peter knoll was not interested in chromosomes. at that point there was very little knowledge, no knowledge about the connection between genetics and cancer. no one was looking for the cause of cancer in our genes. he figured someone would be interested in this and as it turned out, that someone was david underford, in philadelphia, he was this very old school scientists, loved to look through the microscope day after day, he was not trying to cure cancer. he was not really trying to do anything but what he loved which was to observe so he started working with peter noel and looking at chromosomes through the microscope and one day was looking at some cells from a patient with cmo and noticed one of the chromosomes was a bit too short. he was one of a handful of people probably in the country if not the world who could have spotted this at that time and what he saw is on the cover of the book. but it was this. chromosome 22, the cell sample, was a bit too small. they didn't know what to make of it at the time and there wasn't any t

down's syndrome just so you know, it's an extra chromosome 21. we all have 46 chromosomes. down's syndrome children have 47. we all know the signs and symptoms. the cognitive disability that comes with it. beautiful children that grow to be in their mid-adults. medical conditions from heart to thyroid to weight gain that comes with this. exciting research from umass, dr. gene lawrence who's taken it to a whole new level. that's the exciting part. for the last two decades we've talked about gene mapping. we're sequencing the genes. all the letters you see in the gene. now we're talking about really genetic editing which is unbelievable. we are basically cut and paste like the way you do on your computer with paragraphs. now we're starting to do that. this particular study is something call eed chromosomeal therapy. what does it mean? she has been able to insert a gene calmed xist. it's going to create some r and a and shut down that extra chrome some 21. which is incredible. while this is research, it opens the door to a lot of other research in down syndrome and many other

>> just go to chromosomes are us and get yourselves new chromosome chromosome chromosomes, preferably ponies and glitter. >> stephanie: right. we'll have to play that again for the ecclesiastical mook. >> stephanie: all right. >> we know what is going on in this thought bubble. the kids don't know but we do. >> announcer: it's the "stephanie miller show." ♪ (vo) current tv is the place for true stories. (vo) with award winning documentaries that take you inside the headlines. real, gripping, current. documentaries. ♪ >> announcer: stephanie miller. ♪ i'm a bitch, i'm a lover i'm a child, i'm a mother i'm a sinner, i'm a saint, i'm your help, i'm your dream, i'm nothing in between, you know you wouldn't want it any other way ♪ >> you are mean. >> stephanie: jim was doing alternative lyrics. >> she is a bitch. and that's why her career is nowhere. >> stephanie: oh, by the way, because we start everything important here on the "stephanie miller show," all day trending on twitter was a shark-nado. three sharks were thrown on to land by a tornado. and he deals with it how -- >> with a seri

though rare, there are other causes of hypgonadism that are chromosomal in nature.n boys, it's called klinefelter syndrome, where a problem exists within the chromosomes themselves, causing an extreme delay in puberty. still, other causes of hypgonadism can be directly related to medical issues. >> when i was 26 years old, i was diagnosed with testicular lymphoma. as a result of the lymphoma, i was required to undergo chemotherapy and radiation. >> mcfarland: mark botelho is now 34 and lives in fall river, massachusetts, with his wife, melissa. as is the case with a few other types of cancer treatments, mark's therapies didn't just create a temporary drop in testosterone; they created a permanent one. >> it lowered my testosterone levels. my levels tended to slowly taper off over time. and i was tired. i was frequently tired. i didn't really want to do much. >> i cried a few times, and then--but it was like, all right. him seeing me like that made it worse for him, so i just kind of... you know, i got strong about it. >> i worried a lot about the future, specificall

stanwood first, there are some genetic conditions, chromosomal an 94 mabnormalitie cannot be detected until after 22 weeks. first of all, is that common, and what would happen in a situation if these restrictions are in place? >> i think that's a very concerning point that you bring up, in that a large part of my practice when i have patients referred to me for second trimester abortions has to do with desired pregnancies where they've gotten terrible news. most ultrasounds that are done to detect abnormal fetal anatomy are done at about 20 weeks gestation, patients thought they had a normal pregnancy and they got devastating news and part of the concern with these restrictions is sometimes the news that they get is preliminary, they need a second opinion, they need to see additional experts, they need to have testing maybe like chromosomal testing like an amnio-senn see tis and to have an arbitrarily restriction on the process robs the patients of the time and dignity they need to come to grips to the situation and make the best decisions for themselves and their families. >> represe

chromosome 3, chromosome 8, about where on the dna molecule that they are located. locations that i test. >> all right. tell me the significance of this one right here. that i'm circling. >> the amelojenin location is in addition to the 13 location. it's a sex determining location. it gives me an indication of whether or not that individual has two x chromosomes, which would make them a female, or an x and a y chromosome, which would make them a male. >> okay. if you could move to that middle column. that's titled jr-20. jr is the number i'm assuming that was designated by fdle or by the submitting agency? >> yes. that's the exhibit number. exhibit jr-2. that was from sanford police department. >> okay. under that column right there, you have it appears on each one of the -- on each column two numbers. tell me the significance of that, if you could. >> these numbers here, this -- if you read down, this is the dna profile for george zimmerman. these numbers represent different size fragments of dna that are found at that location. so that's my result at that location

. >> the cast of the double x chromosome project. >> reporter: are you guys ready? >> [screams] >> reporter: take it to the bank when eyewitness news continues. ,,,,,, i'm drinking dunkin'. i'm drinking dunkin' iced mocha. they make it exactly how i like it. medium, iced, with a turbo shot. french vanilla, hazelnut, caramel -- i love 'em all. they make it perfect every time. >>> nationwide demonstrators continue to protest the acquittal of george zimmerman. hundreds of people staged the sit in. zimmerman was acquitted all charges in the shooting death of trayvon martin. he was acquitted on saturday night. >>> 16 minutes past the hour. marylanders -- marty is over at first warning weather. >> the air is close this morning. the barometer is at 30.30. we told you that high was getting a second wind and expanding. friday the barometer was 29.97. now it's at 30.30. that's the driving force of your weather all weekend long. 63 oakland, 66 cumberland, 74 elkton, 73 easton, the low 70s ocean city, pax river, hagerstown, 76 in the district, the mid 70s annapolis, kent island

. >> reporter: they research chromosomes in the rice cells and analyze the dna. they were able to diagnose each gene. they were able to determine which gene resists disease, tolerate heat or cold as well as which genes result in the growth of larger grains. they crossbreed delicious rice with other varieties that carry the desired qualities and by analyzing the genes they select only suppose specimens that have the best characteristics. this method ensures quick and precise gene selection. and it also saves time. this technique is called genome breeding. >> translator: the breeding used to take ten years, but now it's possible to cut that time in half or even a third. japan's agricultural industry will find this helpful. >> reporter: japan has a big incentive to promote the genome breeding project. the amount of rice exports around the world has tripled since 1990. to compete in the global market, japanese officials set a goal this year of lowering the cost of rice production by 40%, and it started developing new kinds in earnest. >> translator: our biggest goal

researchers have essentially turned off the extra copy of chromosome 21 in stem cells which causes down's syndrome. scientists say this could lead to treatments for conditions related to down's including weakened muscles and heart disease. >> a texas abortion bill blocked by a filibuster last month will be signed into law today. the governor will sign the measure this morning mandating that abortions only be performed at subject california centers by doctor would have hospital admitting privileges. only five of the 42 abortion clinics meet the new requirements. >> the mayor in new york is taking aim at elevators and wants workers to take the stairs instead, a bill he is proposing requires all buildings undergoing major renovation to give occupants access to one stairwell. he has waged war on cigarettes, trans-fats and super sized drinks. >> a message from the san francisco public utilities commission: don't flush the wipes down the toilet. some are advertised as flushable, they aren't. officials say they clog sewer systems and in san francisco officials say it is an expensive problem to c

>> if a fetus, a normal, genetically chromosomally normal fetus is exposed to a tiny bit of plutonium that lodges in its brain, developing brain, it can kill the cell that's gonna form the right half of the brain or the left arm. that's called teratogenesis, damage of a normal fetus, and that's what that drug thalidomide did when women took it for morning sickness and their babies were born with no arms or no legs. it does that. it also--plutonium in particular, which is highly mutagenic--lodges in the testicles. so it has a predilection for testicles, and it lodges next to the spermatogonia, the cells that form the sperm, the precursors, and it's an alpha emitter, highly mutagenic. so it can mutate genes in the sperm to induce genetic mutations and genetic disease down the generations. now, there are two sorts of mutations, dominant-- so if you have a baby with a dominant mutation like brown eyes, the baby will have brown eyes, or dwarfism-- achondroplastic dwarfism is dominant--but most mutations are recessive like blue eyes. you have to have two genes to have blue eyes. because if

give transgender students the right to choose their restrooms, and teams, based on identity than chromosomes> a higher intake of fish oil would lead to a reduction of breast cancer risk later in life. nutritionists recommend one or two servings a week of oily fish, like tuna, salmon or sardines. >>> james gandolfini's 13-year-old son is getting the lion's share of his estate. he will also give a fortune of chunk to that 8-year-old daughter. the rest of the estate will be divided up among the actor's wife and sisters. >>> what started out as an engagement photo session in a philadelphia park, turned into a life-saving rescue, as this couple had the perfect pose, a little boy stepped off the rocks and into the water. the fully-clothed bride-to-be, dove into the water to get him out. the bride-to-be, her fiancee and the photographer are emts. >>> after a car and cell phone were taken at gun point, she logged into her account. she dialed one of them, learned the suspect's whereabouts and turned things over to police. >> the cops followed the car, pulled him over. and they just took off. they mad

can ake ivf much more affordable, because the technique helps pick high fertility embryos without chromosomalabnormalities. that makes implementation more likely and costs less than the current screening tests. right now, ivf costs and thousand dollars for one single try. and with kids that came to the emergency room with an isolated head injury, it was then that most parents did not know that the radiation exposure from the ct scan was higher than for a regular x-ray and as an increased risk for problems. and as we all know, your metabolism slows down as you age, but there are ways to boost your metabolism. in the middle of bathing suit season, we have more. >> times for shorts and swimsuits, but if you want to feel more secure wearing less, you need to rev up your metabolism. >> there are several ways of doing it. my favorite, of course, is exercise. the food youburnt are taking. >> and if you add weight training to your exercise routine, an additional 5 to 10 pounds of lean muscle mass can burn an additional 100 calories per day. tip no. two, you should eat a small meal every two hours, wh

> governor huckabee: even if there was, once the baby ask developing once 23 male and 23 female chromosomesnd life is started and it is life. it's separate from the mother because it doesn't have her d.n.a. schedule why don't we at least do everything possible to protect that life as a testament to our understanding that every life has value and worth? i would answer that question if it weren't for the fact that what's happening in texas which you support, you were down there. >> governor huckabee: yeah, i was. >> you were rallying. absol utely. >> is going to result in more late term abortions. >> governor huckabee: you say if we allow more abortions we have less abortions? >> no. what i'm saying is if you eliminate providers and you say we are going to take away 8 providers in this state and just leave five and all the women who would normally be served by those have to now rely on fewer, what that causes is delay. and in pregnancy delay happens very quickly, a week, two weeks, and also gets very expensive. so, now you are snow balling. now what was $500 procedure becomes $1,000 procedure

a gene responsible for down's syndrome turning off the extra copy of the kremlin season -- the chromosome that causes the problems including heart disease and weakened muscles. >> former governor of arizona, former secretary of homeland security, and now janet napolitano is hours away from becoming the u.c. president and we will preview the vote at the u.c. board of regents meeting. >> a quadruple shooting in oakland leaves an 8-year-old girl dead. >> live from the kgo-tv broadcast center this is abc7 news. >> we have breaks news from oakland where a young girl is left for dead and three are injureed. abc7 news reporter amy hollyfield joins from the scene. >> it happened at front door, you can see the bullet holes. last night on wilson avenue in the diamond district of oakland, we have a picture of the girl who was killed and this is the 8 -year-old at a sleep over when she was shot and killed. her best friend who is seven was also sheet along with her four-year-old brother and her grandmother and the kids were ambushed according to her stepfather. >> when the doorbell rang the children c

. >> i, you know, read the letter from brayden, and it said that she was born with x and y chromosomes and that she was taking shots of testosterone. it kind of blew me back a little bit. i was like, whoa, you know, i didn't think that would be something you would put off in the first letter that you are meeting someone. you are know what i mean? but she didn't have no shame in it. >> when i wrote her the letter, i drew a picture of us in stripes. >> i have been in here five months. and i have done more thinking i think in this five months than i have done in the past seven years. and brayden seemed like the type of chick that would help me stay on the positive side, you know, that would keep me going, you know, with god and stay out of trouble. is he watching me? >> uh-huh. >> uh-oh. >> dale ly not only does that put makes sure her needs are taken care of. >> i put money on her books the other day too. her family is mad at her for being here. they don't. >> she started putting money on my books. so i found out, you know, that she was a little bit more serious than what i had taken her

patients but the data that was submitted that came from hundreds of patients so it is also about the chromosomes if you use 10 patients it is like studying twins it away by used 10 patients then gave a conditional approval that everybody would have gotten the drug a lot faster. possibly. things like that are in the works but it is difficult to get them working. >> so to come up with the designation status to fast-track to put the company's in contact with the data to shepherd it through very quickly but with these targeted drugs drugs, with cml the package is about 1,000 patients but the sabres on the of the first hundred is the save as a last hundred so if we could have taken the first 100 in reality this could have been in the market one year not to the half. and still holding up for the fda approval. but when they are willing to roof when it is as devastating as cancer. >> one last question. >> in the future, will there be incredible vaccines against specific cancers if you have a panacea you could avoid to get it in the possibility of old age. >> there is one of the present -- prevents 70% o

stanwood first, there are some genetic conditions, chromosomal abnormalalities that are difficult totil after this period of 22 weeks. first of all, is that common? and what would happen in a situation if these restrictions are in place? >> i think that's a very concerning point that you bring up in that a large part of my practice, when i have patients referred to me for second trimester abortions has to do with desired pregnancies where they've gotten terrible news. most ultrasounds that are done to detect abnormal fetal anatomy are done in about 20 weeks gestation so that patients thought that they were having a normal pregnancy and then they got devastating news. and part of the concern with these restrictions is that sometimes the news that they get is preliminary, they need a second opinion, they need to see additional experts, they need to have testing, maybe chromosomal testing like an amniocentesis and to have an unfounded, arbitrary restriction on that process robs patients of the time and dignity they need to come to grips with the situation and make the best decision for

now, researchers say they're able to shut down the extra chromosome that causes it, effectively turningone it with cells grown in the lab. but a sign that gene therapy may work. >>> a big mistake in ft. worth, texas. city workers supposed to condemn a house. but instead, theyer to down the house next door. quite a shock, you might imagine for the owners, when they pulled up to find their house missing. the city, trying to figure out just what went wrong. >>> and now, here's diane sawyer with a preview of tonight's "world news." diane? >> and a good morning to you, josh. tell everyone at "gma" our real money people is back on the case tonight. we've already saved families $5,000. this week alone. and no one will want to miss tonight because we have easy and genius tips to save you money on electricity, right now, when the air conditioner's returning. see you tonight on "world news." >> diane says hello, all. of course, we will be watching. we've seen a flood of feel-good soldier reunions over the years. love them. they have friends of the program. but this may be the very best yet. watch

. >> one of the new genes in als chromosome 9 has an unique defect. i call it chewing gum sticking offense. that deprives the cell of what it can normally do. >> reporter: the hope is in stem cell research. >> we have patients who can look at those cells and see the bad dna, with these therapies we can watch those stickiness go away completely. >> you're inject into the spinal cord and basically saying go fix this. find the motor neurons. >> reporter: others are treating similar diseases like m.s. one of the big challenges is figuring out how people get als in the first place. >> the vast majority of als is sporadic, that's a medical term that means it just happens. >> reporter: als is considered a rare disease in part, because patients don't live long enough to be counted. >> if you develop a disease and you die within a year or two or three or four, you just don't develop the population. >> it can be much your underdiagnosed than people realize. >> reporter: for augie and lynn, it's an an eight-year-old time. >> it's a privilege to walk with somebod

of most of us who live in america is some little chromosome that said there is a courage to move and a courage to come, and i think it makes us better for it. i think immigration is one of the most important parts of america, and thank goodness immigration continues because it brings to our shores amazing people, new generations of leaders who found companies and work hard so that their children and their children's children will do better. if that is a fact about america and our history of immigration, there is also another fact. there have always been haters, people who hate immigrants. i don't know when it started, maybe after the mayflower landed, the folks got off and said please don't send us any more, but it's been part of american history and part of american political history and part of the united states congress. i was reading a book as we started to debate this question of immigration reform entitled "coming to america" by roger daniels, and it's a history of immigration in america, and they speak of a member of the house of representatives in 1924 named albert johnson. h

an abnormal number of different chromosomes.the miscarriage rate and avoid the heart break of getting to 16 weeks and finding out your baby have downs and making a tough decisions that patients make. some keep, some don't. it's challenging. >> there's doctors in jamie's field that will put in five or six embryos and wait to see what happens. the uterus is not a condominium. you want one or two and you want to pick them as brilliantly as possible. if you know that mother nature is not going to be good host to the bad ones and you can figure that out before you implant them, this is a huge step forward. >> that's good news. thank you so ahead. all the consumer news you can use, plus you always get what you pay for when it comes to mail order food? jean chatzky has done online shopping, and she'll tell us the truth. wheat underneath the blanket? we'll find out after this. it's . of course it's your fault and i'm not punishing myself. i'm having dannon oikos zero per cent fat yogurt; twice the protein of regular low fat yogurt. that

my son cole is learning well, even though he has a 21st chromosome, otherwise known as down syndrome this bill limits the percentage of students to whom schools can administer an alternate assessment aligned to alternate standards. without this cap, i believe students will abuse their authority and students will suffer. i believe we can return greater flexibility to the states and still maintain key protections for students like cole. flexibility for states is not mutually exclusive of accountability. at this point i'd like to yield to the gentleman from mississippi, mr. harper. mr. harper -- the chair: the gentleman from mississippi is recognized. mr. harper: i rise in support of the amendment by the gentlewoman from washington. like her i'm the parent of a child with special needs. son issue my 24-year-old livingston has fragile x syndrome and we know what we have done to push our children into mainstream america. we cannot give kids with developmental disables the tools they need to become employed and less dependent on government services without the most appropriate education po