for "nightly business report," i'm bertha coombs in boston. >>> a food and drug administration panel is meeting to discuss muscular dystrophy drugs we reported on late last year. patients and advocates are trying to persuade advisers to support approval of an experimental drug for the disease. last week the fda reiterated a negative earlier assessment of the drug which questioned the clinical trials. >>> today's pain medications are highly effective. many are also hugely addictive. sales are high and rising. so are overdose deaths from prescription pain relievers now exceeding 20,000 a year. here's the first part of our series "the business of pain." >> it's killing the country. it's taking kids as young as 13. it's taking people that are 65 and 70 years old. they're getting addicted. they have no idea how to stop. >> reporter: recovering addict bobby long is one of the faces behind a shocking statistic. about 80% of all opiate medications, the most addictive of painkillers, is consumed by americans. >> opiate prescriptions have skyrocketed and we have currently nearly 250 million pr

bertha coombs has those. >> reporter: express scripts numbers were in line of $1.22 a share.s were slightly shy of expectations at about 24.7 million. the street was looking for slightly more than $25 million. they are raising their guidance and in part because they are amortizing their contract with anthem more quickly than they did. so they are doing a different accounting for the contract with anthem. of course the back story anthem is suing express scripts and wants to terminate the contract because they feel that express scripts has effectively been gouging them, overcharging them for drugs that it purchases for their plans. meantime express scripts has counter sued, but they say in their release that as a result of recent events regarding our discussions with anthem, which culminated in the filing of a lawsuit on march 21st we felt it prudent to consider likelihood of either nonrenewal or renewal on substantially different terms. the likelihood of that had increased. so beginning in march they started amortizing their agreement with anthem more quickly over the life of

and bertha coombs is down at the nynex. >> yes, we are seeing the yield down below 190, and scott nationsd jeff guildberg is joining me, what are you looking for in terms of the statement? >> well, i expect them to be hawkish and the market is telling us while it is turning around a little bit today, we are in the middle of the seven-day losing streak, and the longest in about two years, and that is is because the market expects to be a little bit more hawkish, and i wonder if the fed is going to have a sneak peek at tomorrow's first look at the first quarter gdp, because that is going to inform whether we have two or three rate hikes throughout the year. >> and jeff, what levels are you look agent? the last fed meeting we moved up to the two-handle on the yield in the 10-year, and closed down at 1.91, and what are you looking at today? >> bertha, we are focused on the 2% level again, and to scott's point, he is saying hawkish and i am saying more of the same, u but either way, i'm indifferent. if you see hawkish, rotation out of the stocks and bonds to bring that the yield down, and if s

. >>> bertha coombs has more on other stocks on the move. bertha. >> 50 points away from the 5,000 mark, the nasdaq has not hit above that all year, so we are close to the highs of the year. one big reason why today, apple is strong, on a fresh four-month high. goldman sachs really sort of poupding the table again saying they seed momentum coming back to the stock. certainly true so far, but it's really been the small caps that are doing very well. some of that having to do with some individual names, a lot of semiconductor certainlying on reports tsinghua has revealed a 6% stake in the company, stoking speculation on a take majority bid, and then there's metavation that reportedly has rebuffed sanofi. and bank shares as well, jpmorgan's reds, but take a look at some of those on -- as we're seeing some of the e & p exploration and production names, tuft texas bank names are moving higher on a bit of easing concerning, whether we'll see some of those it loans go into default. back to you. >> bertha, thank very much. >>> pertinent to our theran

bertha coombs has more on what's moving the nasdaq. >> it's a broad based decline most every big sectorch is in the lead on the downside after yesterday's 7% move. i will tell you it is up 7% since april 1st. steve wynn very bullish on macao coming back and a 12% upside from here. wynn shares surging on four times average daily value. there's more talk about bidders trying to take over assets of yahoo!. those preliminary bids are due april 11th. back to you. >> all right, bertha. thank you very much. it is later that's it's ever been and david darst has a new acronym for investors. we're hoping it's a short one. e*trade is all about seizing opportunity. so i'm going to take this opportunity to go off script. so if i wanna go to jersey and check out shotsy tuccerelli's portfolio, what's it to you? or i'm a scottish mason whose assets are made of stone like me heart. papa! you're no son of mine! or perhaps it's time to seize the day. don't just see opportunity, seize it! (applause) - the light bulb, a bright idea if you use the right ones. led bulbs use 85% less energy and last a long tim

we go down to the market site with bertha coombs. >> a lot of disappointing numbers from the big techpanies. as a result, we have the nasdaq down to the worst for the week, worst for the month. seven day in the a row that we have seen the nasdaq slide not coincidentally when you take a look, apple has been down for each of the seven days. apple ending below $100. back below a number of its moving averages, back in bear market territory. after posting those disappointing numbers. really helping to lead to the overall disappointing feeling with tech -- with a lot of bad reports this week. the one thing bucking the trend, well, let's do the david dars acronym, the best gainers were facebook and amazon killing it today. and monster all up on its earnings. and expedia as well. but really as far as those f.a.n.g. numbers it's f.a. that's doing the heavy lifting on the nasdaq these days. back to now. >> well done. see you later. >>> it's been a big week for the dividend players. johnson & johnson, apple, gilead which is down sharply we pointed that out. they all raised their dividend this we