amount of gray matter in the never institutionalized -- these are children who grew up in families in bucharestromania. if you look at the children on the far left, it is dramatically reduced. they show less gray matter as do the kids in foster care. what this is showing us is the brain has much less gray matter why the function of being in an institution. we show the same reduction and white matter. what is scary about this is that it's -- we know there is a smaller brain as a function of being an institution. guest: this is so important because before chuck did these studies, people knew deprivation and a lack of parental interaction was bad for the cognitive development of children. we did not know the degree to which it affected the brain directly. this is the first evidence that shows dramatic changes in the brain. charlie: what to be different if there were some kind of activities with these kids -- much more collegiality from outside? guest: in a moment, we will talk about what happens when you put kids in families. your question is can you improve an institution? guest: and does it have