funding for charlie rose was provided by the following. durable funding provided by these funders. >> and by bloomberg, a provider of multimedia news and information services worldwide. captioning sponsored by rose communications from our studios in new york city, this is charlie rose. rose. >> tonight we will continue our study of the human brain, examining one of the most widespread disorder, depression. depression describes a group of conditions characterized by significant and sustained periods of low mood, symptoms can include persistent sad, anxious or empty feelings, fatigue, appetite loss and thoughts of suicide, or suicide attempts. approximately five to seven percent of the adult population of the united states will suffer from a form of depression during any year. the lifetime risk may six seed 15 percent. >> our understanding of depression has evolved over the centuries, hippocrates believed the mel commonly as it was known was caused by an excess of black bile in the spleen, during the age of enlightenment depression was believ

>> physical exercise and intellectual, running at charlie rose, if you ever thought of taking up a program the morning that would probably enhance your cognitive capability. have you ever thought of that? >> rose: i appreciate the argument, though, very much. okay so let me understand. this is all enormously exciting to me because suppose we had a way of increasing the amount of stuff we can load into our unconscious. >> well there is some research that shows that distracting consciousness actually enhances nonconscious processing. >> rose: ah. >> experiments where you give people a problem, they have a bunch of stimula, to evaluate new car to see which one is the best, and then you either ask them to think about it as much as they want or you distract them and give them something very absorbing to do where they can't think about gliet and what happens? >> it is the people who are distracted who make the best choice. >> rose: and why is that? >> well, the idea is that by consciousness can intrude and get in the way of unconscious processing. >> rose: consciousness focuses on one or two poi

tonight a special edition of the charlie rose b brain series year two. and our fifth episode we focused on schizophrenia. >> we're going speak about the most devastating of all psychiatric illnesses, schizophrenia. but now as you learn we are really beginning to understand the beginnings of a scientific bases of schizophrenia. we have danny hurley here who can tell us what it is like to actually experience the disease. >> rose: episode 5 of the charlie rose brain series 2, underwritten by the siemons foundation. coming up, about the most exciting scientific journey of our time. >> understanding the brain. the series is made possible by a grant from the siemons foundation. their mission is to advance the frontiers of research in the basic sciences and mathematics. >> funding for charlie rose was provided by the following: captioning sponsored by rose communications from our studios in new york city, this is charlie rose. >> tonight we continue our study of the human brain, examining one of its most devastating diseases, schizophrenia. schizophrenia is a c

captioning sponsored by rose communications from our studios in new york city, this is charlie rose. >> rose: tonight, we. our exploration into our magnificent brain with a look at disorders of movement. they're associated with changes in the brain cells that help us move. these changes can affect the speed, quality, and ease of movement. the two disorders we will focus on are parkinson's disease, and huntington's disease. parkinson's disease was first described in 1817 by the british physician, james parkinson. approximately one million people in the united states alone are afflicted. parkinson's' onset is typically subtle and commonly developed between 55 and 85. its features include tremors, difficulty moving, slowness of moving and muscular stiffness. it results when cells in the part of the brain that produce dopamine fail and deteriorate. there is currently no cure for parkinson's disease. huntington's is more complex than parkinson's. it is a hereditary nur lodgal disorder first described by james huntington. those affiliated typically see the signs in early middle age. the sym

funding for charlie rose was provided by the following. >> rose: additional funding provided by these funders. and by bloomberg, a provider of multimedia news and information services worldwide. captioning sponsored by rose communications from our studios in new york city, this is charlie rose. >> rose: the drawdown in afghanistan is gathering pace as nato troops plan to shift from a combat role to a supporting role by 2014, the question is, what comes next? joining me now, stephen hadley, who serves as national security advisor for george w. bush and john podesta, bill clinton's chief of staff from 1998 until 2001, and 2011, they chaired a bipartisan committee to review policy towards afghanistan and pakista they have published their findings as an essay in foreign affairs magazine, under the title the right way out of afghanistan, i am pleased to have them both at this table. welcome. >> good to have you here. this is important work. so tell me what your marching orders were to yourself, how you wanted to accomplish that objective. >> well, we wanted to have a broad gauge group of p

funding for charlie rose was provided by the following. >> rose: additional funding provided by these funders. and by bloomberg, a provider of multimedia news and information services worldwide. captioning sponsored by rose communications from our studios in new york city, this is charlie rose. >> rose: the drawdown in afghanistan is gathering pace as nato troops plan to shift from a combat role to a supporting role by 2014, the question is, what comes next? joining me now, stephen hadley, who serves as national security advisor for george w. bush and john podesta, bill clinton's chief of staff from 1998 until 2001, and 2011, they chaired a bipartisan committee to review policy towards afghanistan and pakistan, they have published their findings as an essay in foreign affairs magazine, under the title the right way out of afghanistan, i am pleased to have them both at this table. welcome. >> good to have you here. this is important work. so tell me what your marching orders were to yourself, how you wanted to accomplish that objective. >> well, we wanted to have a broad gauge group of

>> got it going out, charlie. >> rose: it's a hard question. >> it's a very hard question for me because i do think in terms of things that float my boat. i love being with inventors. >> rose: right. >> and innovators and people trying to change the world and leverage technologies to do good things. and i, that does probably resonate more with romney than it does with barack obama. i think other things are important -- >> that's central to his argument. >> yeah, but at the same time, you know, what bothered me here last night, it's all related. so they had the "we built it," playing off on obama's statement -- >> "they didn't build it. >> was he was talking about horizon, roads and infrastructure -- >> which is essential for entrepreneurs to have. >> i give obama credit for that. his investment in innovation, in technology. we're one day after-- barack obama will never takeab ad out on this and i think i'm the only columnanist this hemisphere who wrote a column about it, but barack obama put in place new mileage standards that were required by the 20ed 25, the doubling, basically, of mil

tonight a special edition, the charlie rose brain series, year two, and a third episode we focus on, they are selective deficiencies in consciousness or con i cognition. >> i was trying to understand the aphasias and commit them to memory of those i know and love and for me, it has to be flattened out, once it is flattened out, i can commit it to memory in a way i can't if i am looking at you, if you move your head half an inch, it is a whole new head i haven't seen. >> rose:. >> it is confusing fund forget charlie rose was provided by the following. pro pro ago in it they coined a term agnosia, by that he meant that people in a variety of spheres have difficulty knowing exactly what the object is. it is a deficiency in knowledge. so for example, a person with visual agnosia may look at this cup, see that it is white, see that it is round, see that it sits flat, they would not realize it is a cup for drinking. this amazing insight that you can have a selective defect in knowledge, agnosia, has stayed with us to the present time. more over, what pleased freud even more than realizing

. >> jan, charlie rose, good morning. >> welcome back, charlie. >> thank you. the romney campaign clearly must be beyond distraction, that it brings social issues to the front because the congressman is making that the reason for his defiance. >> reporter: that's exactly right and you're seeing the democrats try to use that, make this an issue and tie the republicans to todd akin. you have the party you nighted in lockstep. we're in a factory, so if you hear the background noise, romney has an event later today. the republicans are saying no, you nighted in lockstep and not just the establishment. akin last night was tweeting that the liberal elite, the liberal media is out to get him, this is the conservative media, people like limbaugh, hanity, ann coulter saying he needs to go. he is a man without a country now. >> rick david manager of john mccain's 2008 run. >> good morning. >> what can he do? >> keep the heat on, he's doing exactly the right thing as the leader of our party. the point is that he is the leader of our party. they've had ryan call him up and

>> everything is or sale, charlie. >> rose: okay. just name the price. >> you have to name the price. i shouldn't say that actually because you could think about group upon, group o n turned down $10 billion for their company. >> rose: they regret that? >> i don't think they admit they would regret that. >> i think the market value is four, 5 billion and it kowk could be a longer term play. my skepticism of the groupon model, i am not convinced. >> rose: and they offered 6 billion. >> 6 billion from larry page and sergei -- >> rose: i tell you one good investment made is youtube. >> fantastic and by the way a business that was make nothing money at the time. >> rose: exactly. >> and they figured it out, absolutely, and by the way that is a little bit of the way apple i think has to think about some of these investments. meaning you are going to take some of the -- >> rose: it may not be today -- >> right. it may not pay today but down the line and you have to suffer through by the way which was a lot of criticism and skepticism of tha