. >> there's a codename for you, charlie foxtrot, cf. it also stands for crazy effer. ♪ >> how did you end up in silicon valley? when i graduated, i took a job in finance to relieve the immediate pressure i felt on my family. very quickly, i thought it was boring. my girlfriend at the time had moved down here. that is how i came down here. i applied for a bunch of jobs. that's how it all started. >> how did you get the job at facebook? >> i had known sean parker. >> he was president at that time? >> he said that he was going to be in washington, d.c. do you want to meet? we had a meeting and i thought this was super interesting. these guys are onto something. i did a deal with facebook. in that process, that's how i got to meet them. >> what was he like at that time? >> high potential, but still very young. >> did you know? did you have a feeling that it was going to be huge? >> i don't think we knew until about mid-2008. then we could say to ourselves, there is a formula here. by formula i mean that we understood the psychology of why p

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update on that we heard an update on the scorecard how it's being put together with the lack of the cf t data that was a big point of discussion what we're using to put that together that will be coming to the full board we'll have a discussion about the balanced scorecard so if the committee members have anything to add. >> commissioner norton and yes. i wanted to say we're not having a budgeted meeting the budget was released and mayor ed lee are analyzing that and we'll have the next budget in the governance committee will be wednesday on february 4th and the student assignment committee will be thursday, february 5th at 6:00 p.m. i have a very busy week. >> reports by other board members. >> any announcements commissioner mendoza-mcdonnell. >> thank you with the support of quite a few of the community members businesses in san francisco we want to replicate the forecasts happening in new york and chicago we've organized the viewing of selma a movie about any member of the public wish to speak on this item for our 7th, 8th and 9th for 10 thousand students for free and so the fund th

we estimate around 13% and cf around 10%., 60 to 80% of the patients. >> how do people know if they have that mutation? >> they have to go and get identified and sequence their dna to confirm it is a mutation -- >> could we do that five years ago? >> it's getting faster and cheaper to do it for the patients. >> one of the things i notice was and this is sad stuff -- everything you treat is very sad there's one if you get to people who are between 5 and 6 years old you might be able to save their lives. later on you can't. >> you want to treat the boys -- >> it's boys right? >> yeah it's predominantly boys because it's an x linked genetic disorder and lies on the x chromosome. >> if they don't have it -- i was trying to figure out all of the research could be worth $1 billion. if they -- they have to be treated for many years and then ultimately they do die. a health care -- health maintenance organization would have to pay millions over time to take care of these people unless these people are identified and take your drug. >

in sioux city, cf industries will be expanding production of nitrogen fertilizer for iowa's farmers. the iowa fertilizer plant under construction in lee county will produce both nitrogen fertilizer and def to reduce pollution and increase mileage for diesel engines. valent biosciences, kinze, kemin, sabre, brownell's, and midamerican's historic wind project are all growing right here in iowa. across our state, though farming operations still provide the lifeblood of our economy. this continued success depends on their ability to connect. not only in connecting their equipment to the ground, but in this day and age it also means connecting their equipment to the internet. connecting with the global marketplace to sell their goods. connecting to main streets across iowa. the fabric of our state is woven together by the gravel roads and interstate highways, but in this day and age it also must be connected through access to broadband as well. this legislative session, let's come together and pass legislation allowing rural iowa to experience continued growth and connection to the rest o

it describes how they were devastated, in tears, but swept along by a cf solidarity. they reported from the pavement and the balconies in paris. >> how are the events yesterday in paris being reported overseas? >> "the guardian" talks about a nation united against terror. not only france, but europe, too, needs to overcome barbarism and xenophobia. but the heads of state -- at appears to be the only bone of contention with yesterday's event. many people are questioning the legitimacy of some of the heads of state to actually be there at a rally for press freedom and freedom of speech. in particular, ministers from egypt and turkey, both countries who have been carrying out crackdowns on journalists, most recently and the jailing of al jazeera journalists in egypt. >> what about international paper's? >> "the wall street journal" has no mention of the fact that there was a high profile absentee from yesterday's and events, and that of course is barack obama, the u.s. president. it was quite an obvious gap in what was a real collection in heads of state -- i think it wa

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alliance and at the upcoming conference of mayors in dc in january they will be doing a piece on lwc cf to further advocacy at the local level with the funding. the secretary was invited to be the keynote speaker at our upcoming parks conference which is around the corner. this is the city parks alliance is national conference -- international conference, greener and greener and vibrant cities and held here in san francisco between april 11 and 14 2015. greater and greener will bring thght a thousand leaders from around the world to celebrate, and connect and improve the economy and the environment around the world. you will hear more about that in the new year and this commission i am hoping is present and an active participant in the gala and the panels throughout the week but we're excited to welcome the world in san francisco in april and we have invited the secretary to be our keynote speaker. so more on that to come. winter registration. if you weren't paying attention last week get ready for winter. registration for the popular winter programs began with hundreds of classes aroun

tell us about how many patients you can treat with these drugs. >> we're really on a journey with cf patients. today our medicines are approved for 3,000 patients around the world out of a total of 75,000. what we're really excited about is we expect to get approval for our next combination of medicines and that will allow us to expand from 3,000 to as many as 25,000 over the next year. >> big question people have for you and you don't have approval yet but upon approval which i think is expected is pricing. and with orphan drugs you can often price $300,000. i think some people expect that the combination you have that could potentially come late they are year could be less than that. can you give us any guidguidance? >> it's way too early to talk about pricing. we haven't even seen the label we're going to get or the approval. we are focused on getting the approval on time so we can get this medication to patients and making sure every patient who needs the medicine will have access to it. >> this is a big business development conference as well as making presentation to your inves

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golden gate bridge and smooth and steady southbound from free and on the richmond braves the back of cf for the westbound ride it will also under assault advisory along with your life ride across the cortines bridge under a fall in advisory this morning about there's been no accidents on 80 there was a crash tear eastbound on highway 4 slow the ride little but interstate 80 was bought by times are really not too bad. still under 20 minutes 680 soph from dublin leading down to some of some of the freeway still looks great will not tracking any major problems get. >>george: on 92 of the skyline because of a stalled bid rate there. >>darya: bay area news this morning of the call of marijuana plants have been found since cisco's bayview hundred and 60 plans receives less like an apartment on bidding avenue police said the party was being used illegally growth marijuana the propman's found out about the growth after she was unable to get ahold of the elderly tenants for several months the plants were surrounded by lighting ventilation and other hydroponic equipment. >>mark: suspected bomb th

. >> i want people to know about cf and organ donation, that's it, i don't want money or anything, iawareness, i want lives to be saved. channel 7 eyewitness news perdue. we believe in a better chicken. latte or au lait? cozy or cool? exactly the way you want it... until boom, it's bedtime! your mattress is a battleground of thwarted desire. enter the sleep number bed. save $300 on the final close-out of the c3 queen mattress set. he's the softy. his sleep number setting is 35. you're the rock, at 60. and snoring? sleep number's even got an adjustment for that. only at a sleep number store. right now find the lowest prices of the season, plus 36 month financing on qualifying purchases. hurry ends monday! know better sleep with sleep number. imported chicken's been in the news a lot lately. for chicken that hasn't crossed an ocean look for perdue. we're the first company to have the usda verify that our chickens are raised in the usa. to bring your family a fresh-tasting chicken. perdue. we believe in a better chicken. >> president obama is making it clear that is state of the union t

some cfs patients say it brought them no about the benefit.b tç focusing on the positive could be goodart. a large study suggested optimistic people have a leg up when it comes to cardiovascular health. and when some people try to look intelligent, they do things that may actually make them look dumb. so the "wall street journal" took a look at what actually works and found glasses do work. the fancy words don't. and the biggest way to appear smart, look someone in the eye when you're having a conversation with them. i am jane king. >> i was going to say glasses. >> me, too. that was the first thing. >> thinking about getting glasses, whether i need them or not. it's just going to help. >> drew is here. he's checking on our forecaster, not wearing glasses. >> i'm not. >> could be a big mistake. >> what does that mean if i don't wear glasses? >> don't read anything into it. >> not at all. >> we have yesterday yet to see measurable precipitation in downtown forecast this month and typically this is one of our wettest months of the year. we'll see partly cloudy skies and those clouds are

into contact with another substance when t is an issue with the insuteorinsulator, is not uncommon see#cfsmoke or spark. that appears b situation r t o track. now single tracking between boston clarendon declays 20 to 30 minutes on both lines as firefighters lo at the situation. maintenance crues looking to make sure it's not a lingering proble with further effects. initially we saw a lot more firefighters. nowust one fire truck but we are in contact with the fire department and will keep you posted as we get more information touthe hour. >> thanks, richard. >>> traffic is getting back to normal, but crews are still cleaning up afterñp a water main break wraeked havoc during rush hour. megan mcgrath joins us live from the scene to tell us how repairs are going. good morning. >> reporter: mn barbara. just within the last 15 minutes or so they actually started to dig down there, trying to get down to the pipe to see what kind of a break they have. this is center park drive. you can see the gaping hole. we'll told it's going to take anywhere from six to eight hours to fix this broken water m

. >> cf industries trading 2.90, i think it gets to 300, that 9 versus 10. >> all right, josh, i guesse going to resume this debate over google. >> not really a debate. i don't know that there's a near-term catalyst. i think the stock is chief up in to buy, hold on it. i think this could be a company that blossoms for 100 years. i don't need a catalyst tomorrow. >> 100 years. >> five below, f-i-v-e. >> that's the rating on your dance moves. >> unfortunately, that's what i got on "dancing with the stars" last night. no, this one, strong upside activity, judge, bought it today. >> and how about you, pete? >> i'm looking at these chemical names and the way they've been reacting and the huge move over the last couple days. dupont getting towards those 52-week highs. we had activity. i think it's going higher. >> what has more truth to it, the first five day that were pretty ugly in this market or what could be another pretty strong day to the upside for stocks? >> how about tomorrow's jobs report, so none of that matters. i think tomorrow's jobs report. >> reset the board. >> new world, ne

. >> joe, what's going on -- >> let's talk about cf based on nitrog nitrogen, lower gas prices.thought it would get to 300. it's gotten there. the time has come to reallocate the trade. last night mosaic's earnings were fantastic. phosphate business real strong. potash business looks strong as well. potash i like those two names. mosaic on the goldman sachs sell list. i think that's wrong. >> unusual activity. >> let's do it. >> a retailer. >> that's right. >> apparel name. >> men's warehouse. take a look at this one, folks. what they did, this is a trader, i don't know who it is, i just see the footprints but the guy gets in there and sells a lot of puts and then buys you upside calls. that's what they did in men's warehouse, judge. it's out in january of next year, a long term trade and bought them in real big numbers like i say, a trader that's done this frequently. >> are you in it? >> i'm in these calls. >> in the calls as well. >> how long will you hold them? >> i think a couple weeks because i'm a twitchy trader. this is a long-term trade whoever put this on because janua

ha cantgus, wlmt or eh cf es ommcesna fig oow fu a paforapoatyte vell were gin finrsve ba isaple cog maon tram ju taedbo wl leon t b as onges th o. its y tknothe pridt ang coitntoin ct d r psa ae inasucreecd t adesthwaclf a opos aldo gr era ac paf attheact ulddo ulactlly case he tralanorti pgr cowchs a 0 li tayr hefour tth program wod be 38 illio we would also do morenvestments to ensure that we were building broadband in rural areas for example using the opportunity when we build roads to did want to get fiber optic laid out in rural communities so folks can have access to the 21st century economy. [applause] so which tha w want e rof tolio pt t wapee elane cnne t te ery wibey msias las i'seety tanorti toakth thceodi cotr thk u ermuc encee weks back to defy bipartisan opposition bipartisan opposition to what happened in novem by changing the rules that govern this place with a simple majority, she broke something. he broke something. but our response can't be to sit back and accept the demise of the senate. this body has survived mistakes and excesses before and even after some of i

there's a mission in the military cf to tell to tell me more precisely what the mission is and i can tell you what it takes to do it and that gets decided in the new go and you are successful and you have to be careful that the mission doesn't changed. it's something you didn't provide for to begin with. >> thank you very much. my time is ended. i don't know dr. kissinger if you have anything you wanted to add to that. >> there are two aspects. it's the organization adequate to give an opportunity to express itself but the second challenge we have faced in defining a national strategy is that in our national experience we have had a different experience than most other nations. we have been secured so for americans security presented itself as a series of individual issues for which there could be a pragmatic solution after which there was no need for further engagement until the next crisis came along. but for most nations and for us now more than ever the need is for a continuing concept of national strategy. we think foreign policies is a series of pragmatic issues. other countrie

partnering with government agencies, with medical groups, with ra0uc&Ñ specialty groups, et cetera,.çf-opted by them.k #+âáq re very few -- there are very few consumer advocacy groups that don't take money from pharma.tq there are fewer than ten national groups in the united states that do not take money from pharmaceutical companies.r9ñ#hctqgaezuhp &hc% for individual physicians, the réx f shift has been away from cash, and towards more services.u we'll do a website for you.we we'll provide web pads that your jjents can fill out their information, their medical history on so that somebody doesn't have to transcribe that.uqf]ñ that information actually gets sent back to pharmaceutical companies. it's deconfidentialized first.r but it's a way for them to collect all this information, in medical records are also sold to pharmaceutical companies.lbzi those records,?a so it's anonmized patient ym+el data, but pharmaceutical companies know everything about your health history. your you went to a doctor, your zip code you live in your body mass index. as long as they don't know your name, th

. >> i do think that when we were in cf and ukraine, generally together, i think we understand as together we met with the leadership, the importance of americans support the -- kiev -- for what they are doing there. and nato in the baltics i agree with dr. brzezinski. i think that it's important for the baltic countries are members of nato and i think it is very important to show that kind of support. the question is whether they're kind of rotating troops or their permanently by do think the united states needs to be a part of a grouping, which also requires other countries from nato to be there. i know dr. brzezinski spoke about the importance of germans the brits, et cetera also think about you think that it is an important aspect of our common approach to this through nato. i also do think that nato is at a stage where it has to come we were talking about organizations that have been started many years ago, that our support for nato in getting the other nato countries to pay up what they are obligated to do under the 2% of the gdp for activities, i think as i've understood the new sec

example, is çúvq going to attack the structural deficit, we're going toç dÑ reform entitlements. 7cfg8hx xlvdegj reported. i think nina is exactly <6kÑrig. this is barack obama 2.0, 6.0. there's not going to be any change here.> >> is this president going to ññ on the issue of trade? i mean, justdu('Ñ looking at th app pretty stark. thisd oi is a democratic presid >> you can see that he says in know, i understandb unraveled and not gone well, that's why we're going to do this differently. he's making an early pitch to democrats here. i think if you notice, by just the response that you are pointing out, bret, this is not something that plays well with the unions that are key fund-raisers for the democratic party. this is going to be his struggle with his own party. and he's got to be careful here with republicans now in the majority, in both the house and the senate. about which democrats are peeled off by senate majority leader mcconnell, and even speaker boehner, although that's less likely. but you've got red state democrats up in '16 that are a real threat to the obama agenda goi

when a border patrol agent involvendìáhp &hc% so t,cf publich z0 by)ax patrol can either be held accountablee'll give you a business card and point of cop the act if there's a specific oñ!.3"q about the checkpoint over the past we're i want to know how many<7 apprehensions were made p r(t&háhp &hc% t&9(checkpoint whatever the inquiry is and to the extent we can do that, whatever the question is if we're abletÑhz to it. fair vafjenough? thank you.@vá >> anyone i'm sorry. ma'am.da2, >> my name is jeanette horton. i'm from the australia jan embassy here in washington, d.c. i have a technical questionfm about your and how you use them in calculating this border flow particularly how do you measure what you&ç8 don't know? for those:l#ñ where you haven't aprehenned someone, they are not aé those 6z into your risk.,c' metric?@zn÷ñ >> that's a great point. that's the question even when i first tame up in 2010. i heard it repeatedly. so if a=zéq tree falls in the forest and there's nobody around does it make a sound? right. so how do you know what:f you don't know. you're giving us -- inn-q$4ñ still

going on like that, that areÑwjo criminal or wrong or against our constitution i'm pretty this stage,+cfme at 7:00kilx in the morning.z y get tojÑ,?ñ the office at 8:00."uycf >> youífÑ got a white house car?lnt >> you got a white house car? >>go)m!r ÷g >> i'mbu,:s going to ask the next e5"3x question. >>áú@ a6)e. cut a better dealca than%kiÑ we did. [ laughtert"& ] >>"h)lñ soy i leave"y6hhome ato get to the white house at 8:00. east breakfast there. [ ánf-ñlaughter ] >> what do you think we're going to get23jiwould farm out to get:h3ñ the answers, ande z i would have a meeting with the president at->f f 10:00, and my briefing would beu0h at 11:00. then this the afternoon0nj reporters would wander in and out of"áqt myz]ilñ office with their ownr questions, you know, and there were meetings that i attended and so .c&éy and i would 8:00. and i and he would be asleep by the time im sÑ w5. x)ñ been asleep in i left and asleep and i would wake him because that's the only time itr would get to see him so you know, that's alrb2Ñ long day. but that was >> about yiqrví[ car -- >> we want to know a

. >> a pilot is practicing a tricky maneuver in his cf-18 fighter jet. >> doing something called an alpha a really risky maneuver. he is doing it at low altitudes so everybody can see it. >> the jet malfunctions and plummets to the ground. >> the jet goes boom, massive explosion. >> but just 100 feet before impact, the pilot ejects from the plane. >> you can actually see it happen, that split second between life and death. >> he suffers a few compressed vertebrae but is alive. days later the brave pilot brian hughes describes his wild ride on "today." >> it became obvious what i needed to do. i was well trained for it. it was just a matter of pulling the handle and going for a ride. >>> coming up, can you say ouch? that's got to hurt. find out which of these five videos made us cringe the most when "extreme caught on camera: the 100th episode" continues. with the incredible fuel efficiency of 38 miles-per-gallon highway, you can feel like royalty in the nissan altima. now, get great offers on the 38 mpg highway nissan altima. nissan innovation that excites. how can in china,sumption impac

in sioux city cf industries will be expanding production of nitrogen fertilizer for iowa farmers. the iowa fertilizer plant under construction in lee county will produce both nitrogen fertilizer and d.e.f. to reduce pollution and increase mileage for diesel engines. valent biosciences, kenzie, kamen, saber, brownells and mid americas historic wind project are all growing right here in iowa. across our state though farming operations still provide the lifeblood of our economy this continued success depends and their continued success depends on their ability to connect. not only to connect their equipment to the ground but in this day and age it means connecting their equipment to the internet. connecting with a global marketplace to sell their goods, connecting to main streets across iowa. the fabric of our state is woven together by the gravel roads and interstate highways. in this day and age it must also be connected by access to broadband as well. this legislative session let's come together and pass legislation allowing rural iowa to experience continued growth and connection

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