amgen versus biogen ? >> in terms of biogen, trading at 16 times next year's number.cheap. i think it rallied more because people remembered summer of last year when it traded on similar news. next you know, six months later, was trading in half. what i find amazing was the movement of eli lilly today. rallying two all-time highs. $263 price target because of their new diabetes drug. we have been steadfast with eli lilly. you stay with them. >> eli lilly just had an upgrade recently? the alzheimer drug was not even priced into that upgrade. yet here we are. we have this call option. >> i was surprised how much it was off. at one point, it was 10%. i like eli lilly. for me it is driven by -- and thinking weight loss drugs. >> right. >> courtney? >> what is interesting about this too is right now we are getting really good data coming out. the second piece of it is, it needs to go through medicare. we've seen it before where there have been promising drugs and it doesn't get through the medicare reimbursement program. medicare covers like 64 million people and most peop

>> we are cautious on biogen.e overcome and i just remind folks that biogen and aside partnered 250/50. within biogen you mentioned neurology, great for companies there, rental space. maria: thanks so much, we will keep watching the story. dagen, charles, stay right there, the next hour of mornings with maria begins right now. ♪ ♪ maria: millions of floridans in the dark this morning. nicole, what can you tell us. >> good morning, maria, well, more than 2.5 million are without power across the state of florida, some counties waking up to complete darkness. we are talking desoto, charlotte and lee counties, unfortunately some of the areas that saw worst impact of hurricane ian. images coming of southwest florida are unbelievable, maria, and i want to tell you that we are talking about catastrophic storm surge and something that was predicted to happen in the tampa bay area, instead much of this community feels that they were spared as that track really pushed east ward yesterday, still not many city in tampa took a

absolutely shocking. >> shares of biogen?> and i am telling people who are members of the cnbc investing club that this is a time to take profits in biogen and roll into lilly. why? >> where are we on the lilly data have we received anything similar? >> i have my own sources that indicate it's better they have more than -- >> they have not yet given up primary end point, anything like that >> this -- the rollback of the plaque has already been established and done well for lilly. it's other things that matter. the reason why i feel more, i would say, more comfortable recommending lilly is because they have an actual drug that reduces weight >> right completely separate. >> a diabetes drug but that may be the biggest drug of all time. >> so, if, in fact, they're not successful in attacking alzheimer's, it's not as though it's a bet the company kind of thing. we can go back and take a look at biogen stahares, i don't kno, the enormous run-up when we got the initial word i remember being onset, the three of us, talking about, th

biogen is not the only stock in the green with the s&p 500 up 1.5%.is 31 on the vix and you see a rally in 10 year yield dropping 21%. this reflects what's happening across the atlantic with the dollar weaker. and 89 handle on brent crude. stick with us, this is bloomberg. ♪ mark: now keeping you up-to-date here is the first word. president biden is warning oil and gas companies not to price gouge as hurricane ian bears down on florida. pres. biden: my experts informed me of 100 90,000 -- 190,000 barrels will be impacted and that is only less than 2% impacted. this small temporary interruption provides no excuse for price increases at the pump. ma

biogen. look at the gain. lauren: wow.heir alzheimers drug is showing promise ain't that right? lauren: lesenimab is the name of it. so many families are affected by an older person getting alzheimers dementia. surprise phase iii trial of this biogen alzheimers drug help ed as a win. it helps slow cognitive decline in patients of the early stages of alzheimers by 27% in a year and a half. that's pretty significant. likely, they have enough data to get regulatory approval here, and it's being hailed by the wall street community as a potential blockbuster and that's why this stock is up 40%. stuart: i can see how it could be a blockbuster. lauren: very little treatment on the market right now. stuart: when you get older and start to forget things you immediately think have i got alzheimers? lauren: 6 million americans have been diagnosed with alzheimers specifically a form of dementia. stuart: the stock is up nearly 40% right now good stuff. general motors they told their employees you've got to return to work three days a w

shery: asx in biogen say their out timers jug -- alzheimer's drug slows the disease.stone for researchers who have been working for decades to find a reason to blunt the most common type of dementia. it comes with serious side effects, including brain swelling. it is looking for full u.s. approval by the end of march 2023. hong kong-based asset manager value partners looking to double its headcount in singapore. the firm plans to hire staff and relocate some of its portfolio managers and investment analysts to the city space where it now has more than 10 staff. the co-chair says, we are following the money. bloomberg sources say chinese hydrogen fuel cell company is settling a hind -- hong kong ipo as soon as next year. the ipo could raise a few hundred million dollars in the preliminary perspectives could be filed as early as next month. the ipo activity has slumped globally, hong kong has been receptive to the ev battery makers and lithium minors. haidi: why china faces increasing risks from inflation amid ongoing property crisis. we get more on that in the market o

a lot of optimism for biogen. apple, not so much. down about 1.3% to finish the day. this is after bloomberg reported yesterday that they are dialing back plans to ramp up production for the iphone 14. the anticipated demand, they say, has not materialized, so we are seeing that stock down. bitcoin, 19,000. it is kind of stuck in a range here. it has not done anything exciting. it is up higher with the broader equity market, but it has been struggling to hit that $20,000 level. ed: let's stick with the apple story. bloomberg has learned apple's backing off plans to increase production of its new iphones this year. the company had expected a surge in demand, but that has not happened, according to sources. mark, what is the latest report question mark what is going on? mark: in 2022, apple planned to sell 90 million iphone 14 units -- including the plus and the pro. they had this recent extra credit idea for an extra 6 million phones on top of the 90 million, but the extra 6 million is no longer necessary because of concerns about the extra demand not happening in 2022

. >> how is it different than the drug that biogen was testing before, and how is it different than the ones being tested by roche and lily >> actually the primary mode is not to target the plaque in the brain, but the toxic amylo proteins, which is a couple steps before the plaque. we believe this is the reasonr why you see the definitively positive results in this large-scale trial. >> what can you tell us, ivan, about the cost of the drug >> this is very important question, and alzheimer's research for four decades, 25 years ago, we introduced our first treatment for alzheimer's within this -- within it stays for a long time. we understand the sensitivity for the families and patients, and the alzheimer's community, socially responsible pricing is critical for eisai thank you. >> do you think medicare will pay for it >> as you know, the cms has come out with the national coverage determination policy we believe these results answers all the key questions in the cms policy we cannot wait to share this port data with the counter ms and continue a productive dialogue over the past few m

. >>> the justice department says biogen settled the whistleblower lawsuit. suit accused the company of paying doctors kickbacks for ms. biogen did not speak out on the settlement >>> ftx won the auction to but the lender voyager digital with the bid of $1.4 billion. the majority of that is for the estimated price of all voyager cryptocurrency inv the claims against cryptocurrency hedge fund will remain with the estate frank, crypto is on the move with bitcoin above 20,000. >> pippa, thank you. >>> turning to the developing story of the british pound rebounding after hitting an all-time low against the dollar. bank of england vowing intervention joumanna bercetche is outside the boe in london with more on the story. good morning, joumanna what steps is the central bank weighing on this matter? >> reporter: frank, the pound was eight points lower in the last couple days 10-year gilt up 100 basis points the eventual are important the reason why investors are picking on the uk is a combination of loose monetary policy and expansion fiscal. on thursday, we had th

, alcohol, there's biogen in the premarket.s over the death of heleyna hutchins. filing state funds to go to prosecution of up to four people in connection with the shooting while not confirming the charges she did write one of the possible defendants is well-known movie actor alec baldwin. there could be 4 separate jury trials, baldwin denied firing the gun last october. he said it was an accident. finally there's this. here is one unique way to apply for a job. carley blackburn sending nike a huge cake with her edible resume printed on the top. the 21-year-old not applying for open position but the team she wants to join at nike. they were holding a party that she knew about. the just do it celebration party so she had it sent to the party. i think they should hire her if anybody from nike is watching. maria: somebody is going the hire her, very creative. thank you, cheryl. one of the big stories of the morning, congressional budget office out with its report on president biden's student loan bailout. the cbo says it will cos

. >>> a break through at biogen. new data surrounding the experimental alzheimer's drug has the stock soaring up 35%. >>> we're checking in on the 2022 cnbc stocks draft how is seymour alpha feeling about his team five years later. hear from tim coming up. at fidelity, your dedicated advisor will help you create a comprehensive wealth plan for your full financial picture. with the right balance of risk and reward. so you can enjoy more of...this. this is the planning effect. lily! welcome to our third bark-ery. oh, i can tell business is going through the “woof”. but seriously we need a reliable way to help keep everyone connected from wherever we go. well at at&t we'll help you find the right wireless plan for you. so, you can stay connected to all your drivers and stores on america's most reliable 5g network. that sounds just paw-fect. terrier-iffic i labra-dore you round of a-paws at&t 5g is fast, reliable and secure for your business. the hiring process used to be the death of me. but with upwork... with upwork t

that's big news right there for biogen and the country. break, senator joe manchin caves in in order to avoid government shutdown after dems renege him. fed up with philly, citizens outraged of shocking crime and no sign of stopping. it is today's hot-topic buzz. hurricane ian strengths to category 4 storms as it barrels to florida. we are tracking the storm all morning long. stay with us. back in a minute. ♪ ♪ ♪ [ "back to life" by soul ii soul ] what if you could change your surroundings with the touch of a finger? now you can. biometric id... inside the innovative, new c-class. ♪ this... is the planning effect. this is how it feels to know you have a wealth plan that covers everything that's important to you. this is what it's like to have a dedicated fidelity advisor looking at your full financial picture. making sure you have the right balance of risk and reward. and helping you plan for future generations. this is "the planning effect" from fidelity. maria: welcome back, senate advancing budget bill last night after senator joe manch

biogen better by 39% and prfena by 32% and bank of america raised isai to a buy on the news the companys developing its own alzheimers therapy. along with other drug companies, eli lily having a nice day up 7.25% and rosh by 6.75%. a hard turn here but it's to docu sign announcing its restructuring plan. this is the electronic company that was a pandemic favorite and plans to reduce the work force by 9%. docusign will incure charges of $30 to $40 million in connection with the restructuring plan but listen, something they've got to do. shares right now a. lyft, look at those. they are up 2.6% aftere hailing company said it's going to freeze hiring through the end of the year. the news comes after lyft in early august said that it would slow hiring dramatically as it sought to cut down costs. stock has been struggling year to date down 66%. lockheed martin and l3 both moving higher and l3 getting the bigger chunk up about 1% and lockheed martin up one-third percent after a $1.1 billion package of weapons and equipment for ukraine. these two were initially lower after wells fargo downgrad

horton and others and a huge win for biogen, and maybe some alzheimer's sufferers. very encouraging news about drug trials around an alzheimer's drug shares of biogen are up a 37.5% today. big win there and hopefully a bigger win for those patients. we're going to get more on stocks ahead, but we have to begin with the big market macro story of the day that is the bank of england intervening, trying to stabilize its debt market after they sold off massively and there were very real fears of some kind of contagion. british bonds are known as guilts the b.o.e. saying it will suspend the planned start of guilt selling and begin temporarily buying long-dated bonds. in other words, a huge flip-flop. it's all part of an effort to try to calm the chaos that began when the government announced its budget plans let's try to make sense of all of this and bring in steve liesman by phone it's kind of a complicated story. i know we don't talk about british bonds very much here on cnbc, but this was a gigantic global market story. >> for sure, brian it's a dramatic move it's an a

biogen offered and paid remuneration to health care professionals who spoke out on biogen speaker programsonex, tysabi >> where are they with purdue? >> it was in a class of its own. this was not opioids >> the plethora of companies i have had to visit in the last two weeks. home depot they are so ready for lower everything because that's when people start fixing their house up a lot of stuff they sell has come down. their margins are going to be good they are very good at what they do i would look at home depot and costco they had a great quarter nobody cares >> two important names, especially when there is a hurricane. ian did crash into western cuba. >> they have to rebuild. that means home depot. >> tampa looking at storm surges to a to 10 feet. generac is leading >> generac wasn't that big a deal then. generac is a rather amazing stock. they have been hammered, hammered, hammered >> storm surge and rain is the main concern i think in the tampa area >> right >> perhaps as much as 10 feet. how tampa bay itself is going to be able to handle that >> meantime, chevron, bp halted work and o

the agreement settles a whistleblower lawsuit brought by a form are biogen employee. saying about the crime crisis. the effort to avoid a government shutdown and the latest on the midterms. plus "tuesday tweets." yours could be on tonight's show. you never snow ♪ ♪ er future. so we're hard at work, helping them achieve financial freedom. we're investing for our clients in the projects that power our economy. from the plains to the coasts, we help americans invest for their future. and help communities thrive. - hiring is step one when it comes to our growth. we can't open a new shop or a new location without the right people in place. i couldn't keep up until i found ziprecruiter. ziprecruiter helps us get out there quickly and get us qualified candidates quickly. they sent us applicants that matched what i was looking for. i've hired for every role, entry-level technicians, service advisors, store managers. ziprecruiter helps me find all the right people, even the most difficult jobs to fill. - [announcer] ziprecruiter, rated the number one hiring site. try it for fr

breakthrough in the fight against alzheimer's tonight and experimental drug being developed by acai and biogen slowed progression of the memory robbing disease apparently by 27% that's according to the companies the results of not yet been peer-reviewed, but they are encouraging and have been submitted as an application to the fda. however a side effect experience by some people on the medication includes a small brain bleeds and brain swelling the symptoms were detected in brain imaging but rarely caused those symptoms or study of course being done in the south bay levi stadium was alive tonight, but it wasn't from fans of american football. it was tuesday night football though. the mexico men's national soccer team taking on columbia and the fans showed up in force and showed up early you're looking at the view from sky 7, which spotted cars full of tailgaters even there before three o'clock in the afternoon abc 7 news reporter amanda. studio has our sights and sounds from santa clara. niners red and gold replaced by green and yellow at levi's stadium an estimated. 6,000 people showed up for

breakthrough in the fight against alzheimer's tonight and experimental drug being developed by acai and biogenion of the memory robbing disease apparently by 27% that's according to the companies the results of not yet been peer-reviewed, but they are encouraging and have been submitted as an application to the fda. however a side effect experience by some people on the medication includes a small brain bleeds and brain swelling the symptoms were detected in brain imaging but rarely caused those symptoms or study of course being done in the south bay levi stadium was alive tonight, but it wasn't from fans of american football. it was tuesday night football though. the mexico men's national soccer team taking on columbia and the fans showed up in force and showed up early you're looking at the view from sky 7, which spotted cars full of tailgaters even there before three o'clock in the afternoon abc 7 news reporter amanda. studio has our sights and sounds from santa clara. niners red and gold replaced by green and yellow at levi's stadium an estimated. 6,000 people showed up for a chance to che

preparing for eco , point applications are carried out, as well as wrapping mineral salts, vitamins, biogenic stimulants affect the neuroendocrine system in the first place, stimulating the thyroid gland. mud therapy has a general stimulating effect on the body, including the ovaries , in the same way that hormones are included in the composition of the mud. yes, it is different for the reproductive system - this is a rejuvenating effect - this is a stimulating effect, anti-inflammatory antibacterial effect. and in general, there are good results with e, violation of e, with e, infertility. yes, especially in case of difficult tonal infertility, not only a therapeutic effect, but also a special pleasure will give the patient therapy, a proven procedure time and scientifically proven to be effective. the method is based on the use of natural mineral waters for the prevention or treatment of various diseases, including infertility, in addition to mineral waters, various additives are used. coniferous concentrate to relieve the general tension of the nervous system or the substance pantohematoge

let's get you the latest check of your business flash headlines, biogenic says their alzheimer's drugs the results from a final phase trial are a major milestone for researchers who have been working for decades to find a treatment for one of the most common types of dementia. however, the treatment comes with serious side effects including brain swelling. they will apply for full u.s. approval by the end of arch 2023. twitter is accusing elon musk and his lawyers of not handing over text message exchanges with morgan stanley ceo james gorman and also chairman larry ellison. they have subpoenaed the text ahead of the trial. morgan stanley was chief financial advisor while ellison said he would back the deal. hong kong asset manager value partners are expecting to double their headcount in singapore. they're planning to hire or relocate staff and investment management's to the city state, where it now has fewer than 10 staff. value partners cochairman says you're following the money. network cofounder and ceo is stepping down of the crypto start up as it forces its way to bankruptcy. ch

this is really connected to what happened with biogen and we are watching some of these things and southnd across the region. we talk about the debuts. yvonne: the worst trading debut of 2022. dropping more than 30% right now. one falling almost 8%. we are still lower by about 4% here today. plenty more in the next hour of bloomberg markets asia. here's a glance of markets here. dollar ever stronger again. the rest of the markets looking better. this is bloomberg. as a business owner, your bottom line is always top of mind. so start saving by switching to the mobile service designed for small business: comcast business mobile. flexible data plans mean you can get unlimited data or pay by the gig. all on the most reliable 5g network. with no line activation fees or term contracts. saving you up to $500 a year. and it's only available to comcast business internet customers. so boost your bottom line by switching today. comcast business. powering possibilities. ™ hi, i'm jason and i've lost 202 pounds on golo. being a veteran, the transition from the military into civilian life causes a lot

study the late stage trial has been anticipated after a drug last year also developed by ee sigh and biogen the chip sector falling today following insider reports that most of the major clients except for apple, they've cut orders for next year this includes amd, nvidia, and qualcomm, cutting its revenue forecast for 2023. finally, blackberry, that stock is lower even though the company reported a smaller than expected second quarter loss. it also beat revenue forecast. revenue from its cybersecurity business fell as customers reined in spending due to economic uncertainty. >>> time now for something random but interesting of course, for that, we send it out to our brian sullivan. >> in today's rbi, let's talk real estate because we know that housing has been slowing down in a lot of cities and towns across america, sometimes very quickly. the pandemic boom is petering out, but not everywhere, it would siege and here on cnbc, you know we always love to show you some eye-popping rey you can buy for tens of millions of particulars. that's what robert frank does best today we're going to go d

you know, we will find out to see how they are going the price it but you're right, earlier when biogen with a new drug that we are learning about now, lecanemab had come out with another drug earlier this year and the fda basically said, yes, all systems go even though experts that voted against it unanimously and what many see as political move try to give a signal to the company and say, hey, we are still going to support it and medicare said we are not going to pay for it. so that was a complete disaster and this is very different. maria: so the fda is considering whether or not to grant conditional early approval for this drug. do you expect it soon and do you think it's indicative of classic drug, more companies perhaps investing in this area of the market? doctor: yes, because the market size is tremendous. remember, alzheimer's and dementia are very closely related and we don't really understand the difference and if you look at the total population of seniors with dementia, it may be as high for 5% for some type of dementia. the market size is tremendous and there's a ton of in

yesterday we had the biogen alzheimer's drug, today we're talking about als.g in the right direction. so thanks for that. great reporting there. we want to bring you this moment of celebration here on fox business. we're all very proud of larry kudlow. last night my colleague and host of kudlow, larry, was hand in was honoredfor his leadership il thought. he won the prize at the ronald a reagan presidential library. watch this. >> i want to thank national review for this honor. this is a wonderful thing. we are in the midst today of a very fierce battle between the progressives or the socialists, the radicals, who want to tear apart our history, so we have a fight on our hands, a serious fight. it is a fight for the soul and existence of america. maria: we could of not be more proud of larry who just notched the high ofest rated show on cable. keep on going, larry. congratulations to you. meanwhile, hurricane ian expected to make landfall in south carolina hours from now, bringing a life threatening storm surge and dangerous winds after gaining strength in the

biogen among them. but i asked about the bear market and your claim that it is getting tired. where, again, is the evidence of that beyond a colleague of yours who says i'm sick of hearing about the fed? >> consumer nondurables have stopped outperforming. utilities were one of the biggest down groups in the down market yesterday when you look at the places where you've gone to hide, when you look at the flows of capital, it's leaving bond funds now. it's not leaving stock funds the flows into stocks have increased and are accelerated. the things that would let you believe there's more stocks to be sold, and that would give you more long-term evidence of a bear market, those are starting to go away and they're giving rise to all these interesting green shoots >> let's talk a little bit where you see an attractive risk/reward. i want to go to las vegas sands, a company i cover and a company i know a lot about but i just want to lead into this las vegas sands is part of a broader group in gaming where there's been generally a radio real disconnect between what the companies are r

another strong performer as of late, and there's been a lot of positive developments in the trials of biogener's drug, and it's obviously something that afflicts a ton of people globally and all these stocks benefit from the investment and those spaces >> joe, when we did our stock summit many months ago you picked united health, and health care is your space you own abbvie today, cgen. >> i've been active there and sold recently, used the capital to go into cgen by ownership of merck on any pull back i'd like to own to. bristol myers i don't own it that's been working well got my eye on intuitive surgical right here and might take a position on that name. also keeping an eye on abbvie and i think a name that brin in the past and i apologize if she's still in it that's pulled back recently and looks attractive here. >> you mentioned abbvie. everyone seems to like that. let's talk about energy. coming up still leading on the year we'll find out how we're playing it into the end of this year plus for hispanic heritage month cnbc celebrating our teammates and contributors here's gena sanchez. >

although that biogen with nudes, by the way, was great news for society.eimer's -- >> couldn't agree more. charles: always a pleasure. of course, we never get enough time to discuss it all. i also love to write about it. i do it every single day, so check out my free commentary. go to w street.com, i i know you'll like it. >>> october, it's got a reputation as a bear market killer. luckily, we've got one of the best market historians in the world, ryan dietrich here at 2:45. but first, the jobs market is still a beast, but should it dictate fed policy? nancy tengler on deck. ♪ and i'll be taking care of business every day. ♪ taking care of business every way. ♪ i'll be taking care of business -- ♪ taking care of business and working overtime ♪ can actually make it work. if you have this... and you get this... you could end up with this... unexpected out-of-pocket costs. which for those on medicare, or soon to be, is a good reason to take charge of your health care. so consider this. an aarp medicare supplement insurance plan from unitedhealthcare. why? bec

. >> we are continuous cycle with biogen rated methane. it's been going on for a long time.rrived in the new world there were 0 million buffalo ranging in the north american prairies, it is not something new. it is not adding to the problem. it is just a part of a cycle. >> bret: how much of this deals with that. >> not much conservation farm forever farm do your agriculture that helps the air and the water. >> bret: the law dedicates $1.4 billion to make sure farm land does not turn into roads, cities or other developments. for wind and solar projects companies receive 10% tax credit. >> these are just a value-added proposition. if they put a wind turbine on their land they can make money while they are growing their crops, while they are producing dairy or whatever their agriculture production is. >> but farm land is still decreasing at a rate of 2,000 acres per day as renewable energy expands. >> to reach net zero by 2050, we are going to need to mobilize trillions of dollars in financing. to harness both private and public sector resources. >> bret: to reach president bi

which is weird to say out loud, biogen's got a good development on an alzheimer's drug use and that stock up 50% because it's been shown to be effective at reducing cognitive decline. so it's good to have lines a mortgage. refi, zur down. get this 84% year over year. a lender of, you know, today. new originations are down. 29% and kyrie irving we feel bad for him. but he said he's lost about 100 million dollars four-year extension because he refused to get vaccinated last year. you know, it's funny. we're talking about that yesterday to just the just the 5th to have enough in the bank that you can eat 100 million dollar loss and be ok with it. >> it's my pa going, but i'm sure he'll be fine with that. >> he's a coach anywhere. you guys gets coaches fired because he's tough to play with now doesn't play by the rules. no 100 million dollars. a lot of money. on a a all right. i got to get your thoughts to hurricane. and that's been one of the big stories that we've been talking about. >> it's about to make landfall in florida as an almost category 5 storm winds upwards of one. 55 to one 60 m

gains this month in fact, posh mark posting its best month ever, biotech booming, as well, because of biogens on pace for its best month since 2000, after that promising data on its alzheimer's drug not the only one, though regeneron up 20% ely lilly up 8%. it just hit an all-time high two days ago every single one of these stocks are up 10 to 20% since january even in the worst markets, like jim says, there are bull markets somewhere. let's get a cnbc news update with tyler mathisen. >> brian, thank you very much. here's what's happening at this hour fresh video of the tragic damage in ft. myers beach severe damage to many homes, cars flipped over in parking lots governor desantis says that rescue crews have gone door-to-door to more than 3,000 homes in the hardest-hit areas in san diego, a sailor has been found not guilty of setting a fire, that destroyed a $1 billion navy warship brian maze was charged with arson that led to the massive blaze aboard the are shard g-7 foreign ministers are posing steeper costs on russia for annexing parts of ukraine. the nations also say that they will nev

report, seisi already asked for the drug to be signed off last year they've approved a drug from biogenen a bust they're hesitant to prescribe that over questions it actually works. >>> home refinance applications plummet and that's what's topping cnbc's on the money. >>> applications to refinance a home loan declined 11% last week that's according to the mortgage bankers association. home rephi applications down 84% from a year ago hitting a 22-year low. more borrowers staying away because of higher mortgage rates. the rate on the popular 30-year fixed mortgage is now nearing 7% >>> bernie madoff victims are getting more than their money back the latest round, $372 million to about 27,000 victims. that brings the total amount distributed to more than $4 billion since madoff's firm collapsed in 2008. madoff's total fraud estimated as high as $64 billion >>> and lebron james is taking his talents to the pickle ball court. james is headlining an ownership group that's buying a pro pickle ball team. other high profile owners include super bowl champ drew brees, the milwaukee bucks co-owner

switch to xfinity mobile today. >>> and we showed you this earlier, shares of biogen surging after amer's dramatica slowed progress progression of the disease. let's bring in dr. scott gottlieb we have him now? good then let me know that. hey, doctor, are you there >> how are you, yes, i'm here. >> so there has been a previous study that wasn't nearly as robust at this point are you inclined to say this is the one to pay attention to or is there still some question? does the thesis that the amyloid plaque is the cause and target for therapeutics, has that been proven or the evidence is getting stronger >> well, certainly the evidence is getting stronger. i see three main things coming out. first i think this is an important result that will prompt people to reconsider the entire approach to the treatment of alzheimer's to your point the long running debate has been whether drugs that can remove the existing plaque would have a benefit and some believed that the plaque was merely the result of the process and by targeting you are not assessing the underlying cause of the deal. i think

biogen has also applied for accelerated approval from the fda for the drug, and a decision is expectedhat's encouraging the encouraging news. we haven't seen a lot of progress in terms of alzheimer's. yeah. alright time at 6 48 salads back. he's going to tell us is that truck that was in that traffic jam. moved moved at all. but you're you're covering. everything did move it did you were you were everyone was wondering. is that picture frozen? no, it wasn't frozen and things are getting better. let me just go in order , though, if you will, because i'll just get i'll move from contra costa county from east to west. first of all, i do have to mention that marsh creek road is closed. for a stretch near hoffman lane because of a deadly collision, so you have to use another way to get through brentwood that's causing some local delays their highway four and 6 80 or slow because of an earlier crash in walnut creek. they had it on the shoulder. but look at the damage is done as you drive west, and you can see how highway four is slow their traffic on the richmond bridge. that truck is finall

the pharmaceutical companies eisai and biogen say it was found to reduce memory decline when given ineet high. 0ur correspondent azadeh moshiri is in st petersburg in florida with the latest. now the hurricane hasn't even made landfall right now, and yet its impacts are still being felt across florida. in fact, more than 200,000 power outages have already happened. now, we don't know exactly where the hurricane's going to make landfall nor how high a category of storm that it will be, but officials have said two things that they know for certain. it will be historic, and it will be life—threatening. here's more in my report. a life—threatening hurricane is now barrelling towards america's sunshine state and put millions under evacuation orders across the west coast. ian is unpredictable. it's already caused widespread damage in cuba, wiping out power to the country's entire grid, with some residents killed. but now its hurricane—force winds are leaving the gulf of mexico and taking aim at florida's coast. this satellite image shows the eye of the hurricane packed with lightning. clear

i'm trying to get their weight drug and i believe their alzheimer's is going to be as good as biogen drug. loses weight no downside. >> send me more information. i'm interested another day of washout let's get to bob pisani. >> good morning, guys. and we basically given up all the gains that we had yesterday. david had a great point, it's really hard to put on risk in this market because the market's picking your pocket here day after day, you're getting faked out here, and it's making it really difficult so i use very simple metrics for risk on, risk off arc innovation, semiconductors, metals and mining, these are good examples of risk on, risk off, all three of them down 2.5 to 4% today. everything else within that range. banks, consumer staples doing a little bit better, but not much bett better if you look at mega cap tech, bank of america downgrade for apple here, lowest level since july apple's held up better but it was 176 in august so we're down 15% since then there's amd and nvidia, down microsoft is down about 28% so far this year. so, yes, all right, comparatively, apple's

bottom and is subject to decay processes, thereby substances enter the natural circulation in form of biogensat are necessary for the existence of living organisms ecologists. such an action is considered extremely important by juveniles, carp will be released into one of the reservoirs of our region in october. more efficient work. how to recognize fake vacancies to protect your rights if you were deceived, we will discuss with an expert after the news? andrey shevtsov continues to work live in the studio hello today, the final fifth day of the referendum of the people's republic of donbass and kherson zaporizhia region , those who have not yet filled out the ballots are making a historic choice about joining russia. today it is possible to come to a stationary polling station on previous days for the security of mobile groups. citizens were bypassed at the place of residence and work in all four regions, the voting has already been recognized as valid, since the turnout exceeded the required 50%. according to local central election commissions. in the donetsk people's republic following the

moderna, freeport, twitter, biogen, winners on s&p 500. there's some winners. there., regeneron, unchanged and antigen down. not much movement to the upside today. look as we may. ten year treasury, yield is going up, or it was, now it's starting to head south a bit. 3.26% is the ten year. price of gold, $17.22 per ounce. bitcoin just above $19,000 per coin, $19,143. price of oil, low 80s. $83 a barrel. nat gas, $7.97 and rising just a little. very volatile comity. average price of gallon of gas down one cent to $3.75. the cheapest gas in america is in texas, $3.21 for regular there. buckingham palace says doctors are concerned for queen elizabeth's health. members of the royal family gathering around her at her especially estate in scotland. >> cool your home and make sure that thermostat is above 78 degrees. still feels cool beyond words. i walked in at 78 degrees and felt like i needed a jacket. stu: i wonder if governor newsom read this morning's wall street journaling that takes his climate policy to pieces. we'll be back. ♪ stu: dow is up 100 and nasdaq down 64

biogen says that their medicine slows the effects of all dimers/ apple is backing up plans to increasection of its new iphone this year. the company had expected a surge in demand but that has not happened. apple him to produce 90 million handsets in the second half of the year, roughly the same level as last year. global news 24 hours a day, on-air, and on bloomberg quicktake, powered by more than 2700 journalists and analysts in more than 120 countries. i'm lisa mateo. this is bloomberg. >> watching the pound today will be crucial. potentially with the pound will do in the next week could determine the future of this government. the long end of the u.k. bond market has been essentially trading like a default in the u.k. that is causing immense losses. jonathan: maybe the chancellor not looking at the polls but at pound sterling this morning. down .6% on the s&p. nasdaq 100, down 1%. the dollar still stronger. the main event is right here in the u.k., the bank of england coming out and announcing a guilt purchase operation, buying a long and of the yield curve in the u.k. bond market.