghanistan changed my life. there is little that can truly prepare you for the reality of war. >> reporter: like so many vets he left the war wondering what to do next. his answer, leave no one behind. today that mission brought him to ft. belvior, virginia, joined by michelle obama and dr. jill biden. >> wounded warriors aren't just a distance cause. to him they are brother and sisters

nbc's anne thompson lays it out for us. >> reporter: they have the sizzle so many people love. bason, sausage, the all american hot dog. today part of the processed meat labelled cancer causers by an agency of the world health organization. the same group said red meat, beef, lamb and pork are probably carcinogens. the risk, cole ore rectal cancer, underscoring what the american cancer society said it has been recommending for more than a decade. >> limiting the consumption is really important. because the risk increases with the amount of red meat and processed meat kmumed. >> processed meat is any meat, ham or bologna that is alter bid salting or curing. most have meat or pork but can contain poultry. it is said it causes cancer. about two slices of bacon increases the risk for colon cancer 18%. red meat which probably causes cancer, 100 grams aday, a piece the size of a deck of cards, raises the risk 17%. the report puts processed meats in the same category as cigarettes an asbestos but the danger is not even close. the cdc said smoking increases your cancer risk by 2,000%.

anne thompson, nbc news, new york. >>> we're back in a moment with what prince harry said changed his life while he and the first lady visited american veterans. another day, and i'm still struggling with my diabetes. i do my best to manage. but it's hard to keep up with it. your body and your diabetes change over time. your treatment plan may too. know your options. once-daily toujeo is a long-acting insulin from the makers of lantus . it releases slowly to provide consistent insulin levels for a full 24 hours. toujeo also provides proven full 24-hour blood sugar control and significant a1c reduction. toujeo is a long-acting, man-made insulin used to control high blood sugar in adults with diabetes. it contains 3 times as much insulin in 1 milliliter as standard insulin. p don't use toujeo to treat diabetic ketoacidosis, r during episodes of low blood sugar, t or if you're allergic to insulin. and may be life threatening. don't reuse needles or share insulin pens, even if the needle has been changed. the most common side effect is low blood sugar, which can be serious and life threat

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ann thompson, nbc news, boston. >> tomorrow night we have a revealing interview. drug company behind a new cholesterol drug will explains why they are charging so much. >>> we're back in a moment with a big mystery tonight in one of the wealthiest places in america. prosecute it and stop criminals our senior medicare patrol volunteers are teaching seniors across the country to stop, spot and report fraud you can help guard your medicare card don't give out your card number over the phone call to report any suspected fraud we're cracking down on medicare fraud let's make medicare stronger for all of us you...and itchy eyes.more than sneezing... they also bring tough nasal congestion. so you need claritin-d. it starts to work... ...in just 30 minutes. in fact, nothing works faster. so blow away nasal congestion, fast, with claritin-d. for adults with an advanced "squamous non-small cell", previously treated with platinum-based chemotherapy, it's not every day something this big comes along. a chance to live longer with... opdivo, nivolumab. opdivo is the first and o

anne thompson, nbc news, new york. >>> seven minutes past the hour. time now for some sports action. the leaders in the fall classic, they are just one game each from the world series. first now to the royals. the visiting team struck early and often against the hometown blue jays. in the end, k.c. beat toronto 14-2. a do or die game five is scheduled for 4:00 p.m. eastern today. wrigley field, the new york mets are on the verge of sweeping the cubs and heading back to the world series for the first time since 2000. red hot daniel murphy tied a major league record hitting five home runs in five consecutive postseason games. the mets could clinch tonight. game time is 8:00 p.m. >>> well, it's consumer reports' most anticipated and respected annual auto survey. tom costello now with how today's cars and suvs stack up, including some surprises. >> reporter: the list is compiled from 740,000 consumer reports subscribers, detailing how reliable their existing cars are. but new technology on the dash board and in the transmissions is proving to be a hang-up

as anne thompson explains it happened to one man this week ats w in aa. >> reporter: electronic vapor products marketed to help transition smokers from tobacco now pose their own growing danger. >> it exploded in his face. >> all right. >> electric cigarette. >> that is the 911 call his sister made after she said his e-cigarettes blew up on monday. >> my daughter said that there was a very large explosion in the home. she went toward the explosion to find him completely covered in black. >> the 21-year-old has been in a medically induced coma and on a ventilator with burns to face, chest and hands. injuries to other users and homes are raising alarms. the suspect, lithium ion batteries that power the batteries like the laptop batteries that are banned on airlines. here is how they work. the battery heats the liquid that contained nicotine to 350 degrees. creating a vapor the user inhales. the industry said the problem happens when consumers use the wrong battery charger. running the risk of overcharging the battery. that could lead to an explosion, and fire. >> be absolutely sure that

anne thompson, nbc news, new york. >>> that will do it for us on this friday night.hope you join me later tonight for dateline. a story we've been following for years about a notorious murder. a man convicted of taking part in the crime and for 25 years fighting for his freedom while proclaiming his innocence. that is dateline at 9:00, 8 central. i'm lester holt, for all of us at nbc news, thank you for watching and good night. and good night. vo: does hal parrish share our values? as mayor, parrish cut school funding nearly three million dollars. reading and science scores fell. parrish said no to opening new women's health clinics, denying access to cancer screenings and breast exams. so instead of dealing with the economy and jobs, parrish will join with the richmond extremists to slash education and threaten women's health care. hal parrish -- too extreme for virginia. feinblatt: everytown for gun safety action fund sponsored this ad. >>> lights, camera, access. >> how many more [ bleep ] pictures can you get? >> coast to coast and even overseas, the stars

ann thompson has more. >> it's the only nonsurgical form of birth control available. >> unlike gettingour tubes tied, the procedure is nonsurgical, and it's used by three quarters of a million women, and some of those women are now questioning the device' impact on their health. >> physically it has completely compromised my health in almost every aspect. >> over 14 years, it has led to a host of problems, severe headaches, leading to surgery, including a hysterectomy. she discovered a facebook page about it. >> at first i was relieved and then i was horrified all these women had the same group i did. >> that group has 25,000 members. >> so the device to avoid surgery may create the need for surgery? >> absolutely. >> implanting the the essure coils could lead to more complications than traditional surgery. >> we believe this is a reflection of a device failure and these procedures are done to correct the failure of the device. >> there are several assumptions that require clarification, and the doctor does not want the device banned but wants more women to have the information about t

nbc's anne thompson lays it out for us. >> reporter: they have the sizzle so many people love. bason, sausage, the

tonight anne thompson has a story of a promising treatment for cystic fieb brosis. we hear a lot about pharmaceutical drugs lately. >> they justify it by saying the cost of development and research is a lot. can that be justified? >> no one knows. it's a black hole as anne is going to report. companies are not required to explain how they set their prices and they do make the argument that research and development and those sorts of things and patients on the other end of these things wonder if there is price gauging going on. we'll take a deeper look at 6:30. >> all right. see you then. thanks a lot. >>> a memorial to victims of storm of protests in highlands. >> it went up overnight and it's free but some folks can't figure out what it is. new jersey reporter brian thompson joins us live from highlands with the latest. brian? >> reporter: and there's no question that this memorial is making waves here in highlands. you have to also throw in the factor that they have a town council election coming up in a few weeks and that really gives you an instant controversy.

anne thompson, nbc news, new york. >>> that will do it night. i hope you join me dateline. a story we've been following for years about a notorious murder. a man convicted of taking part in the crime and for 25 years fighting for his freedom while proclaiming his innocence. that is dateline at 9:00, 8 central. i'm lester holt, for all of us at nbc news, and good night.good evening, thanks for joining us. i'm matt breen. sheila has the night off. breaking weather news, tonight... tornado warnings have been issued for severa siouxland counties, tonight. for the latest, we turn to chief meteorologis t ron demers. weather ad-lib it was a day of rain and even some thunderstorms across siouxland as summer-like humidity suddenly returned to the area. this system will be moving out of here tonight and a cold front will cause winds to pick up as we could see gusts around 30 miles per hour during the night. we should quickly clear our skies on saturday and we'll stay dry right on through monday with highs in the

anne thompson reports. >> this is the image kay lan wants the world to see. but her cystic fibrosis means week long hospital stays to clear the 27-year-old's drugs. now a new drug offers hope and sticker shock. >> i think they put a price on any life. >> at a price tag of a quarter million dollars, she is begging her insurance company to pay for it but blames the drug maker. >> i think that it being priced so high isn't long-term justifiable. >> or camby and another drug treat the disease but neither is a cure. more. over $300,000 a year. >> are these break-through drugs? absolutely. >> reporter: this doctor has treated patients for almost three decades. patients who raise millions who help fund the drugs' development. >> i knew it would be an expensive drug. i thought it would be $100,000 a year, not $300,000 a year. >> for the rest of the patient's lives. tex. while developing a drug is a risky business and can cost more than a billion dollars,ver tex did not respond to our request to explain the prices. gouging? >> i have used the term profit earring. it i

nbc's anne thompson has a look at the numbers. >> reporter: the report says such meats cause cancer. eating 50 grams a day, about two slices of bacon, increases the risk for colon cancer 18%. red meat, which it says probably causes cancer, 100 grams a day, a piece the size of a deck of cards, raises the risk 17%. the report puts processed meats in the same category as cigarettes and asbestos. but the danger is not even close. the cdc says smoking increases risk your cancer by 2,000%. the $134 billion meat industry called the 800 studies the w.h.o. report looked at unconvincing. >> scientific evidence just simply doesn't support a causal link between any type of red or processed meat and any type of cancer. >> researchers said the risk of developing cancer from processed meat is small. about the magnitude of, quote, passive smoking. but they're adamant that the risk increase with consumption is significant. this morning, police in south carolina are investigating after a video surfaced that appears to show an officer dragging a high school student from her desk. a warning, and i'm ser

but first anne thompson with the new guide lines. >> reporter: in the season of pink -- the american cancer society moves the mammogram starting line. instead of age 40. today it recommends women start at age 45 if they are of average risk, without genetic mutations or a family history of breast cancer. at 55, women should transition to screening every other year if they have a life expectancy of ten years or longer. the american cancer society said the changes are designed to eliminate false positives and overtreatment. >> by 45, the benefits clearly outweigh the draw backs and all women should participate in screening. >> and no longer recommending clinical breast exams at any age. >> the life saving early detection is found in mammography. they can find a cancer before anybody with feel it. >> but there is disagreement on when to start. a federal task force said it should be age 50. the american college gynocology is sticking with 40. and one more obstacle for the mobile mammogram unit as they treat women in new york city. >> is this going to add to the confusion? >> without a dou

anne thompson, nbc news, new york. >>> that will do it for us on this friday night. i hope you join me later tonight for dateline. a story we've been following for years about a notorious murder. a man convicted of taking part in the crime and for 25 years fighting for his freedom while proclaiming his innocence. that is dateline at 9:00, 8 central. i'm lester holt, for all of us at nbc news, and good night. wow, that is good delicious with 46% fewer calories, 33% less sugar, and 50% more calcium than 2% milk it's great taste and better nutrition

anne thompson, nbc news, new york. >>> that will do it for us on this friday night. i hope you join me later tonight for dateline. a story we've been following for years about a notorious murder. a man convicted of taking part in the crime and for 25 years fighting for his freedom while proclaiming his innocence. that is dateline at 9:00, 8 central. i'm lester holt, for all of us at nbc news, thank you for watching and good night. my name is amanda and i smoked while i was pregnant. my baby was born two months early and weighed only three pounds. this is the view i had of her in the nicu. my tip to you is speak into the opening so your baby can hear you better. you can quit. talk

anne thompson, nbc news, new york. >>> that will do it for us on this friday night.hope you join me later tonight for dateline. a story we've been following for years about a notorious murder. a man convicted of taking part in the crime and for 25 years fighting for his freedom while proclaiming his innocence. that is dateline at 9:00, 8 central. i'm lester holt, for all of us at nbc news, thank you for watching and good night. . >>> oprah and ellen swapping their most personal confessions in two in two big tv tell alls. >> now on extra. >> oprah and ellen bare their souls to each other. breaking news about her weight and bank-busting new diet deal. >> in day she made $45 million. >> ellen on surviving her darkes >> would i still be famous? would they still love me? >> "keeping up with the kardashians." why khloe could be on the hook for lamar's escort bill. did a valet call kim fat? wait until you hear h