the brca gene genie is newsworthy and noteworthy because it is unusual. —— the brca gene is newsworthyverall population have a brca gene. it's also known as the angelina jolie brcagene. if you have the brca gene, you jolie brcagene. if you have the brca gene, you are likely to be younger. it is because you have this genetic predisposition that you are likely to get cancer earlier. 0ne predisposition that you are likely to get cancer earlier. one of the key things is the age of the patient as well as whether they've got mothers or sisters directly affected. it's the old story, isn't it? you need to think about these things, you need to get clear advice and agreement from your oncologist 01’ and agreement from your oncologist or whoever is in charge of your case? that is right. the good news is the cure that is right. the good news is the cu re rates that is right. the good news is the cure rates for breast cancer are going up all the time. we are understanding more and more about it. the treatments are getting more and more individualised and there are good outcomes. the majority of wom

one in a50 women carry faulty brca genes.d many women with a strong family history of breast cancer opt for preventative double mastectomies, which almost eliminates the risk. like angelina jolie, the actress and campaigner who revealed she had preventative surgery, it led to greatly—raised awareness of brca gene mutations. this study looked only at young women, like laura. 95% of breast cancers are in the over—40s. laura says if she had her time again, she might have delayed having a double mastectomy, but she has no regrets. fergus walsh, bbc news. it's the queen as you've never seen or heard her before. to mark the 65th anniversary of her coronation in 1953, her majesty has been giving a unique insight into the day and what it meant to her. she's been speaking to the royal commentator alastair bruce for a bbc programme. a key piece of advice for any would—be monarch — don't look down — as our royal correspondent nicholas witchell reports. she famously doesn't do interviews. this is probably as close as she'll get. a conver

one in a50 women carry faulty brca genes.nce of getting breast cancer, and many women with a strong family history of breast cancer opt for preventative double mastectomies, which almost eliminate the risk. like angelina jolie, the actress and campaigner who revealed she had preventative surgery, which led to greatly raised awareness of brca gene mutations. this study looked only at young women like laura. 97% of breast cancers are in the over a05. laura say5 of breast cancers are in the over a05. laura says if she had her time again, she might have delayed having again, she might have delayed having a double mastectomy, but she has no regrets. fergus wal5h, bbc news. our top story this evening. donald trump says he won't be coming to london and he's accused of racism over alleged comments about african countries. still to come... music and taking the airwaves by storm — the 21—year—old from norway who's the bbc‘s sound of 2018. coming up on sport5day on bbc news. johanna konta carries british hopes at the first tennis major

one in a50 women carry faulty brca genes.chance of getting breast cancer, and many women with a strong family history of breast cancer opt for preventative double mastectomies, which almost eliminates the risk. like angelina jolie, the actress and campaigner who revealed she had preventative surgery, it led to greatly—raised awareness of brca gene mutations. this study looked only at young women, like laura. 95% of breast cancers are in the over 40s. laura says if she had her time again, she might have delayed having a double mastectomy, but she has no regrets. fergus walsh, bbc news. it's the queen as you've never seen or heard her before. to mark the 65th anniversary of her coronation in 1953, her majesty has been giving a unique insight into the day and what it meant to her. she's been speaking to the royal commentator alastair bruce for a bbc programme. a key piece of advice for any would be monarch — don't look down — as our royal correspondent nicholas witchell reports. she famously doesn't do interviews. this is probab

they get tested and find they have the brca gene and do not have breast cancer.ess angelina jolie, decide to have a double mastectomy. this is totally separate from that. that will probably continue. there is one limitation on this study. 0nly will probably continue. there is one limitation on this study. only about 596 limitation on this study. only about 5% of breast cancer cases occur in that very young age group. we do not know about the long—term survival of women with breast cancer who get it ata women with breast cancer who get it at a much older age are more commonly say at the menopause or later. a huge fire engulfed a section of nottingham railway station this morning. around 60 firefighters tackled the blaze, which began at about 6.30am. no—one was injured, but trains are still not stopping at the station and travellers are being warned to avoid the area. phil mackie reports. the severe fire rapidly spread through the recently renovated station at the start of this morning's rush—hour. 60 firefighters were called to deal with the blaze while passengers

one in a50 women carry faulty brca genes. a strong family history of breast cancer opt for preventative double mastectomies,

the treatment was based upon their breast—cancer status rather than the brca status.t first the headlines on bbc news: donald trump cancels his visit to the uk next month — but downing street insists the "strong and deep" partnership "will endure" dozens of firefighters have been battling a huge blaze at nottingham railway station. the station is shut causing major travel disruption and a breakthrough in talks to form a new government in germany between chancellor angela merkel‘s christian democrats and their former coalition partners, the social democrats. in the business news. bank customers across the uk as of tomorrow will be able to securely share their financial information with other regulated firms. all they need to do is give their permission. the so—called open banking regime aims to help consumers get better deals. more of this in a second. good news for consumers — businesses will no longer be able to charge you when you use a debit or credit card from saturday. the new law which bans surcharges is collectively said to save consumers getting on for 500 mil

one in a50 women carry faulty brca genes. chance of getting breast cancer, and many women with a strong family history of breast cancer opt for preventative double mastectomies, which almost eliminates the risk. like angelina jolie, the actress and campaigner who revealed she had preventative surgery, it led to greatly—raised awareness of brca gene mutations. this study looked only at young women, like laura. 95% of breast cancers are in the over 40s. laura says if she had her time again, she might have delayed having a double mastectomy, but she has no regrets. fergus walsh, bbc news. you can keep up—to—date with all our stories including news, business and sport on the website or reaction and analysis from around the world including updated live pages. reports from our correspondence based on 80 international locations and eyewitness accounts. just go to the website. president trump sparks outrage after allegedly making racist comments about african countries. a surgeon who branded his initials on to the livers of two trans

one in a50 women carry faulty brca genes.and many women with a strong family history of breast cancer opt for preventative double mastectomies, which almost eliminates the risk. like angelina jolie, the actress and campaigner who revealed she had preventative surgery, it led to greatly—raised awareness of brca gene mutations. this study looked only at young women, like laura. 95% of breast cancers are in the over 40s. laura says if she had her time again, she might have delayed having a double mastectomy, but she has no regrets. fergus walsh, bbc news. let's return to donald trump because the president visit to britain next month is off. he had been due to attend the official opening of the new us embassy in south london. but he tweeted he was not a "big fan" of the new building. downing street says an invitation for a state visit is still open, although no date has been set. our diplomatic correspondent james landale has more. the new us embassy, on the south bank of the river thames in london. with its very own moat. a monu

following up who were all diagnosed under 40 who had brca two gene variants but he did in brca one. her coronation and describes what it is like to work her imperial state crime. here, she tells royal commentator whilst you cannot look down whilst you‘re wearing it. —— why you cannot look down. the most important items used in the coronation andy morgan‘s two crones. if the queen has only worn at saint edward‘s called crown once, she is much more familiar with this, the diamond encrusted imperial state crime. she worked at the end of her coronation and for a state openings of parliament since. —— she wore it. it is much smaller, is it not? it was the same height. you know, it would have been up to about there. when my father wore it. it was huge then? yes, very unwieldy. it is difficult to always remember that diamonds are stones, so very heavy! yes, fortunately my father and i have about the same sort of shaped head. but once you put it on, it stays. i mean, itjust remains itself. you have to keep your head very still. yes, and you cannot look down to read the speech, you have to t

the treatment was based upon their breast—cancer status rather than the brca status.8% from last week. police in north wales have confirmed that a six—month—old baby has died following a car crash with a lorry yesterday near blaenau ffestiniog in gwynedd. a passenger in the car was pronounced dead at the scene and the driver and baby were airlifted to liverpool‘s alder hey hospital — after both sustained life—threatening injuries. nigel farage has clarified remarks he made yesterday calling for a second eu referendum. the former ukip leader has said although another vote was the "last thing" he wanted, he thought it might be forced on the country by parliament. his initial remarks were seized upon by remainers, with labour‘s chuka umunna saying mr farage had made "a valid point for the first time in his life". facebook boss mark zuckerberg says the social media site will reduce clutter from the site — after criticism that there are too any adverts and promoted posts from businesses. he says he wants to prioritise what he calls ‘meaningful social interactions‘. mr zuck

women treated for breast cancer had the same survival rates, irrespective of whether they had the brcash, told me the study focussed on nearly 3,000 women at 100 hospitals in britain. it followed them for around ten years, and it found no matter what treatment they had, and whether or not they had these brca mutations. they have the same survival chances. and so a of young women, if they are carrying the faulty gene, they are generally offered the chance of having a double mastectomy, and there were fears that they were getting it young and they had this fa u lty getting it young and they had this faulty gene, that it could be a very aggressive form of breast cancer. this will give them more treatment choices because it will not be necessarily in their interests to have a double mastectomy that early in there. what is being said about prevention? completely separately from that, one in 800 women carry this faulty gene and they often find out because they have a mother, aunt ora out because they have a mother, aunt or a sister who has gone on to get breast cancer. they get tested, they

continue to have government strong start, strong finishes by increasing funding for our first class brca program by an additional $23 million. i am also proposing funding for our three through three commissioners, the alabama graduate program and for education scholarships for math and science teachers. additional dollars are investments in our children and young people and our investment in our future. education is especially effective when there is a concentration on particular subjects or skills. the alabama school of fine arts in birmingham and alabama school of mathematics and science and mobile and these are special focus schools that prepare distance for rewarding careers. evolve, wee needs must create education opportunities that prepare people to meet those needs. tonight, i am announcing the formation of the alabama school of cyber technology and engineering which will be based in huntsville. this goal will prepare some of the state's highest achieving students to edge of the growing field of cyber technology and engineering. just as huntsville has a was then on the leading edg

it finds that young women with the fault brca genes who develop breast cancer, have the same survival

for example, individuals carrying the faulty brca chants —— the faulty brca gene will have an increased%. if you know people at high risk, we can offer them options of more enhanced screening or prevention in the form of surgery to reduce the risk of ovarian cancer. to prevent breast cancer or that matter, using drugs. for preventing breast cancer. there are a range of approaches or options to reduce their cancer risk we know they are at high risk. this will prevent cancers and reduce the burden of disease in the population. thank you very much thejoining disease in the population. thank you very much the joining us from our london studio. all eyes are on the weather this morning. let's get the full update with matt. if you haven't had the snow, maybe you have had high winds and heavy rain. plenty going on this morning, some of you contending that scenes like this. very strong winds brought down trees in england and wales, but that is only part of the story. this system has brought windy weather rattling across quite quickly, and here earlier on we saw lots of snow. it is having an impa

we'll hear from someone with the brca gene. time for the latest news, here's annita.at a summit with emmanuel macron at the sandhurst military academy. heavy snowfall is continuing to cause problems in parts of scotland and northern england, with drivers warned to proceed with "extreme caution" while on the roads. although travel warnings have been downgraded, police say there is still the likelihood of disruption and delays. scottish borders council has closed all schools. severe gales are affecting other parts of the uk with fallen trees and power outages. some areas reported gusts of up to 70 miles per hour. there are calls for all women over the age of 30 to be screened for a faulty gene linked to higher rates of breast and ovarian cancer. research by the barts cancer institute in london found testing would prevent thousands of cancers and be cost—effective for the nhs. taxpayers owe private companies £199 billion for schemes set up under private finance initiatives, according to the government's spending watchdog. the national audit office found 716 deals were cu

hear every year that she had been diagnosed with breast cancer and she had a positive match for the brca 2 gene which flks the risk of -- increases the risk of developing breast cancer or ovarian cancer. jeff and sue felt powerless against this disease when they heard this. he said, quote, when you're a parent it doesn't matter how old your children are. you're supposed to slay the dragons and conquer the monsters and protect your kids. if that wasn't devastating enough, weeks later he and his wife made sure everyone in the family, in the cook family got tested. unfortunately, five other members of the family tested positive for this gene. so they're all being monitored now. here's what jeff said. we couldn't conquer the cancer but we had to do something. he said he'd heard about the american cancer society's real men wear pink campaign, a fund raising program that was held in october. october, as everybody knows it, is breast cancer awareness month. about 3,000 men across the country participated in the program this year. the real men wear pink campaign. so jeff started it. started with

since the highlighted case of angelina jolie who carries the brca gene mutation, she decided to havearry one of these brca mutations and often they have a strong family history, they have a mother, sister or art, maybe several family members who have had breast cancer as a result of these gene mutations and many of them do decide to have prevented the a double masectomy. that is not related to this study at all. there's another thing which is a limitation with this study, which was —— a very powerfully done study, but it was only young women, and many cases of breast cancer are in women above a0, and so we can't say the same findings would be in older women as well as this study so there are still questions. the devastating moment when a young woman is told and diagnosed with breast cancer and the brca gene, this effectively says you have time and you don't have to rush a decision, which is important? it is. if they are diagnosed at 20, 30, 35, they have 60, 70 years of life left, and it might be that 20-30 life left, and it might be that 20—30 years later they might be advised to ha

it finds that young women with the fault brca genes who develop breast cancer, have the same survivals as those without them. you can't look down to read a speech, you have take the speech up because if you did, your neck would break. the weight of the crown on her shoulders — the queen recalls her coronation day balancing act.