if tomorrow the us never authorised the astrazeneca oxford vaccine and shelved the johnson astrazenecashelved thejohnson & astrazeneca oxford vaccine and shelved the johnson & johnson vaccine, shelved thejohnson &johnson vaccine, it may shelved the johnson & johnson vaccine, it may not have that much impact on the us programme because they have other options, they have procured so much of the mrna vaccines and the particle vaccine may still be there. but the problem when you look at sub—saharan africa and latin america, they are all adenovirus vector vaccines, and if somebody signals a problem oran if somebody signals a problem or an alarm, that could have a devastating effect on the ability of africa and latin america to fight this pandemic. so it is so important how we operate and proceed, not only thinking about the safety of the american people but thinking about the world. us presidentjoe biden has urged russian president vladimir putin to ease tensions on the ukrainian border and suggested they hold their first summit. this comes as tensions rise over russia's military build—up n

if tomorrow the us never authorised the astrazeneca oxford vaccine and shelved the johnson astrazenecaved thejohnson & astrazeneca oxford vaccine and shelved the johnson & johnson vaccine, shelved thejohnson &johnson vaccine, it may shelved the johnson & johnson vaccine, it may not have that much impact on the us programme because there are other options, they have procured so much of the two mra vaccines in abundance. but the problem is that when you look at sub—saharan africa, latin america, they are all adenovirus vector vaccines. if somebody signals a problem or sounds the alarm, that could have a really devastating effect on the ability of africa and latin america to fight the pandemic. so it's so important how we operate and proceed, not only thinking about the safety of the american people but thinking about the world. professor, i know you know your subject through and through, but speaking in laypersons terms, if someone says they are worried about the vaccine, any vaccine, and worried about the risks of covid, what would you advise? h0 risks of covid, what would you advise? .

astrazeneca trial in children. ., oxford astrazeneca trial in children-— oxford astrazeneca trialhildren. you mentioned that by the time we get around _ children. you mentioned that by the time we get around to _ children. you mentioned that by the time we get around to vaccinating i time we get around to vaccinating younger age groups there may be other vaccines in play, anyway. and let's talk about moderna being rolled out in the uk for the first time today in wales. what do we know about this particular vaccine, its efficacy and how it fits into the wider vaccination programme? yeah, well, it's actually _ wider vaccination programme? yeah, well, it's actually very, _ wider vaccination programme? yeah, well, it's actually very, very - well, it's actually very, very similar to the pfizer vaccine. it's produced in roughly the same way and it works in exactly the same way as the pfizer vaccine. and when you look at the results of the phase three trials, it's very difficult, until you see the title on the top of the paper, to work out which data comes from witch trials, the results

first, what is the risk with oxford—astrazeneca? serious illness with covid is weighed against potential harms from blood clots. the official advice is for anyone who has had a firstjab and four days or more after that gets severe headaches, blurred vision or certain other symptoms, should contact a medical professional. a committee of europe's regulator, known as pr ac, to this conclusion. we know the benefits of the astrazeneca vaccine have been established. it prevents covid disease, it prevents hospitalisation and it prevents mortality. so in that respect prac feels that the overall benefits outweigh the risks. so will it delay the vaccine rollout? health officials say even with under 30s given a choice of alternative jabs, they're still course to offer all adults a first dose by the end ofjuly. so the road map should stay the same. although it does depend on supplies currently promised. of the vaccines currently in use, the government ordered 100 million doses of oxford—astrazeneca. though the rollout will slow down this month

you've been getting in touch with questions and concerns about blood clots and the oxford—astrazenecan i out in the uk, and the donor. we are expecting a busy afternoon on the i expecting a busy afternoon on the vaccine front. there is a news conference due from the ema at three o'clock this afternoon. we are expecting a separate news conference at some point from the mhra, that could be today or tomorrow. both groups have been looking into the possible link between the astrazeneca vaccine and a very rare blood clot, so we should get more information about that this information. —— this afternoon. important to point out, we're not talking about standard blood clots, it's very rare condition, normally found in the brain but sometimes of the parts of the body, that combine a blood clot with something called a low platelet count. platelets are the cells in your blood that are responsible for clotting. so it's very strange to see a low count of the road combined with clots in the blood. and that is what regulators, doctors have been looking into. the latest statistics, we should get an up

- oxford astrazeneca vaccine? yeah, this is a very _ oxford astrazeneca vaccine?a very challenging situation. because we do have an identified, very rare but serious adverse events. and i think what is happening now is good, that people are being informed, and communication has been happening right from the very beginning when a suspicion was a rose. so that's a good thing. in terms of what people should do about this, they should still have the vaccine but they need to be informed and they need to have a choice of whether to have it or not —— suspicion arose. there will be people who become more hesitant because of this particular risk, and they need to have an opportunity to have a discussion with a health professional and way of those risk carefully because there is a risk of not vaccinating as well. you specialise — not vaccinating as well. you specialise in _ not vaccinating as well. you specialise in vaccine - not vaccinating as well. you specialise in vaccine hesitancy. there's this idea of vaccine competence, potentially being dented. how do you counter th

so, if anybody is waiting to get their first vaccination, which may be the oxford astrazeneca or indeedcoming on stream all of the time, should i hold out for one of those? these are the questions that people will be asking. what is your advice to those people today, sir kent? well, i can only say that the relations of mine have been going to get their vaccinations and i have no concerns about them getting the astrazeneca vaccine. i'm far more concerned about them not getting a vaccine and catching the infection itself, which is a totally different risk profile to anything that might emerge from the latest analysis of the astrazeneca vaccine. he is the former chief executive of the mhra, and the briefing involving the mhra, and the briefing involving the mhra, and the briefing involving the mhra is due here at three o'clock this afternoon. that will be taking place at the same time as a briefing from the ema. it is going to give its assessment later on this afternoon of the astrazeneca vaccine. anna holligan has more from the ema's headquarters in amsterdam. so we are expecting updates

. >>> let's get to the developing story with the astrazeneca oxford university covid vaccine and questionslbaum is standing by in london with more on the developments good morning, juliana. >> reporter: dom, good morning yesterday was a big day for the astrazeneca oxford vaccine the uk and the eu medical rem regulators held press conferences where they delivered conclusions after the possible links with astrazeneca and a rare number of blood clots here is what they found. starting in europe, european medicine agency concluded there is a possible link between the vaccine and the very rare cases of blood clots 86 cases reported. 18 were fatal. out of 25 million people who received the vaccine because they were not able to identify or confirm risk factors, ema stopped short of restricting use of the vaccine it was slightly different in the uk let's tell you what we heard yesterday. similar messaging here the regulator said there is mounting evidence of a link between the vaccine and the cases of rare blood clots. they say the benefits continue to outweigh the risks for the vast majority of pe

and when stories began to emerge both in the uk and in europe, in particular about the astrazeneca, the oxfordstrazeneca vaccine and when they are reputable reports based on the safety data, the safety monitoring data we have a duty to report that. but also to set it into context. i really think the viewers and listeners and readers don't expect our reporting to simply be black and white. there are shades there. and it's about presenting the balance of the risk against the benefits. are you worried at all that some viewers feel that the bbc might be feeding vaccine hesitancy? well, i hope not. i can remember a couple of weeks ago it was on the six and ten o'clock news when the sort of, definitive or the latest raft of reports came out about the link between clots and between the vaccine. and the vaccine advisory group suggested that people under 30 here get an alternative jab. and it was important to present any risk within context. i knew that that's what was coming out. and that morning i contacted a professor at the wynton group in cambridge who is absolute world expert on communicating at

first, what is the risk with oxford—astrazeneca?e, as the potential for serious illness with covid is weighed against potential harms from blood clots. the official advice is that anyone who has had a firstjab and four days or more after that gets severe headaches, blurred vision or certain other symptoms, should contact a medical professional. a committee of europe's regulator, known as prac, drew this conclusion. we know the benefits of the astrazeneca vaccine have been established. it prevents covid disease, it prevents hospitalisation and it prevents mortality. so in that respect, prac feels that the overall benefits outweigh the risks. so will it delay the vaccine roll—out? health officials say even with under—30s given a choice of alternative jabs, they're still on course to offer all adults a first dose by the end ofjuly. so the road map should stay the same. although it does depend on supplies currently promised. of the vaccines currently in use, the government ordered 100 million doses from oxford—astrazeneca. though the ro

a flood _ for astrazeneca, for the oxford jab. a flood of— for astrazeneca, for the oxford jab. flood of british taxpayer money has gone into this. it comes is some slight _ has gone into this. it comes is some slight comfort that actually the government spent on this factory back at— government spent on this factory back at the beginning of the pandemic last year when we know that billions _ pandemic last year when we know that billions a _ pandemic last year when we know that billions a pound spent on ppe contract — billions a pound spent on ppe contract some of which came into nothing _ contract some of which came into nothing but this can be looked at as a strategic— nothing but this can be looked at as a strategic decision. reporting that the dutch— a strategic decision. reporting that the dutch were offered to come in at this investment and we are in this situation — this investment and we are in this situation where the british invested in the _ situation where the british invested in the dutch did not and that's only going _ in the dutch did not and that's only going to

first, what is the risk with oxford—astrazeneca?er you are, as the potential for serious illness with covid is weighed against possible harms from blood clots. some medication, including the contraceptive pill, also has a very small blood clot risk. anyone who has had a firstjab and four days or more after that gets severe headaches, blurred vision or certain other symptoms should contact a medical professional. a committee of europe's regulator, known as prac, drew this conclusion. we know the benefits of the astrazeneca vaccine have been established. it prevents covid disease, it prevents hospitalisation and it prevents mortality. so in that respect prac feels that the overall benefits outweigh the risks. so will it delay the vaccine roll—out? today a newjab was delivered for the first time in wales and scotland, made by the us company moderna. it is set to be offered elsewhere in the uk from next week. health officials say even with under 30s given a choice of alternative jabs, they're still on course to offer all adults a first

first, what is the risk with oxford—astrazeneca? lower the older you are, as the potential for serious illness with covid is weighed against possible harms from blood clots. some medication, including the contraceptive pill, also has a very small blood clot risk. anyone who has had a firstjab and four days or more after that gets severe headaches, blurred vision or certain other symptoms should contact a medical professional. a committee of europe's regulator, known as prac, drew this conclusion. we know the benefits of the astrazeneca vaccine have been established. it prevents covid disease, it prevents hospitalisation and it prevents mortality. so in that respect prac feels that the overall benefits outweigh the risks. so will it delay the vaccine rollout? today a newjab was delivered for the first time in wales and scotland, made by the us company moderna. it is set to be offered elsewhere in the uk from next week. health officials say even with under 30s given a choice of alternative jabs, they're still on course to offer all ad

the oxford—astrazeneca coronavirus vaccine trial on children and teenagers is temporarily paused tonight as the uk regulator investigates whether there is a possible link with rare blood clots in adults. oxford university say they won't carry out more jabs on younger people "out of an abundance of caution". more data is due to be published in the coming days — the world health organization says the vaccine�*s benefit largely outweighs the risk. forthe time being, there is no evidence that the benefit risk assessment for the vaccine needs to be changed. the argument continues over so—called covid passports — and what they might be needed for. the disappearance of 19 —year—old richard okorogheye — a body is about to be formally identified. fresh calls to deport members of a notorious rochdale grooming gang after one of the men was spotted in the town where he abused young girls more than a decade ago. also coming up... tributes to the actor paul ritter — best known for his role in �*friday night dinner�* — who's died of a brain tumour at the age of 5a. a trial of the oxford—astrazeneca cor

here in the uk, a trial of the oxford—astrazeneca vaccine on children has been paused while scientists blood clots in adults. the university of oxford has told the bbc that there are no safety concerns with the trial itself, but its scientists were waiting for further information. the prime minister borisjohnson has urged people to get their vaccination when invited. our medical editor fergus walsh reports. nearly 300 children aged 6—17 are taking part in the astrazeneca vaccine trial in england which began in february. oxford university said there had been no blood clots in the volunteers, but out of an abundance of caution, it had stopped vaccinations, pending the outcome of the safety review in adults. more than 18 million people in the uk have received the astrazeneca vaccine. the mhra said last week, there had been 30 rare cases of blood clots, including seven deaths. the prime minister, visiting an astrazeneca plant in macclesfield, once again gave his firm support for the vaccine. the best thing people should do is look at what the mhra say, our independent regulator, that's why

this and the oxford astrazeneca “ab? this is the and the oxford astrazeneca jab?e pfizer or madonna —— modern jab instead. we are still on track to offer the vaccine to all adults by the end ofjuly, but it does mean that we are taking this in the safest way possible to save as many lives as possible, as quickly as possible. that is the goal and i'm very grateful to these world class regulators who can spot this extremely rare events. i class regulators who can spot this extremely rare events.— class regulators who can spot this extremely rare events. i wonder if ou can extremely rare events. i wonder if you can take _ extremely rare events. i wonder if you can take us— extremely rare events. i wonder if you can take us through _ extremely rare events. i wonder if you can take us through some i extremely rare events. i wonder if you can take us through some of. extremely rare events. i wonder if i you can take us through some of the practicalities. you said those under 30 will be offered the opportunity to have an alternative vaccine. how will it work in practice?

thats because evidence is emerging of a link between the ox serve astrazeneca -- the oxford astrazenecand very rare blood clots. the u.k. regulator set up until the end of march, there had been 79 cases of rare clots with low platelets following a first dose of the astrazeneca vaccine. 19 people have died. that is out of 20 million who received the jab. that is one where clot -- one rare clot in every 250,000 vaccinations. >> these systems are detecting a possible side effect of the covid-19 vaccine, astrazeneca. in an extremely small number of people. the evidence is firming up. the balance of benefits and known risks of the vaccine is still very favorable for the vast majority of people. reporter: very few adults under 30 have died from covid, so that changes the risk-benefit balance from getting a vaccine. it's thought younger adults are at higher risk from clots after the astrazeneca jab. about one in every 100,000 doses. so they will be offered a different vaccine when there time c --ir times comes. are you worried this might damage vaccine confidence, especially in the young? >> t

_ confidently receive the oxford astrazeneca vaccine _ confidently receive the oxford astrazeneca vaccine second question i- astrazeneca vaccine if it is offered | to me. the second question i want astrazeneca vaccine if it is offered i to me. the second question i want to ask is— to me. the second question i want to ask is that _ to me. the second question i want to ask is that europe _ to me. the second question i want to ask is that europe remains— to me. the second question i want to ask is that europe remains one - to me. the second question i want to ask is that europe remains one of- ask is that europe remains one of the most — ask is that europe remains one of the most vaccine _ ask is that europe remains one of the most vaccine sceptical- ask is that europe remains one of. the most vaccine sceptical continent in the _ the most vaccine sceptical continent in the world — the most vaccine sceptical continent in the world. will— the most vaccine sceptical continent in the world. will allowing _ the most vaccine sceptical continent in the world. will allowing a - in the world. will al

i have had my first dose of the oxford astrazeneca vaccine and am 0xford astrazeneca vaccine and am lookingn't have the vaccine because you are worried about this, you are actually in a more at risk group. you are more likely to be dead at christmas than if you had the vaccine. so please do what the prime minister says and continue to go in for your second dose. i prime minister says and continue to go in for your second dose.- go in for your second dose. i think it's worth clarifying _ go in for your second dose. i think it's worth clarifying exactly - go in for your second dose. i think it's worth clarifying exactly what i it's worth clarifying exactly what you mean when you talk about younger people. you mean when you talk about younger --eole. . ., �* ~ ., you mean when you talk about younger ”eole. ., ., �* 4' ., ., people. yeah, we don't know for certain what _ people. yeah, we don't know for certain what the _ people. yeah, we don't know for certain what the age _ people. yeah, we don't know for certain what the age group - people. yeah, we don't know for certain what the age group i

astrazeneca vaccine. the link isn't proven but in future the under 30s will be offered a different vaccine. for nearly all age groups, the benefits of the oxforde in their 60s, with the current low level of virus circulation, for every 100,000 vaccinated, ia icu admissions would be prevented. at the same time, there would be a 0.2 or one in 500,000 risk of a rare serious plot. 500,000 risk of a rare serious clot. for people in their 20s, it's a finejudgment. there, less than one icu admission would be prevented but there would be just over one serious blood clot per 100,000 immunised. if we look at a period of high virus transmission, such as january, there, among the over 60s, 127 icu admissions would be prevented and nearly seven in the over 20s. neil aster began suffering headaches and nausea a week after having the astrazeneca vaccine. he died of a blood clot on the brain on easter sunday. his sister, a pharmacist, says he was extraordinarily unlucky. despite what has happened to neil and the impact on ourfamily, i still strongly believe that people should be going ahead and having the vaccine. if you have had one dose, go ahead and have y

here in the uk, a trial of the oxford—astrazeneca vaccine on children has been paused while scientistsossible link with rare blood clots in adults. the university of oxford has told the bbc that there are no safety concerns with the trial itself, but its scientists were waiting for further information. the prime minister boris johnson has urged people to get their vaccination when invited. our medical editor fergus walsh reports. nearly 300 children aged 6—17 are taking part in the astrazeneca vaccine trial in england which began in february. oxford university said there had been no blood clots in the volunteers, but out of an abundance of caution, it had stopped vaccinations, pending the outcome of the safety review in adults. more than 18 million people in the uk have received the astrazeneca vaccine. the mhra said last week there had been 30 rare cases of blood clots including seven deaths. the prime minister, visiting an astrazeneca plant in macclesfield, once again gave his firm support for the vaccine. the best thing people should do is look at what the mhra say, our independent

vaccine _ by providing the oxford—astrazeneca vaccine at _ by providing the oxford—astrazeneca vaccine on what we can provide and the material goods— what we can provide and the material goods we _ what we can provide and the material goods we can provide now like ventilators that we thankfully don't need any— ventilators that we thankfully don't need any more here and we are sending — need any more here and we are sending them overand need any more here and we are sending them over and the oxygen production machines which are being sent over— production machines which are being sent over from northern ireland, but also it— sent over from northern ireland, but also it is— sent over from northern ireland, but also it is the — sent over from northern ireland, but also it is the vaccine and the ability. _ also it is the vaccine and the ability, the deal that was done so that india — ability, the deal that was done so that india can produce its own vaccine — that india can produce its own vaccine based on british technology that is— vaccine based on british technology that is the — vaccine

i am in the position, i have had my first. position, i have had my first oxford—astrazeneca vaccine astrongly in favour of having the vaccine — strongly in favour of having the vaccine and i encourage everybody, like myself— vaccine and i encourage everybody, like myself and my family, to go for their second or indeed their first astrazeneca vaccine when called. were _ astrazeneca vaccine when called. were both — astrazeneca vaccine when called. were both referring to age. professor paul hunter, tell us about the significance of age. we are not currently vaccinating people not at risk, for example, below 50. it is risk, for example, below 50. it is very difficult _ risk, for example, below 50. it is very difficult because we have not seen _ very difficult because we have not seen reports of the case series, the number— seen reports of the case series, the number of— seen reports of the case series, the number of people who have had service — number of people who have had service venous sinus thrombosis definitively but we are certainly hearing — definitively but we are certainly heari

now, you will recall the astrazeneca/oxford vaccine was purchased by south africa and then abandoned it didn't work effectively against low and moderate cases of covid-19 in some trials because of the strain that is dominating here in south africa. so johnson & johnson vaccine is very important to south africa. they do hope that it will be temporary but the problem is already with some people jittery about vaccines any kind of question mark, even something like a really rare case that has been the case here in the u.s., will be an issue for rolling out the vaccine. haven't even started the vaccine rollout and there is this question mark, but they hope to clear it all up in a few days. >> let's hope that happens. david mckenzie joining us live from johannesburg, many thanks. >>> well, the u.s. intelligence community is warning of the devastating long-term impact of the coronavirus pandemic. this coming in its annual report that lays out the top security threats facing the u.s. cnn's alex marquardt takes a closer look. >> reporter: this is an annual report from the intelligence communi

the vaccine has been developed by the team behind the oxford—astrazeneca jab and the effectiveness isting. prof adrian hill of the university of oxford says he believes the vaccine has the potential to save tens of thousands of lives. this is very exciting. it's a very difficult disease to vaccinate against. it's caused by a parasite. we have no vaccines at all against any parasitic disease, so technically, this has been a long time coming. people have been trying to make malaria vaccines for many decades. so, this one really is part of a major collaboration between ourselves at the university of oxford, a fantastic manufacturer, 0xford, a fantastic manufacturer, the serum institute of india, the world's largest vaccine supplier to the world. and a biotech company in america. samy ahmar is head of health at the charity save the children. hello to you, thanks forjoining us. how revolutionary is this breakthrough, do you think? i think it's an incredibly _ breakthrough, do you think? i think it's an incredibly encouraging - it's an incredibly encouraging development. malaria is the seco

the headlines: the uk's medicines regulator, says the oxford astrazeneca vaccine is �*safe'.re blood clots. the european medicines agency says blood clots should be listed as a very rare side effect. the british government says it will provide targeted help to the hundreds of thousands of hong kong citizens expected to move to the uk using a special visa. the chinese government has introduced a security law there which restricts longstanding democratic freedoms. at the murder trial of the former police officer, derek chauvin — the prosecution has reversed part of its evidence over the words uttered by george floyd. after initially accepting mr floyd had said "i ate too many drugs" — they now believe he actually said "i ain't done no drugs. now on bbc news, it's hardtalk with stephen sackur.

that's because evidence is emerging of a link between the oxford—astrazeneca vaccine and very rare bloode uk regulator, the mhra, said up to the end of march, there have been 79 cases of rare clots with low platelets following a first dose of the astrazeneca vaccine. 19 people have died. that's out of 20 million who received the jab. that's one rare clot in every 250,000 vaccinations. these monitoring systems are now detecting a potential side effect of the covid—19 vaccine astrazeneca in an extremely small number of people. the evidence is firming up. the balance of benefits and known risks of the vaccine is still very favourable for the vast majority of people. very few adults under 30 have died from covid, so that changes the risk—benefit balance from getting a vaccine. it's thought younger adults are at higher risk from clots after the astrazeneca jab, about one in every 100,000 doses. so they will be offered a different vaccine when their time comes. are you worried that this change of course might damage vaccine confidence, especially in the young? these are really carefully consid

papers, the guardian leads with today's news that under—30s in the uk won't be offered the oxford astrazeneca concerns over the risk of rare blood clots. the financial times says the "abrupt shift in guidance" could complicate the country's vaccination programme, and that downing street have played down the significance of the announcement. "keep calm and carry onjabbing" — the daily mail says politicians and scientists are urging the public to keep faith in the vaccine. and the i claims that according to scientists, the uk can still deliver a jab to every adult by the end ofjuly. the telegraph has spoken to the family of a man who died from a blood clot on the brain after taking the astrazeneca vaccine. his sister says he was "extraordinarily unlucky" and is urging people to continue taking the vaccine to "help save lives". in other news, "britain getting back on track at last" — the metro reports that there will be 18,000 train services a day from next monday as the country begins to come out of lockdown. a lot to get through, and as always, thank you very much, both of you, for being with

the oxford—astrazeneca coronavirus vaccine trial on children and teenagers has been paused while thek regulator investigates whether there's a possible link with rare blood clots in adults. experts say there are no safety concerns. the us has hailed the start of talks in vienna which aim to revive the iran nuclear deal as a welcome and constructive step. the two sides are not meeting directly, but talking hello and welcome to our look ahead to what the the papers will be bringing us tomorrow. with me are rosamund urwin, senior reporter of the sunday times and broadcaster and author, john kampfner. tomorrow's front pages. starting with. the cost of coming home from a foreign holiday could be up to £420 per person, reports metro, as a result of needing to pay for covid tests, with a warning from easyjet that summer breaks could be for the wealthy only. but the daily mail says affordable holidays could be on the horizon within weeks, as it reports that the prime minister has asked officials to look into using quick and cheap lateral flow tests, rather than costly pcr tests for traveller

the headlines: the uk's medicines regulator says the oxford astrazeneca vaccine is safe.the european medicines agency has said any blood clots should be listed as a very rare side effect. myanmar�*s ambassador to the uk says his embassy in london has been taken over by the burmes military and he's been locked out. kyaw zwarminn, who opposed february's military takeover in myanmar, says he's been the victim of a kind of coup in the middle of london. indirect talks between washington and tehran have continued in vienna. the state department has said america is prepared to remove sanctions on iran, in order to resume compliance with the 2015 iran nuclear deal. president trump pulled the us out of the agreement in 2018. ever since the first reports suggesting a link between blood clots and the astrazeneca vaccine, there have been

that's because evidence is emerging of a link between the oxford—astrazeneca vaccine and very rare bloode uk regulator, the mhra, said up to the end of march, there have been 79 cases of rare clots with low platelets following a first dose of the astrazeneca vaccine. 19 people have died. that's out of 20 million who received the jab. that's one rare clot in every 250,000 vaccinations. these monitoring systems are now detecting a potential side effect of the covid—19 vaccine astrazeneca in an extremely small number of people. the evidence is firming up. the balance of benefits and known risks of the vaccine is still very favourable for the vast majority of people. very few adults under 30 have died from covid, so that changes the risk—benefit balance from getting a vaccine. it's thought younger adults are at higher risk from clots after the astrazeneca jab, about one in every 100,000 doses. so they will be offered a different vaccine when their time comes. are you worried that this change of course might damage vaccine confidence, especially in the young? these are really carefully consid

you remember the astrazeneca/oxford vaccine was abandoned because it didn't work against mild and moderatecause of that dominant variant here in south africa. so the j&j vaccine also a one-shot vaccine that is easy to store is a key part of the strategy here. now, it must be said that the regulators here say they believe this will be a temporary stop, a pause, they're taking the cue of the fda and hoping that it will be unpaused in the coming base of the of the 290,000 odd health care workers that we witnessed getting the vaccine as part of a large-scale trial, this he haven't had a single case at this stage of that rare blood clot that has been reported in the u.s., but really there is a worry that vaccine hesitancy could become an issue. they abandoned one vaccine, now there is a question mark over another one, even though people are trying to allay fears and in the coming weeks 30 million johnson & johnson vaccines will be rolling out in south africa. they are hoping that those vaccines will be into arms very soon and that this pause doesn't drag out. christine, laura. >> and they impor

astrazeneca vaccine. the link isn't proven but in future the under 30s will be offered a different vaccine. for nearly all age groups, the benefits of the oxford, with the current low level of virus circulation, for every 100,000 vaccinated, 1a icu admissions would be prevented. at the same time, there would be a 0.2 or one in 500,000 risk of a rare serious plot. for people in their 20s, it's a fine judgment. there, less than one icu admission would be prevented but there would be just over one serious blood clot per 100,000 immunised. if we look at a period of high virus transmission, such as january, there, among the over 60s, 127 icu admissions would be prevented and nearly seven in the over 20s. neela stills began suffering headaches and nausea a week after having the astrazeneca vaccine. he died of a blood clot on the brain on easter sunday. his sister, a pharmacist, says he was extraordinarily unlucky. despite what has happened to neil and the impact on ourfamily, i still strongly believe that people should be going ahead and having the vaccine. if you have had one dose, go ahead and have your second. if you haven't had a dose yet, make

astrazeneca vaccine. the link isn't proven, but in future the under 30s will be offered a different vaccine. for nearly all age groups, the benefits of the oxfordor people in their 60s, with the current low level of virus circulation, for every 100,000 vaccinated, ia icu admissions would be prevented. at the same time, there would be a 0.2 or one in 500,000 risk of a rare serious plot. 500,000 risk of a rare serious clot. for people in their 20s, it's a finerjudgment. there, less than one icu admission would be prevented, but there would be just over one serious blood clot per 100,000 immunised. but if we look at a period of high virus transmission, such as january, there, among the over 60s, 127 icu admissions would be prevented and nearly seven in the over 20s. neil began suffering headaches and nausea a week after having the astrazeneca vaccine. he died of a blood clot on the brain on easter sunday. his sister, a pharmacist, says he was extraordinarily unlucky. despite what has happened to neil and the impact on ourfamily, i still strongly believe that people should be going ahead and having the vaccine. if you have had one dose, go ahead an

. >>> the oxford/astrazeneca vaccine is facing yet another setback.he university is pausing its pediatric trial in the uk as regulators review a possible, i say possible link to blood clots in adults who have been inoculated. a spokesperson says no safety concerns have been raised regarding the children's trial. european regulators are once again reviewing the vaccine and are expected to release their findings sometime this week. for more on all the latest developments melissa bell is standing by for us in paris. first we go to salma abdelaziz in london. a lot on the line for astrazeneca but also for the uk and other european countries. this is their best shot to try to get over this pandemic. what's at stake here as we wait for more information on astrazeneca? >> reporter: paula, i'm going to expand that a little bit. it's not just about the uk and the eu, there is a lot of excitement around the oxford university and astrazeneca vaccine when it first came out because it only costs about $4, it is cheaper than your cup of coffee and it doesn't need to

the uk medicines watchdog say the benefits of the oxford astrazeneca vaccine continue to outweigh anyfor the vast majority of people. but due to a very small number of blood clots in younger people, those under the age of 30 will be offered the pfizer or moderna vaccine instead. a review carried out by the mhra found that by the end of march, of the 20 million people who have received the astrazeneca jab, 79 people in the uk suffered rare blood clots after vaccination, 19 of whom died. the regulator said this was not proof the jab had caused the clots, but that the link was getting firmer. and the prime minister said he had not seen anything that would cause the uk to deviate from its road map for relaxing covid restrictions in the coming weeks. speaking in the last hour, the chief executive of the mhra june raine gave more details about those who had been affected by the rare blood clots. based on the current evidence, the benefits of the covid—19 vaccine astrazeneca against covid—19 and its associated risks, hospitalisation and death, continues to outweigh the risks for the vast maj

. >>> health authorities in the united kingdom are urging the public not to avoid the oxford/astrazenecaaccine. they say all three of britain's approved vaccines are safe. that's after british officials confirmed the potential but rare link to blood clots. salma abdelaziz explains. >> reporter: british health officials are now rushing to reassure the public after it was confirmed that there is a potential link between very rare cases of blood clotting and the oxford university and astrazeneca vaccine. the uk health secretary saying this shows that the regulatory bodies, the checks and balances behind the vaccine, are working because they were able to detect very rare incidences, four out of a million. that is the likelihood of these very rare cases of blood clots occurring. however, it is of course causing confusion, concern and global repercussions with several countries taking steps to limit the use of this vaccine in certain age groups. australia say they are now going to have to recalibrate their vaccine rollout to give this vaccine to only those over 50 years old. italy as well now

march, more than a dozen countries, including france and germany, suspended their use of the oxford astrazeneca shop over the blood clot issue. but most eu nations restarted its use in mid-march after the ema said the benefits outweigh the risks. u.k. prime minister boris johnson addressed the issue at an astrazeneca manufacturing facility on tuesday. >> the best thing people could do is look at what the advice is to people, to keep going out and getting your jab, your second jab. >> but it is one of many agencies still investigating the blood clot concerns. in the u.s., the fda has not given the green light pending its own study in the world health organization and is investigating thblood clot concerns. if confirmed, the chances appear to be low, with a german study finding 31 cases of blood clots and nine deaths out of two point 7 million people vaccinated. the ema is expected to make an official statement sometime this week. >> that is the latest on the astrazeneca vaccine. let's bring you the latest on covid-19 across france. the figure is up 913, a total of 5626 people in intensive care d

a trial of the oxford—astrazeneca vaccine on children has been partly suspended while scientists investigatesible link with rare blood clots in adults. the university of oxford has told the bbc that there are no safety concerns with the trial itself but that scientists were waiting for further information. the medicines regulator, the mhra, is reviewing rare cases of thrombosis that have been reported in adults who've been vaccinated. parents and children are being told to continue to attend all scheduled visits and the prime minister borisjohnson has urged people to get their vaccination, when invited, to reduce the risk of a third wave of infections, as our medical editor fergus walsh reports. nearly 300 children aged 6—17 are taking part in the astrazeneca vaccine trial in england which began in february. oxford university said there had been no blood clots in the volunteers but out of an abundance of caution it had stopped vaccinations, pending the outcome of the safety review in adults. more than 18 million people in the uk have received the astrazeneca vaccine. the mhra said last week

will there be new advice regarding the oxford—astrazeneca vaccine?s medicines regulator and the european medicines agency are currently investigating a possible link with rare blood clots in younger adults. they are due to updated advice later today or on thursday. in the uk, trial of the vaccine on children in the uk has temporarily been halted. the university of oxford has told the bbc that there are no safety concerns with the trial itself. 0ur medical editor, fergus walsh, reports. nearly 300 children, aged 6—17 are taking part in the astrazeneca vaccine trial in england which began in february. 0xford england which began in february. oxford university said there had been no blood clots and volunteers but out of an abundance of caution it had stopped vaccinations pending the outcome of the safety review in adults. more than 18 million people in the uk have received the astrazeneca vaccine. the mhra said last week the happy 30 rare cases of blood clots including seven deaths. —— there had been 30 rare cases. the prime minister, visiting an astraze

remember we have now got three vaccines, oxford astrazeneca, pfizer. vaccines, oxford astrazeneca, pfizerore transmission in the community, and of course with these new variant strange such as the south african strains, we don't want that to become prevalent in this country because the vaccines don't work quite as well. so i think he is trying to be cautious for everybody. we all want to get our lives back and enjoy ourselves again, but we must be cautious and do this slowly, otherwise we will go back to square one. 50 otherwise we will go back to square one. , .,, ., . otherwise we will go back to square one. , ., . ., otherwise we will go back to square one. ., . ., ., ., one. so people who want to go to the ub, sit one. so people who want to go to the pub. sit outside _ one. so people who want to go to the pub, sit outside a _ one. so people who want to go to the pub, sit outside a cafe, _ one. so people who want to go to the pub, sit outside a cafe, go _ one. so people who want to go to the pub, sit outside a cafe, go for- one. so people who want to go to the pub, sit outside a cafe,

a trial of the oxford—astrazeneca vaccine on children is suspended in the uk, while the country's regulatorof china's parents are limiting themselves to a single child, despite now being allowed to have more. translation: for me, - it's already hard to raise this one.

the uk's medicines watchdog has made a change to its advice on the use of the oxford astrazeneca vaccinee. it stressed that the benefits of the vaccine continue to heavily outweigh any risks for the vast majority of people. but because some rare blood clots have been found in extremely small numbers of people who have received the astrazeneca jab, those under the age of 30 will be offered an alternative vaccine instead where possible. earlier, the chief executive of the and hr eight, june rein, gave more details about those who had been affected. 0ur who had been affected. our review is that the risk of this side effect remains extremely small. by side effect remains extremely small. by the 31st of march, over 20 million doses having been given, we have had 79 case reports up to and including that date, the 31st of march. all 79 cases occurred after the first dose. of these 79 cases, 19 people have sadly died. these cases occurred in 51 women and 28 men aged 18 to 79 years. from these reports, the risk of this type of rare blood clot is about 4 million —— about four people in a million w

medicines regulators have concluded there is a possible link between the oxford astrazeneca vaccine and where blood clots. they insist the risk of the coronavirus is greater than the risk of death from clotting. the number of virus deaths in brazil has dipped slightly from a record high of 4200 announced on tuesday. another 3800 deaths were reported on wednesday with 92,000 new infections. as he has throughout the pandemic, president bolsonaro continues to play down covid-19. an expert and a the use of force has testified at the trial of the police officer accused of killing george floyd. she said derek chauvin used inappropriate deadly force. >> do you have an opinion to a degree of reasonable uncertainty for how much force was reasonable to use on mr. floyd was handcuffed and not resisting echo >> yes. >> what is that opinion? >> my opinion is no force should have been used once he was in that position. >> the u.s. has agreed to withdraw all the remaining combat forces deployed to fight against isil. talks with the iraqi government did not settle on a timeline. some soldiers and coali

. >> john: this vaccine in the astrazeneca oxford one uses a similar vector, an adenovirus to deliver the information that your immune system needs to rev up. as you pointed out it is different than moderna advisor. question for you. even as johnson & johnson says that there is no causative effect, there's a lot of people, including one about 10 feet away from me who got this j&j vaccine in recent days. the window of danger appears to be six to 13 days. what should people who just received that vaccine be watching for? what could they potentially do to mitigate the chances of them developing this rare occurrence? >> believe it or not the first thing i would tell people is keep in mind that 11% of people who have covid-19 get serious blood clots that are life-threatening. i am trying to cut through the fear messaging. you're one of the million chance, even if you got this vaccine come of having a problem, it is less than one in the millions of course you should be on the lookout for headaches. of course you should be on the lookout for dizziness or any kind of difficulty like that. tha

because a similar vaccine from astrazeneca, oxford university in europe saw similar blood clots. >>>ave is what action if any will the fda take? >>> we know the name of the officer who shot wright. kim potter, 26-year veteran of the department. the police chief said she meant to grab her taser but instead grabbed her gun. >>> yesterday they focussed on appealing to the emotions and put george floyd's younger brother on the stand. >>> a new vaccination tour toured for members of the theater industry. >> we want to gather again, and we want to tell stories in the dark. we cannot do that if we don't feel and if you don't feel safe. ♪ >>> despite what you're hearing, all the experts say still get the vaccine. it is disconcerting at this time. >> it is. >> for some people. >> and that's where we're going to begin with the breaking news at federal health officials say the j&j covid vaccine should not be used for now after six recipients got blood clots and one died. the cdc and fda say all the patients were women between the ages of 18 to 48 who developed that dangerous condition within a

a trial of the oxford—astrazeneca covid vaccine on children has stopped giving outjabs while the uk'sor investigates a possible link with rare blood clots in adults. the university of oxford has told the bbc that there are no safety concerns with the trial itself, but its scientists were waiting for further information. 0ur medical editor, fergus walsh, says the decision has been taken out of an abundance of caution. there are no safety concerns in the volunteers, they simply thought it would be sensible to stop vaccinating while this adult review was going on. now, no medicine, whether it's paracetamol or vaccines, is risk—free, but unpicking whether there is a link between the astrazeneca jab and these incredibly rare blood clots is frankly difficult. and the incidents in the uk is thought to be one case in every 600,000 vaccinations, in germany, it's higher, nearly all there involving younger women. and each case has to be investigated. did those involved have underlying conditions, did they have covid, which increases your risk of clots, and is there a connection between them? we