charlene is with us in louisiana. hey, charlene, go ahead. >> caller: how are you doing, mike? thank you for taking my call. >> yeah. >> caller: i'm from a family of eight. my mother had five daughters. they say that it's not hereditary. my grandmother had her breasts removed. my great-aunt had had breasts removed. my mother's doctor said, if you have daughters, which she told us she had five, make sure they get their yearly mammograms. and they want -- i have sisters, i'm 58 years old, but i have sisters that are younger than me. what are we supposed to do? >> charlene is actually someone who should talk to her doctor about the bracket gene. that's the genetic component to breast cancer. the doctor can speak to this more. when you have breast cancer, level after level after level, you might be concerned about a family gene in there that is -- makes you predisposed to breast cancer. >> dr. carl d'orsi, can you speak to that? >> hi from louisiana. i understand what you're saying. and interestingly, to get to your point, most of the cancers that are discovered are not in high-ris