i want to bring in bonnie fuller of hollywoodlife.com. you hear this about anyone. do you know anything about whether he had any idea he had any kind of heart problem or anything or was this suddenly out of the blue on vacation? >> i think from everything we are hearing this is completely and uttererly out of the blue. no known heart issues. james gandolfini was a little bit heavy so a little bit overweight but lots of people are overweight and don't have heart attacks. he was only 51 years old. and i think clearly he didn't think he had any health issues. he was in italy to attend a film festival in sicily. he thought he was in good health. >> when we first saw this headline i don't know what your reaction was but we heard this from somebody in the italian-american community. cnn started looking into this and everybody thought it was a hoax at first. did you have the same reaction? >> we were shocked. what i think is so sad is he has children. he has a young daughter who was just born about a year ago and has teenage son from his previou

and the lovely bonnie fuller. let me s

let's begin the discussion with larry king who joins us by phone tonight, bonnie fuller and our chief medical correspondent dr. s sanj sanjaygupta. what would you questions be? >> clearly, this is young to have a heart attack even when you look at, you know, any preexisting health conditions. average age of someone having a first heart attack if this is what we're talking about is usually in the mid 60s. john as you suggest it's important here, there is very limited information that we know and so i think the medical personnel, the people figuring this out on the ground there will want to know are there any other potential risk factors here? if this was, in fact, heart disease, heart attacks typically cause something known as a cart yak arrest. the heart attack itself is caused because there is not enough blood flow to the heart but what can cause death is the heart as a result of that goes into abnormal rhythms but other things can cause abnormal rhythms as well. did he have a prekprisiexisting condition he didn't know about? was there medications? was there a stroke involved? could

and bonnie fuller who has been here many times also. so let me start with you karen because i was reading your book over the weekend and you basically -- i mean there are so many things in there to talk about. you're a little bit