the majority of its sales from cognac shire. 22% lower yesterday and living a third of its value in two biggest two day to client since march 2002. recommending its shareholders vote against the $51 billion takeover of shire. that is amidst concerns of tax rule changes in the u.s.. shire falling once again as is nestle. 2% lower today. sales that missed analyst estimates. it calls into question analyst targets of 5% and nestle targets of 5% growth this year, the asian market becoming more challenging. deflation is eroding. growth targets for this year is 5%. will it reach that target? 2%.le down by >> here are the top headlines. european equities are bouncing back this morning, but in asia japan dropped 11% from the latest high in september. asthe u.s., the smp regained much as 3% and a second confirmed case of ebola. blame everything is the line for yesterday. looking at the biggest bailout and history as it risks falling apart. a month-long selloff has pushed bonds to a level that could cut grease off from the market. it is official, their recommending shareholders vote against the ta