that - you can get undercooked meat from it, well, this is somehow not good at all, this was the baden badenost konstantin severinov, today we talked with academician of the russian academy of sciences vitaly vasilyevich zverev about seasonal infections, viruses, about the world health organization, let's get started, oh, i'm playing, hello, hello, welcome, oramalests. welcome to semenov, hello, nizhny novgorod region, we missed you! and the plane was flying, the propellers were spinning, and you were waiting for us here, and we showed up, and we showed up, and all beautiful, and we are vsemenov, we will be happy , and what, what, friends, dear, is the city of semenov famous for? well, first of all, because since the 17th century this place has been famous for the famous folk craft, khaklov, well, there is no person who would not know, here you go, in the hands of the guys, so once kaklom spoons, and you do not play with us, here guys, now for now, now the guys will do it. let's quit! and we are cheerful guys, and we will not disappear anywhere, we'll play the accordion, we'll sing songs, we

this is the baden baden podcast, i am its host konstantin severinov, and today we are discussing vaccinationou have 30, well, let's assume that there are 30, well , let's say, 30 pathogens that are. well representatives of some large group of related viruses, not related, well no, each of them is, a representative, and you for each, and you for each of these, for each of these groups you more or less understand what needs to be done, just as in the case of coronaviruses, one of which was sar-2, in this sense you are ready for most known viruses of course you are ready yes, but not for all, moreover, when you... say good words to the government or the president, you just need to give credit, they played a key role, without them, well, how could it have been to implement such an amazing, that is, you and are you a hero of russia or not, no, no, well, still a hero, because when i thought about this, well, so detachedly, after all, as a country we are lagging behind quite a lot, well, in the field of biomedical research, some part of it, yes, we are lagging behind, of course, but at the same tim

baden baden podcast and i am its host konstantin severinov. today we will talk about antibiotics and we will talk with sergei vasilyevich tsarenko, the chief resuscitator. these are prokaryotes, bacteria, antibiotics are against them, although in general there are antibiotics and antitumor agents, but mainly against bacteria, who produces them, these are chemists made, where do these substances come from, well, to begin with, actually, they were found in nature, this is a way for bacteria to coexist with each other, some bacteria produce antibiotics to drive other bacteria out of their habitats, a fight for food, for a place to live, and so on, and what do medicines have to do with it, we also have microbes on us, inside us, and we also have antibiotics inside us, well , our bacteria also produce them, but actually, the most powerful antibiotics, of course, our bacteria do not produce, which live in us, basically they are antibiotics produced by bacteria living in the soil, accordingly they are found there, after that there are two options for them... and these are some kind of factories , microbiological industry or chemical factory, which makes a substance, this is some kind of molecule, but this is a molecule, yes, you are a resuscitator, you encounter antibiotics in your medical work, this is generally one of the main points of attention, as a resuscitator. mine, because without antibiotics modern resuscitation will die, we use antibiotics in several situations: the first is a prophylactic prescription of an antibiotic, for example, a patient goes for a planned surgical operation, this is accompanied by a skin incision before the surgical intervention, therefore, preoperative prophylaxis with antibiotics exists as a reasonable measure to reduce potential, but this is in hospitals, that is, this. as i understand it, they are not taken prophylactically at home, no, this concerns a specific surgical intervention, and this antibiotic is administered there half an hour before the operation with the expectation that it will only work for the duration of the surgical intervention, this is a single administration, this is a single or, in extreme cases, a double administration during the operation, it is repeated again if the operation is long, and if the antibiotic does not work, then what, and if one antibiotic does not work, then some inflammatory... we can select for a long time, because we live in the era of multiresistant bacteria, this means that bacteria have multiple resistance to different groups of antibacterial drugs, therefore here is such a selection, as i said, it is of course not so blind, they simply prescribed one, threw out another, it is selected based on the results of certain bacteriological studies, but nevertheless the number of antibiotics that we can use in our clinical practice is now very limited, and for some reason... as i understand it, well, there are a lot of microbes around us, give, and you said that they communicate with each other with the help of antibiotics, it's just that microbes in general have come up with few antibiotics, four or five pieces, microbes have come up with many antibiotics, the topic of creating an antibiotic turned out to be very economically inexpedient, unfortunately, this topic was already heard before the pandemic, the idea of ​​​​what kind of pharmaceutical company that develops antibiotics... options for bringing the drug to the market, they carry a lot of restrictions, this is very reasonable, since this is a way to protect the patient from some unwanted side effects, everything must be studied in sufficient detail, the moment when the company finally went through this thorny path, a lot of money was spent, antibiotics are released into wide clinical practice, unfortunately, bacteria that live much longer than you and me... longer, yes, in terms of time, i mean in the evolutionary sense, they appeared much earlier, in fact, they are the main inhabitants of our extra-planet, and not you and me, as we think, although we call ourselves kings there, in general, kings are bacteria, in fact, they have many mechanisms to interfere, and what does this mean, you say that development is underway, scientists the company made an antibiotic, but we are forced to take into account the fact that these antibiotics must appear on the market, so the company that brings it to the market must spend this money, and accordingly, when the antibiotic stops functioning after 2-3 years, it turns out that the money is thrown away, well, not to the wind, but in any case it is not very profitable compared to the fact that, for example, a company took and released a drug that lowers blood pressure, what you are saying sounds terrible, not all antibiotics stop. a giant dose of antibiotic, it will be simply toxic, so i work with those doses that are non-toxic for it. in these conditions there is always a possibility, unfortunately, this is a biological law, that some bacterial cell will show resistance, wants to live and will give offspring that will be resistant to this antibiotic. another question is that if the patient is not very seriously ill, then he begins to recover, he has enough strength to cope with the infection. well, relatively speaking, on his own, and the need for a change there is no antibiotic, but in cases of severe patients, complex ones, well, the same covid patients, and they were on artificial ventilation of the lungs due to severe viral damage to the lungs, they had an intubation tube through which bacteria entered from the external environment, and we could not wean them off artificial ventilation of the lungs, because they did not have enough of their own reserves, so during the treatment he recovered, but with... and the lung damage was high enough that i could wean him off artificial ventilation of the lungs, accordingly, he developed a new wave of bacterial infection, these waves, they eventually overwhelmed him and the person died. we watch the badenodcast, i am its host, konstantin severinov, we talk about antibiotics resistant to antibiotics, bacteria with sergei vasilyevich tsarenko. chief resuscitator of the ministry of health of the russian federation, this is what you are describing, it feels like the game over is coming soon, the game will end, yes, if there are no new ones, that is, little by little all the bacteria in the scenario that you are describing should become resistant, insofar as we use antibiotics, you use antibiotics, doctors, yes, and, insofar as antibiotic-resistant microbes arise, that's right, and then it should end soon, yes, and that's very sad. from the market from this, but it means that they have these antibiotics, they just it means that they find it economically inappropriate to develop them, to develop - it means to look for new ones, to look for new ones, yes, for which there is no resistance, for which there is no resistance yet, but this is such a bad infinity, but you will find what you describ

thank you very much, hello, this is the baden baden podcast, i am its host konstantin severinov, todaynd scientific journalist, and we will talk about dietary supplements. hello, alexey, greetings! konstantin, please tell me, dietary supplements are biologically active additives, very popular now, there are also vitamins that are also popular now, but there is also a huge sea of ​​medicine for a variety of diseases, can you give us a definition so that we understand what we are going to talk about? yes, everything is quite clear here, because we have a law on the quality and safety of food products, which has a clear definition of what a biologically active additive is, that is, it is either natural or identical to natural, biologically a substances that are intended for consumption with food products, or as additives to food, and vitamins, here a bunch of interesting questions begin, what is it then? when we talk about medicines, we have pharmacological legislation, we have a pharmacopoeia, we have other things, where it is determined what we can put there, the main active ingredients

, you can simply save money. go eat well and more pleasantly, thank you very much, this was the baden badenkonstantin severinov, today we talked with toxicologist alexey vodovozov about biologically active additives, that is, dietary supplements. hello, this is the podcast lab ask surkova. today my guests are evgeniya gin and petr pavel surkov, specialists in tris. today we have a painful topic, it worries every parent. what is a phone, is it evil or useful and how to build a healthy relationship with gadgets. evgeniya, i want to start by telling you that your child is 10 years old and he does not have a phone. how did you live to such a life? but here it will be correct and honest to say that he has a tablet that lives at home, yes, that is, constant connections that he has with him, he does not have, and i i just don't see it, you were just talking about harm or benefit, we as triz specialists know that there is always harm and benefit in everything, it is important to weigh what is more in a specific situation, of course there is benefit from a phone, however, when we talk about small ch

hope dying from pseudomonas aeruginosa, somehow sad, thank you great, sergey, and this was the baden baden talked about antibiotics and antibiotic resistance, with sergey vasilievich tsarenko, chief resuscitator. of the russian ministry of health . hello, this is the einstein witnesses podcast and its hosts are film historians, natalia ryabshchikova and stanislav didinsky. in this podcast, we talk about why it is now necessary to watch forgotten, little-known, popular, cult. soviet films, how to discover new meanings in them, and get even more pleasure. in order to do this, we we look into the secrets of film archives, re-watch old films, sometimes talk to working filmmakers. today we will talk about the 105th anniversary of the all-russian state institute of cinematography. and in order to do this, we invited three graduates to gika, this is alexander kot, this is nikolay levedev and ivan fverdovsky. hello, hello, we, as historians, of course, love to get to the very beginning, we will say, here are 105 years, 1919, the most inappropriate time to open the world's first film school, absolu

baden—baden, i mean, i was there. >> who can forget i was there? >> who can forget i was there?en meant to be in that hotel, but i'd managed to squeak in there. and so you had a situation where you had the wags out in the doing the lap of the of the park outside the paparazzi were following them and the german media were following them. it was it was it was, as i say, it was it was it was, as i say, it was processional stuff. but as i say, we'll have just we'll have a 700 metre parade today. we'll have speeches and eulogies as you might expect, and some a medley of sven's favourite jazz songs as well, 200 seats and there'll be a big screen, a jumbotron screen outside to allow people to sit at the last words from sven—goran eriksson to beckham were it will be okay. >> yes, exactly. >> yes, exactly. >> i don't know what that means. long term, but i suppose just comforting words, isn't it? maybe. maybe beckham will will reveal that sometime in the future. >> yeah, well, we have just seen david beckham enter the church there at tornby in sweden. that service taking place shortly. of

blue purulent bacillus, somehow it 's generally sad, thank you very much, sergey, and this was the baden badenodcast, we talked about antibiotics and antibiotic resistance, by sergei vasilyevich tsarenko, chief resuscitator of the russian ministry of health. hello, this is the psyche podcast, where i, journalist natalia losyeva and clinical psychologist, phd in psychology michael khors, try to decompose the most complex solitaires of life situations. our current situation is unusual in that the request came from the spouse. alexander. hello, hello, you came to us, hello, with your family problem, your wife anna afraid of all types of transport, afraid of speed, i understand, anya, that this has already begun to cause great discomfort, great inconvenience for your life, for your everyday life, travel, entertainment, please tell me, natalya mikhailovna, please help, in fact, she is afraid of speed, she gets hysterical, she gets to tears, what speed, 120 km/h, no? "she is sometimes afraid even of the sound of the engine, the car has not yet started moving, the sound is just starting to increase,