whilst bryan signed his life away to experimentation, i visit the buck, the world's first institute for ageinge working on drugs that they hope could delay age—related disease. so, here, i have two of my postdocs, margie and genesis. would you say there has been huge scientific advancement in this field recently, or is there just a sudden trend for investment and interest in it? the science has matured in terms of, you know, we've been doing this for close to 30 years, understanding the basic mechanism of ageing, number one. number two, the societal needs are there. you have a rapidly ageing population with an increasing burden of chronic diseases. this place is huge! this is one of about 20 labs! three, two, one — squeeze. it's notjust drugs and supplements being put through their paces here, though — it's also exercise. one... what kind of exercise, how much, how often? aerobics, anaerobic, lifting weight, yoga, balance, swimming — which one of these interventions actually works the best? but one really important discovery in mice here was the ability to reduce what are called senescent cell