now it's taken a long time to develop drugs for the target a beta. the drug discovery is inherently a lengthy and costly and risky business but on average it takes 14 or 15 years and about a billion dollars to make a drug and the attrition is just massive. so when you start to make candidates nine turn out to be safe enough to enter human clinical trial and only one of nine will make it all the way through to approval with the others failing either because they proved to be unsafe or because they just don't work. in the case of alzheimers disease there's a further hurdle which is there's a protective barrier to keep drugs from entering the brain and it's difficult. a beta was discovered over two decades ago and it took a decade for people to figure out an approach to get access to a beta in the brain and applying that approach they're now half a dozen drugs some in late-stage clinical trials and some are shown to reduce the plaque in the brain of alzheimers patients and in this calendar year in 2012 we should see the clinical results with one of them

when something designed to go shopping at the former's market beta brand may be the place for-to-find it. and the company is all about creating new ideas. >> all of the products are designed to make you the center of all attention and conversation. >> it releases three products each week and customers are a part of the releases. they're encouraged to submit photos for the web site. just about anyone can get 15 minutes of fame. >> we make everything here in small batches to turn it around. >> and success profl ducts get a second rub. bad. >> ideas are dumped. >> these under wear are impregnated with iron. >> that was a bad idea. tsa undies designed to hide private parts when going through screening but tsa fwhot let them test ideas so they never went foo production. some that do make it come from beta brand customers. >> there is. >> this has been an important symbol since his mother gave him a koi kite. >> they can swim up and they get to heaven they'd be trance neermd a dragon he had a dream of turning the kite into a hoody. he says no one understood except beta brand. >> i bought it

level or in your cells that would be the electrons and particles and whatnot it's a beta matter but if you were to listen to the nuclear regulatory commission or the nuclear industry they treat tritium like it's not even radioactive or they say well you know it's mildly radioactive and it dilutes into the environment a beta matter it's thrown off approach and it's a beta emitter and at those intimate levels it does significant health damage it's a clinically proven cause of cancer birth defects and genetic damage right i mean that would knock if it d.n.a. it could knock one of the u.s. it's right out of the chain and put a hole and the reason that you know these are leaks these are steam generator leaks of radioactive tritium steam into the environment as they try to get these things back under control but they allow these tritium releases on a regular basis by permit because they can't filter it out at such a small atom hydrogen it can pass through certain grades of steel it's actually the second smallest thing there is yeah. and so yeah they're having these leaks but they let this be

i've taken some beta off. how it moves relative to the market, calmer stocks, easier moving stocks, more value stocks than high-test stocks because there's a flood of liquidity coming. and i'm not seeing cracks in the bond market. but credit starts are getting fully valued. when that gets fully valued, the assets go into equities. >> cortes, how do you see things today? >> scott, i'm not in mr. fink's camp here. i think asking larry fink and blackrock, one of the largest equity owners in the world, if they like stocks is sort of like asking silvio berlusconi, do you like women? we know what the answer is going to be. if you look at a chart of the s&p and put it with blackrock's stock, it looks almost identical. mr. fink has had a tremendous career. i have admiration for him. but i remember an interview on this network in june of 2008 when he said -- he was talking about lehman specifically. he said that lehman had plenty of liquidity, that it was not a bear stearns situation and he said we were near the bottom

matter it's thrown off a proton it's a beta emitter and at those intimate levels it does significant health damage it's a clinically proven cause of cancer birth defects and genetic damage right i mean that would knock if it d.n.a. it could knock one of the i mean u.s. it's right out of the chain and put a hole and the reason that you know these are leaks these are steam generator leaks of radioactive tritium steam into the environment as they try to get these things back under control but they allow these tritium releases on a regular basis by permit because they can't filter it out it's such a small atom hydrogen can pass through certain grades of steel it's actually the second smallest thing there is yeah right and so yeah they're having these leaks but they let this be discharged into the rivers into the oceans into the air on a regular basis and it's doing itself damage downwind and now the stream that's incredible and so there's no way to filter it there's no way to stop it there's no way to block it and so they just say don't worry be happy do they even bother to detect it wel

>> to be honest, i think you want to avoid the highest beta stock. at this point we've had a big rally and the absolute highest end beta, i'll disagree a little bit, tech, small cap speculative. >> aaron, real quick? >> high-grade corporate bonds. i don't think you get paid to own them. >> even though you are seeing competitive yields though. >> high yield i like. >> gentlemen, thank you very much. good to talk with you as always. thank you, gentlemen. priceline's profits surged. better than 6 # 0% in the fourth quarter. will rising gasoline prices force consumers to cut back on spending? we catch up with jeffery boyd. and one of the kingpins in the business, larry silverstein. before we take a break, take a look at some of the highlights from the guests all day today on cnbc. >>> my own guess, and i really wouldn't put a lot of money on this because of the quirkiness of the statistics, is the unemployment rate at the end of the year will not be much different than it is now. >> legend has it that they like to make money at the pump. the reality is t

it's time to be long equities especially high beta sort of things. it's time to be long gold and commodities. silver looks cheap. it's time to be long junk bonds. it's time to be long art and collectibles. but the one place where i am hesitant to go is into treasuries. when you see all this liquidity coming into the market, the first thing it did was drive up the price of what was deemed to be the lowest risk asset. now that money is flowing out of the lower risk assets into higher risk assets. i think we're setti inting ours up for a correction in treasuries in the next two to three years. >> i agree with you on the macro level. but at some point could the fed have killed the golden goose if inflation gets too high and they have to reverse course? >> it's like inflation, inflation, inflation. the sky is falling, the sky is falling. we've been hearing this since we began qe-2. i remember art laugher put out a piece where he claimed that inflation within 12 months of qe-2 was going to be sky high. being a good monitor myself, milton freeman told us in

>> that is what we call the high beta trade t stuff that is most leveraged in the market, did the bestand the high dividend payers and utilitiies staples have been l k lacking. >> when you get the shifts, does that occur at the beginning of of a new trend, are you calling for a continuation of this trend, do you think ? >> i think it will probably last for a while. but we want to be alert, that we could see a reversal late their year. that has to be careful, that kind of volatility will continue. >> is this a signal that our market is more willing to trade on the fundamentals of our economy rather than the fear factor that -- come frg greece last year? >> it was not until the fear factor started to subside and we have got transaction and we have had a nice run since then. the fundamentals will be carrying us but we have to watch for the big negative events that will come out of europe or china. >> if you like equities you like the higher beta stuff. >> good to see you. thanks for staying. mary thompson, as we enter the close, we have a bigger data week. >> retail sales will have consum

it's been the high beta stocks. the defensive stocks have not worked that well.er high beta area that's -- >> still the dividend payers? >> we like the dividend payers. buy the cheap stocks that have low global exposure. the emerging stocks that have been overweight have done phenomenally earlier this year. the emerging market currency index is up 7% against the u.s. dollar. >> last question. i don't know whether you go out of the united states, but would you look overseas in the fixed income arena? >> absolutely. for us it's the same story, you've got a massive growth in the massive market. >> you want to buy asia local debt? >> diversified local debt outside of the developed market countries with low growth and low interest rates. over time, the structural shift in growth is going to mean a weaker u.s. dollar. we would absolutely diversify out of u.s. dollars into fixed-nm growth. >> david, i'll see you on the "countdown" coming up in about 20 minutes. my co-anchor hosts the very popular syndicated program the "wall street journal" report seen over the weekend

government on a german minister says greece would be better off leaving the years despite securing a new beta. following the nine eleven attacks the us began its anti terror campaign in afghanistan with the liberation of afghan women being used as one of the justifications for overthrowing the town about a decade later we ask what has changed. churchmen dollars to him a little. and coffee as at most i take it that you know i should look up and involve them in joey jackson michigan better than me about. my love for you have already other pleasures make it fit inside. not only peaches and it does that out of. love. but that. you have schools they have that i too would do works with and the mystery is one that woman is asian enjoys and i'm uncivil to say there were many factories. and felt they were still there with two alike and universities. this is for me to. ensure that no one respects the loews here or not all one can. be a pawn for their own good for their protection and therefore that he wrote above. well you know if women don't wear their headscarf they will be harassed raped injured and

one of the most amazing questions i would like to ask, what this entirely rely on the open beta? there are certain kinds of information, and i am not a developer, and that goes into payment. not to say that we all need to pay our bill, but tracking payment on time, and that is kind of like copen data, but layard. even within the city, basing its information systems on open data, there are still layers of governance. they are disclosed to based on your login. i can see a downside where some of this information is not necessarily conducive for all of the nice neighborhood feelings we are trying to encourage. >> the system does offer the ability for staff users as well as on the public side to have a different data available depending on your login. we will be going through a process in determining what the data should be visible for the public. the system will by necessity capture everything. what has been paid, how they were paid, when they were paid. but whether or not that would be made public as a discussion with the media have. president miguel: just a couple of other question

it was being used as a beta a dog in order to train other dogs to fight. the dog named rocky road is expected to be ok. anyone with the permission is asked to call police. -- anyone with information. >> what some are calling the santorum surprise. the former pennsylvania senator riding a wave of the victories in colorado, minnesota,. and brianne carter tells us it is a new sign that the republican race for the white house is far from over. >> rick santorum at the top of the pack today after his tuesday night trifecta. a victory in minnesota colorado, and missouri. >> probably the best two weeks we have had of the campaign fundraising-wise. >> he says that he's the strongest conservative challenger for the general election. cracks of grants for the u.s. senate the same year mitt romney ran for the u.s. senate. i won and he lost. -- i ran for the u.s. senate the same year mitt romney did. >> over the years i have heard a situation is hopeless or heard a long list of reasons things cannot be done, but i have never been good at listening to those kinds of peop

i have lived along the route of the beta breakers for many years, and have had friends that live along the route. each year, we would have a big sale or yard sale. as these people came by, we would raise money for the community housing partnership, protecting the neighbors in the two adjacent houses from urination, garbage, and stuff like that, enhancing the community in raising funds. these are well-noted events that are put on a calendar in advance. i would like to encourage the neighbors to take a proactive approach in helping out the neighborhood. maybe a community group, having something like a bake sale. i will say that one year we made $1,000 charging $10 to use the bathroom. [laughter] i do not know if there is a way for neighborhood organizations to rent a porta-potti for the day, but there are solutions in these communities and they should get together to benefit everyone, helping to maintain the integrity of these festivals. [tone] supervisor mar: thank you for the great work on the entertainment commission. mr. richard roth men? >> thank you for having me here. i live at 38

fur looking for beta, those are the naming to go to. more consistency is the longer term is wells fargo and a little locker than jp mojpmorgan. >> i think moynahan has done a great job. he's taken lots of arrows for what he's done. >> a great job? >> i really do. he was dealt with the worst hand of any bank ceo. maybe he hasn't communicated the best and maybe he's not the most -- the best personality out there, but in terms of operating, stuck to it and got rid of assets. >> those are trades. bank of mesh cities are trades. >> let's get the other guys involved right quick. gras grasso, just to spin it forward. ubs is upgraded emerging markets and u.s. banks. the superregionals they like the be best. do you like either name on a key bank, for for example? >> i like all three. i think that's the place where you put your money, because as pete said before, a lot of other trades are just trades. with we seimone rotates out, they're rotating out of all banks point-blank. >> buffett has a quarter of a billion dollars he invested for the firm

beta version? >> i think you are going to get a couple of things. with microsoft, just going to bring them intoey not just tab let bus touch-based -- a touch-based operating system help with devices that are tablets but also devices that are hybrid devices, opens up microsoft's operating system for a whole new class of application. additionally, you should see a positive impact on the pc market. microsoft will see its oem partners rebuild inventory, allow them to outpace the market. uptick in retail sales and the corporate upgrade cycle progressing are worry about the xp expiration in 2014. a number of factors will be putting upward pressure, not just the pc mark let the next four quarters as well as microsoft's window business. >> pleasure to speak with you, thanks for your time, adam holt of morgan stanley. talk about an ecosystem. microsoft's window 8 to co-spur upward pressure on this whole ecosystem. >> interesting people talked about dell because of david einhorn this week, so now if you just

seriousness, he from the get-go, he didn't even want to release it on dvd but at the time it was like beta. and yeah, i just think he-- in fact, he told me, he said i think it would come across the wrong way. he's like i just don't think it will be the kind of film that i want it to be or other people want it to be. i'm para phrasing from him. >> stephen: what about a prequel. before the alien gets there, and it's just, i want to know more about that family. >> i'm such a sucker-- sucker for prequells. >> stephen: why did dad leave mom, we want to know. >> you could call us the where is mexico version because i say that in the film. nobody obviously got that. >> stephen: that's the heart breaking moment. >> that is where the dad is he's in mexico with sallie. and then she goes and cries at the sink. >> stephen: i don't like sallie. >> neither do i. she's a whore. (cheers and applause) >> stephen: thank you, thank you. now let's talk about the new movie. the new movie is called big miracle. >> yeah. >> stephen: and we have a clip. >> you do. you never show clips. i'm honored. >> stephen: we

we've had in the marketplace, which is a shift towards a more risk on mentality, you know, higher beta stocks in favor, we've seen that in semiconductors. there's been a lot of skepticism about technology stocks for the last couple of years. tech stocks started this year as basically the lowest relative valuation versus the s&p since in over 20 years, and so there has been skepticism about tech companies to grow, as marginally the market has gotten more comfortable with the opportunity to grow, you've seen these beta stocks work and dell is embl emblematic of that. i think that's principally been the driver and dell has participated along with other stocks of that nature like semis. >> are you as positive on an ibm? >> ibm i have a hold or a market perform rating on. it's a stock that's done terrificcally well over the last couple of years. i just think its valuation is relatively full. it's at the very high end of historical metrics so tech is at its low ends of relatively multiples. ibm is at the high end of relative multiples and i don't think there's as much opportunity going forwa

president of the student body ify bait -- phi beta kappa and a rhodes scholar. his performance during his senior year is still statistically one of the most impressive in the history of intercollegiate football. it was capped by all america honors and brilliant play in the cotton bowl. so great was the press interest in the young student athlete, that the new york basketball writers association created the first national invitational basketball tournament largely as a showcase for white and his teammates. white delayed his matriculation at oxford to accept the highest salary ever offered to a player in the national football league, $15,800. this was pre-tv, pre-rosell. following the 1938 season, he spent two terms at oxford studying law but he returned home when world war ii broke out in europe in september 1939. he spent a year at yale law school and won the prize for highest grades in the first year, then took a leave of absence in each of the two succeeding fall terms to continue to play professional football. he was thus able to finance his legal education,

of cuts as the government struggles to keep the country's economy afloat parliament is now due to beta draft bill. by the e.u. and the i.m.f. . and russian civil society take center stage in politics as a group public figure steps up to monitor the upcoming presidential vote with backing from all of the candidates the goal of the so-called voters league is to ensure a fair transparent election. for the top stories and sports is next with paul. hello welcome to the school's headlines here on alex he is good to have you company here's what's coming up. making a racket russia going in there in that davis cup tie with austria old roger federer switzerland the whitewash by the usa. perfectly poised tiger woods is four shots behind leader charlie wade going into the final round of the pebble beach national in california. and mission impossible underdogs down the prepared to face overwhelming favorites ivory coast in the final of the twenty twelve africa cup of nations. but we begin with tennis and team russia still alive in that davis cup tie with austria they say after a dramatic doubles wi

doing so and coming up later in the program here in our keep it alive on his gas tank crossed the beta hurdles in a way of breaking the deadlock of the syrian crisis. for to hold negotiations between all of the different parties and as we know the syrian national council you know one of the main opposition blocks. essentially rejected that offer possibly with some foreign encouragement behind them because one of the stipulations that they made one of the preconditions for the talks was that. should resign so they wanted on the old come to go she owed come of the process as a preliminary condition and so the possibility of negotiations is very unlikely and from my point of view it's starting to resemble a bit what was happening in libya where the opposition consistently refused to engage in any sort of peaceful negotiations. can share your thoughts on the situation in syria log on to our t dot com take part in our online poll well let's take a look what's happening on the web site now this hour forty five percent say it will and with a russia china veto over a third of the respondents t

the possibility of an attack on iran and how justified it would be also the focus of the cost of the beta later today here's a taste of what's ahead. the united states and the european union and its allies have launching what is in effect an economic war against iran saying to the iranian leadership look you can either have your nuclear weapon or you can stay in power you get to choose i think patrick kind of put it really out there very openly it's all about regime change that's what this is about it's not about the nuclear program is a debate in the united states foreign policy community is a long one line only and that is can we do it that is based on efficacy nor is totally the question of should we do it or what would the consequences be of doing it. the u.s. government is about to declare a new war but this time the anime is a virtual one a string of attacks on government websites by you not a mishap or group has policy makers ramping up the rhetoric with talk of a terrorist threat at a tough response but as our lucy confidence reports washington could be turning on its own people.

instead, think about the corporation as a beta customer.y to have early access to your product? will they get it in the marketplace faster? a lot of this comes down to positioning. if you're a product company, you're asking them to take a big gamble to have them help you build it. >> let's move on to the next one. this is about time management. >> as an attorney, i often have times delegating work, trying to control too much, and i was wondering, do you have any best practices for actually delegating work so i can actually get more done? >> this is the problem that so many entrepreneurs have, right? and then we get so into doing our work, we don't have time to do anything else. but the idea of delegating it often seems very time consuming. how do you do? >> you grew a company. >> i'll let jen speak specifically about attorneys. but this notion of voluntary staffing model, when you let people know what tasks need to be done, you'll be surprised how people will volunteer to do the one that intersects with their general interest, and if there'

. >> eric: he may not have been phi beta kappa but he made $5 million. >> kimberly: different societyo go. coming up, palt buchanan is out at msnbc. is the network blacklisting people who don't tow the liberal line? if you leave now i'll send your resume to media matters and tell them you like to work in a dark basement. ♪ ♪ [♪...] >> announcer: bank robbery certainly is a frightening crime. after all, bank robbers stole $43 million in one year. but identity thieves? try 37 billion! and guess how identity thieves are getting some of that money. by taking over our bank accounts. they may not even need your social security number anymore. all an identity thief may need are a couple of simple pieces of information, like your mother's maiden name or the city you were born in, and they could add their name onto your bank accounts in order to make your money their money. you need help. [whoosh, clang] you need lifelock-- the only identity theft protection company that now monitors bank accounts for takeover fraud. lifelock is the proactive identity theft protection company, with an early wa

mountain lion the name of the new application system to make it operate more like iphone and ipad a betaased to developers. full version expected this summer. >>> new act says that google was spying on those -- new accusations that google was spying on those using safari. ads placed by google installed tracking software that bypassed or switched off the privacy settings of people using apple safari's web browser google could track where they went and what they did. google said it stopped the practice it appears it didn't stop until reporters began asking questions. >>> oprah winfrey is the latest celebrity to hop onboard jimmy kimmel's post oscar special. that special airs on february 26th, right here on abc 7 after the oscars. as the countdown to the oscars begins you can find the best videos and blogs by logging on to oscar.com and down low the app for iphones and ipads it will give you access to red carpet and back stage reports almost as good as being there. >> almost. 6:26. the special assistance from santa clara county today that could be a huge help in the grim search for a mass g

. >> microsoft launched its consumer preview of windows 8 today, the first beta version available forwnload to non developers. it is available free online. microsoft raised its ability to perform tasks such as letting users interact with multiple apps simultaneously. microsoft has not set a time line for a final release of windows 8. the u.s. transportation secretary delays plans to mandate rearview mirrors in passenger vehicle. ray lahood is delaying the mandate until later this year, say more study and data analysis needs to be done to ensure the most efficient view possible. the rear view camera requirement is intended to prevent children and other pedestrians from being hit by vehicles when drivers are backing up. more than 200 are killed accidentally and drivers accidentally hit them when backing up. all the fast-food restaurant are required to post a nutritional information for other menu items, consumers may still be confused. a new study reports cal recounts or posted for, meals -- combo meals. >> a bucket of chicken is for more than one person? one soldier hit the jackpot lit

there is a higher beta. >> andy, what do you think?can you stop pretending you understood what he said. >> just roll your eyes. >> i went there once. >> britney has been to hell. >> so neither is muslim. >> britney could become -- >> or i could just move on. obama says he will buy a volt after he is president. you know when he will buy a volt? after he closes get mow. gitmo. by the way, can we talk about how much sarah palin would have been mocked if she said i bet it drives real good. >> yes ssments i. >> it would have been unending. but he gets a pass. why is that? >> i don't understand. >> i don't understand either. these are important questions and you are asking them. >> but are you not answering them. >> i can't answer them. i am limited intelligence. >> that's because you can make fun of whites southern accents. >> but she doesn't have a southern accent, but i take the point. >> i meant a hick. maybe being a little regionalful regionalful -- regional there. socially blacks are a protected class of people. you can't make fun of t

. >> eric: he may not have been phi beta kappa but he made $5 million. >> kimberly: different society to go. coming up, palt buchanan is out at msnbc. is the network blacklisting people who don't tow the liberal line? if you leave now i'll send your resume to media matters and tell them you like to work in a dark basement. ♪ ♪ ♪ [ male announcer ] you're at the age where you don't get thrown by curveballs. ♪ this is the age of knowing how to get things done. so, why let erectile dysfunction get in your way? talk to your doctor about viagra. 20 million men already have. ask your doctor if your heart is healthy enough for sex. do not take viagra if you take nitrates for chest pain; it may cause an unsafe drop in blood pressure. side effects include headache, flushing, upset stomach, and abnormal vision. to avoid long-term injury, seek immediate medical help for an erection lasting more than four hours. stop taking viagra and call your doctor right away if you experience a sudden decrease or loss in vision or hearing. this is the age of taking action. viagra. talk to your doctor. ♪ >> ki