we have joining us, mitchell warren, who runs a vac, now, avac, i am on the board. a big conflict of interest there. mitchell will talk about some of the perspectives where the research is from the organization, focused on hiv prevention. and margie runs the hiv initiative. product development partnerships, focused on bringing together a multiple sets of actors to it will be a great opportunity to hear from her, where the partners are, and the leading pdp in this area. for format, about 30 minutes for dr. fauchi, to give a presentation, and then, we move to mitchell warren, eight or ten minutes of comments, margie mcglenn, and then, open it up for the panel for you to engage them in questions and answers, i will moderate that. that is a good chance for you to see where we are with hiv research, dr. fauchi, over to you. thank you for coming. it is a pleasure to be here with you today. i am going to talk a bit about the issue of the role of an hiv vaccine. i want to start off by putting into perspective the concept of why we really do need an hiv hax vine, despite the