now, often this comes with a sticker shock, for example, avastin, 88,000 there$88,000 a s medication.rs, very expensive, and this is 124,000 for four doses, big sticker shock, not taking into account the hundreds of thousands, and for what the physician charges, all of it goes into the cost. and it adds up quick. as part of the clinical trial, brian got the drug free, but could only continue because the company that makes the drug agreed to keep providing it. >> i think with the drug, i could see the scans and that the disease was going away. and i knew that good things were happening. you kind of get a taste of what that was like before cancer. >> and what it takes. a year after his diagnosis, brian and lupe got married. in some people, the drug works miracles, the problem is, they don't last. >> i've had patients that have been bedridden that could take their kids to disney world. so it has had dramatic responses. the issue is, they object last a few months -- only last a few months, then the tumor comes back. >> reporter: and this time, he told him it was time to try something else