that can give a strong indication if a drug is going to be impairing, benzodiazepine, often used foreep or anxiety, those generally cause a great deal of sleepiness. then up to the right there's epidemiological evidence so there is evidence that drugs that can make people sleepy do increase the risk of traffic accidents, and then down at the bottom is this focus on standardized studies, taking a look at neuropsychological tests, measuring alertness and arousal, kind of going through actually all the important brain functions, the brain functions are important for driving certainly arousal, sleepiness is very important but it would even go on to things like executive function and in the setting of studies for drugs, again, we can ask drug developers to enroll patients or healthy volunteers and do randomized placebo-controlled trials have positive controls, and get a really good idea of skills important for driving like being able to stay within the lane of the highway. so at this point, we were i think changing to a more sophisticated analysis of drugs. previously we were collecting o